Entry information : HsDuOx02 (DUOX2 / LNOX2 / THOX2)
Entry ID 3338
Creation 2006-07-26 (Christophe Dunand)
Last sequence changes 2010-10-18 (Myriam Duval (Scipio))
Sequence status complete
Reviewer Catherine Mathe
Last annotation changes 2015-12-10 (Catherine Mathe)
Peroxidase information: HsDuOx02 (DUOX2 / LNOX2 / THOX2)
Name (synonym) HsDuOx02 (DUOX2 / LNOX2 / THOX2)
Class Dual oxidase    [Orthogroup: DuOx001]
Taxonomy Eukaryota Metazoa Chordata Mammalia Hominidae Homo
Organism Homo sapiens (human)    [TaxId: 9606 ]
Cellular localisation N/D
Tissue type N/D
Inducer N/D
Repressor N/D
Best BLASTp hits
Perox score E-value HsDuOx02
start..stop
S start..stop
PtroDuOx02 3054 0 1..1548 1..1547
CfaDuOx02 2775 0 1..1548 1..1571
BtDuOx02 2728 0 1..1548 1..1545
SscDuOx02 2724 0 1..1548 1..1545
Gene structure Fichier Exons
ExonStart..EndSize ExonStart..EndSize ExonStart..EndSize ExonStart..EndSize
N° 1 45405540..45405609 70 N° 2 45405185..45405274 90 N° 3 45404752..45404916 165 N° 4 45403966..45404153 188
N° 5 45403582..45403783 202 N° 6 45403309..45403475 167 N° 7 45402848..45402908 61 N° 8 45402626..45402722 97
N° 9 45402088..45402178 91 N° 10 45401722..45401824 103 N° 11 45400987..45401150 164 N° 12 45400245..45400420 176
N° 13 45399543..45399661 119 N° 14 45399030..45399167 138 N° 15 45398726..45398839 114 N° 16 45398323..45398525 203
N° 17 45397841..45398026 186 N° 18 45396338..45396563 226 N° 19 45396158..45396251 94 N° 20 45393991..45394187 197
N° 21 45393403..45393472 70 N° 22 45392953..45393036 84 N° 23 45392248..45392426 179 N° 24 45391860..45392090 231
N° 25 45391581..45391680 100 N° 26 45390207..45390256 50 N° 27 45389812..45389939 128 N° 28 45389436..45389589 154
N° 29 45388026..45388258 233 N° 30 45387635..45387793 159 N° 31 45387134..45387289 156 N° 32 45386761..45386889 129
N° 33 45386348..45386470 123  
complement(join(45386348..45386470,45386761..45386889,45387134..45387289,4538763 5..45387793,45388026..45388258,45389436..45389589,45389812..45389939,45390207..4 5390256,45391581..45391680,45391860..45392090,45392248..45392426,45392953..45393 036,45393403..45393472,45393991..45394187,45396158..45396251,45396338..45396563, 45397841..45398026,45398323..45398525,45398726..45398839,45399030..45399167,4539 9543..45399661,45400245..45400420,45400987..45401150,45401722..45401824,45402088 ..45402178,45402626..45402722,45402848..45402908,45403309..45403475,45403582..45 403783,45403966..45404153,45404752..45404916,45405185..45405274,45405540..454056 09))


exon

Literature and cross-references HsDuOx02 (DUOX2 / LNOX2 / THOX2)
Literature De Deken X., Wang D., Many M.-C., Costagliola S., Libert F., Vassart G., Dumont J.E., Miot F.Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family. J. Biol. Chem. 275:23227-23233(2000).
Protein ref. UniProtKB:   Q9NRD8
DNA ref. GenBank:   NC_000015.9 (45405609..45386348)
Cluster/Prediction ref. UniGene:   Hs.71377
Protein sequence: HsDuOx02 (DUOX2 / LNOX2 / THOX2)
Sequence Properties
first value : protein
second value (mature protein)
Length (aa):   %s   1548 (1523)
PWM (Da):   %s   175078.87 (172586.5) Transmb domain:   %s   o600-622i1041-1063o1078-1100i1147-1169o1184-1206i1219-1241o (o575-597i1016-1038o1053-1075i1122-1144o1159-1181i1194-1216o)
PI (pH):   %s   7.9 (7.83) Peptide Signal:   %s   cut: 26 range:26-1548
Sequence
Send to BLAST
Send to Peroxiscan
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
MLRARPEALMLLGALLTGSLGPSGSQDALSLPWEVQRYDGWFNNLRHHERGAVGCRLQRRVPANYADGVYQALEEPQLPNPRRLSNAATRGIAGLPSLHNRTVLGVFFGYHVLSDVVSVETPGCPAEFLNIRIPPGDPVFDPDQRGDVVLPFQRSRWDPETGRSPSNPRDANQVTGWLDGSAIYGSSHSWSDALRSFSGGQLASGPDPAFPRDSQNPLLMWAAPDPATGQNGPRGLYAFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYNIAVYEWLPSFLQKTLPEYTGYRPFLDPSISPEFVVASEQFFSTMVPPGVYMRNASCHFRKVLNKGFQSSQALRVCNNYWIRENPNLNSTQEVNELLLGMASQISELEDNIVVEDLDYWPGPGKFSRTDYVASSIQRGRDMGLPSYSQALLAFGLDIPRNWSDLNPNVDPQVLEATAALYNQDLSQLELLLGGLLESHGDPGPLFSAIVLDQFVRLRDGDRYWFENTRGLFSKKEIEDIRNTTLRDVLVAVINIDPSALQPNVFVWHGAPCPQPKQLTTDGLPQCAPLTVLDFFEGSSPGFAITIIALCCLPLVSLLLSGVVAYFRGREHKKLQKKLKESVKKEAAKDGVPAMEWPGPKERSSPIIIQLLSDRCLQVLNRHLTVLRVVQLQPLQQVNLILSNNRGCRTLLLKIPKEYDLVLLFSSEEERGAFVQQLWDFCVRWALGLHVAEMSEKELFRKAVTKQQRERILEIFFRHLFAQVLDINQADAGTLPLDSSQKVREALTCELSRAEFAESLGLKPQDMFVESMFSLADKDGNGYLSFREFLDILVVFMGSPEDKSRLMFTMYDLDENGFLSKDEFFTMMRSFIEISNNCLSKAQLAEVVESMFRESGFQDKEELTWEDFHFMLRDHDSELRFTQLCVKGGGGGGGIRDIFKQNISCRVSFITRTPGERSHPQGLGPPAPEAPELGGPGLKKRFGKKAAVPTPRLYTEALQEKMQRGFLAQKLQQYKRFVENYRRHIVCVAIFSAICVGVFADRAYYGFASPPSDIAQTTLVGIILSRGTAASVSFMFSYILLTMCRNLITFLRETFLNRYVPFDAAVDFHRWIAMAAVVLAILHSAGHAVNVYIFSVSPLSLLACIFPNVFVNDGSKLPQKFYWWFFQTVGMTGVLLLLVLAIMYVFASHHFRRRSFRGFWLTHHLYILLYALIIHGSYALIQLPTFHIYFLVPAIIYGGDKLVSLSRKKVEISVVKAELLPSGVTYLQFQRPQGFEYKSGQWVRIACLALGTTEYHPFTLTSAPHEDTLSLHIRAVGPWTTRLREIYSSPKGNGCAGYPLYLDGPFGEGHQEWHKFEVSVLVGGGIGVTPFASILKDLVFKSSLGSQMLCKKIYFIWVTRTQRQFEWLADIIQEVEENDHQDLVSVHIYVTQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSITHFGRPPFEPFFNSLQEVHPQVRKIGVFSCGPPGMTKNVEKACQLVNRQDRAHFMHHYENF*

Retrieve as FASTA  
Remarks Complete sequence from genomic (chromo 15, 32 introns), 5 cDNA and 60 ESTs.
