Entry information : HsPrxV (PRDX5)
Entry ID 4448
Creation 2007-01-22 (Nicolas Rouhier)
Last sequence changes 2010-12-03 (Myriam Duval (Scipio))
Sequence status complete
Reviewer Christophe Dunand
Last annotation changes 2010-12-03 (Myriam Duval (Scipio))
Peroxidase information: HsPrxV (PRDX5)
Name (synonym) HsPrxV (PRDX5)
Class Atypical 2-Cysteine peroxiredoxin (type V)    [Orthogroup: PrxV001]
Taxonomy Eukaryota Metazoa Chordata Mammalia Hominidae Homo
Organism Homo sapiens (human)    [TaxId: 9606 ]
Cellular localisation Mitochondria
Tissue type N/D
Inducer N/D
Repressor N/D
Best BLASTp hits
Perox score E-value HsPrxV
start..stop
S start..stop
PtroPrxV 421 1e-152 1..214 1..214
GgoPrxV 417 3e-151 1..214 1..214
PpyPrxV 389 4e-140 1..214 1..216
MmulPrxV 388 6e-140 1..214 1..215
Gene structure Fichier Exons
ExonStart..EndSize ExonStart..EndSize ExonStart..EndSize ExonStart..EndSize
N° 1 64085688..64085858 171 N° 2 64087206..64087340 135 N° 3 64088133..64088264 132 N° 4 64088337..64088375 39
N° 5 64088479..64088540 62 N° 6 64089058..64089163 106  
join(64085688..64085858,64087206..64087340,64088133..64088264,64088337..64088375 ,64088479..64088540,64089058..64089163)


exon

Literature and cross-references HsPrxV (PRDX5)
Literature Seo M.S., Kang S.W., Kim K., Baines I.C., Lee T.H., Rhee S.G. Identification of a new type of mammalian peroxiredoxin that forms an intramolecular disulfide as a reaction intermediate. J. Biol. Chem. 275:20346-20354(2000).
Protein ref. UniProtKB:   P30044   Q14CK0
DNA ref. GenBank:   NC_000011.9 (64085688..64089163)
Cluster/Prediction ref. UniGene:   Hs.502823
Protein sequence: HsPrxV (PRDX5)
Sequence Properties
first value : protein
second value (mature protein)
Length (aa):   %s   214
PWM (Da):   %s   21959.47  
PI (pH):   %s   8.97
Sequence
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Send to Peroxiscan
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
MGLAGVCALRRSAGYILVGGAGGQSAAAAARRYSEGEWASGGVRSFSRAAAAMAPIKVGDAIPAVEVFEGEPGNKVNLAELFKGKKGVLFGVPGAFTPGCSKTHLPGFVEQAEALKAKGVQVVACLSVNDAFVTGEWGRAHKAEGKVRLLADPTGAFGKETDLLLDDSLVSIFGNRRLKRFSMVVQDGIVKALNVEPDGTGLTCSLAPNIISQL

