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Entry information : TcrAPx-CcP01
Entry ID 2308
Creation 2006-12-21 (Christophe Dunand)
Last sequence changes 2012-06-19 (Christophe Dunand)
Sequence status complete
Reviewer Not yet reviewed
Last annotation changes 2012-06-19 (Christophe Dunand)
Peroxidase information: TcrAPx-CcP01
Name TcrAPx-CcP01
Class Hybrid Ascorbate-Cytochrome C peroxidase    [Orthogroup: APx-CcP001]
Taxonomy Eukaryota Trypanosomatidae Trypanosoma
Organism Trypanosoma cruzi    [TaxId: 5693 ]
Cellular localisation Endoplasmic reticulum
Tissue type N/D
Inducer N/D
Repressor N/D
Best BLASTp hits
Perox score E-value TcrAPx-CcP01
start..stop		 S start..stop
TcrAPx-CcP02 676 0 1..328 1..328
LmexAPx-CcP01 405 3.72e-143 18..325 3..300
LmAPx-CcP 399 8.89e-141 17..325 2..300
LbraAPx-CcP 399 1.54e-140 32..325 12..302
Literature and cross-references TcrAPx-CcP01
Literature Wilkinson,S.R., Obado,S.O., Mauricio,I.L. and Kelly,J.M. Trypanosoma cruzi expresses a plant-like ascorbate-dependent hemoperoxidase localized to the endoplasmic reticulum Proc. Natl. Acad. Sci. U.S.A. 99 (21), 13453-13458 (2002)
Protein ref. UniProtKB:   Q8I1N3
DNA ref. GenBank:   AAHK01002212.1 (5279..6262)
Protein sequence: TcrAPx-CcP01
Sequence Properties
first value : protein
second value (mature protein)
Length (aa):   %s   328
PWM (Da):   %s   36349.75  
PI (pH):   %s   7.44
Sequence
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*.........1 .........2 .........3 .........4 .........5 .........6 .........7 .........8 .........9 .........0 .........1 .........2
MAFCFGSFFS KYASSKSGSQ ARYRFLHSSA KIAAGATGAL LLGGATVALC YFPSGRKVTE APPFDVNSLR RDIEEILSED MSKGPLFVRL AWHEAGSWDC RKKDGSPNSA SMRFHPECSY  AGNKGLDKGR NALESLKKKY PKISYADLWS FAAVVSIEAM GGPEIPWRWG RVDAKDGSVC GPDGRLPDAS RMQDHVRDVF SRLGFNDEET VALIGAHTCG ECHLENTGYV GPWTHDKYGF 
DNSFFTELFG NEWMLNPNVK KMQFMDKTTN RLMMLPADVS ILLDDKYRSI AKKYADDNDY FCNAFSKAYQ KLLEVGTTDL KSLPAESK 

