The peroxidases and oxidases database
Entry information : HsDuOx01 (DUOX1 / LNOX1 / THOX1)
Entry ID 3339
Creation 2006-07-26 (Christophe Dunand)
Last sequence changes 2006-07-26 (Christophe Dunand)
Sequence status complete
Reviewer Catherine Mathe
Last annotation changes 2015-12-10 (Catherine Mathe)
Peroxidase information: HsDuOx01 (DUOX1 / LNOX1 / THOX1)
Name (synonym) HsDuOx01 (DUOX1 / LNOX1 / THOX1)
Class Dual oxidase    [Orthogroup: DuOx001]
Taxonomy Eukaryota Metazoa Chordata Mammalia Hominidae Homo
Organism Homo sapiens (human)    [TaxId: 9606 ]
Cellular localisation N/D
Tissue type N/D
Inducer N/D
Repressor N/D
Best BLASTp hits
Perox score E-value HsDuOx01
start..stop		 S start..stop
PtroDuOx01 3180 0 1..1551 1..1551
MmulDuOx01 3034 0 1..1551 1..1551
MmDuOx01 2898 0 1..1551 1..1551
CfaDuOx01 2896 0 1..1551 1..1551
Gene structure Fichier Exons►
ExonStart..EndSize ExonStart..EndSize ExonStart..EndSize ExonStart..EndSize
N° 1 45424165..45424222 58 N° 2 45426062..45426145 84 N° 3 45426343..45426507 165 N° 4 45427302..45427489 188
N° 5 45427672..45427873 202 N° 6 45427980..45428146 167 N° 7 45428548..45428608 61 N° 8 45428727..45428823 97
N° 9 45430122..45430212 91 N° 10 45431264..45431366 103 N° 11 45431625..45431797 173 N° 12 45433093..45433268 176
N° 13 45433490..45433608 119 N° 14 45434173..45434310 138 N° 15 45435388..45435501 114 N° 16 45436234..45436433 200
N° 17 45437093..45437278 186 N° 18 45439631..45439856 226 N° 19 45440102..45440195 94 N° 20 45440470..45440645 176
N° 21 45442830..45442899 70 N° 22 45443321..45443446 126 N° 23 45444072..45444250 179 N° 24 45444484..45444714 231
N° 25 45445578..45445677 100 N° 26 45446149..45446198 50 N° 27 45448000..45448127 128 N° 28 45453035..45453188 154
N° 29 45453936..45454168 233 N° 30 45454417..45454575 159 N° 31 45455730..45455885 156 N° 32 45455988..45456116 129
N° 33 45456977..45457099 123  
join(45424165..45424222,45426062..45426145,45426343..45426507,45427302..45427489 ,45427672..45427873,45427980..45428146,45428548..45428608,45428727..45428823,454 30122..45430212,45431264..45431366,45431625..45431797,45433093..45433268,4543349 0..45433608,45434173..45434310,45435388..45435501,45436234..45436433,45437093..4 5437278,45439631..45439856,45440102..45440195,45440470..45440645,45442830..45442 899,45443321..45443446,45444072..45444250,45444484..45444714,45445578..45445677, 45446149..45446198,45448000..45448127,45453035..45453188,45453936..45454168,4545 4417..45454575,45455730..45455885,45455988..45456116,45456977..45457099)


exon

Literature and cross-references HsDuOx01 (DUOX1 / LNOX1 / THOX1)
Literature De Deken X., Wang D., Many M.-C., Costagliola S., Libert F., Vassart G., Dumont J.E., Miot F. Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family. J. Biol. Chem. 275:23227-23233(2000).
Protein ref. UniProtKB:   Q9NRD9
DNA ref. GenBank:   NC_000015.9 (45424165..45457099)
Cluster/Prediction ref. UniGene:   Hs.272813
Protein sequence: HsDuOx01 (DUOX1 / LNOX1 / THOX1)
Sequence Properties
first value : protein
second value (mature protein)
Length (aa):   %s   1551 (1530)
PWM (Da):   %s   176975.66 (174803.5) Transmb domain:   %s   o594-616i1044-1066o1081-1103i1149-1171o1186-1208i1221-1243o (o573-595i1023-1045o1060-1082i1128-1150o1165-1187i1200-1222o)
PI (pH):   %s   7.94 (7.96) Peptide Signal:   %s   cut: 22 range:22-1551
Sequence 2398
Send to BLAST
Send to Peroxiscan
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
MGFCLALAWTLLVGAWTPLGAQNPISWEVQRFDGWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLGEPHLPNPRDLSNTISRGPAGLASLRNRTVLGVFFGYHVLSDLVSVETPGCPAEFLNIRIPPGDPMFDPDQRGDVVLPFQRSRWDPETGRSPSNPRDANQVTGWLDGSAIYGSSHSWSDALRSFSRGQLASGPDPAFPRDSQNPLLMWAAPDPATGQNGPRGLYAFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYNIAVYEWLPSFLQKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPPGVYMRNASCHFQGVINRNSSVSRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAEREDHVLVEDVDFWPGPLKFSRTDHLASCLQRGRDLGLPSYTKARAALGLSPITRWQDINPALSRSNDTVLEATAALYNQDLSWLELLPGGLLESHRDPGPLFSTIVLEQFVRLRDGDRYWFENTRGLFSKKEIEEIRNTTLQDVLVAVINIDPSALQPNVFVWHGDPCPQPRQLSTEGLPACAPSVVRDYFEGSGFGFGVTIGTLCCFPLVSLLSAWIVARLRMRNFKRLQGQDRQSIVSEKLVGGMEALEWQGHKEPCRPVLVYLQPGQIRVVDGRLTVLRTIQLQPPQKVNFVLSSNRGRRTLLLKIPKEYDLVLLFNLEEERQALVENLRGALKESGLSIQEWELREQELMRAAVTREQRRHLLETFFRHLFSQVLDINQADAGTLPLDSSQKVREALTCELSRAEFAESLGLKPQDMFVESMFSLADKDGNGYLSFREFLDILVVFMGSPEEKSRLMFRMYDFDGNGLISKDEFIRMLRSFIEISNNCLSKAQLAEVVESMFRESGFQDKEELTWEDFHFMLRDHNSELRFTQLCVGVEVPEVIKDLCRRASYISQDMICPSPRVSARCSRSDIETELTPQRLQCPMDTDPPQEIRRRFGKKVTSFQPLLFTEAHREKFQRSCLHQTVQQFKRFIENYRRHIGCVAVFYAIAGGLFLERAYYAFAAHHTGITDTTRVGIILSRGTAASISFMFSYILLTMCRNLITFLRETFLNRYVPFDAAVDFHRLIASTAIVLTVLHSVGHVVNVYLFSISPLSVLSCLFPGLFHDDGSELPQKYYWWFFQTVGLTGVVLLLILAIMYVFASHHFRRRSFRGFWLTHHLYILLYVLIIHGSFALIQLPRFHIFFLVPAIIYGGDKLVSLSRKKVEISVVKAELLPSGVTHLRFQRPQGFEYKSGQWVRIACLALGTTEYHPFTLTSAPHEDTLSLHIRAAGPWTTRLREIYSAPTGDRCARYPLYLDGPFGEGHQEWHKFEVSVLVGGGIGVTPFASILKDLVFKSSVSCQVFCKKIYFIWVTRTQRQFEWLADIIREVEENDHQDLVSVHIYITQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSITHFGRPPFEPFFNSLQEVHPQVRKIGVFSCGPPGMTKNVEKACQLINRQDRTHFSHHYENF*

Retrieve as FASTA  
Remarks Complete sequence from genomic (chromo 15, )9 cDNA and 102 ESTs.
DNA ►
Send to BLAST
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
ATGGGCTTCTGCCTGGCTCTAGCATGGACACTTCTGGTTGGGGCATGGACCCCTCTGGGTGAGTACAGATTGGAGGAGAAGCATGGTTAGGAGCAGAGGAACCCAGCATCCTCTGGGCTC
CCCCAAGGACAGGATCCATTTGATATTCATCTGTATCTTTAGTCTCTAGCTGACACAGTGCCCTGCACATGAGAGTTGCTCATTTCTAGCTGTTGAAGAAATAGATGGATAATGGAATGA
