Entry information : SpomBCP (DOT5 / nTPx)
Entry ID 4315
Creation 2007-01-25 (Filippo Passardi)
Last sequence changes 2007-01-25 (Filippo Passardi)
Sequence status complete
Reviewer Christophe Dunand
Last annotation changes 2008-09-22 (Christophe Dunand)
Peroxidase information: SpomBCP (DOT5 / nTPx)
Name (synonym) SpomBCP (DOT5 / nTPx)
Class Atypical 2-Cysteine peroxiredoxin (type BCP)    [Orthogroup: BCP001]
Taxonomy Eukaryota Fungi Ascomycota Schizosaccharomycetes Schizosaccharomycetaceae Schizosaccharomyces
Organism Schizosaccharomyces pombe    [TaxId: 4896 ]
Cellular localisation Nucleus
Tissue type N/D
Inducer N/D
Repressor N/D
Best BLASTp hits
Perox score E-value SpomBCP
start..stop
S start..stop
PplPrxQ02 137 4e-41 44..179 80..212
CnPrxQ_JEC21 134 1e-40 46..192 19..164
CnPrxQ_grubiiH99 133 3e-40 45..192 18..164
LbiPrxQ02 133 2e-39 2..179 13..211
Literature and cross-references SpomBCP (DOT5 / nTPx)
Literature REFERENCE 1 Wood V. et al. The genome sequence of Schizosaccharomyces pombe. Nature 415:871-880(2002).

REFERENCE 2 Singer MS et al., Genetics (1998), 150:613-632.
Protein ref. UniProtKB:   O94561
DNA ref. GenBank:   CU329671 (283938..284525)
Protein sequence: SpomBCP (DOT5 / nTPx)
Sequence Properties
first value : protein
second value (mature protein)
Length (aa):   %s   195
PWM (Da):   %s   21054.06  
PI (pH):   %s   9.12
Sequence
Send to BLAST
Send to Peroxiscan
.........1 .........2 .........3 .........4 .........5 .........6 .........7 .........8 .........9 .........0 .........1 .........2
MDAPRRSSRL AAKIANVLDS KGTIIPEAAP VMLKKPAKDE SVDSTIQVGD VIPDITLPDE DGTSIRLRDI TANKGLVIFA YPKASTPGCT KQGCGFRDNY PKIQASDYEV LGLSFDTSKA 
QKAFKDKQNF PYHLLSDPKG ELIKKLGAEK PGGGKLFRSH WIFEKGTGKC IVKEIDISPL VSVDKAFAVI TDSEP 

Retrieve as FASTA  
Remarks Genomic DNA (chromo II, . Strain="ATCC 38366/972". Protein probably involved in telomere de-repression (Izawa S. et al., Appl Microbiol Biotechnol, 2004, 64:120-124). Possesses thioredoxin peroxidase activity. The protein bears a nuclear localisation signal in its N-terminus (Park SG et al, J Biol Chem, 2000, 275:5723-5732).