Entry information : HsPrxV (PRDX5)
Entry ID 4448
Creation 2007-01-22 (Nicolas Rouhier)
Last sequence changes 2010-12-03 (Myriam Duval (Scipio))
Sequence status complete
Reviewer Christophe Dunand
Last annotation changes 2010-12-03 (Myriam Duval (Scipio))
Peroxidase information: HsPrxV (PRDX5)
Name (synonym) HsPrxV (PRDX5)
Class Atypical 2-Cysteine peroxiredoxin (type V)    [Orthogroup: PrxV001]
Taxonomy Eukaryota Metazoa Chordata Mammalia Hominidae Homo
Organism Homo sapiens (human)    [TaxId: 9606 ]
Cellular localisation Mitochondria
Tissue type N/D
Inducer N/D
Repressor N/D
Best BLASTp hits
Perox score E-value HsPrxV
start..stop
S start..stop
PtroPrxV 421 1e-152 1..214 1..214
GgoPrxV 417 3e-151 1..214 1..214
PpyPrxV 389 4e-140 1..214 1..216
MmulPrxV 388 6e-140 1..214 1..215
Gene structure Fichier Exons
ExonStart..EndSize ExonStart..EndSize ExonStart..EndSize ExonStart..EndSize
N° 1 64085688..64085858 171 N° 2 64087206..64087340 135 N° 3 64088133..64088264 132 N° 4 64088337..64088375 39
N° 5 64088479..64088540 62 N° 6 64089058..64089163 106  
join(64085688..64085858,64087206..64087340,64088133..64088264,64088337..64088375 ,64088479..64088540,64089058..64089163)


exon

Literature and cross-references HsPrxV (PRDX5)
Literature Seo M.S., Kang S.W., Kim K., Baines I.C., Lee T.H., Rhee S.G. Identification of a new type of mammalian peroxiredoxin that forms an intramolecular disulfide as a reaction intermediate. J. Biol. Chem. 275:20346-20354(2000).
Protein ref. UniProtKB:   P30044   Q14CK0
DNA ref. GenBank:   NC_000011.9 (64085688..64089163)
Cluster/Prediction ref. UniGene:   Hs.502823
Protein sequence: HsPrxV (PRDX5)
Sequence Properties
first value : protein
second value (mature protein)
Length (aa): %sProtein length in amino acid 214
PWM (Da): %sMolecular Weight of protein
Protein Mw is calculated by the addition of average isotopic masses
of amino acids in the protein and the average isotopic mass of one water molecule.
Molecular weight values are given in Dalton (Da).
21959.47  
PI (pH): %sIso electric point of protein
Calculation done with EMBOSS parameters.
Please see Dataset for pKi calculation for more information
8.97
Sequence
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Send to Peroxiscan
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
MGLAGVCALRRSAGYILVGGAGGQSAAAAARRYSEGEWASGGVRSFSRAAAAMAPIKVGDAIPAVEVFEGEPGNKVNLAELFKGKKGVLFGVPGAFTPGCSKTHLPGFVEQAEALKAKGVQVVACLSVNDAFVTGEWGRAHKAEGKVRLLADPTGAFGKETDLLLDDSLVSIFGNRRLKRFSMVVQDGIVKALNVEPDGTGLTCSLAPNIISQL