AAATTATCCCCAAATACACAGAATTAGGGAGCCTTCAGCTGCTGTCAGCACTTTCTCTTTTATTCTTACAGTTTGGGGGCCCTTTCTCTCTCCTCTCTCTTCTCTTGTTTTCCATAAAGT
GAGGGCCTCTGACTCAAAATAGGAAAAGATTGATTAGACACATAAGACAATAAAGGATCTTGGGGTCAGATTGGACCCAAAGCTGAAGGGGAGTCATCAATATGTTTAAACATTATGATG
AAAAACAAAAGCAATATCTTCCATAAGAGTTTCATGTTGCTGCCTTCAGTAGACAGTTTCTTGCTGGAATCTGAGGCTGCTCTCTGCAGTCCGGATCTCTGTGGAGGGAAGTGGGCCTAC
AGTGCCACAGTTAAAGTTAAAAGATCAAGTCCCTGATCACTGGGGATGGGAGATGCAAAAGCAGAAAGCAGAGAAAACCTGTAGAAGGATCTGTCCTGGCTGGAGGTGACAGGATGGTGA
CACCTTCCCTACAACTTCTCCCTTGCCAGAGCTACTCACATCCACGTTCCTTCCAGCCCTCTTCTTTCCCTAGCTTTGGATTTCCCTTTTTTCCCTCAGCTCTCACCTCTTATCCCCAAG
AGGCGCTTTCCCTGTACTGTCCTGCAAAGGCTCTCTCCTTTATGTGCCACAGGTTCATTTTATTTTAGAGATCACATGTGTGGCCCTGCCCAAAGTCTTGAACCTTAGCTGGGTTCTTTG
CTCAAACATCAGGCCCTGAGTCATTTTCCCCCCTGACTCTCTGCTGAGTGAGTGTGAATGTGTGCGTCTGTTCTCTGAAGTGAGCAGAGAAGAAGCCCCAGGCCTATAGACTCCTAGTTT
GGGGGAAAGAATCAGGCCAGCTATCTGCTCTACTGATCAGAAAGATCCCTGCTCCATCCCTGATTCCATTATCCATTCTGGATCTTCCCTCTGTCCCTCATTCCTCAGTTCTTTCCCCAG
CAGCTGAGTGCTCCCTCCTGGACCCTCATTTTGGAGAATACAACAGGATCAAGAGGAGGAATTGTATGGGGGACAAGATGCCCCAGAAAAAGGGCAAAGTCATCCACATCACCAGTCCAG
TCCCTGGTCCTACCCAAGAAACTGGGGAAAAAAGCAGTAGCAACACCACACCCTTGCCCTGGGCTCTGCTCAGCCAGAGATGACTAGTCCCCTCACCACACCGACCCTGCCCAGGGATGG
GTCACAGAATGACATGTCCTTCTCCGGTATGGAGTGTGGCTGGCTCTTGCTCTGTGTGGTGTCTTAGGGCTGGGGATGGATTCTGTCCTGTTGTGTCCCCTCAGGGAGCTGAAGTTTAAG
GGGAGTAAAGTCCCCTGCATCCTATTCCCCATCACCACTGCTCTCCTCCAGCCCCCTCTCCCTCTCTGAGGCCGTCTGTCAGCACACTCTGCTCCCTGCTCCACTGCTTTTTGGCTCCCT
GCCATGTCTCCCCCACTGAGCAGCTTAAAGATCTGGCTTGAGTTTGGACACTACTTTGCCCTGGTTTTTCCCTCTGCACCCTACCTCTCACATCCACTTCAGGTATCCACTTTCTGCTGC
TCCAAGTGCCAGGCTCACAGCACCCATATCCGGCAGGCCTGCCTGTCCTCTCACGCACTGACTTGCCCAGCTGCCCCTTCCCTCCATTCTCACACAGGAGCTCAGAACCCCATTTCGTGG
GAGGTGCAGCGATTTGATGGGTGGTACAACAACCTCATGGAGCACAGATGGGGCAGCAAAGGTAAGTGAGAGCCAAGTGGGGATAGAACCCCAGGGCCAGGGGGGTACTGAGTGCTGCGG
GGCAAGAGCTGGCAAGTACCAGCAAAGGCCATCCATTTCCAAGGTTTTAGGATCCATGACATGGAGGAAAGCCTGGGAGAGAGGGGGTCAAGAATGCCCCCTGAAGATTCATCCTTATCC
TTACCCCTCCTACCCCAGGCTCCCGGCTGCAGCGCCTGGTCCCAGCCAGCTATGCAGATGGCGTGTACCAGCCCTTGGGAGAACCCCACCTGCCCAACCCCCGAGACCTTAGCAACACCA
TCTCAAGGGGCCCTGCAGGGCTGGCCTCCCTGAGAAACCGCACAGTGTTGGGGGTCTTCTTTGGTGAGAACTTCAACCTCTGGGGAAGGAAGCCGGTGGGGTCGGCTGGACACCTCTGCA
TGTGAAGAGGGGTCAGAGGATGAGAGAGAAGTGATGGAAGGCCTAAGGGATGAGGGTGAGAGGTGGAGGAGGCAGTGGGGTATGGTAGGGGTAGAAGCAGGTGGAGAGAGGATCCATGCT
GAAGTGAACTCTGGTTGGGGAGGCAGAAATCTGCCCCACACAGAAAGATGAGGGGTGGGGTTAGGGAAAAGGGGCATCCCTCCTCGTTGGGTTGTTGGTGGGGGTAAGGGGCTGGTAGAG
GCAGAAACATGAAAATAATCTGGGAGGGCCTCTCCGTGGGACCCTGTTCTTAGGCATTGCCCCATGGCTTCTAGGACAGGCTCAGGGCAGGGTTCTGATTCTGGCAGAGTGGACTGAGGG
GAAGTCAAAGTGGGGGTGCTAGGATGGCTTGACCCCAGTGACAGGATTGGTGGCTGGTCCATCAGGAATGCCTGGCTCCTGCTGCGTTTTGGAGCTGGTGCTGCCGGCCCGTTTGCCTAG
GCACACTCACAGGGCACCTCCCAGTTACCAAGGAGAAAGCCAAACTGTCAACGACAACAGCTTGGATCAGGTGTAGGCACAGAGGGACAGAAGAGACAAACAACTGGGAGGGAGTGCCTA
AGGTCAGGGCTTGGACTTGCCCATAATGGCTGCTGAGTCTTTTGAAGCTTCAGGGGAGGGAAGGAAACTGGATACCTAGGGTAAGAAGGAAAGTGGCCCTCTGCTTGCCCTAGCACCCCC
TCCTGCACTGCCCGCAGGCTATCACGTGCTTTCAGACCTGGTGAGCGTGGAAACTCCCGGCTGCCCCGCCGAGTTCCTCAACATTCGCATCCCGCCCGGAGACCCCATGTTCGACCCCGA
CCAGCGCGGGGACGTGGTGCTGCCCTTCCAGAGAAGCCGCTGGGACCCCGAGACCGGACGGAGTCCCAGCAATCCCCGGGACCCGGTGAGGCGGGGAAGGCGGCGGGAAGGGACCGCACC
CCAGCCAGGTGGGACCTGGGCTTCGGGCCTGGCAGGGCCTGGAGGGGAGAGGCGCCCACTCCCCAGCCGCGGACACCCGCCGGGCCCCGGCCTTCCCTAGCTCGCCGCCGCCCATCGACC
CGGGCTCACCCGCCGCGTGCCCCGCAGGCCAACCAGGTGACGGGCTGGCTGGACGGCAGCGCCATCTATGGTTCCTCGCATTCCTGGAGCGACGCGCTGCGGAGCTTCTCCAGGGGACAG
CTGGCGTCGGGGCCCGACCCCGCTTTTCCCCGAGACTCGCAGAACCCCCTGCTCATGTGGGCGGCGCCCGACCCCGCCACCGGGCAGAACGGGCCCCGGGGGCTGTACGGTGAGGCCACA
GGGGCGGGACGGGGCCGGCTGGGGGTCTGCGAGTGTGGGCTCCCCCGATCACGCTACCGCTCGTCTCCTCCCCTGCGCCCCCACGTCGGATGCAGCCTTCGGGGCAGAGAGAGGGAACCG
GGAACCCTTCCTGCAGGCGCTGGGCCTGCTCTGGTTCCGCTACCACAACCTGTGGGCGCAGAGGCTGGCCCGCCAGCACCCAGACTGGGAGGACGAGGAGCTGTTCCAGCACGCACGCAA
GAGGGTCATCGCCACCTACCAGGTCAGCCGTCCGCGCCCCGCGACGTCCTCCCTTCCGCGTGCAAGCCCACGGGAGACTCCGCTGCCCCATGGAGCTCCCCATCTGTGGACAACCGCCAC
CCAGAAACCCCTCCCCAGACAGCCGAGGTCCAGGGAAGCCCCTGTAAATGATAGGGAGGCACGCGCTGTTTATAGGAGAAATCTGGCTGGTGATGATTATTTATCACCTCCCCACCCCCC
ACTCCCTCAAATCCCCTGGTTCCTTGTGGGGACAGGCCTCACACTGCTCCTGTTTGAGTTGCTTCTCCCATGACTGACCCTGGCTGGTCCTCATCTCCACACGGAAGCCGTCCTTGGGCT
CAGACCCTTCCAGGTCCCTCCCCATCCAACTCGTGCCTCCCCTCGCCCCTCTCTGCCCCTCAGAACATCGCTGTGTATGAGTGGCTGCCCAGCTTCCTGCAGAAAACACTCCCGGAGTAT
ACAGGTGAGGGAGCGGGGAAGGAGGATGGGAGGGCTTGCGTGTGTCTTGCGGGGTGGGGTGGGGACTACGTTGGGGATTTTAGGGCTAAATTCTTCTGTCCTCTCTTCTCCTATTTCCCC
AGGATACCGGCCATTTCTGGACCCCAGCATCTCCTCAGAGTTCGTGGCGGCCTCTGAGCAGTTCCTGTCCACCATGGTGCCCCCTGGCGTCTACATGAGGTGAGGGAGGGGCTCAAAGGT
GTGTGTGCTGGGAGGGATGGGGCTGTCAACTGAGGAAAATCTGCCCTCAGGAGCCCTCTGTACAGGATTATCAGTCTGAAGTGTCCCCAAGGGAAAGACCGATAGAGAGGGGAAGAAAAC
AATTGTTTTAAAAGATACATCACTGTGGTTTTTAAGTATTTTTACTTCCATTCTCCTGCTGCTGGTGTAGATATTACCCTCCCCCCCACCATTAAATATAGAGTAATAAAGGTTCAGAGG
GTGTCACAAAGTCCACTGGTCTAAACCTCATGTCTTGACACTACACTGGGGACATTTTTAGCTATAATCACAGAGCCCAGGGCCTGCAACCTTTTGGGGGCAGAGGGTTCTAAAATGTGT
GCAATCTGAAGGAAAATATTGGCTTCAAAATAATGAAAAGGGAACTTTAAAAAGACATAGGCCGGGAGCAGTGGCTCACGCCTGTAACCCCAGCACTTTGGGAGGCAGAGGTGGGTGGTT
CACCTGAGGTCGGGAGTTAGAGACCAGCCTGACCAACATGCAGAAACCTCGTCTCTACTAAAAAAAAAAAAAAAAAAAAAAAAATTAGCCAGGCATGGTGGTGCATGCCTGTAATCCCAG
CTACTCGGGAGGCTGAGGCAGAAGAATCGCTTGAACCCAGAAGGCGGAGGTTGCGGTGAGCCAAGATCGTGTCATTGCACTCCGGCCTGGACAACAAGAGTGAAACTCCATCTCAAAAAA
AAAAAAAAAAAAAAAAAAGACACATATTTAAATAATGTATATGTATGTATATGTATATGAAACAAAGCATGTCCATTTATATTTTTACAATTGCTTTATAATTTAAAACAATTCATAGAT