DNA
Send to BLAST
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
ATGCTCCGTGCAAGACCAGAGGCACTGATGCTCCTGGGAGCTCTTCTGACTGGATCCCTGGGTCCATCGGGCAAGTATCAGGCTCCTCTAGCGGCGGGGTGTTCCCCAGGATCCCTGGGA
GGTGGGGCGGGGAGAGGTGCGGCAAGCGGCTCCCTGAGACTGGAAGGTCATTTCGCCGTGCAGCTCAGCGGGATGGGAAACTTCCCAGTGCGGCCCGACACTTGGGTCCGGTTAGGGGCG
CTCCGCGAGCTGGGGAAGGACTGGCCAAGGCCTTCGTTGCTCGGGAGGGGTAGCTGGGAGCGTAGTGCTGAGGAGGCCCTTCTCTGTGCCCACAGGCAGTCAGGACGCACTCTCACTGCC
CTGGGAAGTGCAGCGCTATGACGGCTGGTTTAACAACCTGAGGCACCACGAGCGTGGTGCTGTTG
GTGCGTTCTGGGGGCCCGGGCGTGCTGGGGCCGTGGCTCGCGAAGGGCCGGGGCG
CGAAAGGCCCTGAGCGGGGAATCTGCGGGGAACACGCGCCCAGCAGCTCCGCTGCCTACACAGCGCAATCTTATGCGCTCCCGGGGCCAAGAGACCCTTGAGGGAAGGTTCTGTCAGTGA
AGTGGGATGGGGGTTGAGGGAGGCTTAGGGAGAGGTTTGGGGGATCCTAGGGGATGGAGTGCTTAGACAGAGCCCCGCTCCCTGCCTCCGCAGGCTGCCGGTTGCAGCGCCGCGTACCAG
CCAATTACGCCGACGGTGTGTATCAGGCTCTGGAGGAGCCGCAGCTGCCCAACCCGCGCCGGCTCAGCAACGCAGCCACGCGGGGCATAGCCGGCCTGCCGTCGCTCCACAACCGCACCG
TACTGGGGGTCTTCTTTG
GTGAGGGCAAAGGGGGAGACCAGTGGGGTTGATCTGGCGCTCTGCTCAGCCTGGGGGAGGGGCCAGATCCCGTCTGCGAGTCCACAGGAGACCCATCCGACT
CCCAACCACTTCCTCTCTACGCAGCACTTCGAGACTGCCTTCATCTCGGAGAGATTTTGGGATGTTGATACAGAGATATTTGCTCTGTATCTAACCTTTCTCTTACGCCTTATTCCAACC
TAGGGGTGTCACTGGACCCCCATTATAGCTCTTGGGAACTGAGCTCCCCAGCCACCGCTCTCCTCACCGTGTGTTTGTAACCATTTTACCTCCCCCTAGCCCAGAGGGAGGAGGACTGAC
TTGGGGTACCCCTACATAAATTATATCATTTTGATTCTCACAACAGCTTTATGAATTGAGTAGGAAGGGAACTCACTATAGTCTTACTTTGCAGATTAGAAAATTGAGGCTACCTGGGGC
TAACGTGCAGAGCTGGTGGCGGAGCTGGCACTGGGACCTCTGTCTTTTGGCTCCTGAGGACACTTGGAGGCCGCCCTGGCCGTGGGGAGGGCGCAATACGGACGGTTTGTCACGTATTGG
CGCCCCATGCCCGCAGGCTACCATGTTCTTTCCGACGTGGTGAGCGTGGAAACGCCCGGTTGCCCCGCCGAGTTCCTCAACATCCGCATCCCACCTGGAGACCCCGTGTTCGACCCCGAC
CAGCGCGGGGACGTGGTGCTGCCCTTCCAGAGGAGCCGCTGGGACCCCGAGACCGGACGGAGTCCCAGCAACCCCCGGGACCTG
GTGAGGCGGGGAAGGCGGCGGGAAGGGACCGCACCC
CAGCCAGGTGGGGCCTGGGCTTCGGGCCTGGCAGGGCCTGGAGGGGAGAGGCGCCCACTCCCCAGCCGCGGACACCCGCCGGGCCCCGGCCTTCCCTGGCCCGCCGCCGCCTCTCGACCC
GGGCTCACCCGCCGCGTGCCCCGCAGGCCAACCAGGTGACGGGCTGGCTGGACGGCAGCGCCATCTATGGCTCCTCGCACTCCTGGAGCGACGCGCTGCGGAGCTTCTCGGGGGGACAGC
TGGCGTCGGGGCCCGACCCCGCTTTCCCCCGAGACTCGCAGAACCCCCTGCTCATGTGGGCGGCGCCCGACCCCGCCACCGGGCAGAACGGGCCCCGGGGGCTGTACG
GTGAGGCCACAG
GGGCGGGACGGGGCCGGCTGGGGGTCTGCGAGTGTGGGCTCCCCCGATCACGCTACCGCTCGTCTCCTCCCCTGCGCCCCCACGTCGGATGCAGCCTTCGGGGCAGAGAGAGGGAACCGG
GAACCCTTCCTGCAGGCGCTGGGCCTGCTCTGGTTCCGCTACCACAACCTGTGGGCGCAGAGGCTGGCCCGCCAGCACCCAGACTGGGAGGACGAGGAGCTGTTCCAGCACGCACGCAAG
AGGGTCATCGCCACCTACCAG
GTCAGCCGTCCGCGCCCCGCGACGTCCTCCCTTCCGCGTGCAAGCCCACGGGAGACTCCGCTGCCCCATGGAGCTCCCCATCTGTGGACAACCGCCACC
CAGAAACCCCTCCCCAGACAGCCGAGGTCTAGGGAAGCCCCTGTAAATGATAGGGAGGCACGCGCTGTTTATAGGAGAAATCTGGCTGGTGATGATTATTTATCACCTCCCCAACCCCCA
CTCCCTCAAATCCCCTGGTTCCTTGTGGGGACAGGCCTCACACTGCTCCTGTCTGAGTTGCTTCTCCCATGATTGACCCTTCCTGGTCTCATCTCCACACGGAAGCCGTCCTTGGGCTCA
GACCCTTCCAGGCCCCACACCATCCAACTTGTGCCTCCCCTCGCCCCTCTCTGCCCCTCAGAACATCGCTGTGTATGAGTGGCTGCCCAGCTTCCTGCAGAAAACACTCCCGGAGTATAC
AG
GTGAGGGAGCGGGGAAGGAGGACACCTGTGCGGAGAATCCTGAGGGGAAGGAGACAGGTGCCTGTGATGGGAGGATGTGGAGGCAAGAAGCCTGTCTCCCCATCATCACCGTCTCCTT
CCTGCAGGATACCGTCCTTTCCTAGACCCCAGCATCTCCCCGGAATTTGTGGTGGCCTCTGAGCAGTTCTTCTCTACCATGGTGCCCCCTGGTGTCTACATGAGGTGAGGGAGGGGTTGG
CAGAGAGGGGCACCACACTAAGAAAGGTGCAGAATGAGCTGCCTTGGGGGCTGGGGCCTTTCACACTCCTTCGCAGTTTCACTAGAGAAGGGGAAGCAAAAATTTGGGGCCCTGAAACAG
AACCCTGGGGTAAGATGTGTAGGCTTAGTAGGGAAATCTCTCCAGCTCTCCTAAGGGCTGAAATTTGGTGGCTGGGTGTAGGATTTGTCTAGCAGCTGGGTCATTCCCTTCCCTCCTCTC
CCCACCCTACCTGGACTAGGAGCGCACTCTATCTTCAGTAAACGCACATCACCAAATCTCTGCCGTGTTCAAGGAAGTTCCTGGGCCACTGCTCAATCCTAGTGAACCCCCACTGAGTCC
