Entry information : HsGPx04-A
Entry ID 3603
Creation 2007-02-08 (Marcia Pinheiro Margis)
Last sequence changes 2016-06-28 (Harold Duruflé)
Sequence status complete
Reviewer Christophe Dunand
Last annotation changes 2016-06-29 (Christophe Dunand)
Peroxidase information: HsGPx04-A
Name HsGPx04-A
Class Animal glutathione peroxidase    [Orthogroup: Gpx1002]
Taxonomy Eukaryota Metazoa Chordata Mammalia Hominidae Homo
Organism Homo sapiens (human)    [TaxId: 9606 ]
Cellular localisation Mitochondria
Tissue type N/D
Inducer N/D
Repressor N/D
Best BLASTp hits
Perox score E-value HsGPx04-A
start..stop
S start..stop
PtroGPx04 411 2e-149 1..197 1..197
PpyGPx04-A 410 4e-149 1..197 1..197
MnemGPx04 409 7e-149 1..197 1..197
MmulGPx04 409 7e-149 1..197 1..197
Gene structure Fichier Exons
ExonStart..EndSize ExonStart..EndSize ExonStart..EndSize ExonStart..EndSize
N° 1 1..84 84 N° 2 1143..1237 95 N° 3 1323..1467 145 N° 4 1615..1766 152
N° 5 2199..2223 25 N° 6 2335..2416 82 N° 7 2497..2597 101  
join(1..84,1143..1237,1323..1467,1615..1766,2199..2223,2335..2416,2497..2597)


exon

Literature and cross-references HsGPx04-A
Literature Esworthy R.S., Doan K., Doroshow J.H., Chu F.-F. Cloning and sequencing of the cDNA encoding a human testis phospholipid hydroperoxide glutathione peroxidase. Gene 144:317-318(1994).
Protein ref. UniProtKB:   P36969
DNA ref. GenBank:   AF060972.1
Cluster/Prediction ref. Genebank:   2879 UniGene:   Hs.433951
Protein sequence: HsGPx04-A
Sequence Properties
first value : protein
second value (mature protein)
Length (aa):   %s   197 (172)
PWM (Da):   %s   21862.96 (19373.5)  
PI (pH):   %s   8.48 (8.05) Peptide Signal:   %s   cut: 26 range:26-197
Sequence
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.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
MSLGRLCRLLKPALLCGALAAPGLAGTMCASRDDWRCARSMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQ*GKTEVNYTQLVDLHARYAECGLRILAFPCNQFGKEPGSNEEIKEFAAGYNVKFDMFSKICVNGDDAHPLWKWMKIQPKGKGILGNAIKWNFTFGHRLSTVPHRQERLRGEALRTHGGAPGDREGPAPLFLAPQVCGPARAPAHALGAFHRHS