Retrieve as FASTA  
Remarks Complete sequence from 2 ESTs and 1 genomic (no intron). Annotated as Ascorbate peroxidase (unspecific ascorbate peroxidase activity?), but the sequence contains some CcP motifs.
DNA ►
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.........1 .........2 .........3 .........4 .........5 .........6 .........7 .........8 .........9 .........0 .........1 .........2
ATGGCTTTTT GTTTTGGTTC ATTCTTTTCG AAGTACGCTT CATCCAAATC AGGTTCTCAG GCAAGGTACC GTTTTCTTCA TTCCTCGGCT AAAATTGCTG CCGGCGCCAC CGGTGCATTG  CTTTTGGGCG GTGCCACCGT GGCCTTATGT TATTTTCCCT CGGGACGAAA GGTCACGGAG GCACCGCCGT TTGATGTGAA CTCACTAAGA AGGGACATTG AAGAAATACT CTCCGAGGAT  ATGTCTAAAG GGCCTCTTTT TGTGCGACTC GCGTGGCACG AGGCTGGATC ATGGGACTGC CGGAAAAAGG ATGGGAGTCC TAATTCCGCT TCGATGCGAT TTCACCCAGA GTGCAGCTAT  GCCGGCAACA AAGGGCTTGA TAAAGGACGA AATGCGCTGG AATCGCTCAA GAAAAAGTAC CCGAAAATTT CATACGCCGA TTTATGGTCC TTCGCAGCGG TGGTGTCGAT TGAGGCGATG  GGTGGCCCGG AGATTCCGTG GCGGTGGGGG CGCGTGGATG CAAAGGACGG CAGCGTTTGT GGCCCCGATG GGCGTCTCCC TGACGCGTCC AGGATGCAGG ATCACGTGCG GGATGTCTTT  TCACGTCTTG GCTTTAATGA TGAAGAAACT GTTGCCTTGA TCGGGGCCCA CACATGTGGT GAGTGCCATC TGGAGAACAC GGGCTACGTG GGTCCGTGGA CGCACGACAA GTACGGCTTT  GACAACTCCT TTTTTACGGA GCTTTTTGGC AACGAGTGGA TGCTGAACCC CAATGTGAAG AAAATGCAGT TCATGGACAA AACCACTAAC CGCCTTATGA TGCTGCCCGC TGATGTTTCC  ATTCTTCTGG ACGACAAGTA TCGTTCCATC GCGAAGAAGT ACGCGGACGA CAATGATTAT TTTTGCAACG CCTTCAGCAA GGCTTATCAG AAGTTGCTTG AGGTTGGAAC CACCGATCTC 
AAGTCTCTCC CAGCAGAGTC AAAATAG 

Retrieve as FASTA  
CDS►
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.........1 .........2 .........3 .........4 .........5 .........6 .........7 .........8 .........9 .........0 .........1 .........2
ATGGCTTTTT GTTTTGGTTC ATTCTTTTCG AAGTACGCTT CATCCAAATC AGGTTCTCAG GCAAGGTACC GTTTTCTTCA TTCCTCGGCT AAAATTGCTG CCGGCGCCAC CGGTGCATTG  CTTTTGGGCG GTGCCACCGT GGCCTTATGT TATTTTCCCT CGGGACGAAA GGTCACGGAG GCACCGCCGT TTGATGTGAA CTCACTAAGA AGGGACATTG AAGAAATACT CTCCGAGGAT  ATGTCTAAAG GGCCTCTTTT TGTGCGACTC GCGTGGCACG AGGCTGGATC ATGGGACTGC CGGAAAAAGG ATGGGAGTCC TAATTCCGCT TCGATGCGAT TTCACCCAGA GTGCAGCTAT  GCCGGCAACA AAGGGCTTGA TAAAGGACGA AATGCGCTGG AATCGCTCAA GAAAAAGTAC CCGAAAATTT CATACGCCGA TTTATGGTCC TTCGCAGCGG TGGTGTCGAT TGAGGCGATG  GGTGGCCCGG AGATTCCGTG GCGGTGGGGG CGCGTGGATG CAAAGGACGG CAGCGTTTGT GGCCCCGATG GGCGTCTCCC TGACGCGTCC AGGATGCAGG ATCACGTGCG GGATGTCTTT  TCACGTCTTG GCTTTAATGA TGAAGAAACT GTTGCCTTGA TCGGGGCCCA CACATGTGGT GAGTGCCATC TGGAGAACAC GGGCTACGTG GGTCCGTGGA CGCACGACAA GTACGGCTTT  GACAACTCCT TTTTTACGGA GCTTTTTGGC AACGAGTGGA TGCTGAACCC CAATGTGAAG AAAATGCAGT TCATGGACAA AACCACTAAC CGCCTTATGA TGCTGCCCGC TGATGTTTCC  ATTCTTCTGG ACGACAAGTA TCGTTCCATC GCGAAGAAGT ACGCGGACGA CAATGATTAT TTTTGCAACG CCTTCAGCAA GGCTTATCAG AAGTTGCTTG AGGTTGGAAC CACCGATCTC 
AAGTCTCTCC CAGCAGAGTC AAAATAG 

Retrieve as FASTA