CTCAGCCCACTCAACCCCATCTTTGATTCTTCTCCAAATTCCCTCACCACATCCTTTGTTCTCAATTTCAGAAATGCCAGCTGTCATTTCCGGAAGGTCCTGAACAAGGGTTTTCAAAGC
TCCCAAGCTCTCAGGGTCTGCAACAACTACTGGATTCGGGAG
GTCAGACTGGGGTCAGGGTCAGGGGAAGATGGGTCAAGGTCAGTCTCTTCACACAGGCTGGGAAAAGCAACAATCCCA
GTTCTTGAGTGTTGCTGCCCCAGGTTCATGGGAGATGAAGGGTAGAGGAAATTATCCGGGGACAACAGTTCAAGAGAGTCTGGGACTGGCCAAGGGCCCTTTGTCCTGGGGTACTAAAGT
GGTCCAGGCTGAGAGAGACCGAGTTTTGGGTAGAGGCCTATCTTGAGTGCATTGTTTACTTCCAGAACCCCAATCTGAACAGTACCCAGGAGGTGAATGAGCTGCTGCTGGGAATGGCCT
CCCAGATTTCGGAGTTGGAGGACAACATAGTGGTTGAAGATCTGAGGG
GTGAGCTCAGAGCCAGAAGGGGTGGATGGTAAGGGACCAGGAAGCCTGAGGATCCCTCTGGGTTCATCAATA
GCAGACCTAGGGCGCTCACGATGCAGGAACACAGATACAAACACAGACTTCAAGGAGCCATAAGAAGAAAATGAACTTTGAACTTTTTTTTTTTTTTTGCTTAATTTACACTTTTGTGTT
GCTTTTATTTTAAATTAACTATGTCTGAGTATTGGGGAGGGGTGGTACCACAATCTCTTTGGTGCTTAATTAGGTCTCTAAAGGTTTTCATTCAGCCCTGTCTTGAAACTAGGGAGGCAT
AGGACAGGGAATTTACTGCTTGGTGACTAGAACAGTCTTGAGTCTTAGAGGAAGGGTCTTACTGGAAAAACTGGCTCTGATCACCCATGGTGACATTGGCCTTGCAGCAAGGCAAGGTCA
GCATGGGCACAGATCTCATGTGGATCACTGGGGGTAGCCAGGAGGGAAGAACCGTAGTGCCAATAGTCAGATACAAGGCTGCAGGGCAAAAAAGGATGGAGAGGACAAAGCCCATAGTCT
AGTCTTCTCTCCTCTTCAGATTACTGGCCTGGCCCTGGCAAATTCTCCCGTACAGACTATGTGGCCAGCAGCATCCAACGTGGCCGAGATATGGGGCTGCCCAGCTATAGCCAGGCCCTG
CTGGCCTTTGGGCTGGACATCCCAAGGAACTGGAGTGATCTCAACCCTAATGTGGACCCCCAG
GTCAGGAATAGTAATGATAATAATGGCAGCTAAAGCTTTCCTATGGCAATACTGTTC
CAAACCCTTTACATATGTTGACTCATTTAATCTACATAATAATATTGTAAGGTATGTATAATCATTTTCCCCATTTTACTGATGACATAGTTGGTAAATCATAGAGGAGGGACTTAAATT
CAGCCATCTGATTCCAGAATATATTCCTAACCACTGCATTGTACCATTCCTGCAGGGTGGCTTCTGGGTTGGGTGCCATTGTCCTGTTGCTGCAGGGTCCCACCCCAAGGGCTGTGTGCC
CCTGAAGCTGCTAATCATTGAGGTCAGGCAGGCTGGTGATGGTCACAGGATATGGTCCTAGGGCACCTGACCGTGGTGTTACCGTGGGTAGGGACACACTGATCCTTCCACCAGACTTGT
CCTGCCTGAGGGGGCTTGCCTAAGAAGAGGAAATCAGGCCTGAGCAGCAGCCAGGCAGCGGCTGAGGTTCTGTGCCCGAGGGATGGGGCAACAGTGGCTGCCCTCCGCAGCAAACATACG
CTCACCCCTTATCTCCTGTGGTGCCCCAGGTGCTGGAGGCCACAGCTGCCCTGTACAACCAGGACCTATCCCAGCTAGAGCTGCTCCTTGGGGGGCTCCTGGAGAGCCATGGGGACCCTG
GACCCCTGTTCAGTGCCATTGTCCTCGACCAGTTTGTACGGCTGCGGGATGGTGACCGCTACTGGTTTGAGAACACCAGGAATGG
GTAAGGCTTGCCTGGGCCCCCACCTCAGACTGCTC
CTCAGCCTGAGCCCCAGACCCTCTGTCTAGCCTTAGACAGCCCCTATGAGCCCTTGATTCCCAGTCAGCCCACCACACCCTTCCCAACCCCTCTGGGTCTCTCTTTTTTTCTTCTCTTCT
CTTTTTCTTTTTCTTTTTCTTTTTTTTTTTTTTTTTTTTTTGAGGCAGAGTCTAGCTTTGTCACCCAGGCTGGAGTGCAGTGGCGTGATCTTGGCTCAATGCACCCTCTACCTCCCAGGT
TCAAGTGATTCTCCTGCATCAGCCTCCCAAGTAGCTGGGATTACAGGCATGCACCAACATGCCCGGCTAATTTTTTTAAAAAATATTTTTAGTAGAGATGGGGTTTCACTATGCTGGTCA
GGCTGGTCTCGAACTCCTGACCTCAAGTGATCCACTCGCCTTGGCCTCCCAAAGTGTTGGGATTACAGGCATGAGCCACTGCACCCAGCCCCTCTGGGTCTCTTTTCTCACCTGGGTCCT
TGGGCCTGGGGTTGCTGGAGGCCTGCATCCCCTTCCCATCCCAGTGACTTCTACTTCCTCCAACTTAGGCTGTTCTCCAAGAAGGAGATTGAAGACATCCGAAATACCACCCTGCGGGAC
GTGCTGGTCGCTGTTATCAACATTGACCCCAGTGCCCTGCAGCCCAATGTCTTTGTCTGGCATAAAG
GTGAGTGCCGTGGGAGAACACAAGTGAGTGACAGTGGCCAGAGAAGGATCAAG
ATTGAGGGTGCGGGGGAATCACTTGGTGCTGTCCAGGGAGCCAGGCACCTTCTGTGTTGGGCTAGGAGGCCTGCATTTGGCTGGCTCCCACAGCAGGGACCTCAACTAGCACACAAGCTA
CACCCTACAGTCAAGAAGGGGTGGATGGGGTAGATGCCAAGAGACAGGAAATGAATGGGGACTTTTTGAGGGAGACAGTTTCAGGGAGGTGGGCCTGGGGAAGACAGATGATACCTTGGT
CCTTTATAGGATAGAGGGGAAAGAGGTCTGGCCACATAGCGGGATCCTCAGACTTTGAGGTCTTCCCTGCCCTCTCCCTCAGGTGCACCCTGCCCTCAACCTAAGCAGCTCACAACTGAC
GGCCTGCCCCAGTGTGCACCCCTGACTGTGCTTGACTTCTTTGAAGGCAGCAGCCCTGGTTTTGCCATCACCATCATTGCTCTCTGCTGCCTTCCCTTAG
GTGAGCTCTTAGGCAGCCTC
TCTGCAGACTGGCCCTGCCCCTCATTTCCTGCTGGCCTGAGGGGCTGGCTATTTGGTACCGTTTGAGACCAGGCTCAAGGAACCTCTGGAAGGGAGGGGCCATAGCCTAAGCCACAGTGG
AGCTCTAGGTGAGGGGCTCCCTCCTCACTGTTCCTTCTGATCCACTTCAGTGAGTCTGCTTCTCTCTGGAGTGGTGGCCTATTTCCGGGGCCGAGAACACAAGAAGCTACAAAAGAAACT