Retrieve as FASTA  
Remarks Complete sequence from genomic (Chromo 11, 5 introns), 21 cDNA and 529 ESTs.
DNA
Send to BLAST
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
ATGGGACTAGCTGGCGTGTGCGCCCTGAGACGCTCAGCGGGCTATATACTCGTCGGTGGGGCCGGCGGTCAGTCTGCGGCAGCGGCAGCAAGACGGTACAGTGAAGGAGAGTGGGCGTCT
GGCGGGGTCCGCAGTTTCAGCAGAGCCGCTGCAGCCATGGCCCCAATCAAG
GTGACCGCTGGCCCGGCCGGGCCTGACATCCCCCACTACCCCCATGGCAATCCCCGTCCCGCTAGTCTG
AGAGTATCGCTTTATTTCCTGCCTGCCAGACCCCTCCCCTCCGCCCGCCCGGCTCATCCCTTCAGAAGGCCCTCGTGGCTGCCCACCTTTCTCGCCAATCGTGGGGGCCTCACCTCCCGG
GACAGTCCCGAGGCATTGTGTTTTTTGTTTTTTGTTTTTTTTTGAGACGGAGTCTTTCTGTGTCGCCCAGGCTGGAGTGCAGTGACGCAATCTCTGCTCACTGCAGCCTCCGCCTCCCGG
GTTCAAGCGATTCTACTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGATGCGAGCCACCACGCCCAGCTATTGTATTTTTAGTAGAGACGGGATTTCACCCCGTTGTTCAGATTGGTCT
CGAACTCCTGACCTCAGGTGAACCCCCCCCGCCCCCCCCCGCCTCGGCTTCCCGAAGTGCTAGGATTACAGGTGTGAGACACCACTCCCGGCCTGATTTCCCCTATCTTCTGAAACAGCT
GTCCCTTAGCGCCCCCGCGGGGGCTTACCCCATCCCACTCCATGACCTCCCCTCCCCCCATGGCGAATTCCCACCTTTCTGTCTTTCACTCACTTCCTGGAACCGTCCCCAGGGCCTTGG
ACCTTCCCCCTTCTCCTCCCAAACCTTGTGAGACCCCATTCCCTTTCTACTTCATCCTGCTCTCAACCTTTGGGCTCCTCAGAGGCCCTCACCTCTGACTCTCTCTCCCTACCCACTCTG
GTCCCATGAAGCCCTCAAGTACTCTGGGGATGGATCCTTCCCCCTTCAAAAGATTCCTTCTTTTGTTCTACACCTCCTGGGTGTAGGGGCCTGGACACCCTCCCCCAACGTTCCACCTGC
CGCTGCCCTTCCTCTTCCTCCTCCTGAGGGTGGGACCCTCAGACCTGGCCAAGATCCTCTCCCTCCATGTTGTCAGGGACTCCTCCTCACCCCCAAATACAGCCCTCTAGCCCCTGTCCA
TTTTATTCCACTCCTTTCCTGTAACCTAGACAGCATGTTATGCAACCCTTTGCGACACATGGGGAAACCTTCCCTCCCTTTCTCTGTTGTCACCAATGGCCCCTTAAGAGGAGCAGGGCC
ACCTTGAAACTTGGAGGATATGGGGTAACCCAGTGGGAGCGGGCAGGGAGGGCCCTTGGAAACTGACAGGGCTGGAGTATCCTGCTGGGTTTCAGCCCCGGTTCCTGCAGGCACAGCTGC
CAGGCTCTCTGTTCACCTTCCTGCCTCTGGTTTGCCCCGGCTCCCTCACCCCCCTTACCCTGGAGTCCTTCCTTCTAGGTGGGAGATGCCATCCCAGCAGTGGAGGTGTTTGAAGGGGAG
CCAGGGAACAAGGTGAACCTGGCAGAGCTGTTCAAGGGCAAGAAGGGTGTGCTGTTTGGAGTTCCTGGGGCCTTCACCCCTGGATGTTCCAAG
GTGAGGCCCTTCCCCTTCTGAAGATCA
GGACCTGGGATCTTTTGTGTTGCTCTTAAGTCCTCCACATAGTCCTGATAGGACTCCTAAAAAGCATTTCAGTGCCATCACAAAACAAGTAGAGCTGGGTAGAGCTGGGCGCGGTGGCTC
ACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGTGGATCACGAGGTCAGGAGTTCAAAACCAGTCTGGCCAAGATGGTGAAACCCTGTCTCTACTAAAAATGCAAAAAAATCAGC
CGGACATGGTGGCGGGCGCCTGTAATCCCAGGTACTGGGGAGGCTGAGGCAGAGAATTGCTTGAACCCAGGAGGCGTAGGTTGCAGTGAGTGGAGATCGTGCCTCTGCAGTCCAGCCTGG
GTGAAAGAGCGAGACTCCGTCTCAAAATGAAAAAAAAAAAAAAGAAAACAAGTAGAGACTGCAAAAAGGGAACAGTACCAGGAATGTTGGAGAAAAACATACTACAATTAAATCCAACAC
CCCTGTTGGTCCTGCTAAATGACAGGCACTGTGGAAGGTGCTTGGGACTCAGATAAATAAGACATAGATCTGCCCATGGAAAGTTCACGTCTGGACCATAAGGCATTAGGTTTCATTCTG
AGCTTCCTAGTGGCCAAGGCAAAAAGGAAATAGAATGGTTTAGACAGCTCTCATTGTCTGATCAAAGGTGTTGAGGCAGAGCACTGAGGAGGGCCTGGAGATAAAGGGTGGGCTGGGGGT
CAGATGCAGTTATCCCTTTGCCGACCCTTTGTTCCCCTTCCTCAGACACACCTGCCAGGGTTTGTGGAGCAGGCTGAGGCTCTGAAGGCCAAGGGAGTCCAGGTGGTGGCCTGTCTGAGT
GTTAATGATGCCTTTGTGACTGGCGAGTGGGGCCGAGCCCACAAGGCGGAAGGCAAG
GTGAGGTGAGGGGCCTGCAGGGAGTCAGGACCAGGTAGGATATTCTTCTTGTGACCTTTACTT
TCTCTGCAGGTTCGGCTCCTGGCTGATCCCACTGGGGCCTTTGGGAAGGTGAGTGTTCCCCTGACCGCCACAGGGACATGGCAGTGCGGGGAGCAGTGGGGGCCCTTAGCCTCTTCAAGG
ATTTCTGACACTTTTCTCTGTCTCTTCTTAGGAGACAGACTTATTACTAGATGATTCGCTGGTGTCCATCTTTGGGAATCGACGTCTCAAGAGGTAAAAGTGGAGAGTCCTCTGTGGAGA
GAGTCCTCTGTGGGAGAGAGTCCTCTGTGGGAGAGAGTCCTCTGTGGAGAGGGTCCTCTGTGGGAAGAGTCGTCTGTGGGGGAGAGTCCTCTGTGTGGGAGAGTCGTCTGTGGGGAGAGT
CCTGTGTGGGGAGAGTCCTCTGTGGAGAGAGTCCTCTGTGGGGGAGAGTCCTGTGTGGGGGAGAGTCCTCTGTGGGGAGAGTCCTCTGTGTGGAGAGAGTCCTGTGTGGGAGAGAGTCCT
GTGTGGGGAGAGTCTTCTGTAGGGGAGAGTCCTCTGGGGAGAGAGTCCTGTGTGGGGGAGAGTTCTCTGTGGGGAGAGTCCTCTGTGTGGAGAGAGTCCTGTGTGGTGGTGAGTCCTCTG
TGGGGGAGAGTCCTCTGTGGGGGGAGTCCTCTCTGGAGTTCTCTTGGGCCCCTGGCTGTTCACTGCCTGTCTCCATGCCCAGCCTCCAAGCCCAGGCTGATGCAGCTGGCTGGGCCCCTC
TTTCCGGCAGGTTCTCCATGGTGGTACAGGATGGCATAGTGAAGGCCCTGAATGTGGAACCAGATGGCACAGGCCTCACCTGCAGCCTGGCACCCAATATCATCTCACAGCTCTGA