TAGATTTACTCTGGAATAATCTCTGGGGTATGCCTGATGATGTCTGAGAAATAGACAATTGAGTTATTCATAGACAAGTAGTTTCAGAAGAACAATTTTTGAATCCTTTAAATAGGTATA
TATGTACACATATATTGTACATATAACTGTGTATATATATATTTTATATGTGTGTGTATATACATATATTGAGAGAGAGTCAGAGAGAGAGTGTGTGTGTTAATGAGCTATGAGTACATT
TTAGATATTTGGTCTGATGTTGTAGATGGGACCTTCCAAAAGTCAGACCCTCCAGGATGTGCTAAGGTCCGAACCACACACCACCTCGGAAAGACGATGGCCTGGGGTCCCTGGATACCG
CCTCAGAGACCAGAACTGATGCCTGACATTATAACCCCATTATCTCAATCACCATCTCCCTGCTCCTTGCATTTCAGAAATGCCAGCTGCCACTTCCAGGGGGTCATCAATCGGAACTCA
AGTGTCTCCAGAGCTCTCCGGGTCTGCAACAGCTACTGGAGCCGTGAGGTCCGAGCTGGGGGCCACATATGTGGTGGATGTGTGTGTGTGCATGCTTATGTGTGTGTGTGTATGTGTGTG
TGTGTGTGTGTGTGTGTGTGAGTGCATGGTGAAAGTGGTCAGTAAGGCTGACGCAGGTAGCTGGGATAGGCTGGGGTGAAGGAGGCAGCCTGGAGGACCTCAGGCATCTCCCCTACAAAG
TCTGAGGTGACCAGGTAGCTGAACATGGCCAAAAGCCAACCCACCACCCCAACCTCAGGGCTGTGGGAAAGCCAGTGGGACCTGTGCAGGTATGGTTCCGCCTTCGTTGCTCCCTCTCAC
GTTTTCCCTCTCCTTCGACAGCTTTGGGCGTCCTGTAGGCCTTGGAGTACCCCAACTAGTCTCACTTGCCCCAAGGAAACATCCCATTAGACACACATCCCGGGCAGTGTGTGAATGCGT
ATGTGTGAGGGGGGTGGGGAGGAAGCAGGGGTTCCTAGAGATTATTGGGGATTGTCCATCCATCCAAATCAGGCCAGCATGGGTGAAGAACATTGATTGTGAATTTAAAGCAAAATGAGA
TACTTTGTGTAAAGTGTTTACTAAGGGGAAGGGAGTGGGGAGGAAGAAAAAAGAAGCCATAGAATCAGAGCCCTGGAGCTGAGTTGAAAGAGGACTCAGTGTCCCCCTCATCAGAGTCCC
TTTTTATTAAGGGAAGGAAACTGAGTTCAGAGAGGGCCTGTGACTTGCCCAAGGTCATACAGCTGGTTAGTAACAGAGGACTAAGACCTAGATCTTCTGGTTACTTTGCCAACCACACTG
TCAAGTATCCCAAGGTCAAAGTAAAATTTTAAGATCCCTTGTGCTTGTATAGACCTCTGTCAGGCAGCACTGACAGAGGGGACACCCCTCACCCTGAGTGGGGAATCAACCTGCAGAAGA
GGAATGTCCCACCGGTTTGGGAGCAAACAGCAGGACTGGGTGGGCTCAGGGATAAGGATGATGGTGTGGAGGGAGCCGGCTGTCTAACCTCTGACCCCATTAACCACACCCCTTTCCTCC
CCACCCCCAACCTATAAAGCACCCAAGCCTACAAAGTGCTGAAGATGTGGATGCACTGCTGCTGGGCATGGCCTCCCAGATCGCAGAGCGAGAGGACCATGTGTTGGTTGAAGATGTGCG
GGGTGAGTCTGAGGCTGTCCCTGCAGGTTGTGAACTCCTGGCCTCTGGGAAGAGGCTCAGCTGGACTTCCAGAACCAGGTATGAGGGGGTGCCTGGGGCTGGGAGCCTGCACTGCACTCA
CTGATGAAAGAGCTTCTGACATGCTGACCATGGCTCCTTCTGGCTCAAGTCTCCTGGGGCTGGTTGGAGCTTGGGGCCTGGACTGGACACTGCTGTGGTGGCCCTGAGCTCCCTCAGACT
GTCTGGTATCTTGTCTCCAGATTTCTGGCCTGGGCCACTGAAGTTTTCCCGCACAGACCACCTGGCCAGCTGCCTGCAGCGGGGCCGGGATCTGGGCCTGCCCTCTTACACCAAGGCCAG
GGCAGCACTGGGCTTGTCTCCCATTACCCGCTGGCAGGACATCAACCCTGCACTCTCCCGGAGCAATGACACTGTGAGGAGGGGTCAGGACCCAGAGGGTAGGGCGGGAGGGACAAGGCA
CGTGGGCCTGAGACATGGAAGATAGGCAGTGAAACTTGAGCACAAGAGACAAGCACCTAATGGGAGGGGCAGGGCTTACCCAGATCACTTTTCCCAATATTACATATCAGGATGAAGATT
ACCAGACCAGCAAGATTTGGCTTTGCACTCGGATTGTTCAGATCCAGCAAGCGTGTATTAAGCATCTATTGTTTGCTAGGCACTTAATAGTCACTATCTTATTTACTGTTCTCTCCACCC
TCCTGAGTGGGTATAGAAGGTCCTTGACTTAGGAACAATCTGTGCTTTCTTGCACCGATGTTTAAGCCACCTTTCAGGAGTCAGCTGTTACACCCTGAGCTACCACCTGGACTGGTGGCC
CAGGCCAAGGTAGAGCCTGAGGCGGAGGCCCAGCATGCCTTACCCATTCCTGGTGTTCTCAAACCAGTAGCGGTCACCATCCCACAGCCGCACAAATTGGTCAAGGATGATGGTGCTGAA
CAGGGGTCCTGTTCAGCTGCTAGCCAAGAGACCAGATTGGGATACCTTACCATCTTGACACAGCAGTGTTTCTACAGTTGTGTGCCTATTCTATTGCATTTTGCCCTTACTATTTTATAA
AATTATTGGAAAGTGGGGATTTGAAAGGCCAATAAAGAAGTGATATGAGCATGGGGGCTCGTAAACTTTATAAAATCAATATATAGATAGGAACCACCAGGCACACCAAAAGTAGCAAAT
CTTTAGCTTCAAATGGGCCTCAGTGGGATTAAGCTGGTCAAGTGCTATTTACACTGTGGAGAAAAGAAAACTAAAATAAAGGTCAGGTAGAAAATGCTGGTGATATGTTTTTGAAAACTG
TCTCCAAAAGGCAATATATAATCAGGCATTTGATTAAAAAAAATTTTAGTTCTAAAGAATAGAAACCTTTTATAACACATCATTCTGCCATTCAACTTTTGCACATTCTGATTTTGTCCC
TTCAACTTTCATACCTTTTCAAGAACAAGTTATGAATGCGGATTGGCTGGCTGTTTTATTACTTTATAAAATAGGCAGCTGAATGTGTGAGAGGGTTCCCATAAATGGAGTTCACTTATG
TAAAACACTCAGAGAAGTGCCTGGGGCATAATAAGCACTGTATAGGAGTGAGTTACTGTTACTGTCATTTATTATTATCATCCCTGGGGCTAATCCCTGGGAGCCACCTCTTTGCCTTAG
GGTGGGTGCCGTGTCCTTTCTCTTACTTCTGCCCCTTCTTGGTTCCAGGTACTGGAGGCCACAGCTGCCCTGTACAACCAGGACTTATCCTGGCTAGAGCTGCTCCCTGGGGGACTCCTG
GAGAGCCACCGGGACCCTGGACCTCTGTTCAGCACCATCGTCCTTGAACAATTTGTGCGGCTACGGGATGGTGACCGCTACTGGTTTGAGAACACCAGGAATGGGTAAGGCGTGCTGGGC
CTCCGCCTCAGGCTCTACCTCGGCCTGGGCCCCAGACCCTCTTTCTGGCCTTAGACAGCCCCCATGAGCCCTTGATTCCAAGCCAGCCCACCACCCACTTCCCAACACCTCTGGGTCTCT
TTTCTCACCTGGGTCCTTGGGCCTGGGGTTGCTGGAGGCCTGCATCCCCTTCCCATCCCAGTGACTTCTACTTACTCCAACTTAGGCTGTTCTCCAAGAAGGAGATTGAAGAAATCCGAA
ATACCACCCTGCAGGACGTGCTGGTCGCTGTTATCAACATTGACCCCAGTGCTCTGCAGCCCAATGTCTTTGTCTGGCATAAAGGTGAGTGGCCAAGGGGTGGCTGGAGGAGTGGTGGGT
CTGGAGCCTCGTCCCTCTTCAGCTCTGGGCTTGGCTCAATGTGGCTGAACGTCAATCTCTGTGCTCCAAGAGGGGAGTGAGCTGTGGTTCTGCCCTTGGGAACTCCAGGTGCCAGGGCCA
CCACTTGCAGCTGTGTAGGGTCCCCTCTGCAGAACTCCAGGAAGTGCTGAGTGAGGGCAGAACTGAGACTCAGAGAGAGCTGGTGAGGAGGTTCACATTCGGCTGAGATGGAGCTCGGGC
TAGGTATAATATTAGGAGGGCTCAGTGCAGTGAGGATATCCCAACCCTACAGCAGTGAGGGAAGCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTACACTTCTGTGTGTGAGGGAGAG
ATGGAGGTTGGGATTCATTTTTTACCCCACTTGTTACCCAAGGCAGCCCCTTCCCCTCAGCTACCCAGAGTGCCCCCACCCCCTTTCTGCCACCCTAACCTCCTCCGTGATCCTGTGCCA
GCACCTGTGGCCCAGCACCCAGGACGCTGGCTTCCTCTGCCTTCCCAGGAGACCCCTGTCCGCAGCCGAGACAGCTCAGCACTGAAGGCCTGCCAGCGTGTGCTCCCTCTGTTGTTCGTG
ACTATTTTGAGGGCAGTGGATTTGGCTTCGGGGTCACCATCGGGACCCTCTGTTGCTTCCCTTTGGGTAAAATCATGGACAGAGTGGGGTGGGGTGAGAGATGCAAGCTAGGGGATGCAG
TTTGGGTGGTTCCACTAATGACAACAAACCACGCAAACCACACAGAGCATGGTCCCTTTGGGTAGGAGAATGAAACATTAGAGGAGGAAGGGACAAGAGAAGTGTTTGACCTGCAGAGAA
GTCAGCTCCAGGGAGAATTGCCTCCCTGTTTTCCTGGGACTGCCCCCAGGGCCCAGCATTGGTCAGGAGCCAGGGGGAATCTATAATCCACAGCTTTTTGCAGGCCTGAGCCTAGAGGAC
TGTCAGAGGCAAATCCCTGTTTAAGAACAAGGGCTAAGACGGGGCGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGAGAGGCCGAGGCAGGCGGATCACCTGAGGTCAGGAGTTTGAG
ACCAGCCTGATCAACATGGAGAAACCATGTCTCTCCTAAAAATACAAAATTAGCCGGGCATGGTGGCGCATGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCAATTGAA
TCTGGGAGGCAGAGGTTGCAGTGAGCTTAGATCGCGCCATTGCACTCCAGCCTGGGCAACAAGAGCGAAACTCTGTCAAAAAAAGAAAGAAAGAGAGAGAGAGAGAATGGAAGGAAGGAA
AGAAGGAAGGAAGGAAGGAAGGGAGGGAGGAAGGGAGGGAGGAAGAGCAGGCTGGGGCAGACATAGTCGCTGGAGTGAGGGCTTGGGGCTTAGTCTTTGGCAAGGCTGTGTGTGGGTCAG