CAAAGAGAGCGTGAAGAAGGAAGCAGCCAAAGATGGAGTGCCAG
GTGAGCAGGGGCTGGGCAGAGGAGGGAGGAGGGACGGAGGAGGGGAGAGACAGGAGTCTGGGAGAAAGAACCAAGT
TACAGAGTGAGAGGAAAGCCAAGGCACCTTTAGGGCGCCTGCTCAGACTCACAGAGGAATTGACCTGAAGGCGGGGACCTGGGGACATCTGCTGAACTACCCGGCCCAATTATCCCTTCC
CCAGCGATGGAGTGGCCAGGCCCCAAGGAGAGGAGCAGTCCCATCATCATCCAGCTGCTGTCAGACAGGTGTCTGCAGGTCCTGAACAGGCATCTCACTGTGCTCCGTGTGGTCCAGCTG
CAGCCTCTGCAGCAGGTCAACCTCATCCTGTCCAACAACCGAGGATGCCGCACCCTGCTGCTCAAGATCCCTAAGGAGTATGACCTG
GTATGGCTCGTCCTGCCTCCCCAGCCTGGGCTG
CCCTCACACGACTCCATTATCACAAGCGAGGCCACCCTATCCTCAGCTACAGAGCTCAACTATGACAGCTGATGCTGGGGAGAGGGGCTCCTTTCAGAGGCCCCCAGACACAACCTGACC
CCCTTCGTCCACACACCTGGCCCCAGCCTGGATGGATGGGGAGGAGTTTTCTCTCCTCCCCTCAACCCAAGATCCATTGAGGGGAGGCTGAAGCAGAAGGTCCAGCGAGCTCCCTGCGTC
AGTGCCGCCTTCCTCCCACCCAGGTGCTGCTGTTTAGTTCTGAAGAGGAACGGGGCGCCTTTGTGCAGCAGCTATGGGACTTCTGCGTGCGCTGGGCTCTGGGCCTCCATGTGGCTGAGA
TGAGCGAGAAGGAGCTATTTAGGAAGGCTGTGACAAAGCAGCAGCGGGAACGCATCCTGGAGATCTTCTTCAGACACCTTTTTGCTCAG
GTGCCATGACCTGTGCCTTTTGGAGATGGGT
CCAGCCCCAGAAATGGAGGAAACCTGGGCTGCATAGAACGCCCCTGTGGGTGAACTAAGCTTCCGCTCTATGGCCTGGAGAGAAATAGCCTTGTTTGAATCCTGGCATTGCCACTTTACT
TAGCTCTGTGACCTTAGGCAAGTCACATTATCACTGTTCTGTATCTCTGTTTCCTCATCTATAAAACAGTGATGAAAACTGTATCCATCCCATTGCATTGTTGTGAGGATTCGGTGAGAT
CGTCTACATGAGTGGTACACAGAGGTTGGCCTCTGGACCCGAGAGCATCAGCCTCACCTGGGAACATGTTAGAAATGCACCTACCCAGTTAGACTGAACCAGGAACTCTGTGGGTGGGGC
CTGGCAATCTGTGTTTTAACAAGCTCCCCAGATGATTCAGATACACTCTAATGTTTGAAAAACATTGTTTTATGTACAGTGCTTATTGGCCCAAGTGCCAGGTATGTTGCAGGCATTTAA
CAAACGGTTGTGGCCAGGCGCAGTGGCTCATGCCTATAATCCCAGCACTTTGGGAGGCTGAGGCGGGCAGATCACCTAAGGTCAGGAGTTCGAGACTAGCATGGCCAACATGGTGAAACC
CCATCTCTACTAAAAATACAAAAATTAGCTGGACGTGGTGGCTCACACCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGTGGCGGAGGTTGCAGTGAG
CCAAGATCATGCCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCCATCTCAAAAAAACAAACAAAAAACAATAAATGGTTGTTACATGCGACTTTTAAACTTTTTGTGCAATGGGCA
AATCATAGGCACATGGCAGCCTTATCTGAATTGGCAAGAGAGCACAGCCCCAGCCCCTTCCTGCCTGTCTACCACCATGTCTCTACATCTTCTGTCCCCAGTATAGGCTCTCTCACTTTC
CATTCCCCTTAACTTCGCCCTTCCCCTTCCCTACCCCAGCACCATGCCCACTGCATGAAGTTCCCGGTTCTTGGGCCCAGGGAGAAATGGGCAGGCTGCTAGAGATTTGATTCCCCCGTC
TATAGGACAACAGAGGCCCCAGTCAGTATATCTAAGGATCAGGAGAACCATCAGAGTTTAGCCTTTCTGATTTGGACTTTGGGGAGATATGAAGGGTCACTGAACTGCTTCCAGCATAGG
CTTCACCTCCTTCTCTTTCCCTCCCTCTGCTGCTGCCCGAGTGCAGGTGCTGGACATCAACCAGGCCGACGCAGGGACCCTGCCCCTGGACTCCTCCCAGAAGGTGCGGGAGGCCCTGAC
CTGCGAGCTGAGCAGGGCCGAGTTTGCCGAGTCCCTGGGCCTCAAGCCCCAGGACATGTTTGTGGAGTCCATGTTCTCTCTGGCTGACAAGGATGGCAATGGCTACCTGTCCTTCCGAGA
GTTCCTGGACATCCTGGTGGTCTTCATGAAAG
GTAGGGGGCTGGGAGGTGGCAGGCTATCCAAGAATCCAGGGGTCTTTCAGCAAGGAGATGACCTGCATTCCCTTTTTTCTTCCCAGGC
TCCCCAGAGGATAAGTCCCGTCTAATGTTTACCATGTATGACCTGGATGAGAATGGCTTCCTCTCCAAGGACGAATTCTTCACCATGATGCG
GTATGGGGTGTGCCTTTCTAATCCTGAG
ACTTCCTGGTGTGTTTCAAACAGGAAAACAGGTCCAGTCAGAGGAGGGCTGGCAAAGAGGCTCTGTGGTCATCTGTGCTGAGAGGTGGCCTAAACACTACATCCTAAACTCTCAGAGCAT
CCACCTTCAAATATTTACCTGACTGGCTCCTGCCTCTGGGAGAGTCTCTGTCTGGACTGTCAACACCAGCCAGAAAAGCCTCCCTAGTTAAAAAACGAAAAAAAAAAACCCAACACCAAT
ATGGCCAACGACAAAAATCCACTAATCCCTTTTGGATGCCCTTGGATCTTTGTGAACTATTTTACGGCACGCCCAACACCGTGCTCTACCCAGTGAAACAGTGAATGGATGACCTTGGTT
GCTGCTCCGCTATTCATCACCATGATAGTCAGGAAGAGAAACGTGGAAGGCTTCTCCATATTCCAACCATTCTTTCTTCCTGCATCTTAAGCCCTTTCTGGTTTTGTTGTGCCGGTAAAA
AAAAACAGCTTTGTGCTTCTCATTCCTGAAGACAATGAATGCGTCAGTAACACAGCTCCCCTCCATGCCATAAGGGCAGGGCTTGTTCCCTGTTGAATCCAGCTTCTCTACACTGTGATT
GGCACAGGGCAGGCATTTCATACATAACTAACTGAGTAAGACAAAATGAAATAAGTGAGCAAATGAATACAAAGTATAGATGTAACAGCCCACATTATTTCAATTTTTCTATCCTGTTAA
