The peroxidase database
Entry information :
Entry ID 5304
Creation 2007-04-30 (Marcel Zamocky)
Last sequence changes 2007-04-30 (Marcel Zamocky)
Sequence status complete
Reviewer Christophe Dunand
Last annotation changes 2007-05-31 (Christophe Dunand)
Peroxidase information
Name AaeDuOx01
Class Dual oxidase    [Orthogroup: DuOx001]
Taxonomy Eukaryota Metazoa Arthropoda Insecta Culicidae Aedes External Link
Organism Aedes aegypti (Yellowfever mosquito)    [TaxId: 7159]
Cellular localisation N/D
Tissue type Whole animal
Inducer N/D
Repressor N/D
Best BLASTp hits
Perox score E-value AaeDuOx01
start..stop
S start..stop
DmDuOx01 2719 0 11..1486 1..1475
AmelDuOx01 2459 0 13..1486 17..1492
NviDuOx01 2321 0 34..1486 14..1451
MincDuOx01 1356 0 6..1485 58..1559
Literature and cross-references
Literature Loftus BJ, Neve VM, Wortman JR, Severson DW, Collins F, Galagan J, Devon K, Henn MR, Jaffe D, Rounsley S, DeCaprio D, Kodira C, Lander E, Crawford M, Fraser CM "The Genome Sequence of Aedes aegypti (strain Liverpool)." Submitted in 2005 to EMBL/GenBank/DDBJ databases.
Zamocky M et al. (2007) Phylogenetic relationship in the peroxidase-cyclooxygenase superfamily (in preparation).
DNA sequence http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?otool=icaumtlib&db=nucleotide&val=AAGE02012569
Protein ref. UniProtKB: Q171Q3
Cluster/Prediction ref. UniGene: Aae.12310
Protein sequence
Sequence Properties
first value : protein
second value (mature protein)
Length (aa) %sProtein length in amino acid1486
PWM (Da) %sMolecular Weight of protein
Protein Mw is calculated by the addition of average isotopic masses
of amino acids in the protein and the average isotopic mass of one water molecule.
Molecular weight values are given in Dalton (Da).
172090.33 Transmb domain %sTransmembrane domain
Calculation done with TMHMM
The topology is given as the position of the transmembrane helices
separated by i if the loop is on the inside or o if it is on the outside.
For example i7-29o44-66i87-109o means that it starts on the inside,
has a predicted TMH at position 7 to 29, the outside, then a TMH at position 44-66 etc.
o576-598i978-1000o1015-1037i1066-1088o1118-1140i1152-1174o
PI (ph)%sIso electric point of protein
Calculation done with EMBOSS parameters.
Please see Dataset for pKi calculation for more information
8.46
Sequence
Send to BLAST
Send to Peroxiscan
.........1 .........2 .........3 .........4 .........5 .........6 .........7 .........8 .........9 .........0 .........1 .........2
MMYIWTKDKR LMSHVEKQRY DGWYNNLAHP DWGAVDNHLT RKAPPAYSDG VYVLAGSSRP SPRKLSRLFM RGKDGLPSMH NRTAILAFFG QVVTNEIVMA SESGCPIEMH RIEIEKCDEM  YDRECRGDRY IPFHRAAYDR NTGQSPNAPR EQINQMTAWI DGSFIYSTSE AWLNAMRAFQ DGLLLTDKDG TMPVKNTMRV PLFNNPVPHV MRMLSPERLY LLGDPRTNQN PALLTFAILL  LRWHNVVAKR VRKQHRDWTD EEIFQRARRV VVASLQNVIT YEYLPAFLDA ELPPYTGYKA DTHPGVSHMF QAAAFRFGHS LIPPGLFRRN GRCDFRKTNM DYPALRLCST WWNSNDVLDD  TPIEEFLMGM ASQIAEREDP LLCSDVRDKL FGPMEFSRRD LGALNIMRGR DNGLPDYNTA RVAYKLPKKK TWRDINPEVF ERQPELLNLL IETYENRLDN VDVYVGGMLE SDGKPGELFT  AVIIDQFTRV RDADRFWFEN EDNGIFTKEE IAELRKITMW DIIVNSTDID PDEIQKDVFH WSEGDPCPQP EQLNATLLEP CNYLEGYDYF SGSELAYIYS CVFLGFVPIL CAGAGYCVIK  LQNSRRRKLK IKQEALKNAG NSKQSVEKMV AREWLHANHK RLVTVKFGPE AAIYTVDRKG EKLRTFSLKN VDVVTVEQSQ ENYKKKKPYI LLRVPSDHDL VLELESNSAR RKFVKKLEDF  LLLHKKDMTF VEVPRDIMLA KAETRERRQK RLEHFFREAY ALTFGLRPGE RRRRSDASVD GEVMTVMRTS LSKSEFAAAL GMKPDDMFVR KMFNIVDKDQ DGRISFQEFL ETVVLFSRGK  TDDKLRIIFD MCDNDRNGVI DKGELSEMMR SLVEIARTTS VTDTQVKELI DGMFQDVGLE HKNHLTYQDF KLMMKEYKGD FVAIGLDCKG AKQNFLDTST NVARMTSFHI EPPSDARRNW  MQEKWDSYTT FLEENRQNIF YLFLFYVITI VLFVERFIHY SFMAEHTDLR HIMGVGIAIT RGSAASLSFC YSLLLLTMSR NLITKLKEFP IQQYIPLDSH IQFHKIAACT ALFFSLLHTV  GHIVNFYHVS TQSIENLKCL TKEVHFTSDY RPDITYWLFQ TVTGVTGVML FVIMCIIFAF AHSTIRKKAY KFFWNAHSLY IVLYALCLIH GLARLTGAPR FWLFFIGPGI VYTLDKIVSL  RTKYMALDVI ETDLLPSDVI KIKFYRPPNL KYLSGQWVRL SCTEIKPEEM HSFTLTSAPH ENFLSCHIKA QGPWTWKLRN YFDPCNYNPD DQPKIRIEGP FGGGNQDWYK FEVAVMVGGG  IGVTPYASIL NDLVFGTSTN RYSGVACKKV YFLWICPSHK HFEWFIDVLR DVEKKDVTNV LEIHIFITQF FHKFDLRTTM LYICENHFQR LSKTSMFTGL KAVNHFGRPD MSSFLKFVQK  KHSYVSKIGV FSCGPRPLTK SVMSACDEVN KGRKLPYFIH HFENFG 

Retrieve as FASTA  
Remarks Complete sequence from genomic (12 introns) and 6 ESTs (only 3' end). Contig positions: 189262-144794. Strain="Liverpool". Region 16-541 peroxidase domain; region 809-915 EF calcium binding motif; region 1021-1168 Ferric reductase like transmembrane component; region 1214-1302 FAD-binding domain; region 1311-1466 NAD binding domain
 

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