Retrieve as FASTA  
CDS
Send to BLAST
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
ATGGGACTAGCTGGCGTGTGCGCCCTGAGACGCTCAGCGGGCTATATACTCGTCGGTGGGGCCGGCGGTCAGTCTGCGGCAGCGGCAGCAAGACGGTACAGTGAAGGAGAGTGGGCGTCT
GGCGGGGTCCGCAGTTTCAGCAGAGCCGCTGCAGCCATGGCCCCAATCAAG
GTGGGAGATGCCATCCCAGCAGTGGAGGTGTTTGAAGGGGAGCCAGGGAACAAGGTGAACCTGGCAGAG
CTGTTCAAGGGCAAGAAGGGTGTGCTGTTTGGAGTTCCTGGGGCCTTCACCCCTGGATGTTCCAAG
ACACACCTGCCAGGGTTTGTGGAGCAGGCTGAGGCTCTGAAGGCCAAGGGAGTC
CAGGTGGTGGCCTGTCTGAGTGTTAATGATGCCTTTGTGACTGGCGAGTGGGGCCGAGCCCACAAGGCGGAAGGCAAG
GTTCGGCTCCTGGCTGATCCCACTGGGGCCTTTGGGAAGGAG
ACAGACTTATTACTAGATGATTCGCTGGTGTCCATCTTTGGGAATCGACGTCTCAAGAG
GTTCTCCATGGTGGTACAGGATGGCATAGTGAAGGCCCTGAATGTGGAACCAGATGGCACA
GGCCTCACCTGCAGCCTGGCACCCAATATCATCTCACAGCTCTGA

Retrieve as FASTA