GCCTTAACATTGCTTTAAGCATTCCCCTTAACTGCTACATTCCTCATATGGTCCAGATACCCCAACTGGACAAGGGCTTCTGAAAGGGCAAAGCTATTGCAGTCTGTACCTCACTGGGTA
TGTCACTGCAGGCCCAGCCCGAGGTGAGGCTCAAGGGAATCTAGGAGAGGGTCCCTGCCTCCAAGGGCTGAGTTCCCACCTTCTTTTTTTGGTTTGTTTGTTTGTTTGTTTTGAGACGGA
GTCACTCTGTCACCCAGGCTGGAGTGCAGTGCCACGATCTCGGCTCACTGCAACCTCCACTGCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGAATTACAGGCATG
TGCCACCACGTCCAGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTAGTCTCGAACTCCTGACCTCAGGGGATCAGCCCGCCTCAGCCTCCTAAAGTGCT
AGGGTTACAGGCGTGAGCCACCACACCTGGTGAATTCCCACCTTCTTGTCCTGTAACTCAGCGTGTATCTTGCTTACTGTCGGTGGGACGATGTTTTTAATGTGATGGTTGTGCTTGCTG
TGTTTTATGGGCCCAGCATGGCACAGCATTGCTGCCGGACCTACACAAACTTGCATAGTCTGTCTTTTCTGTCCCGAGGCACAACCTATGAATAGAGCTTGGCTACTGCAGGTGCCACTG
TGGGTGCTATCAGGTTGGGCATGGAGACGCTCCCGCCTGTGCCCCGGGGTGTTGGCACAAGGAAGCAGCAGCATTGCAGCTAGTTCCCCTCCCTGGCACCTGGCTGCCTGGTGCCCCCAC
TGGACTATGAAAGGGGGAATCCAGGGGTGATGTGGGAGGCATCAACAGAAGAGAGTGGACAGAGAGCCTGCCACGAGAGAGGGCCATGCACACCCTGGACACCCCTGCACTCAGTGGACT
ATCTTCTCAGTTGTAGATGCCCCCTGTTTGAGGGCTGCTTTCTCTGATTGGTCAAGGTCACTTTCAATTCTGTTCTGCCTTTTGAGTCCATGGCTACCCCACCCAGCTTAGTGTCAGCGG
CAGGCTGGATGAGCACCTTCTCAGTGCCATTTCCCGGGTCACTGGTAACCACATTAGATAATCTGGGGCCTGCCCCACCCTGCACCTACCCAAGCCTGACCTTGCTGGGTGACAGGCTGC
TGTGTCTCTGGTCCTCCTCCAGATCCTTCATCGAGATCTCCAACAACTGCCTGTCCAAGGCCCAGCTGGCCGAGGTGGTGGAGTCTATGTTCCGGGAGTCGGGATTCCAGGACAAGGAGG
AGCTGACATGGGAGGATTTTCACTTCATGCTGCGGGACCATGACAGCGAGCTCCGCTTCACGCAGCTCTGTGTCAAAGGTGGAGGTGGAGGTGGAAATG
GTGAGTGTGTGAGGAATGGTT
GGCGTCAGGGAGGGGGGGCGTGTCCTCAAAATGAGAGTTCCTGGTGGGCAGGACCCAGGTCTTACTCTTTTCTGAGTCCTTGGTACCTAGTATAGAACCAAGCACATGTAATTGGGATGG
CACATGTAGGTGTGCAAGTTGCCTAATGCACAATGATACCCACTGAGGTCAAGGAGCAGGTTGAAATCTATCCTACACACTGCTCAAAGCCACCGGCATTGCTCTAAGATGTATCTGGCC
AGAGGAAGAGGCATTGTTTCTTTTACACAAAGGACCTGCAGGGTTGCATCCACCTAAGAGGATGTCCCCTTTCTTGTGCAAAGTTGCCACATTGTCTGCCCTGTGTACAGTGAGTGCTTA
GTCTAGGGAATGAGGGAAACAGGACTCGAGTCAGAGATCTGGACATGACTTTCCCAGAAGGGAGGAGGGCACAGTCTCCCATCCTACCCCACTGCCCTTGTGGGGAAGCCAGTCCTGCCT
CTTGTTCTTTTCTCTAGGTATTAGAGATATCTTTAAACAAAACATCAGCTGTCGAGTCTCGTTCATCACTCGGACACCTGGGGAGCGGTGAGCAGGAATGGGGCTCTGGCAGGTTGGCCT
GGCTGAGCCCCCTGCAGAGAAATGAAGGGAGTAGGACTGGCTGATCAGCCCCTGGTAAAATCAGGCATTTGCCCTTTGAAAGTAGCTCATGGTAGCACAAACATTCCAGCTGCCTCTCTC
ACCCTATGCTGCTCGGATGCTTGGCTCTCTCCCTGCTGCTCCAGGCCAGAATCATTCTACAAAACAAATCATGAGATCCTATTAATTCATTTTGTGCCTTGCCCCCTGCCTGGTACCAGG
AGCCACTCCCTACCTCTACCCCATGCTCTGCCCAGGGAGTTGTTCTCCTGGCTGCAAAGACAAGGGGAGAACAGCCCCATTTCTTTTTCTCAGCTCCCACCCCCAGGGACTGGGGCCCCC
TGCCCCAGAAGCCCCAGAGCTGGGAGGCCCTGGACTGAAGAAGAGGTTTGGCAAAAA
GTGAGTGTCTCCCAAATCCCTGGGCCCAAAGAGACATGGAGAGAAGTCTTAGGGTCCCTAGGC
CCCACCCACATATCCTTGACATATAAGCGACCATCCTGAGTCTCATTCCATTTGTTCCTGACCTGACTGAGAGGTTACAGTGTTGAATGACTTTTCATCCTCTTCCAGCCTCTGCACCCC
ATTCTTCAGGCAAGGGTCCTGGCTCAACAGGATGATAGTAAGGGGTCTCCTGGCTCCTGCCTGCTTTGGGCACAGCCTTGAGGCCTGTGCTGGGATCAGGAAGAAAGAAGGATAAAACAG
ACAGGAGGAGGGGGAGTAGCAGGGAGACAGTGAGTGGGTGGATGGAGCAAAGACAGAAGTAAAGGGTTGGAGGAGGAAGAAGCCCCCAGATTGCTTTTTTCCATTCATCTGTTGTGGCCC
ATCCTGATGCCTGCCAGATCCCCAGGTCACCTTTCATGGAGTGGCATTAAGGGAAGGCCAGAGGGCCCTTACCACACTGCTGCCCTGCCTCCCCTTGCTATAGGGCAGCAGTGCCCACTC
CCCGGCTGTACACAGAGGCGCTGCAAGAGAAGATGCAGCGAGGCTTCCTAGCCCAAAAGCTGCAGCAGTACAAGCGCTTCGTGGAGAACTACCGGAGGCACATCGTGTGTGTGGCAATCT
TCTCGGCCATCTGTGTTGGCGTGTTTGCAGATCGTGCTTACT
GTAAGAGTTCCAGGCTGTGGGCAGTGGGTAGGGAGCAGGCTCTGACCCTTGGAGAGGAGTGGAAAGCCCTCTGATCCT
AAGAGTCTGCATGGGAGAGCCCAGGGCTCGGGACCTTGGCCACCTGTGCCAAGCTGATGTAACCTCACTCCGGCCCCAGACTATGGCTTTGCCTCGCCACCCTCGGACATTGCACAGACC
ACCCTCGTGGGCATCATCCTGTCACGAGGCACGGCGGCCAGCGTCTCCTTCATGTTCTCTTATATCTTGCTCACCATGTGCCGCAACCTCATAACCTTCCTGCGAGAGACTTTCCTCAAC