CTAGCAGCCTGGTGGGGTGAGTCTAGTCTCTGACACAAGGACTCTGGACTTAGTCTCTGGCCAGGAAGGGACGTGAGTGGTGGAATCTGAGGAGGAAGGGTGGGTATCTTAGATGCTACC
CAAAGCTCCCCATGGGATGCAGAGCAGCTTCCCCCAGGGACCTTCCCAATCTGAAACAATTGAGCAAGCTGACCTAGGAGGTGGGGACAATAGGTGGTATTGCCAGGTAAGGAGCTGAGA
AAGGAGCTGCTTCCATCCCCTAGACCCCCACGTCTCCCTGAACCTCTGCCTCTGCCCTCCCAGTGAGCCTGCTCAGTGCCTGGATTGTTGCCCGGCTCCGGATGAGAAATTTCAAGAGGC
TCCAGGGCCAGGACCGCCAGAGCATCGTGTCTGAGAAGCTCGTGGGAGGCATGGAAGGTAGGTCTAGGGCTGGCCAGGGTGGTGGTAGGGAGGACATGGCTCAGCGCTACAGCTACCCAC
CTCCACCCCAGCAGCCTAAGGAAAAGGCCTCCCTTTTCTAGGACTGTAGGCAAGGCCACAGTGGCATTAAGCAGAAGTTGGACATGGAGTCCTGCAGCCTCCAGAGTTTCTCATGTGCAG
CAGTCATTGGACCTTGCCTTACAGGGAGTAAGTGTAAGACCCTGTAGTGATCTTACAGGGTCACTATGACTTACGAATCCCTGGGAACTGCTGATTTGTAGCATCTCACGCTGGAACTCC
AGGCAACAGAGAAGTGGTTAATGAAGGTCCAGAGTCAGACTGGGATTGGAATCTTGGTTCCACCACCACTATGGGCTATTGGGCCTTAGGCAGATTTTTGAATCTCTCTAAACCATTTTT
TTCTTATCCATAAAATAGGAATAATAATAGCACCTACCTCACAGGTTTATAATTAAATGAAATAATTCATGCAAAGCACTTGGTATAGTATTGAGCACATAGAAAACATTCAGGAAATGA
TAGTTACTATTCTTTTCATGGGGCTAGAGGCACAGCCAGGCTTTCAGGGAGGGAATGACTCTCAGTACCCCAGAAGGGGACAATGAACTGTGGAGGCCTTGATCTAATTTCAGCCCTGAG
CTGGCCCTCTTCCTCCCAATGTACCTCTGATGGGTCCCAGCTGACGAAGCCCTGTCTCTCTCCCCCTAGCTTTGGAATGGCAAGGCCACAAGGAGCCCTGCCGGCCCGTGCTTGTGTACC
TGCAGCCCGGGCAGATCCGTGTGGTAGATGGCAGGCTCACCGTGCTCCGCACCATCCAGCTGCAGCCTCCACAGAAGGTCAACTTCGTCCTGTCCAGCAACCGTGGACGCCGCACTCTGC
TGCTCAAGATCCCCAAGGAGTATGACCTGGTATGGCTCAGCTGGCATCTGGCTCCTTGTCCACAGCCAAGGCCAGGGAGGCAGCCAGGTGGAGGGGAAGAAGCATGGGGTCAGGAGGCAG
GAAATGATAGTTACTGTGCAGGAGTCTGGCTTCTTGTTCCCAGGTGGAGTACCTGATAGAGAGATAAACTTGGACACGTTTATCCTGCTCCGGGTCTGCTGGATGACATAATCTCCATGG
TTTCCTCCTAACTCTTGCAACCACAGTCTGCCTCCTCCTTTTCTAAGGACAACCTGTCAGGTCCCAGCTGGGTGTCCTTGGAAGAAGCAAAGCCCTCTTCCCTGTCCTCTTATCTCAGGA
TGTAGTGAATTTTTAGAGATTTTGGAGGAGAGCTAAATCAGAGGCCTGGCCCATGATCCCCTCCATCCTCTGGCCTTCCTGCCCTCCTCTGCCTTCTCCAGTATGGAATAGAGGGAAGAA
TGTCTTTGTACATGTGCCTTTAAATCCAAACTCTGCACCTATGAGCAAGTCACTTAACCCTACTGAGCCCCTTTCCTCTTCTGTAAAAGGAGAAATAATATCCCTTTTTCAAGGCCACCC
CAGTGGCCCCTCTGACATAATCCACATAAACTGCCTAACCTCAAGAGGCCTTGGCAAATGGTTGCTTTTGCTCGGGCTGCCCCCTTAGGTGCTGCTGTTTAACTTGGAGGAAGAGCGGCA
GGCGCTGGTGGAAAATCTCCGGGGAGCTCTGAAGGAGAGCGGGTTGAGCATCCAGGAGTGGGAGCTGCGGGAGCAGGAGCTGATGAGAGCAGCTGTGACACGGGAGCAGCGGAGGCACCT
CCTGGAGACCTTTTTCAGGCACCTTTTCTCCCAGGTGTGTACATGGGACCAGATCAATCCTTATGCTGTGGTGGTGTCCTTACCTGCATGAGGCCATGGGGTGACTCGAGGGGAAGTCAA
AGCCCAGAGTTCTCAGCTAATAATCAAGTCTATTGCAATTTTGGATGAATCACCAGACTTTATCATAAGGAGTTGCCCCTGCCCCCATCTGAACCCCACCTCCAACTACGAGGCTCCAGT
GGGGGGATGCCCAGGAATGGGCTTCTCTGCATGTGTTGCTTATCGCTCTCCTCAGGGCTGCCCAGACTTTCCATCCTCACTCATCTCAGCCTGCCTCAAAGGCTGCAGAGACCCAGAGCA
GCGTGGGCACCATAAGGGATATTGTTCACCCCTTCTTGGGGGAGTGCAGCTGCCAGAGCCCTCCATGGGGCATTGATGTCCACCTTGCAGACTTCTGAGAGAGACTGGGAGGATATAGGG
AAACAAGACAAAAATGCAGAGACTTGAGTCCACAGCTGGCACAAAAATAGAGGCAGCCTGGGAGCAGGGTAGTGGAGTGGAGAAACATGGTAGATAAAGATAAATATGGTCAGGTGCGGT
GGCTCACACCTGTAATCCTAGCACTTTGGGAGGCGGGGCAGGTGGATCACTTGAGGTCAGGGGTTTGAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAAT
TAGCCGGGTGTGGTGGCGGGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGGCAGAGGTTGCAGTGAGCCGAGATTGCACCACTGCACTCCAG
CCTGGGCAACAGAGTAAGACTCCATCTCAGTTAAAAAAAAAAAAAGATAAATACAGCATGGTTCTCCCACTGAAGAAGCTTATCCTTCCACTGGGGAGATGGAACATGCACAGAAAGGAA
GATAACTGGCAAAGAATGAAGGCTACAAAAGTGATTCAGGAAATCAGCAATCCGGGAGCTCAGAGAAGACAGTGAGTCTTCAGCCTGCTGTGAGATCATGATGGAGGTGATATTTGGCAA
GGACTTAAAGTTGGACAAGTTTTGGCTCAGAGGAAAGGAACAGGAGGGACTAAAAAGAGGGCTCCATGGAAGAGCAAAGAAATTAATGTTTGAGGAGAAAAAGCAGGATCATGTGGTTGG
GGAGAGGATTCATGAGAGAAGCATCCATTGAACAGACATTTACTCTGTGCCAGGAACATGATTTAAAGTCATTTGAGGACAAACAAGTTGAACTTGAATATGTACAAGAACAGAGGGACC
CTCAGCTGGGTGACTCCTTCCCAGAGCCCAGGCAGGACTGGGCATCTCCACTCATTCAGGATCCTTCGGGGCTATGGGAACTCCCTGTGCTGAGACACGAAGGGTGCTGATATATCCTGG
GGGTGGCTGTCAGTGTCTCATATGATTTCAGCTTTCAGAACATTTTCAACACAACCACTTTTGTTGATCTCGCAATAAACCTGTGAGATAAGTAGGGCAGATGAGGAAATGAATTCCAGG
CAACCGAAGAGACTTGCATGAGGTCATTCAGCAAGCAGGTGACAGAGTTGGGACATGAACCCAGGTCTCTTGCCTCCAGCCCTAGGCTCTTCCCACTACAGCACCTTGTTTGAAGCTGTA
AGGTTTACCCCATGAAACCATCACCAGACTTGGAGTAGGCACCTCACTTGACAGGCAGGAAAGACAGGTACTGTGGCCTGTGGCCTGCCTGCTTCCTCACTGTCTGTTCTCTCATACTGG
GGAAGCCTCTGGGTGGGCTGGGGATGGCCACAATGAGAATTCCCCTTTCTCAAGCCCAGCTTTTCCTCAATCCAGCTGAAGCCTTGTCTTAGTTAAAACTTTTTTTACACATAAATAAGA
GAAACCCCAATAAGCTAGCATTGACAAAGGGTCACTTGACTCTGAGAATACAGAGATGTCTCAGGAATTCCAAAGGGAGGACATCAACCTGGCCTGAAAGGACCTAGAAAAGGAAAGCTG
TCAGCCAATGAGGCCACTCCTCCCCTAGGCTGCCTTTGCCTTACTTGATCTCTAAGTGGCTGAGCACTTGGAGGAAGAGAGTGGTCCACACTTTCTGAGCTTTCTTGTGCTCAAGTCAAG
ACAGACCTCACACTTCTTAATTCCAAGTGAGTTCCCTGTCCAGTCAGCTAAGGCAGAGGGTCAGGGTTCTGTAGAACAAACATGGCCTCAGGCACCACCATAAGGCCTCCTAGCAGAGGG
GGTCCTGGGCAGACACCTCAAAAGGTGGCTCCTACAGGGCTCAGCTGAACTTCAAGTCAAGGAAGCCTTGTCTCCTCTCCCTCCCTCTGCTTCTGCCCAAGTGCAGGTGCTGGACATCAA
CCAGGCCGACGCAGGGACCCTGCCCCTGGACTCCTCCCAGAAGGTGCGGGAGGCCCTGACCTGTGAGCTGAGCAGGGCCGAGTTTGCCGAGTCCCTGGGCCTCAAGCCCCAGGACATGTT
TGTGGAGTCCATGTTCTCTCTGGCTGACAAGGATGGCAATGGCTACCTGTCCTTCCGAGAGTTCCTGGACATCCTGGTGGTCTTCATGAAAGGTGAGGGAGGAGGGAATGATAGGAGAGG
CTGGACAGGGGCTGATCTGTTGGAGATGGGGAAGCCCTGGGACCAGGTCTCCAGCCATGGCAGATGCCCAGAAGTGCCCAGGCCGAGGTCAGGAAGCAGAGCGACCCTTGCTGTGTCCAG
AAGTGGGTCATCACACTGGTGTGAGGCCCCTTTTGGCCAGCCTGGGGGTTCAGGCAGGCAGGCGGGGGCTCTCCTTATGGAGTCCTCCCTCTCCCAGGCTCTCCTGAGGAAAAGTCTCGC
CTTATGTTCCGCATGTACGACTTTGATGGGAATGGCCTCATTTCCAAGGATGAGTTCATCAGGATGCTGAGGTTTGTTCTCTGGGACAGCCAGGAGAATGGGCCAGGGCAGGGATGCCAG
GGCAAATAGATGGGACCTGAAGGAGAGAGCAGAAGGGCCAAGGAAGGAAGCCTCCTCCTTACCCATGTAACCAGAGGCTGTTCAAACTAGCAGGGGGCTTGGGATGTGGCCAGTCGGGGC
CCCTCCACATGGGCACAGAGAACTTGGTGCGATGGAGTCAGTGTGTCCTGTGTCTGGGTCGCAGGCCCCAGTCAGGGCCGGATGGTTCCTCTCCCCCAACCCCAGATCCTTCATCGAGAT