Retrieve as FASTA  
Remarks Complete sequence from genomic (Chromo 11, 5 introns), 21 cDNA and 529 ESTs.
DNA
Send to BLAST
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
ATGGGACTAGCTGGCGTGTGCGCCCTGAGACGCTCAGCGGGCTATATACTCGTCGGTGGGGCCGGCGGTCAGTCTGCGGCAGCGGCAGCAAGACGGTACAGTGAAGGAGAGTGGGCGTCT
GGCGGGGTCCGCAGTTTCAGCAGAGCCGCTGCAGCCATGGCCCCAATCAAG
GTGACCGCTGGCCCGGCCGGGCCTGACATCCCCCACTACCCCCATGGCAATCCCCGTCCCGCTAGTCTG
AGAGTATCGCTTTATTTCCTGCCTGCCAGACCCCTCCCCTCCGCCCGCCCGGCTCATCCCTTCAGAAGGCCCTCGTGGCTGCCCACCTTTCTCGCCAATCGTGGGGGCCTCACCTCCCGG
GACAGTCCCGAGGCATTGTGTTTTTTGTTTTTTGTTTTTTTTTGAGACGGAGTCTTTCTGTGTCGCCCAGGCTGGAGTGCAGTGACGCAATCTCTGCTCACTGCAGCCTCCGCCTCCCGG
GTTCAAGCGATTCTACTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGATGCGAGCCACCACGCCCAGCTATTGTATTTTTAGTAGAGACGGGATTTCACCCCGTTGTTCAGATTGGTCT
CGAACTCCTGACCTCAGGTGAACCCCCCCCGCCCCCCCCCGCCTCGGCTTCCCGAAGTGCTAGGATTACAGGTGTGAGACACCACTCCCGGCCTGATTTCCCCTATCTTCTGAAACAGCT
GTCCCTTAGCGCCCCCGCGGGGGCTTACCCCATCCCACTCCATGACCTCCCCTCCCCCCATGGCGAATTCCCACCTTTCTGTCTTTCACTCACTTCCTGGAACCGTCCCCAGGGCCTTGG
ACCTTCCCCCTTCTCCTCCCAAACCTTGTGAGACCCCATTCCCTTTCTACTTCATCCTGCTCTCAACCTTTGGGCTCCTCAGAGGCCCTCACCTCTGACTCTCTCTCCCTACCCACTCTG
GTCCCATGAAGCCCTCAAGTACTCTGGGGATGGATCCTTCCCCCTTCAAAAGATTCCTTCTTTTGTTCTACACCTCCTGGGTGTAGGGGCCTGGACACCCTCCCCCAACGTTCCACCTGC
CGCTGCCCTTCCTCTTCCTCCTCCTGAGGGTGGGACCCTCAGACCTGGCCAAGATCCTCTCCCTCCATGTTGTCAGGGACTCCTCCTCACCCCCAAATACAGCCCTCTAGCCCCTGTCCA
TTTTATTCCACTCCTTTCCTGTAACCTAGACAGCATGTTATGCAACCCTTTGCGACACATGGGGAAACCTTCCCTCCCTTTCTCTGTTGTCACCAATGGCCCCTTAAGAGGAGCAGGGCC
ACCTTGAAACTTGGAGGATATGGGGTAACCCAGTGGGAGCGGGCAGGGAGGGCCCTTGGAAACTGACAGGGCTGGAGTATCCTGCTGGGTTTCAGCCCCGGTTCCTGCAGGCACAGCTGC
CAGGCTCTCTGTTCACCTTCCTGCCTCTGGTTTGCCCCGGCTCCCTCACCCCCCTTACCCTGGAGTCCTTCCTTCTAGGTGGGAGATGCCATCCCAGCAGTGGAGGTGTTTGAAGGGGAG
CCAGGGAACAAGGTGAACCTGGCAGAGCTGTTCAAGGGCAAGAAGGGTGTGCTGTTTGGAGTTCCTGGGGCCTTCACCCCTGGATGTTCCAAG
GTGAGGCCCTTCCCCTTCTGAAGATCA
GGACCTGGGATCTTTTGTGTTGCTCTTAAGTCCTCCACATAGTCCTGATAGGACTCCTAAAAAGCATTTCAGTGCCATCACAAAACAAGTAGAGCTGGGTAGAGCTGGGCGCGGTGGCTC
ACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGTGGATCACGAGGTCAGGAGTTCAAAACCAGTCTGGCCAAGATGGTGAAACCCTGTCTCTACTAAAAATGCAAAAAAATCAGC
CGGACATGGTGGCGGGCGCCTGTAATCCCAGGTACTGGGGAGGCTGAGGCAGAGAATTGCTTGAACCCAGGAGGCGTAGGTTGCAGTGAGTGGAGATCGTGCCTCTGCAGTCCAGCCTGG
GTGAAAGAGCGAGACTCCGTCTCAAAATGAAAAAAAAAAAAAAGAAAACAAGTAGAGACTGCAAAAAGGGAACAGTACCAGGAATGTTGGAGAAAAACATACTACAATTAAATCCAACAC
CCCTGTTGGTCCTGCTAAATGACAGGCACTGTGGAAGGTGCTTGGGACTCAGATAAATAAGACATAGATCTGCCCATGGAAAGTTCACGTCTGGACCATAAGGCATTAGGTTTCATTCTG
AGCTTCCTAGTGGCCAAGGCAAAAAGGAAATAGAATGGTTTAGACAGCTCTCATTGTCTGATCAAAGGTGTTGAGGCAGAGCACTGAGGAGGGCCTGGAGATAAAGGGTGGGCTGGGGGT
CAGATGCAGTTATCCCTTTGCCGACCCTTTGTTCCCCTTCCTCAGACACACCTGCCAGGGTTTGTGGAGCAGGCTGAGGCTCTGAAGGCCAAGGGAGTCCAGGTGGTGGCCTGTCTGAGT
GTTAATGATGCCTTTGTGACTGGCGAGTGGGGCCGAGCCCACAAGGCGGAAGGCAAG
GTGAGGTGAGGGGCCTGCAGGGAGTCAGGACCAGGTAGGATATTCTTCTTGTGACCTTTACTT
TCTCTGCAGGTTCGGCTCCTGGCTGATCCCACTGGGGCCTTTGGGAAGGTGAGTGTTCCCCTGACCGCCACAGGGACATGGCAGTGCGGGGAGCAGTGGGGGCCCTTAGCCTCTTCAAGG
ATTTCTGACACTTTTCTCTGTCTCTTCTTAGGAGACAGACTTATTACTAGATGATTCGCTGGTGTCCATCTTTGGGAATCGACGTCTCAAGAGGTAAAAGTGGAGAGTCCTCTGTGGAGA
GAGTCCTCTGTGGGAGAGAGTCCTCTGTGGGAGAGAGTCCTCTGTGGAGAGGGTCCTCTGTGGGAAGAGTCGTCTGTGGGGGAGAGTCCTCTGTGTGGGAGAGTCGTCTGTGGGGAGAGT
CCTGTGTGGGGAGAGTCCTCTGTGGAGAGAGTCCTCTGTGGGGGAGAGTCCTGTGTGGGGGAGAGTCCTCTGTGGGGAGAGTCCTCTGTGTGGAGAGAGTCCTGTGTGGGAGAGAGTCCT
GTGTGGGGAGAGTCTTCTGTAGGGGAGAGTCCTCTGGGGAGAGAGTCCTGTGTGGGGGAGAGTTCTCTGTGGGGAGAGTCCTCTGTGTGGAGAGAGTCCTGTGTGGTGGTGAGTCCTCTG
TGGGGGAGAGTCCTCTGTGGGGGGAGTCCTCTCTGGAGTTCTCTTGGGCCCCTGGCTGTTCACTGCCTGTCTCCATGCCCAGCCTCCAAGCCCAGGCTGATGCAGCTGGCTGGGCCCCTC
TTTCCGGCAGGTTCTCCATGGTGGTACAGGATGGCATAGTGAAGGCCCTGAATGTGGAACCAGATGGCACAGGCCTCACCTGCAGCCTGGCACCCAATATCATCTCACAGCTCTGA