CGCTATGTGCCTTTTGATGCCGCAGTGGACTTCCACCGCTGGATCGCCATGGCTGCTGTTGTCCTGGCCA
GTACGTGACTCCCAGGCTTCTTCCTCTTTGCTGCAGCACCCTGGGTCTAG
TTGGGGGAAACAGTGGGGAGATGGAACTCCTTATACCTCCATCTCTCCTCCCTATGCCTCCTCTCTCCCTCAGGATCGGAGGTAGAGTCTGTCCTGGTTGGCATCTCTAACAGGGTCTGT
CTCTTCCAGTTTTGCACAGTGCTGGCCACGCAGTCAATGTCTACATCTTCTCAGTCAGCCCACTCAGCCTGCTGGCCTGCATATTCCCCAACGTCTTTGTGAATGATGGGTCAGTTCTGG
GGATGGTTTCTCCTGGGACTCATAGGGTGGGCCCAAGGGTATAATAGAAAAAGAAATAGGCAGGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCG
GATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGCGTGGTGGTGGGCGCCTGTAATCCCAGCTACTCGGGA
GGCTGAGGCAGGAGAATGGCATGAACCCAAGAGGCGGAGCTTGCAGTGAGCCGGGATAGCGCCACTGCAGTCCAGCTTGGGCGAAAGAGTGAGACTCCGTCTCAAAAAAAAAAAAAAAGA
AAGAAATAGGCAGGGCACAATGGCTCACACCTGTAAGCCCAACACTTTGGAAGTCTGAGGCAGGAGGATTGCTTGAGGCCAGGAGTTCCAGACAAGCCTGAACAACAAAGTGAGACTCCA
TCTGTACAAAAAGTAAAAAGATTAGCGGGGCATTGTGGTACACATCTGTAGTCCCAGCTATTCAGGAGGCTGAGGCAGGAGGATTGCTTGAGCCCAGGAGTTTTAGGTTGCAGTGAGCCA
TGATCAGTACCACTGCATTCCAGCCTGGGCGACAGAGCAAGACTCTGTCTTGAAAAAAAAAAAAAGGAAAGAAATAGACAGTCCCAGACACTCAGCAAGAAGCTCAGTGCTAAGCTAGTC
CCCTGGGGGAAGCTGAAAGGTAAATTTCTTGCCTTCAAGAAGGAAGCTGGCTGTGATTGGCCAGGAAAGGTGTTTGGGAGATGAAGTCAGAGACTCTTTCTCATAGATACCTGACACACA
GCTTGCCATCTCTGCCTTCTATCCATTCACTGGACAGACATTTATGCAGCATGTCCCATGTGTCTACCCAGATGCCAGAGTAGGGATGTCAAGATACATGCAGTCATTCAACAACTACTT
ACCGAGATTTGCTGTGTGCCTTGTATTGTTCTAAGCCTAGGGATAGAGCAGTGAATGAAACAAAAATCCCTGCCCTCATGGAGCTTACAGAATAATGAACCAGGGACTCAAGGAAGCAGG
GGTCAACCACAGTAAGAGAGTTCAGGATAACACAGAAGGAAAAATTGCTGAGTACAGAGGGTGGAACCATGGAAGCCTGGGTGCCAAGTTCCTTGGAGGGATCCCTGGCCAACTGGGTGG
AGGCCCCATACCCTCAGCAGTCAGGGCCAGCAGGAAAGGAGTCATGCTGTGTTGTGACAGTGCTGGAGCCCCTCCTGCCCCAGTCAGAGGCTCAAGGTGCCTTTGCCCCCCAGGTCCAAG
CTTCCCCAGAAGTTCTATTGGTGGTTCTTCCAGACCGTCCCAG
GTAGGAAACGTGGGACCTGGGGGTTCTGTCTGAGGACTTCTGCTTTTGTCTCCATCTCTCTGTGAATACTCACTTGT
CTATACTGGCCATGGGGTCTGTTTCTAGCCTTCAGGACAAGCCCCAGCTCAAATCCCTCCAGGCAGGCTTTTCTGGGGGCCCCGGAGGGATGAGAGAGGAAGGAGGGAAGGATAGGGGAA
TGTGCTGTTGTCTTTTCAGCCCAAGCTGAAGTCCTGAGACTACTCACTGGCCCTGTCTTCCTGCCCCCAGGTATGACAGGTGTGCTTCTGCTCCTGGTCCTGGCCATCATGTATGTCTTC
GCCTCCCACCACTTCCGCCGCCGCAGCTTCCGGGGCTTCTGGCTGACCCACCACCTCTACATCCTGCTCTATGCCCTG
GTGAGGGACTTCCCTGGGCCAGCCCATGGAGCAGGGAGCTCA
GGATGGGACAGGAAGGTGAAAGAGGGAGAATTGGATCCAAGATCTCAGAATGAGACTTTGAGATTTAAGACCCCAGACCTCAGCCCTATCTCCCCGGCACAGGCCTAGTGCCTGGGCAAG
AGGGGATGCCGGGCAGGGGCCTGGCTGGGCCTGAGTTGTACTAACTGGCCGTGTCTCCAGCTCATCATCCATGGCAGCTATGCTCTGATCCAGCTGCCCACTTTCCACATCTACTTCCTG
GTCCCGGCAATCATCTATGGAGGTGACAAGCTGGTGAGCCTGAGCCGGAAGAAGGTGGAGATCAGCGTGGTGAAGGCGGAGCTGCTGCCCTCAG
GTATCAGGCCCAGCCTGACCTGGGTC
GGGAGCGACAGAGGCCAAATCTTCAGACATGGGGAGACAGTTCACCAGGTCTCCTGACCCCATCACTGCCTCTGACTCTGTCTCCAAAAACAACAACAACAAAAAACCACTCTCGGGGGT
TCCTGAAGGTTTCCTGATAGAAGTAGACCCAGAAAGGGCTGTGCTTAGCTCCCAGGAGACTTGCAGATGGTGAGAAGTGACCTGAGAAGAGGTGGCTGAACGTGCATACAGAGGGGTTTG
AGGATGGGAAAGGGCCCCACATGTGTGGCCTGGGTGCAGGGGAAGTGCAGGGCAGGAAGCCACATATGCCTGTCCCATTCCTTCTCTCAGAGACAGGCAAATGCCCAGATTGCCAGTCTG
GGTTGTTGAGAGTCAGTGCTGGCCAAAGTCGGGATTGGTATCATCATAGAGGGTGGCAAAAGATGATTTTATGTATCTCAGGACTGTCTAACCTTCAGGACTCATGTTGTAAAAAAATTA
ATCTCATTGCAATGTTATTTCAATTGAGATTACTTAAGGACAAAATCTCAGAGTGGTGTTAGTATGCCTTTCTACTCTCCAGCACTTGCTGATCTCCTTTTTCAATGAAGAGATCAGGCC
TGAGGCTCAGCTATGGTACAAACAGTATCCAGCTAAAATTTGGTAACAAAATATGTTGTCTTCTATGTAGGACACATGATACTGGTTTTCCACTTACCTTAGCAATAAAGTTCCCTGCCA
AGATTAATTGAATTGGAAAAGTTAGTCAATTTAAAGAAAAGTGTTAGATAAATGATAGTGCAGGAGGTGTGTAGAAAGGTAACCCTCAAATGGAGGTCTGGTAGCCACTGAGATGGTCCC
TGGTGAGCCTGAGTCCCTTTACCCAGCAGGTTGGTATTCAAGGCAGTGGTATGAGGCCTGGGCCTTCCATGGGAAGAGGGAGTAGAGAGGAGGAGAGGGGCTGGAACAGGGGAGCAGAGA