Retrieve as FASTA  
Remarks Complete sequence from genomic (Chromo 19, 6 introns), 19 cDNA and 1048 ESTs. Three Alternative products produced by alternative splicing.
Promoter
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.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
CTGCCTCTGC CACCAAACCA TCCATGACGC CTCTGTGCTG CATCTGGCAG GCCTGAGTCG GGGGCAGTGG CGGGGGCAGG CTCATAGCAC CCCCCAAGTC AACCCGGCCC TGAGTCTGTC  TCTGAAGAAA TACTCAGTGC AGGGTCAGAA AAGGTTAAGA CCTTGAGGAC AACATACAAA TCCCAAGCAC CTAGGCGGGG TAGAGTGGCT CACACCTGTA ATCCCAGCAC TTTGGGAGGC  CGAGGCAGGC GGATCACCTG AGGTCGGGAG TTCGAGACCA GCCTGACCAA CATGGTGAAA GCCCGTATCT ACTAAAAACA CAAAAATTAG CTGGGCGTGG TAGCACATGC CTGTAATCCC  AGCTACTCAG GAGACTGAGG CAGGAGAATC ACTTGAACCC GGAAAGCGGA GGTTGCAGTG AGCTGCGATG GAGCCACTGC ACTCCAGCCT GGGTGACAGA CCAAGACTCC TCAAAAAAAA  AAAAAAAAAT CCAAACCCCT GCCTGTACAG GGGTCAAAGT CCAATCACGG TGACTCAGTT CCCAAGTATG AGATGAGTGT TTCTGTTGCC ACATGTCCAA GCCACGAAGT GAAAAACAGA  GTTGGAAGCC AAGATGTGGG GCAGTATGGG CTCGGGTGTG CCCATACCTT GTAATGTTAG AAGTGTAAGA AAACCCTCCA GACTTGTGTT TATTTTCTGA GCACATACCG CGCGTCCCTG  CGTGGGCAGC TGCCCCTGGG GGTGGGAGCC CAGGAAACTC CAGGTTCTCA GTTAAGTGGT AACTGTCTTG ATGACTCTCA GGTCTCAGTG CCCACATTAT ACAAGCGGCT CAGCAACCAG  ACCCAGGATG GGGAGTCACT GACCCCCTGC GCCCATGGCA GGGGTGAGGG TAGGGACACC CCCATAAGAT GGAGCTGTGA TGAGAAGCAA ACCCAACTCA GTTTGGTTTC ATTTACATTA  AAAAGGCAAA TCCCTTGGCC GGATGCGGTG GCTCACACCT GTAATCCCAG CACTCTGGGA GGCCTAGGCG GGCAGATCAC CTGAGGTCAG GAGTTCGAGA TCAGCCTGGC CAACATGGTG  AAACCCCGTC TCTACTAAAA ATACAAAAAA ATTAGCTGGG TGTGGTGGCT CGCTCGTGTA ATCCCAGCTA CTCAGGAGGC TGAGTCAGGA GAATCGCTTG AACCCGGGGG CTGGGTGGAG  GTTGCAGTGA GCTGAGATAG CGCCACTGCA CTCCAGCCTG GGCAAAAGAG CAAAAAAACT GTGTCTCGGA AAAAAAAAAA AAAAAAAGGC AAATCCCGGC CGAGCCTTTG GCTCACGCAT  GTGATCCCAG CACTTTTGGG AAGCTGAGGC TGGAGGATCA CTTGAGGTCA GAAGTTTGAG ACCAGCCTAG GCAACATAGC GAGACCCCCA TGTCTACAAA ACAATAATTA GCCAGGAATG  GTGGATGAGC CTGTTGTCCC AGCTACTCGG GAAGCAGAGA CGGGAGGTTC GCTTGAGCCT GGGAGGTCGA GGCTGCAGTG TGCCCTGATC GTGCCACTGC ACGTTAGCCT GGGCAACACA  GCAAGACCCC GTGTCTTAAA AAAAAAAAGG TAAATAAGAG TTGGGGACAC TTTTCTGCGA GTTGGAGAAA CCAAACCCCC TCGACGAGTC TTAAGTAGTA TTCTCAGGTT GTCTGGCCTG  CGGCCGCGCT GCTGTCAACC AGCCGGATAA CTGCGCTGCC TCCCGACGCG CCGCCAGCCA GGCCACGGCC TCCTAGACAC AAGCGAGCAT GCGCAGTCGC CAACAACAAG TCCGCACGTC  CGGTCCCGCC CCCCCTTCCC CGCCTTCTTC CCACTCCGGC CTCCCATTGG CTGACGTCGG CGCGAGCGCT CAACACCGAC GCGTCTGACC AATGAGCGCT CTGGAGGGCG TGGCCGTGGG 
AAAGGAGGCG CGGAAAGCCG ACGCGCGTCC ATTGGTCGGC TGGACGAGGG GAGGAGCCGC TGGCTCCCAG CCCCGCCGCG 

Retrieve as FASTA  
Terminator +
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Send to cis Analysis
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
CTCCACAAGT GTGTGGCCCC GCCCGAGCCC CTGCCCACGC CCTTGGAGCC TTCCACCGGC ACTCATGACG GCCTGCCTGC AAACCTGCTG GTGGGGCAGA CCCGAAAATC CAGCGTGCAC  CCCGCCGGAG GAAGGTCCCA TGGCCTGCTG GGCTTGGCTC GGCGCCCCCA CCCCTGGCTA CCTTGTGGGA ATAAACAGAC AAATTAGCCT GCTGGATCTT TCTGCGTAGG GGCTTGGGGG  GCCCTTTTGC CAGGGGCCCC TCCATGTCAG GGCCAGTTGC CGTCAGCTGC CAGGCTGGGG GTGCCATGGA GGTGGCGTGT TGTTGCCCCC TCTTCCTCCA GGCTCGGGGG GCTGTGCTGG  CTGCAGTGCT GGGGTGCAGT GAGATCTGGG CCCGTTGGAC ACCCAGCCCT GGCTCTTAAT CCGTGCAGCC CCACCTGCTG TGCACAGGCA GGGCCTGGTG TAGTGCCGAG TCTTGGAGGA  GATAATTCTA AGTGGCTGTG CTTCCTGGCC CCGGGCCTTA ACTGTTAGGA GGTGGCTACT GGGGCCTCCC CTGGCCAGGA AGCAGAAGTG CAGAGGCCCG AGGAACAGCG TGGCCCTGGT  GCTGGGGATG GGTTGGGCAC CCACACCGGC CCTTGGGGCC TCACCTGGCT GGGGGGTGTG GGGGTGGCTG GGTGGTTACT GTTTGCACAG AGTCCCTCCG TGAGGGCTGG GGATGGACAG  GCCAGGAGGG GCTGGTAGAG CAGTACCAGC CACCGTTCAT GGGACCCGGG GGCTGTCTGG ACACGGCCTG GCTGCCCACC TGCACAGCTA GAGGGACTGC AGCCTGCCAG GGTGGCTGAT  CCCAGCTGCC CCCACTGGGG GTCTGTGGAA TGGACGGTCC ATGGCACCTG CCCCAGACAC TGGGTTGAGA GGTCTGTCTC TCCCAGCCCT CGTCCCCTCT CATCCACATG GGGCCAGCAC 
AGGCAGTGGG CAGAAAGGCC TGGTAACCAG GAGAGCCTGG 