CTCCAACAACTGCCTGTCCAAGGCCCAGCTGGCTGAGGTGGTGGAGTCCATGTTCCGGGAGTCGGGATTCCAGGACAAGGAGGAACTGACATGGGAAGATTTTCACTTCATGCTGCGGGA
CCACAATAGCGAGCTCCGCTTCACGCAGCTCTGTGTCAAAGGTGGGGCAGCCTGGTAGGCAGCACTGACTCATTGGTTAGGCATAGTAGGCACAATGCCCACATACTTTTAGGAGTCCAC
AGAAATGTTTTAATTTCCATTAAAATCAGAAGAAAAAAATGAATGTAGTAATATGTAATAATGTATCCAATCTGGATTGTAGTTTTCTTTATATCAACATAATTATACAATATAATTTTA
AAATATTATTTTTTATTTTTATGGAGGAAAGGACCCAAAAAGGTGAAAGTGCCTAGGGCCCAGGAAAGTCATAATGCAGCTCTGCTGGTGGGGTGGGTAGGGTCAGGATAGGGTAGGAAA
TGGTGATTGGAACTCTGCTTCCCCTGGCTCCCTGCCAAAGCCCCCTGTGCGTGGTGCCCAGGGCAGGGGGAGACTGTCTCCCTGTTACAGCCCTACCCAGGCCATACTTCCTTCAGCTGG
GATGTCTGGTTGTGGGGGTGGGGTGGTATCTCTTGGGGTTTTTTTTTGCCACTATATCTCCTGGCTGAGTGCTCAGTAAATGTTTGCTGAATACATGAAGACCCAGTTCTGTTGTCCTTC
CCCCTACTTCCTGCCCCACCAGTGTCTGATTCAAGTGGGTGGGGGCTAGAGTTAGAGTGAGGAATGGGCAAGCAGCAGGCAGGAGGGTCTGTCTGTGGCCTGCTCTGAGCTGTTATGGTA
TCTTTGCATCTTAGGACTCTCACTGGGGCATGTTGAGACCAAACCCAGCCCCTCCCAGAATTATGAGAAGGGGTAGGCTGAGCAGCCTCCACAGGGAAGAGGGGCAAGTTAGATAAGACA
CAGATGAGCCTCTGGTCAGGGCTTCCCCCTGGGGGTAAGGAGAGCTGGAAGAGAAGGAACCCAGCACTCCTGATTCTGCAGCTTTTTACCTTTCCCAGGCAGCCAGGGCAGCAGGCACCT
GAGCCTAAGGGCAGGGGCAACGAAGGTGCATGGAAGGGAGCCCACACCACAGAGTCCCAGGGACATCCAACACCTGGGGTGGAGGGTAAAACCAGGCTTGGGGATTGAGGAAGATTAGCA
CTGAGTATTGTTTTCTTTTAATTGTTATTGACTCCAGATTTTTTTTATAAAGATTTTAAAACTAAAGAAAAGGAACAAAAGGCCAGGTGCAATAGCTCATGCCTGTAATCCCAGCACTTT
GGGAGGCCAAAGTGGGAGGATCACTTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATAGAGAAACCCCATCTCTATTTAAAAAAGTACAAAAATTACCCAGGTGTGGTGGCACATGC
CTGTAGTCCCAAGTACTCCAGAGGCTGAGGCACAAGAATCGCTTGAACCAGGAGGCGGAGGCTGTAGTGAGCCAAGATTGTGCCACTGCACTCCAACCTGGGCGACAGAGACTCTGTCTC
AAAAAAAGAGATGTTCCTTCACTTTTCACCTAGATATGCTATTTGTTACCATTTTACCACATTTGCTGTTTGTGGAACATTTGAGAGTACAGGCATTAATACTTTGTTTTAAACATTCTG
ATTTAATTTTAATATAGTTCAGCTTATCTTCTTTTGACCTCAACTATAGACCAGGGTCATCTTCAGGCTTGGTTCAGCACTTGGAAGAAACCCAGAGATTCCCAGGACTCCTGTAAGAAT
TTGGCTTTGCAGCTTAGTCCTGCCCTGCCTTCAGTGCTCAGCCTAGACAGGAACAATGGGGTGGCTCCTGGGAGAGCTTTTCTCCTGCATATTTTATTATGAACATTTTCAAACACAGAA
AAGTAAAAAGAACTGTAGCGTGATCTCCCATATACCTACCACCTAGATTCTACATTTAGCTCTTGGAGGTTTTAAGCTAGAGGATCTTAAGCCAAATTTTTATGGCAGAGCAGGCTCAGA
AGGCAGGTTATATACAGTTCCCGAAATCTACCCCATAGTCCCAGAAGTGGGACTGATGATGGACACACTTTAGGGAAGCCTGCCTGGCCAACTTTCTTTCAGGCCTTTTCCCTGCCCACC
TATGGCTGGGTCCAGCTCCCATTGGGGACAAGGGCTGAGGTTGGAGCACCCGAAAGCAGGGCCTCCATTGGTCTGGGACTGTCTACTGTGCCTGAGCATGGGATGGTAGGAGTGCTGTGC
GTTTGAGCCAGGTCTTCCTGGGCTCTGGACCCTGAGCTGCTCCCTAGCCTGGCTCTGCTTTGCAGGGGTGGAGGTGCCTGAAGTCATCAAGGACCTCTGCCGGCGAGCCTCCTACATCAG
CCAGGATATGATCTGGTGAGCACCCATCTGGGAATGTCGGGGGGAGGAGTTGGGGAGTTGCCATTTCTCTCCCCTGAATGGCTGGGATCAGGGCCACCGCTAGCCCATGCAGCACCTTCA
AACAAATTAGAAAAGGACACCCCTTTCTCTAGGCAGACACAGCCCTGTGCCAGGGCAAGCAGAAAGCCTGCTGGATTTCCGCTCTCACTTACGGCCTGGCCCAGATGCCCTTGTGAAGGG
TAAAGGCATATGCAGCAGCCTTAGCGAGGACCCCCAAGATCAGACTCTGTCTATAGGTGACTGTGGGAATCCTGCTGTCCCCTTGCTGACAGCTCTGATCCTTCCTCAGCAGAATGGGTT
TGGAGGCAGACCAGGATAGCAGAGGAACGAGTGGTTGAGATGGCCAGCATCCTATCTCTTACCATTCTTGTCTTAGTCCCTCTCCCAGAGTGAGTGCCCGCTGTTCCCGCAGCGACATTG
AGACTGAGTTGACACCTCAGAGACTGCAGTGCCCCATGGACACAGACCCTCCCCAGGAGATTCGGCGGAGGTTTGGCAAGAAGTATGTCTGCTCTTCCCCTTAAGCCCAGGCAGTTCATC
CATTCCTTCAGCTTATAAACATCTTTTCCTTGGTGCCAGGCACTGTGCTAAACATTGTGGGTACAGGCAGGGTGAATAGTCCTTGCCCAAGAACATCACAATCTAAGAAGAGAATCTGGT
ACACTGATAATTTCAATGTCCCACTGATGACTGTTCTAATAGTGGTAAGAGCGAAGGGCTTTGGAACTCAAGGAAGCACTCACCTCTGCCAGGGAGGTCAGAGATGCCTTCATGGAAGAG
GTGTCCTTTGAGTCTCTAGTAAAGGCTGAATATGGGCGCCGGGTGGGAGTTGGGAGCTACAGACTGGAAGGAGAGGGACTGAGTGTGAATGAACACAGGTAGATGGAGTACATCCCCTGG
GAAGAAATGACCACTCCAAGCCATCCCTCCACTGCCAGCTTGCTTATGCAGTGCAATATAGCCTGATGCGGTGAGGTCTGAACCCTTCTTCCACAAGGGTAACTAGGTTTCTTTCTCGGA
AGCAGTGGGCTTCCCTCACTTCTGGGCGGCTCACCTCCGTGAAGTGGGGCCCCACTAGCGTTGGGTCCCATGGTGGGTGCCAAAGGCTAAGGCTTCCTGTCTCCCAGGGTAACGTCATTC
CAGCCCTTGCTGTTCACTGAGGCGCACCGAGAGAAGTTCCAACGCAGCTGTCTCCACCAGACGGTGCAACAGTTCAAGCGCTTCATTGAGAACTACCGGCGCCACATCGGCTGCGTGGCC
GTGTTCTACGCCATCGCTGGGGGGCTTTTCCTGGAGAGGGCCTACTGTGAGTGACTTTACTTACCACGAGCCCTGTCCCTAGGCTTGCAATGAGTGATCGCCCTGGGGGTGGGGCCTGCG
ATAAGTGCCAGCCCTGGGTAGGGTAAGTGGAGCCTGTCTGAGTGAAGACTGTGCGGGGGAGGCCTGTTGTGAGTGGCAGCCGGCCAGGGCCTACCGCCCCTAACCAGCTCTCTGTCCTCT
GCACTGACCCTCGCTTGCCTGCCTGGGCCCCCTCCACAGACTACGCCTTTGCCGCACATCACACGGGCATCACAGACACCACCCGCGTGGGAATCATCCTGTCGCGGGGCACAGCAGCCA
GCATCTCTTTCATGTTCTCCTACATCTTGCTCACCATGTGCCGCAACCTCATCACCTTCCTGCGAGAAACCTTCCTCAACCGCTACGTGCCCTTCGACGCCGCCGTGGACTTCCATCGCC
TCATTGCCTCCACCGCCATCGTCCTCACAGGCAGGGCCTGGGTGTCCCTGGGAGGCTCTCCAGGGCCTCCCGCCCCCGCTGACTTCCCCTCGTATGAGAGCCCCCCTCTCTGCTGGCACT
TACCTTTAATGTCCTTCTCCATCAGGATGGAGTTGGCCTGGGCCAGGGTGTGAAGTAAGCCCGGGAGCCTGTCGCTGGTCACTTCCAAGTGCCTCTTCCCGCACTTTCCAGGGCGCCTCA
CCAGCCTCAGCTGACAAGTTACTAACACCCCAGAATGAGTGTGCATAATGTGTCAATTCTCCCAATTTTTATGTTTTAAAGCATGACTCTGAGAGAAAGCAAAGGAGTGAACTTCTAATG
CTGTAATTTCAGACTCACATGGTTGCGCACATGGATGGTGTGTCTGTGGGGTGTTGGGTAGGGCCAGGTGATTGTTTAGAGGTCAGAAGTCCAGGCCGGCGCGGCGGCTTATGCCCCTAA
TCCCAGCACTTTGGGAAGCTGAGGCGGGCGGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATCAGCTGGGTGTGGT
GGCACATGCCGGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATTGCTTGAACCTGGGAGGCAGAGGTTGCAGTGAGCCGAGATCGCACCACTGCCCTCCAGCCTGGGTGACAGAG
TGAGACTCCATCTAAAAAAAAAAAAAAAAAAAAAAAAAAGAGGTCAGAAGTCGAGACTCCTAAGGTACTTCTCTGGGACCCCCACTCTGGCCAGGGTCCTCGATCTTGGGCTGAATGAGT
GAGCACCCACCCTGGGCTGCCCCAAGCTCACCACTTGGTCTGCTCTTCCTTAGTCTTACACAGTGTGGGCCATGTGGTGAATGTGTACCTGTTCTCCATCAGCCCCCTCAGCGTCCTCTC
TTGCCTCTTTCCTGGCCTCTTCCATGATGATGGGTGAGTAAGTGCGAATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATAATGGGGAGGATTCCTT
TTGGGTGGAAAGAAATTATCTGGCTCCAGAGGAGACTGTCACCTTCTAGGTTACAGGACAGACAGTGACCAGCCTGAGCCCCTAATGCCAAGTCAGCAGGAGAGACTGGTGTCTGAGTTG
GGGTGCCTCCCCTGAAGGGTCCCATCTGGAATTCCCAAAGATCTCCTCTCATTAGCTGGGCATGGTGGTGCGTGCCTGTAATCCCAGCTACTGGGGAGGCTGAGGCAGGAGAATGGCTTG
AAACCAGGAGGTGGAGGTTGCAGTGAGCCAAGATCATGCCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCTGCCTCAAAAAAAAAAAAAAGAGAGAGAGATCTCCTCTCAAGGTGT
CTCTTTGCTGTCCCTTCCACACAGGTCTGAGCTCCCCCAGAAGTATTACTGGTGGTTCTTCCAGACCGTACCAGGTGAGAACCCTCCTTGATCCATGAATTTCTGGACCTGACTGTGAGT
TCAAGGCTCTGGGTTCTCTGCACCCCAGAGCAACCCACGTTCACTCACTCAGCTCTTCCGGTGACCCAGGCTCTGTCCTCTGGCCTGAGGACACTACTGGGTGGGCAGGAGACTTAGACT
ACTCTGCATTCCAGCCCTCCTCGCAGGAGCTCAACTGGGTTCCTGCCCCTACTTTGGGCTAGTTCCTTCTCTAGTAGGGTTAGGAGGAGAAATATCTCCTACTATGGACTAGTTCCAGTG
GAATAGGAGTGGCTGGCTACCTCTTCCCCCAATACACACACATACCCTAACAGTAGCTTTGAGGAGTGCTGTGCCCCAGCTGCATGGGGGAAGGAGCAGGCTCTTTGTCAAGCCAGACAG
AGGCGCCTACCCAGTATGCCTTGAAAGGAGCGTTTGGGGGATATTCCTAACTCCCTATAATCACCCATCTTAGAGCTATTAGCTGTGAATCTATTCAAATTCTCTTGAACCTATTTATAT
TTTCAGTCTGTTCCTTCCTTGGAGTAACATAATTTCTATACTGGCTCCTCTCTGTGAAACACAGCATGGTTTTTTTTTTTTTTTTAATCCTAAAATGATCTGCTTTGAACTTCAGAGGGT
GCTTGCTAATTCCTGCACACTGAGATTTAGTGGATAAGGCTGTGTTTATGCTCTCCTCTCCTTTTAGGACTTTACAGGCTTTGGTTAGATCCCTTCTTAACCTTTACTTTTTTATACTTC
AGGGCTCTAATCTTCTTAACTTCTGCCTCTCTTCCTTGATCACTTGAGGGAGCATTCTCTGTCCTCTCTGCCCTGCCCTGGCTCCAGTATTATCCCCCTGTATACCCATGGCCTGGATCC
CCTGTGAGAGGAGGGGCCTCCCACCAACTCTGGGTTGTACTTGGGGACCCTAGTGATGAGCAGGGACAGTGTGGTCCTGGCCAGTCACTAACAGTGCCAGTGCTCATGCTGTGTGCTGTG
GCAGCCAACAAAGAGTGGTGCAGGGACAAGGACCAAACCTTGACTCGATGAGAGTACAGCCTGTCATTTCCATTGTTTGGCCCAGAGGGCCCAGAGTGGACACCCTCTGCATCCATTCAT
TCAGCACACATTTATATAGGGCCCACGGTGTGCCAGGCCCTTGCACTAGGCACTAGGATTCAGTGGCAAACTAGCTTAGCCTGTTCCTCATTCTTGAGAACCCGAGAGTCAGGAAAGTGA
CAGACAAAAACCAAATAATGACATTGGTGAAAAATTGGCTGGGTGTGGTGGCTCATGCCTGTATTCCCAGCACTTTGGGAGGCCAAGGTGGGCGGATCACCTGAGGCCAGGAGTTCAAGA
CCAGCCTGGCCAACATGGCAGAACCCTGTCTCTACTAAAAATAAAAAAAATTAGCTGGGCATGATGGTGCATGCCTTTAGTTCCAGCTACTCAGGAGGCCGAGGCAGAAGAATCATTTGA
ACCTGGGAGGCAGAGGTTGCAGTGAGCCGAGATTGCACCAATGCACTCCAGGGAGCCTGGGTAACAGAGCAAGACTCCATCTCAAAAAAAAAAAAAAAAAAAATCATGGTGACAAGGGCT
ATGAAAAGTGAACAATGTCTGCTGAAATGAAAGGTACCTGTGATCAGTGGTGTTGGGGGAGAGGACCAGAGGAGAATGCTGGGACATTCTTACTCCAACTTGGGCAGTGGAGTGGAGAGG
GGACCTTGGAAGCTCCAGAACAGTTCCCTTTCAAGGCACTGATCTTCTGCCTTCCACCCTATATTCATTTTGCAGGCCTCACGGGGGTTGTGCTGCTCCTGATCCTGGCCATCATGTATG
TCTTTGCCTCCCACCACTTCCGCCGCCGCAGTTTCCGGGGCTTCTGGCTGACCCACCACCTCTACATCCTGCTCTATGTCCTGGTGAGGGCTTTTGGCTGTGAGCCAGGCCAGGAGGGTA
TGGGCAGGACATTTCCAGGGAGGCAAGGAGAGCTGGGACATTCATTCAATTTCTAGCTATTTGAAGCATCCTCTTCACTTCTCGACGTCCCTCTTTGAAGGTGGAGATGATAGTACAGGG
CTCTCCATTAGGATGACCCCAATATGCAGCACTTGGAAGCTCGGCTCCCTGGCATGGGTTTTGCAGTAGCAGCCCTGCCAGACTGATCTCCATTCCTCGCAGACACCTCCACCCCACTTC
TGCCCAGCTAGTCTTTCCCCACTTTGGGTGGCTGGTTTTGGCTCCTGGGTGGACTACCTGCACCCAAGAGAGCATCACCCTTTTTGAAGAAACTTATCTTAAATGGGTTCTGCCACTTTT
GTTCTGATCCTATTTTTGGGGGCATTAGTCACACCTGCTAAGTGCCACCTGTACAGTATATAAGCTTGTTCAAAATGACTTCAGTTGGATTGTTGATCTAATGAATTTTTATTTTTTATT
TTTTGAGACAGAGTCTCGCCCTGTCGCCCAGGCTGGAGTGCAATGGCATGATCTCAACTCACAGCAACCACCGCCTTCCGGGTTCAAGCAATTCTCCTGTCTCAGCCTCCTGAGTAGCTG
GGACTACAGGCACGCACCACCATGCCTGGCTAATTTTTGTATCTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAATTCCTGACCTCGTGATCCACCCACCTCGGCC
TCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCAGGCCAATCAAATAGATTTTTAAGACTCTACCTATCCCCTTTCCTTCTCCTTAACCTTGGCTCCTGCCTCCCTCTCTCCAT
GTTGCCTCCCTTCTCATGTTCCCTTCACCCTCCCCTGGGTTTCTCATCGGCTGCCTAGCTGGTTAGTTCCCGAGCTGATTCTGTGTCCCTGTGTTGTGGCTCTGCTTGTCTGCCTTCCTC
ATGAGCAGAGGCAATTCCCTAAAGGGTACTCTGAGGGCCTCACTTAGAAGCTAAACCAAATCCCAAGGCTCCAGCTGTTCCCTGCAGCAGAACTGCATACAGGGCTCTCCTTTGTGCCGA
GACAAAGAGAAACTGCACCATGGCCTCGGTCAGGTTGGCTCCTGCCATCTGACCTGCCTTCTCTCAGGTGCAGTTCTGTCCTCACTGACAGATAGGAGGGTCTGTTTCATCTTGCCTGTT
GCTCAGCATTTCACAGTTCTGAAGATGACTACTTAGCCTTGGCTTAGGATGTTTCCTAGAACTGATGATATGCGTTTCCTAAGAAACATCTCTTTCTTTGGAAGCTATGACTAATTTACC
CTCTCTCCTCCTCTTCCCAATAATGAGTGGAGCCCTAGCATTCTCGGCTACTGCTTCTGTTGGGGGTGGAAATGACGTTCTTGTTCCTGGTGATAAAGCAGCTACTTTGAACTAGATGAG
AGATCCAGAAGAGTGGCCAGGCAGGCTCCCTAAGACCCAGAGCCCTTTCTGATTTGTCCTGGGGTGTAGGCATCACTAGGATTCCAAGCCACCCTTCCTGCCAGCAGGAAAGTCAGGGGT
TCGAAAGGTGTGGCCGGGCACAGTGGCTCACATCTGTAATCCAGCACTTTGAGATGCCGAGGTGGGTGGATCACCTGAGGCCAGGAGCTCAAGACCAGCCTGGTCAACATGGCGAAACCT
CGTCTCTACTAAAAATACAAAAATTAGCTGAGTGTGGTGACGCACACCTATAGTCCTAGCTACTCAGGAGGCTGAGGCATGAGAATCGCTTGAACCCAGGAGGTGAAGGTTGCAGTGAGC
CGAGATCATGCCATTACACTCTACCCTGGGCAACAGATGGACAGCCTGTTTAAAAAAAAAAAAAGAAATAAAAAAGGAAAAAAGAAAGGTGGAGGCCTCTATGCTAGGCTATCCTCACCA
GCAGTTTGGGACAATCTCATCTCAGGGAGATCAGGGCAAGAGCACCCTCTTTGTTCCCACTTGTCCCAGGCGTGACCACTTGACTTCAAGCAGAAAGATAAATTACAAGTAAAGGACCCC
AGTATAGACTAGACCCTGGGGAAGGATGGCCAGGCTTCTGATCCAGGCAGAAGAGGGCAGGGCTAGCACATCAGAGGCTGAGCTGGCTGAGCCACCACCCCATCCCACCAGCCAACAAGG
AATCTGCAGCAGCCTTGTGGTTTAAAAGGAAAGCCAGCACAAAATAGGGTGTAGAAACAGAGCAGCATGACGTCACCCTGCCATTGTACTCAGCCTGTTTGGATGCTCAGAAAGCCTTAG
GGGTGGGTGTGGGCTCCACAATGAAACAGTGAACTTGGGGAAGAAAGAGCCAGTTCAAAGAAGAGCTCAGAGAGGTTTAAGTTAGTCTTGTAGGGAAAGGTTCAAGAATCTAGGAAGACT
TAGCTGGGGGAAGGGAACGCCTGAATGGGGAACCAGAGTTCAGTTTAAAAGCTATCTGTTGGCCGAGTGCAGTGGCTCGCACCTGTAATCCCAGCATTTTGGGAGGCTGAGGCGGGTGGA
TTACCTGAGATCAGGAGTTGGAGACCAGTCTGGCCAACATGGTGAAACCCCGTCTCTACAAAAAAATTAGCCGGGAGTGGTGGCATGCGCCTCTAATCCCAGCTACTCGGGAGGCTGAGG
CAGGGGAATTTTTTGAACCAGGGAGGTGGAGGTTGCATTGAGCCAAGATCACACCACTGCACTCCAGCCTGGGTGACAGCGAGACTTCCATCTCAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAGCAGCTATCTGTGTATCTGTGGAGGGTCTTTTATGTACTAGCTCTCTGTAGGGCCCAGCAGCAGAAGGGGAGACTCTAATCTCTTCCTTAGGAACTTAGGATTCGCTGTGACAAAAA
GTGGCACATGCATGAAATGATCAAAATGAACACTTGATATAGGATTAATTGCTGAGCGGAGTGTTCCAAACAGTAAGTTATAGGAGTTCACTGAAGGGAGTTTCACTTGGGCTAAATTGG
