The peroxidase database
Entry information :
Entry ID 5408
Creation 2007-06-14 (Christophe Dunand)
Last sequence changes 2007-06-14 (Christophe Dunand)
Sequence status complete
Reviewer Qiang Li
Last annotation changes 2012-08-13 (Qiang Li)
Peroxidase information
Name (synonym) RnoNOx01 (NOX-1 / NOH-1 / MOX1 / Noh1)
Class Ancestral NADPH oxidase    [Orthogroup: NOx001]
Taxonomy Eukaryota Metazoa Chordata Mammalia Muridae Rattus External Link
Organism Rattus norvegicus (Norway rat)    [TaxId: 10116]
Cellular localisation N/D
Tissue types Adipose tissue
Brain
Eye
Gastrointestinal tract
Lung
Inducer N/D
Repressor N/D
Best BLASTp hits
Perox score E-value RnoNOx01
start..stop
S start..stop
MmNOx01 1059 0 1..563 1..563
HsNOx01 939 0 1..563 1..564
CfaNOx01 939 0 1..563 1..564
MmulNOx01 923 0 1..563 1..564
Literature and cross-references
Literature Suh Y.-A., Arnold R.S., Lassegue B., Shi J., Xu X., Sorescu D., Chung A.B., Griendling K.K., Lambeth J.D. Cell transformation by the superoxide-generating oxidase Mox1. Nature 401:79-82(1999).
Protein ref. UniProtKB: Q9WV87
DNA ref. GenBank: AAHX01113105
Cluster/Prediction ref. UniGene: Rn.170541
Protein sequence
Sequence Properties
first value : protein
second value (mature protein)
Length (aa) %sProtein length in amino acid563
PWM (Da) %sMolecular Weight of protein
Protein Mw is calculated by the addition of average isotopic masses
of amino acids in the protein and the average isotopic mass of one water molecule.
Molecular weight values are given in Dalton (Da).
64987.05 Transmb domain %sTransmembrane domain
Calculation done with TMHMM
The topology is given as the position of the transmembrane helices
separated by i if the loop is on the inside or o if it is on the outside.
For example i7-29o44-66i87-109o means that it starts on the inside,
has a predicted TMH at position 7 to 29, the outside, then a TMH at position 44-66 etc.
o10-32i45-67o104-123i167-189o204-226i315-334o391-413i
PI (ph)%sIso electric point of protein
Calculation done with EMBOSS parameters.
Please see Dataset for pKi calculation for more information
8.78
Sequence
Send to BLAST
Send to Peroxiscan
.........1 .........2 .........3 .........4 .........5 .........6 .........7 .........8 .........9 .........0 .........1 .........2
MGNWLVNHWL SVLFLVSWLG LNIFLFVYVF LNYEKSDKYY YTREILGTAL ALARASALCL NFNSMVILIP VCRNLLSFLR GTCSFCNHTL RKPLDHNLTF HKLVAYMICI FTAIHIIAHL  FNFERYSRSQ QAMDGSLASV LSSLFHPEKE DSWLNPIQSP NVTVMYAAFT SIAGLTGVVA TVALVLMVTS AMEFIRRNYF ELFWYTHHLF IIYIICLGIH GLGGIVRGQT EESMSESHPR  NCSYSFHEWD KYERSCRSPH FVGQPPESWK WILAPIAFYI FERILRFYRS RQKVVITKVV MHPCKVLELQ MRKRGFTMGI GQYIFVNCPS ISFLEWHPFT LTSAPEEEFF SIHIRAAGDW  TENLIRTFEQ QHSPMPRIEV DGPFGTVSED VFQYEVAVLV GAGIGVTPFA SFLKSIWYKF QRAHNKLKTQ KIYFYWICRE TGAFAWFNNL LNSLEQEMDE LGKPDFLNYR LFLTGWDSNI  AGHAALNFDR ATDVLTGLKQ KTSFGRPMWD NEFSRIATAH PKSVVGVFLC GPPTLAKSLR KCCRRYSSLD PRKVQFYFNK ETF 

Retrieve as FASTA  
Remarks Complete sequence from genomic (chromo X, 14 introns), 2 mRNA and 9 ESTs. Two partial DNA contigs: AAHX01113105 and AAHX01113107. Strain="BN; Sprague-Dawley". NADH/NADPH mitogenic oxidase subunit P65-MOX.
 

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