Retrieve as FASTA  
DNA
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.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
ATGAGCCTCGGCCGCCTTTGCCGCCTACTGAAGCCGGCGCTGCTCTGTGGGGCTCTGGCCGCGCCTGGCCTGGCCGGGACCATGGTGAGCTAGCGCCGCGGCCGTTGCCGGCCCGGTGAC
CGTTGGGGCGGGCGCGCGATCCCTGCCTCCGCTCGCCGGCGTGGGGAACCCTCAGGCTCCAGTGACCTTGGTGGGGGGCGTCTGGGGGCTCCCCCTCCCCACCCCCGGCCGGGCACGGAC
GCGGGTGACCGTACTGCGACGCGCTCCGCGGCCCTCCAGGCCGTTGTAGGCGCGCGGGCTGGGGTCGGGGAAGGGGAAGGGGTTGTTCCACGCGCGCGGGTCGTGGTCGGGGAAGGGGCC
GTCCAGGCCGTTGCAGGCGCGCGTGCCGGGGCCGGGGTCGGGGGTCCAGGCTTGCAGGGGGCGGGGTCCGGGACGGCTGGGGCGGAGCTGGACCGTTGAGGGCCACGGCGGGGCGTCTCC
GGGCCGAGCGGGGCTGCTGCGCCCGAGCGGTTGGGGGCGCGGAGGGCTGGAAATCCCGGATCACGCGCCCCCGGGCGCCGCCCCGCCCCCGCACCTTGGCCTAGCGCGGTGGCGTCACAG
TCGCGCAGTCCTGACTACGGCCTCCGGGCCCTTTGTCCCCGCTAGCGGCGCTCGGGGTGGGGGAGCCAGGAGGGGCGGGAGACGGGCGGGTATGGGCCGCGCGGGCGCAGGCTCCCCCGG
GCGCCGCAGGCAGCGGTGCCAGAGCCGGGGCAGGCGGCGGCCGCGAGCCCCTCGGCGGCGGAAGGCCCCAGCGTGCAGGCGCAGGAGGGCGCGGCGCCGGCGGAAGAAGCCCTGTCCCCG
CAGCTTGCGACCGGAGATCCACGAATGTCCCAAGTCCCAGGACCCGGTGCGCGCGGGGCCCCCACACCGGCTAATGTGGCACATTTTGGGGTTGGAACCCTCTCCCGGCCTCCGGGTCTC
CGGTAAAACCGGACCAGAAGTACAAGGGGGCGTGTGCGTTTAAGGAGGAGGAGCGTTCAGGTCTTCAGGGCCGCAGGGCCTCGGTGTCCCCGCCACCGACCCGCTCCCGATCCCTTCCTG
CCTCAGGGTCCCGGGCTCAGCCTCCCGTCCACGCTCCCTGCTCAGCTTCCTTTGCCTTGCAGTGCGCGTCCCGGGACGACTGGCGCTGTGCGCGCTCCATGCACGAGTTTTCCGCCAAGG
ACATCGACGGGCACATGGTTAACCTGGACAAGTACCG
GTGGGCGCTCGCCTGGGGTGGGGCGCGGGGTCGGGCCCTGGGAGGGGGCCGTGTTCTTCTGCGCTGACGCCGCCGATCCTCGC
AGGGGCTTCGTGTGCATCGTCACCAACGTGGCCTCCCAGTGAGGCAAGACCGAAGTAAACTACACTCAGCTCGTCGACCTGCACGCCCGATACGCTGAGTGTGGTTTGCGGATCCTGGCC
TTCCCGTGTAACCAGTTCGGGAAGCAG
GTGGGCTGCTGCGTCCCCGGGGCCCGCAGAGGCGGGTGGGTGGGGGTCGGGGTGGGCTCCAGCCTGGAGAGGGCCTGGGAGTGTGCAGGGGGC
CCGGACTGAGGGGGTGCCAGCCCCCGACTCACTCACACACCTTGGCCGCCACAGGAGCCAGGGAGTAACGAAGAGATCAAAGAGTTCGCCGCGGGCTACAACGTCAAATTCGATATGTTC
AGCAAGATCTGCGTGAACGGGGACGACGCCCACCCGCTGTGGAAGTGGATGAAGATCCAACCCAAGGGCAAGGGCATCCTGGGAAA
GTGCGTGACCTCTGGGGACAGTACGGCTGCTGGG
GTGGGGGTGGGGGGGCTGCTGGGATGCTCACACCTCCCTGGGGCAGAATGGCTCATGGCTCGGGGGGCGGTTGCGGGGAGGTGCTGGGACTCTCACATCGCGTGGCCTCCTGGGGGTAAG
ATGGCTCAGGGGGACATAGAGGGCTGTGGAGGCAGCCAGGGATGCCCACACCTTTGTGGCCTCCTGGGGACAGGATGGCTCGGGGGCCTGTGGGGGGCTGTTGGGACTCTCACACTGCAT
GGCCTCCTGGGGTAAGATGGCTCTGGGGGGGCTTGGGGGCACTGTGGCTGTGGAGGCAGCCGGGGAAGCTCACACCCTTGTGGCCTCCTGGAGACAGGACAGCTTGGGGACTGTGGGGGG
CTGCTGGGGACGCTCACGTCCATGTGCTTCTTTTCCAGTGCCATCAAGTGGAACTTCACCAAGGTAAGGGGGCTGTGGGGGGTAGGGGACCAGCTTCCCCTGGCCACAGCCGTGGCCCAG
ATGGGCAGCGGACAGGAAGGGCAGCCTCAGCCCCTTGCAGGGGTGGCCCCACAGTTTGGACACCGTCTCTCCACAGTTCCTCATCGACAAGAACGGCTGCGTGGTGAAGCGCTACGGACC
CATGGAGGAGCCCCTG
GTAGGTCCTCTCTAGGGAGCCCGCTTGAGGCTCGGGGGCTTGGGAGGTAGCTGCCCTAACCCAGCTTTCCTCCCCGACAGGTGATAGAGAAGGACCTGCCCCAC
TATTTCTAGCTCCACAAGTGTGTGGCCCCGCCCGAGCCCCTGCCCACGCCCTTGGAGCCTTCCACCGGCACTCATGA