CTAGGGAAGACTTTGAGGAGAAGACTGGACTTGGGCCAAGGGTCTGGGGGAGGTAAGCTAAGCTTTGACAGGGCAGAGTGGAAACTGAAGAGCAATCCAGGTAAAAGGAAGGGCATGAGC
ACAGGCAGAGGTGGGAATGGTGATAGGATATTCAGGAGGCAGAGGGGACAGGGCTGGCTGCAGATGGCCATAGGGCATTAGGTGGTGGCAGGACATGCTGCTGGTGATCATGTGGCAGCT
GCAGTTGAAACTGAGGGGCTGTGGCTCAGCTGAGAGGCCATGCCACATGGCGGAGCATAGAAAGAGATGAGCAGAGGGTGACAAAACCAGGCTTGGGCAACACCCATGACTGGGGGTGGC
AGAAGGAATTAAGCCAGTGGAGGAGATGGAAAGCGAGTGGCCCAAAGTGGGAGAACCAGTAGAGCATTGTTGCAGAAGTGGCGAGAAGGAGGTGGTCACTAGTGCCTCAGGCTTCTAAGA
GTAGGAGCCAACATGGCCTGAAAAGATATATTTTACCCATTTGTGGGGCTGCTGGGCCCTCAGTGGGAAGGTCCTAAGGAGAGGTGGACGCAGAAGTCAAACTGAGCCAGACTCAGGAGC
AAGCAAGTGGGAAGAATGTGACCAAGTAGTGTCTGACCATGTTAGACAAACTTATTAGGGAAAGGACCAGAGCTGGATGATACTTGTCAGTTATTACATGGAAAAGGGAGACTAGTTAGG
TATTCTTAGCCTGGAAAAGGAGAGGATAAACTGGGGAAGCGCCTTTCCCCAACAGTTACTGTGTGCCTATCATATGCCAGGCAGAAACTGCTAGGAGCTTATAATGGCAAACAGTCCCTA
CCCCTTCAGTCCAGTGGGGAAAACGACAGTAAACATGTAAATGAATGAGGAAGCAAAAGTACTGTTGGCCGCGCGCGGTGGCTCACACCTGTAATCTCAGCACTTTGGGAGGCCGAGGTG
GGCAAATCATTCGAGGTCAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTATCTGGGTTTGGTGGCAGGTGCCTGTAATCCCAGCTACTCGG
GAGGCTGAGGCAGGAGAATCTCTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCTAAGATCATGCCATTGCACTCCAGCCTGGGTGACAGAATGAGACTCTGTCCCCCCAACCCCCAAAAA
ACAAAAGTACTGTGGATGACAACGCATGCACTAAGAGAGTTAACAGGCAGATGTGGTAGAGAGGACTGAGGGGAGGCCTGAGGAGGTGGTGTTTCTACTGAGACCTGAAAAATGAGATGG
AGCTAGCCATGGGAAGAACCAGGAGAAGGGCATTCCAGGCAGGAGATGCAAAGATCCTTAAGCAGAAAGGACTGGCCGTGTTTGAGGAACAGGGAGGGGAGAACGGCTGGCAGGCAGAAG
TCAAGAGTACTTGTGAGGCCTTGTAGTGCAATGGGAAGGCCACCAAAGCTTTTAAAGCTGGGGATGAACAGGATAAAATGAACTTTAAAAAGTCACACTGGCTGCCTTGAAGAGACAGGA
ATTACAGTGAGACAAGACCAGTAGAAGACCTACTTCCACTGGAAGGCTCCTGCATGAGTCCAGGTGACAGGTGACATCACTTGGTCTAGGGTGGTGTCAGGGATCTAGAAAATACTCTAA
TTCCTCATGGAATGCTATGGAGGATGGAGTTGGGAATGGTGAGGTTTTGCAACCTAGAAGGAGCATGGTACGTGGTGAGGTGGGGGCTGGATATACCAGCGGGGAAGTATGGAGGGTCTA
AGGCCTGAGCTGGCCCTGTATTCTGCTATGGGCATCGCTAGGTCTGAGCAGAGCTCTTTCCTCCATCTAGCTCATCATCCATGGTAGCTTTGCCCTGATCCAGCTGCCCCGTTTCCACAT
CTTCTTCCTGGTCCCAGCAATCATCTATGGGGGCGACAAGCTGGTGAGCCTGAGCCGGAAGAAGGTGGAGATCAGCGTGGTGAAGGCGGAGCTGCTGCCCTCAGGTACCAGCCTGGCAGG
AGATCAGCTTGGTGACACTGAGGGAGCTGACCGGGCAGAGGCAGAGTCTAGACCGCACAGTCTCCTGGTCGGGCCCAGTGGAGCTGGCAGGTGCCTTGGGTGGCAGGGACAAAGGAGCTG
GTAGGGGCAAGGCGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAAGTGGATCATGAGGTCAAGAGATCGAGACCATCCTGGCCAACATGGTGAAACCCTGTCTCT
ACCACAAAAAAAAAATACAAAAATTAGCTGGGTGTGGTGGCATGCACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCGGTTGAACCTGGTAGGCAGAGGTTGCAGTGAGC
TGAGATCGTGCCACTGCACTCCAGCCTGGCAACAGAGTGAGACTGTGTCAAAAAAAAAAAAAAAAAAAAAAAAAGGAAGGAGGGAGGGAGGGAGGGAGGAAGGAAGGAAGGAAAGGAAAG
GAGGGCTGTTTGCCAGGGGACCTGAGCCTCTCTCATCGCAGAGAGCAGAGAAGCTCAGGCCAGGCTGCCCCTTGCCTGGCTGACCCTCAGCCCCAGTGCTGCCTGGGCCCCCACAGGGTG
AGCTTCTGATGGGGGAGGCCTCCTTTGTCATATTCCAGAAGCAGAGCTGAGGCTGTGGGTGGGGAGCTCTCTGGAGGCCACATTGTTGCTGGGTTCAGGGCAGCAGCTTCTCACCCACCA
TCCCTCCCCAGGAGTGACCCACCTGCGGTTCCAGCGGCCCCAGGGCTTTGAGTACAAGTCAGGGCAGTGGGTGCGGATCGCTTGCCTGGCTCTGGGGACCACCGAGTACCACCCCTTCAC
ACTGACCTCTGCGCCCCATGAGGACACGCTTAGCCTGCACATCCGGGCAGCAGGGCCCTGGACCACTCGCCTCAGGGAGATCTACTCAGCCCCGACGGGTGACAGATGTGCCAGATACCC
AAAGGTACCAGACCCTGGCCAGACATGCCACATGCGCCCATATCCCCTTTGAAGGCTTTGGCCCGGCAGCACTAGACTCCCCGCTCTGTGCCTCCCCTCTCTGCATCTAGAGACTGGTTG
TTCCAGATAATGCCACAAATCCTCCTCTTCCCCTCACTCCATATACGTATCTACCTTTCCTTTTCTCTCATTTCTGGCTTCCGATCTATGGTGGTGGCCAAGCTTAACTGAAACCCACGC
CCCTCCCTACAGCTGTACCTTGATGGACCATTTGGAGAGGGCCACCAGGAGTGGCATAAGTTTGAGGTGTCAGTGTTAGTGGGAGGGGGCATTGGGGTCACCCCTTTTGCCTCCATCCTC
AAAGACCTGGTCTTCAAGTCATCCGTCAGCTGCCAAGTGTTCTGTAAGAAGGTGAGTACTGCCCCCACTTCCCACCAACCCATGGCCCCTTCTTCCTTGTCATGGTACCCATCTGTGCCT
TTCTCCTCTGCCTTTGTTCTTGGCTTCCCTGAACTGGGCAGGGGCAAGTTGGTTTGAAACCTGGGGTTGGGTGGTGAGTGGGGTGGTATCAGGATATCCCTAGACCCTTTAGGACAGAAC
TGGTTTGCGGATGCCTCCAGAATCCTGCCTGGTTTACAAAGACTCTTTCCCTCAGTTAGGGGTGCTCCACATAGGATTTGCTTCTGGGAGTTCCTCCAGGCAAGGTTGGAGGGGGTAAAG
AAACCCATTCCTTCTTACAAAGGAGCCCAGCACTTGGAGCCTTATTGGGCTGGGAGAGGGAAGGGCATGTTGGGTGGAGCACAAGTGAAACTGGCTCAGCTCTCAAGAGGAACAGGAGGA
GTGGTGGCAAGGCAGGGCTGGTGGGCCAGGTTGGCCCCAGGAACACAGCTCAAACCCTCAGGCCCTCACACGGGTCCTTTCACACCAGCCTGGACCTGGTGGCAGGCCCCTGCTCGTTTC
TCTGGGCCTGGCAGGTGAGTCAGGGGTGCTGGAATGCAGTGGGCAGAGGCCCAGCCCATGTGCTGTCAGCATTCAGAGGGTGACAGCTCCCCTCCTGTCCTCTGCCCTCTGCTTCTTAAC
TATACAGCCCCGCTTTCCTCCCTCGGAAGCTGCAGAGGGCTCCCCGCAGGGCAGCTTCCACCCGCTGGTATCTCTTTGAGCCCATTCCCATCTGCTCAGGCAGCTGCTGGGTCTCCCTGA
GGCTGCTCTGTGAAATGCCCTTTAGCCACTAGGTGCCTGGCAGCCTGACCAGGGACCACTGGAGGGAGCTGTAGGACAGGCTGAGCATGAAAGCTGCTTCCCACCCCACAGACCATCAGC
TCCCAATCACCAAGGGATCTTTCCCATGGCCCTGGGGTCTCTCACTTCCACCTCTCTATGCCCTGGGCCAACTCCATCTCTGGCCTCAGAGCCTGGCCCCGTGGCCCATACACTCCATCT
CCCCAGGCTGTCTAGGGAAGGGCACAAGCTAGCTGTGGTCAGAAGAGTTCTATCAGTATGGACACCCCTGGGGTTTAGGGAGACTGAGCTGAGATGGGTCCTGAACTCCAGCCCTGTGTC
CCCAGATCTACTTCATCTGGGTGACGCGGACCCAGCGTCAGTTTGAGTGGCTGGCTGACATCATCCGAGAGGTGGAGGAGAATGACCACCAGGACCTGGTGTCTGTGCACATCTACATCA
CCCAGCTGGCTGAGAAGTTCGACCTCAGGACCACTATGCTGGTATGTCAGGGCCCACCAGGAGGGTATGCGGGCCACTGTCTGAGCTAGGAATTGACCCTAGCTGTGCCTGGCTGAACTT
TGTTCCACCCTTCCCTACCATAGTACATCTGTGAGCGGCACTTCCAGAAGGTTCTGAACCGGAGTCTATTCACAGGCCTGCGCTCCATCACCCACTTTGGCCGTCCCCCCTTTGAGCCCT
TCTTCAACTCCCTGCAGGAGGTCCACCCCCAGGTCAGTCCAACCCATAACCAGGTTCTCTTCCTCTTTATCATTTGGGGTCTGAGCAAAGCTCCCAAACCTTCCCCATCGAGGAAGAAAT
CGACTGCTGATGAGAACCCATCCCCTGGGAGATTGGTGGGGTAATGGAATGGAAAGGATAGGTGGGTGTCACCCTTAGGTGCTAAAGGAGGAGGCAGGCAATAGGGACTTGCCATCTCTG
AAGCCAAGATGTATTGTCCAGAAGGAAGAGCTCAATCATTGAGCTAGTCCTCGCCAAAAACTCGGGGCTACCCTCACCACTACCCTCACCAATACTGAGTCAGTCCTCACCCTGGACACT