AACCCAGCTCTTGCATTACCTGGGAAACAGAGAAGGGGACCCTCCTACTCCCAGCCCCAGGAGCCCCGCTTGCTCAGACCATGTGACTACTCCCCAGGCCTCAGGGGTGTGAAGAGGACA
GGTGCCTATCAGTCCTCAGGTACCAGGAGCAGGCCTTCTCATCTGTGCTTTTCCCTGTCTATGACCTCCAGGAGTGACCTACCTGCAATTCCAGAGGCCCCAAGGCTTTGAGTACAAGTC
AGGACAGTGGGTGCGGATCGCCTGCCTGGCTCTGGGGACCACCGAGTACCACCCCTTCACACTGACCTCCGCGCCCCATGAGGACACACTCAGCCTGCACATCCGGGCAGTGGGGCCCTG
GACCACTCGCCTCAGGGAGATCTACTCATCCCCAAAGGGCAATGGCTGTGCTGGATACCCAAAG
GTGCCCGTCACTGGGAACCCTGCTTCCGGGCCTCTGGCACTGGCAGAGGATCTCTG
CCCTTCCCTATCCTGAGACTAGAAGCTCCAGCCGTCCCAAAGCCAGCCTGGGAGAGGACCGGGGTGCCTCAGAAAAGACTAGGATGTTCTGTATCCTCCCTCTGCCTGTGTCTCCGTTTC
TGGTCTCAGAGCTGGGGCAGGGTCAGGCTCATTTCATCTCCCCCCTCTCTTGGCAGCTGTACCTTGATGGACCGTTTGGAGAGGGCCATCAGGAGTGGCATAAATTTGAGGTGTCAGTGT
TGGTGGGAGGGGGCATTGGGGTCACCCCCTTTGCCTCCATCCTCAAAGACCTGGTCTTCAAGTCATCCTTGGGCAGCCAAATGCTGTGTAAGAAG
GTGAGCATCCCTCCCTCATTCATCA
AATGGGGCATAGGTGGCCGAATTGTGACCCGCATCAAGTGGTGGAGCATGAGAGAAAGCTCCTGGCTCCAGGAACTGAGTCTGAAGGGGTCATTCTTACCCAGTGGTTGAGATGCCAAAC
TTGGAGGGAGGTTGGTGGTATAGCCAGAAGGGCCTCTGCTGGGACCTGTCAGTTGGAAGCCTGGGATCAGGCTGGTGGGTCCTGCCACAGCTTTGGTGTCTGCAGGTGGTCTGGGGCTTC
CCAGCCTCTCAGGTGAAGGCACCTGGGATCTAGGGAGGCTGAACTGAGCTGGGTCCTGATCTCCAGCCCTGTGTCCCCAGATCTACTTCATCTGGGTGACACGGACCCAGCGTCAGTTTG
AGTGGCTGGCTGACATCATCCAAGAGGTGGAGGAGAACGACCACCAGGACCTGGTGTCTGTGCACATTTATGTCACCCAGCTGGCTGAGAAGTTCGACCTCAGGACCACCATGCTA
GTAT
GTCAGGGCCCGCCAGGCAGGGCAACTTGGCGGGCAGATGGATTGGCAGCGTAAGGCAGGATGGCCAGGGCAGGTGGGTGGACGGCCAGGCTGAGCTGGCAGGAGGCACAGAGCTGATGGC
CTGATCCTCAGCCTCCAGCTCCCTCCCCTCCCCATTCTCTGTCTCTTGGGCTATGTGGGCTGGCTCGGGCTGAGTGCTGGCCCTGACTGTCTTTGGTCTGACCTGCCCCTGTGCCCCCAG

TACATCTGCGAGCGGCACTTCCAGAAAGTGCTGAACCGGAGTCTGTTCACGGGCCTGCGCTCCATCACCCACTTTGGCCGTCCCCCCTTCGAGCCCTTCTTCAACTCCCTGCAGGAGGTC
CACCCACAG
GTCAGTCCCACTCCCTCCCACCCTGGGACTCTGGCCTTCTCCTGCCAGGACATCCTGGCCCTGAAGCACCCTGCCACTCTGTTCTGAGCAGAGAACTCCACCCGATTGCCT
GGCCCCAGGATGAGGTCAGCTGTTAAAGGGGGACTTCCACCCCCTCCACGTTAAGCCTCCTCCTCAAGGCCTGGGCTTGAAGCCTTAGTCATTCCAGCCAGGCTCAGGAAGCAGCTTTTC
CCAAGGAGAGTGAGCACCTTTAGGCTGCAGGCCCCTCTCTCTCTCCAATCTCCTGACAGGTGCGCAAGATCGGGGTGTTCAGCTGCGGCCCTCCAGGAATGACCAAGAATGTAGAGAAGG
CCTGTCAGCTCGTCAACAGGCAGGACCGAGCCCACTTCATGCACCACTATGAGAACTTCTGA

Retrieve as FASTA  
CDS
Send to BLAST
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
ATGCTCCGTGCAAGACCAGAGGCACTGATGCTCCTGGGAGCTCTTCTGACTGGATCCCTGGGTCCATCGGGCAGTCAGGACGCACTCTCACTGCCCTGGGAAGTGCAGCGCTATGACGGC
TGGTTTAACAACCTGAGGCACCACGAGCGTGGTGCTGTTG
GCTGCCGGTTGCAGCGCCGCGTACCAGCCAATTACGCCGACGGTGTGTATCAGGCTCTGGAGGAGCCGCAGCTGCCCAAC
CCGCGCCGGCTCAGCAACGCAGCCACGCGGGGCATAGCCGGCCTGCCGTCGCTCCACAACCGCACCGTACTGGGGGTCTTCTTTG
GCTACCATGTTCTTTCCGACGTGGTGAGCGTGGAA
ACGCCCGGTTGCCCCGCCGAGTTCCTCAACATCCGCATCCCACCTGGAGACCCCGTGTTCGACCCCGACCAGCGCGGGGACGTGGTGCTGCCCTTCCAGAGGAGCCGCTGGGACCCCGAG
ACCGGACGGAGTCCCAGCAACCCCCGGGACCTG
GCCAACCAGGTGACGGGCTGGCTGGACGGCAGCGCCATCTATGGCTCCTCGCACTCCTGGAGCGACGCGCTGCGGAGCTTCTCGGGG
GGACAGCTGGCGTCGGGGCCCGACCCCGCTTTCCCCCGAGACTCGCAGAACCCCCTGCTCATGTGGGCGGCGCCCGACCCCGCCACCGGGCAGAACGGGCCCCGGGGGCTGTACG
CCTTC
GGGGCAGAGAGAGGGAACCGGGAACCCTTCCTGCAGGCGCTGGGCCTGCTCTGGTTCCGCTACCACAACCTGTGGGCGCAGAGGCTGGCCCGCCAGCACCCAGACTGGGAGGACGAGGAG
CTGTTCCAGCACGCACGCAAGAGGGTCATCGCCACCTACCAG
AACATCGCTGTGTATGAGTGGCTGCCCAGCTTCCTGCAGAAAACACTCCCGGAGTATACAGGATACCGTCCTTTCCTA
GACCCCAGCATCTCCCCGGAATTTGTGGTGGCCTCTGAGCAGTTCTTCTCTACCATGGTGCCCCCTGGTGTCTACATGAG
AAATGCCAGCTGTCATTTCCGGAAGGTCCTGAACAAGGGT
TTTCAAAGCTCCCAAGCTCTCAGGGTCTGCAACAACTACTGGATTCGGGAG
AACCCCAATCTGAACAGTACCCAGGAGGTGAATGAGCTGCTGCTGGGAATGGCCTCCCAGATTTCGGAG
TTGGAGGACAACATAGTGGTTGAAGATCTGAGGG