Retrieve as FASTA  
CDS
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.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
ATGAGCCTCGGCCGCCTTTGCCGCCTACTGAAGCCGGCGCTGCTCTGTGGGGCTCTGGCCGCGCCTGGCCTGGCCGGGACCATGTGCGCGTCCCGGGACGACTGGCGCTGTGCGCGCTCC
ATGCACGAGTTTTCCGCCAAGGACATCGACGGGCACATGGTTAACCTGGACAAGTACCG
GGGCTTCGTGTGCATCGTCACCAACGTGGCCTCCCAGTGAGGCAAGACCGAAGTAAACTAC
ACTCAGCTCGTCGACCTGCACGCCCGATACGCTGAGTGTGGTTTGCGGATCCTGGCCTTCCCGTGTAACCAGTTCGGGAAGCAG
GAGCCAGGGAGTAACGAAGAGATCAAAGAGTTCGCC
GCGGGCTACAACGTCAAATTCGATATGTTCAGCAAGATCTGCGTGAACGGGGACGACGCCCACCCGCTGTGGAAGTGGATGAAGATCCAACCCAAGGGCAAGGGCATCCTGGGAAA
TGCC
ATCAAGTGGAACTTCACCAAG
TTTGGACACCGTCTCTCCACAGTTCCTCATCGACAAGAACGGCTGCGTGGTGAAGCGCTACGGACCCATGGAGGAGCCCCTGGTGATAGAGAAGGACCT
GCCCCACTATTTCTAGCTCCACAAGTGTGTGGCCCCGCCCGAGCCCCTGCCCACGCCCTTGGAGCCTTCCACCGGCACTCATGA

Retrieve as FASTA