GAGGGAACCTTTACCATGAGCACTGGGCTAGTCACTACTCACAAATACTGGTCTAGCCCTCCATGAGACCCTGAGCTGTTCTTCAACTTGAACACTGATTAACCCAACCTCTATTAGAAA
TGTTGATCTAGCACTTAGCAAAATTCCACTAGACCTATAAACACTGAGCCAGCCCTCACCATGCATAGTACAAAGCAAACCATCAGGAGCACTGCTGGCTTTTTTTTTTTTTTTAATTTA
AAGAAAGGGTATTGCTCTGTTGCCCAGGCTGTAATGCAGTGATGCAATACCAGTTTACTGTAACCTCCAACTCCTGGGCACAAGCAATCCTCCTGCCTCAGCCTCCCAAGTAGCTGGGAC
TACAGGAGTGCACCACTATGCCTGGCTAATTAAAAATAAAAAAATTAGAGTCAGGGATGTTGCTATGTTGCCCAGGCTGGTCTTGAACTAGGGAGCTACCCCTTCCTCTGAACACTGCGT
TATCCCTGCCTCTGAGCAAAGAGTTAGCCTCCACTTATTCCTCCTGCAACAGGTCCGGAAGATCGGGGTGTTTAGCTGTGGCCCCCCTGGCATGACCAAGAATGTGGAAAAGGCCTGTCA
GCTCATCAACAGGCAGGACCGGACTCACTTCTCCCACCATTATGAGAACTTCTAG

Retrieve as FASTA  
CDS►
Send to BLAST
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
ATGGGCTTCTGCCTGGCTCTAGCATGGACACTTCTGGTTGGGGCATGGACCCCTCTGGGAGCTCAGAACCCCATTTCGTGGGAGGTGCAGCGATTTGATGGGTGGTACAACAACCTCATG
GAGCACAGATGGGGCAGCAAAGGCTCCCGGCTGCAGCGCCTGGTCCCAGCCAGCTATGCAGATGGCGTGTACCAGCCCTTGGGAGAACCCCACCTGCCCAACCCCCGAGACCTTAGCAAC
ACCATCTCAAGGGGCCCTGCAGGGCTGGCCTCCCTGAGAAACCGCACAGTGTTGGGGGTCTTCTTTGGCTATCACGTGCTTTCAGACCTGGTGAGCGTGGAAACTCCCGGCTGCCCCGCC
GAGTTCCTCAACATTCGCATCCCGCCCGGAGACCCCATGTTCGACCCCGACCAGCGCGGGGACGTGGTGCTGCCCTTCCAGAGAAGCCGCTGGGACCCCGAGACCGGACGGAGTCCCAGC
AATCCCCGGGACCCGGCCAACCAGGTGACGGGCTGGCTGGACGGCAGCGCCATCTATGGTTCCTCGCATTCCTGGAGCGACGCGCTGCGGAGCTTCTCCAGGGGACAGCTGGCGTCGGGG
CCCGACCCCGCTTTTCCCCGAGACTCGCAGAACCCCCTGCTCATGTGGGCGGCGCCCGACCCCGCCACCGGGCAGAACGGGCCCCGGGGGCTGTACGCCTTCGGGGCAGAGAGAGGGAAC
CGGGAACCCTTCCTGCAGGCGCTGGGCCTGCTCTGGTTCCGCTACCACAACCTGTGGGCGCAGAGGCTGGCCCGCCAGCACCCAGACTGGGAGGACGAGGAGCTGTTCCAGCACGCACGC
AAGAGGGTCATCGCCACCTACCAGAACATCGCTGTGTATGAGTGGCTGCCCAGCTTCCTGCAGAAAACACTCCCGGAGTATACAGGATACCGGCCATTTCTGGACCCCAGCATCTCCTCA
GAGTTCGTGGCGGCCTCTGAGCAGTTCCTGTCCACCATGGTGCCCCCTGGCGTCTACATGAGAAATGCCAGCTGCCACTTCCAGGGGGTCATCAATCGGAACTCAAGTGTCTCCAGAGCT
CTCCGGGTCTGCAACAGCTACTGGAGCCGTGAGCACCCAAGCCTACAAAGTGCTGAAGATGTGGATGCACTGCTGCTGGGCATGGCCTCCCAGATCGCAGAGCGAGAGGACCATGTGTTG
GTTGAAGATGTGCGGGATTTCTGGCCTGGGCCACTGAAGTTTTCCCGCACAGACCACCTGGCCAGCTGCCTGCAGCGGGGCCGGGATCTGGGCCTGCCCTCTTACACCAAGGCCAGGGCA
GCACTGGGCTTGTCTCCCATTACCCGCTGGCAGGACATCAACCCTGCACTCTCCCGGAGCAATGACACTGTACTGGAGGCCACAGCTGCCCTGTACAACCAGGACTTATCCTGGCTAGAG
CTGCTCCCTGGGGGACTCCTGGAGAGCCACCGGGACCCTGGACCTCTGTTCAGCACCATCGTCCTTGAACAATTTGTGCGGCTACGGGATGGTGACCGCTACTGGTTTGAGAACACCAGG
AATGGGCTGTTCTCCAAGAAGGAGATTGAAGAAATCCGAAATACCACCCTGCAGGACGTGCTGGTCGCTGTTATCAACATTGACCCCAGTGCTCTGCAGCCCAATGTCTTTGTCTGGCAT
AAAGGAGACCCCTGTCCGCAGCCGAGACAGCTCAGCACTGAAGGCCTGCCAGCGTGTGCTCCCTCTGTTGTTCGTGACTATTTTGAGGGCAGTGGATTTGGCTTCGGGGTCACCATCGGG
ACCCTCTGTTGCTTCCCTTTGGTGAGCCTGCTCAGTGCCTGGATTGTTGCCCGGCTCCGGATGAGAAATTTCAAGAGGCTCCAGGGCCAGGACCGCCAGAGCATCGTGTCTGAGAAGCTC
GTGGGAGGCATGGAAGCTTTGGAATGGCAAGGCCACAAGGAGCCCTGCCGGCCCGTGCTTGTGTACCTGCAGCCCGGGCAGATCCGTGTGGTAGATGGCAGGCTCACCGTGCTCCGCACC
ATCCAGCTGCAGCCTCCACAGAAGGTCAACTTCGTCCTGTCCAGCAACCGTGGACGCCGCACTCTGCTGCTCAAGATCCCCAAGGAGTATGACCTGGTGCTGCTGTTTAACTTGGAGGAA
GAGCGGCAGGCGCTGGTGGAAAATCTCCGGGGAGCTCTGAAGGAGAGCGGGTTGAGCATCCAGGAGTGGGAGCTGCGGGAGCAGGAGCTGATGAGAGCAGCTGTGACACGGGAGCAGCGG
AGGCACCTCCTGGAGACCTTTTTCAGGCACCTTTTCTCCCAGGTGCTGGACATCAACCAGGCCGACGCAGGGACCCTGCCCCTGGACTCCTCCCAGAAGGTGCGGGAGGCCCTGACCTGT
GAGCTGAGCAGGGCCGAGTTTGCCGAGTCCCTGGGCCTCAAGCCCCAGGACATGTTTGTGGAGTCCATGTTCTCTCTGGCTGACAAGGATGGCAATGGCTACCTGTCCTTCCGAGAGTTC
CTGGACATCCTGGTGGTCTTCATGAAAGGCTCTCCTGAGGAAAAGTCTCGCCTTATGTTCCGCATGTACGACTTTGATGGGAATGGCCTCATTTCCAAGGATGAGTTCATCAGGATGCTG
AGATCCTTCATCGAGATCTCCAACAACTGCCTGTCCAAGGCCCAGCTGGCTGAGGTGGTGGAGTCCATGTTCCGGGAGTCGGGATTCCAGGACAAGGAGGAACTGACATGGGAAGATTTT
CACTTCATGCTGCGGGACCACAATAGCGAGCTCCGCTTCACGCAGCTCTGTGTCAAAGGGGTGGAGGTGCCTGAAGTCATCAAGGACCTCTGCCGGCGAGCCTCCTACATCAGCCAGGAT
ATGATCTGTCCCTCTCCCAGAGTGAGTGCCCGCTGTTCCCGCAGCGACATTGAGACTGAGTTGACACCTCAGAGACTGCAGTGCCCCATGGACACAGACCCTCCCCAGGAGATTCGGCGG
AGGTTTGGCAAGAAGGTAACGTCATTCCAGCCCTTGCTGTTCACTGAGGCGCACCGAGAGAAGTTCCAACGCAGCTGTCTCCACCAGACGGTGCAACAGTTCAAGCGCTTCATTGAGAAC
TACCGGCGCCACATCGGCTGCGTGGCCGTGTTCTACGCCATCGCTGGGGGGCTTTTCCTGGAGAGGGCCTACTACTACGCCTTTGCCGCACATCACACGGGCATCACAGACACCACCCGC
GTGGGAATCATCCTGTCGCGGGGCACAGCAGCCAGCATCTCTTTCATGTTCTCCTACATCTTGCTCACCATGTGCCGCAACCTCATCACCTTCCTGCGAGAAACCTTCCTCAACCGCTAC
GTGCCCTTCGACGCCGCCGTGGACTTCCATCGCCTCATTGCCTCCACCGCCATCGTCCTCACAGTCTTACACAGTGTGGGCCATGTGGTGAATGTGTACCTGTTCTCCATCAGCCCCCTC
AGCGTCCTCTCTTGCCTCTTTCCTGGCCTCTTCCATGATGATGGGTCTGAGCTCCCCCAGAAGTATTACTGGTGGTTCTTCCAGACCGTACCAGGCCTCACGGGGGTTGTGCTGCTCCTG
ATCCTGGCCATCATGTATGTCTTTGCCTCCCACCACTTCCGCCGCCGCAGTTTCCGGGGCTTCTGGCTGACCCACCACCTCTACATCCTGCTCTATGTCCTGCTCATCATCCATGGTAGC
TTTGCCCTGATCCAGCTGCCCCGTTTCCACATCTTCTTCCTGGTCCCAGCAATCATCTATGGGGGCGACAAGCTGGTGAGCCTGAGCCGGAAGAAGGTGGAGATCAGCGTGGTGAAGGCG
GAGCTGCTGCCCTCAGGAGTGACCCACCTGCGGTTCCAGCGGCCCCAGGGCTTTGAGTACAAGTCAGGGCAGTGGGTGCGGATCGCTTGCCTGGCTCTGGGGACCACCGAGTACCACCCC
TTCACACTGACCTCTGCGCCCCATGAGGACACGCTTAGCCTGCACATCCGGGCAGCAGGGCCCTGGACCACTCGCCTCAGGGAGATCTACTCAGCCCCGACGGGTGACAGATGTGCCAGA
TACCCAAAGCTGTACCTTGATGGACCATTTGGAGAGGGCCACCAGGAGTGGCATAAGTTTGAGGTGTCAGTGTTAGTGGGAGGGGGCATTGGGGTCACCCCTTTTGCCTCCATCCTCAAA
GACCTGGTCTTCAAGTCATCCGTCAGCTGCCAAGTGTTCTGTAAGAAGATCTACTTCATCTGGGTGACGCGGACCCAGCGTCAGTTTGAGTGGCTGGCTGACATCATCCGAGAGGTGGAG
GAGAATGACCACCAGGACCTGGTGTCTGTGCACATCTACATCACCCAGCTGGCTGAGAAGTTCGACCTCAGGACCACTATGCTGTACATCTGTGAGCGGCACTTCCAGAAGGTTCTGAAC
CGGAGTCTATTCACAGGCCTGCGCTCCATCACCCACTTTGGCCGTCCCCCCTTTGAGCCCTTCTTCAACTCCCTGCAGGAGGTCCACCCCCAGGTCCGGAAGATCGGGGTGTTTAGCTGT
GGCCCCCCTGGCATGACCAAGAATGTGGAAAAGGCCTGTCAGCTCATCAACAGGCAGGACCGGACTCACTTCTCCCACCATTATGAGAACTTCTAG

Retrieve as FASTA