Retrieve as FASTA  
CDS
Send to BLAST
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
ATGGGACTAGCTGGCGTGTGCGCCCTGAGACGCTCAGCGGGCTATATACTCGTCGGTGGGGCCGGCGGTCAGTCTGCGGCAGCGGCAGCAAGACGGTACAGTGAAGGAGAGTGGGCGTCT
GGCGGGGTCCGCAGTTTCAGCAGAGCCGCTGCAGCCATGGCCCCAATCAAG
GTGGGAGATGCCATCCCAGCAGTGGAGGTGTTTGAAGGGGAGCCAGGGAACAAGGTGAACCTGGCAGAG
CTGTTCAAGGGCAAGAAGGGTGTGCTGTTTGGAGTTCCTGGGGCCTTCACCCCTGGATGTTCCAAG
ACACACCTGCCAGGGTTTGTGGAGCAGGCTGAGGCTCTGAAGGCCAAGGGAGTC
CAGGTGGTGGCCTGTCTGAGTGTTAATGATGCCTTTGTGACTGGCGAGTGGGGCCGAGCCCACAAGGCGGAAGGCAAG
GTTCGGCTCCTGGCTGATCCCACTGGGGCCTTTGGGAAGGAG
ACAGACTTATTACTAGATGATTCGCTGGTGTCCATCTTTGGGAATCGACGTCTCAAGAG
GTTCTCCATGGTGGTACAGGATGGCATAGTGAAGGCCCTGAATGTGGAACCAGATGGCACA
GGCCTCACCTGCAGCCTGGCACCCAATATCATCTCACAGCTCTGA

Retrieve as FASTA