ATTACTGGCCTGGCCCTGGCAAATTCTCCCGTACAGACTATGTGGCCAGCAGCATCCAACGTGGCCGAGATATGGGGCTGCCCAGC
TATAGCCAGGCCCTGCTGGCCTTTGGGCTGGACATCCCAAGGAACTGGAGTGATCTCAACCCTAATGTGGACCCCCAG
GTGCTGGAGGCCACAGCTGCCCTGTACAACCAGGACCTATCC
CAGCTAGAGCTGCTCCTTGGGGGGCTCCTGGAGAGCCATGGGGACCCTGGACCCCTGTTCAGTGCCATTGTCCTCGACCAGTTTGTACGGCTGCGGGATGGTGACCGCTACTGGTTTGAG
AACACCAGGAATGG
GCTGTTCTCCAAGAAGGAGATTGAAGACATCCGAAATACCACCCTGCGGGACGTGCTGGTCGCTGTTATCAACATTGACCCCAGTGCCCTGCAGCCCAATGTCTTT
GTCTGGCATAAAG
GTGCACCCTGCCCTCAACCTAAGCAGCTCACAACTGACGGCCTGCCCCAGTGTGCACCCCTGACTGTGCTTGACTTCTTTGAAGGCAGCAGCCCTGGTTTTGCCATC
ACCATCATTGCTCTCTGCTGCCTTCCCTTAG
TGAGTCTGCTTCTCTCTGGAGTGGTGGCCTATTTCCGGGGCCGAGAACACAAGAAGCTACAAAAGAAACTCAAAGAGAGCGTGAAGAAG
GAAGCAGCCAAAGATGGAGTGCCAG
CGATGGAGTGGCCAGGCCCCAAGGAGAGGAGCAGTCCCATCATCATCCAGCTGCTGTCAGACAGGTGTCTGCAGGTCCTGAACAGGCATCTCACT
GTGCTCCGTGTGGTCCAGCTGCAGCCTCTGCAGCAGGTCAACCTCATCCTGTCCAACAACCGAGGATGCCGCACCCTGCTGCTCAAGATCCCTAAGGAGTATGACCTG
GTGCTGCTGTTT
AGTTCTGAAGAGGAACGGGGCGCCTTTGTGCAGCAGCTATGGGACTTCTGCGTGCGCTGGGCTCTGGGCCTCCATGTGGCTGAGATGAGCGAGAAGGAGCTATTTAGGAAGGCTGTGACA
AAGCAGCAGCGGGAACGCATCCTGGAGATCTTCTTCAGACACCTTTTTGCTCAG
GTGCTGGACATCAACCAGGCCGACGCAGGGACCCTGCCCCTGGACTCCTCCCAGAAGGTGCGGGAG
GCCCTGACCTGCGAGCTGAGCAGGGCCGAGTTTGCCGAGTCCCTGGGCCTCAAGCCCCAGGACATGTTTGTGGAGTCCATGTTCTCTCTGGCTGACAAGGATGGCAATGGCTACCTGTCC
TTCCGAGAGTTCCTGGACATCCTGGTGGTCTTCATGAAAG
GCTCCCCAGAGGATAAGTCCCGTCTAATGTTTACCATGTATGACCTGGATGAGAATGGCTTCCTCTCCAAGGACGAATTC
TTCACCATGATGCG
ATCCTTCATCGAGATCTCCAACAACTGCCTGTCCAAGGCCCAGCTGGCCGAGGTGGTGGAGTCTATGTTCCGGGAGTCGGGATTCCAGGACAAGGAGGAGCTGACA
TGGGAGGATTTTCACTTCATGCTGCGGGACCATGACAGCGAGCTCCGCTTCACGCAGCTCTGTGTCAAAGGTGGAGGTGGAGGTGGAAATG
GTATTAGAGATATCTTTAAACAAAACATC
AGCTGTCGAGTCTCGTTCATCACTCGGACACCTGGGGAGCG
CTCCCACCCCCAGGGACTGGGGCCCCCTGCCCCAGAAGCCCCAGAGCTGGGAGGCCCTGGACTGAAGAAGAGGTTTGGC
AAAAA
GGCAGCAGTGCCCACTCCCCGGCTGTACACAGAGGCGCTGCAAGAGAAGATGCAGCGAGGCTTCCTAGCCCAAAAGCTGCAGCAGTACAAGCGCTTCGTGGAGAACTACCGGAGG
CACATCGTGTGTGTGGCAATCTTCTCGGCCATCTGTGTTGGCGTGTTTGCAGATCGTGCTTACT
ACTATGGCTTTGCCTCGCCACCCTCGGACATTGCACAGACCACCCTCGTGGGCATC
ATCCTGTCACGAGGCACGGCGGCCAGCGTCTCCTTCATGTTCTCTTATATCTTGCTCACCATGTGCCGCAACCTCATAACCTTCCTGCGAGAGACTTTCCTCAACCGCTATGTGCCTTTT
GATGCCGCAGTGGACTTCCACCGCTGGATCGCCATGGCTGCTGTTGTCCTGGCCA
TTTTGCACAGTGCTGGCCACGCAGTCAATGTCTACATCTTCTCAGTCAGCCCACTCAGCCTGCTG
GCCTGCATATTCCCCAACGTCTTTGTGAATGATGG
GTCCAAGCTTCCCCAGAAGTTCTATTGGTGGTTCTTCCAGACCGTCCCAGGTATGACAGGTGTGCTTCTGCTCCTGGTCCTGGCC
ATCATGTATGTCTTCGCCTCCCACCACTTCCGCCGCCGCAGCTTCCGGGGCTTCTGGCTGACCCACCACCTCTACATCCTGCTCTATGCCCTG
CTCATCATCCATGGCAGCTATGCTCTG
ATCCAGCTGCCCACTTTCCACATCTACTTCCTGGTCCCGGCAATCATCTATGGAGGTGACAAGCTGGTGAGCCTGAGCCGGAAGAAGGTGGAGATCAGCGTGGTGAAGGCGGAGCTGCTG
CCCTCAG
GAGTGACCTACCTGCAATTCCAGAGGCCCCAAGGCTTTGAGTACAAGTCAGGACAGTGGGTGCGGATCGCCTGCCTGGCTCTGGGGACCACCGAGTACCACCCCTTCACACTG
ACCTCCGCGCCCCATGAGGACACACTCAGCCTGCACATCCGGGCAGTGGGGCCCTGGACCACTCGCCTCAGGGAGATCTACTCATCCCCAAAGGGCAATGGCTGTGCTGGATACCCAAAG
CTGTACCTTGATGGACCGTTTGGAGAGGGCCATCAGGAGTGGCATAAATTTGAGGTGTCAGTGTTGGTGGGAGGGGGCATTGGGGTCACCCCCTTTGCCTCCATCCTCAAAGACCTGGTC
TTCAAGTCATCCTTGGGCAGCCAAATGCTGTGTAAGAAG
ATCTACTTCATCTGGGTGACACGGACCCAGCGTCAGTTTGAGTGGCTGGCTGACATCATCCAAGAGGTGGAGGAGAACGAC
CACCAGGACCTGGTGTCTGTGCACATTTATGTCACCCAGCTGGCTGAGAAGTTCGACCTCAGGACCACCATGCTA
TACATCTGCGAGCGGCACTTCCAGAAAGTGCTGAACCGGAGTCTG
TTCACGGGCCTGCGCTCCATCACCCACTTTGGCCGTCCCCCCTTCGAGCCCTTCTTCAACTCCCTGCAGGAGGTCCACCCACAG
GTGCGCAAGATCGGGGTGTTCAGCTGCGGCCCTCCA
GGAATGACCAAGAATGTAGAGAAGGCCTGTCAGCTCGTCAACAGGCAGGACCGAGCCCACTTCATGCACCACTATGAGAACTTCTGA

Retrieve as FASTA