Entry information : MmDuOx01 ( DUOX1/Duox2/ LNOX1/ LNOX2/ THOX1/ THOX2/ NOXEF1/ NOXEF2)
Entry ID 3342
Creation 2006-07-18 (Christophe Dunand)
Last sequence changes 2016-02-16 (Christophe Dunand)
Sequence status complete
Reviewer Achraf Jemmat
Last annotation changes 2016-02-16 (Achraf Jemmat)
Peroxidase information: MmDuOx01 ( DUOX1/Duox2/ LNOX1/ LNOX2/ THOX1/ THOX2/ NOXEF1/ NOXEF2)
Name (synonym) MmDuOx01 ( DUOX1/Duox2/ LNOX1/ LNOX2/ THOX1/ THOX2/ NOXEF1/ NOXEF2)
Class Dual oxidase    [Orthogroup: DuOx001]
Taxonomy Eukaryota Metazoa Chordata Mammalia Muridae Mus
Organism Mus musculus (house mouse)    [TaxId: 10090 ]
Cellular localisation N/D
Tissue type N/D
Inducer N/D
Repressor N/D
Best BLASTp hits
Perox score E-value MmDuOx01
start..stop
S start..stop
RnoDuOx01 3109 0 1..1551 1..1551
PtroDuOx01 2891 0 1..1551 1..1551
HsDuOx01 2884 0 1..1551 1..1551
SscDuOx01 2870 0 1..1551 1..1553
Gene structure Fichierperl './assets/cgi-bin/draw_exon.pl' '3342' 'join(1893..1950,4109..4192,4578..4742,5627..5814,5977..6178,6333..6499,6900..6960,7052..7148,9410..9500,10219..10321,10542..10714,12173..12348,12609..12727,13269..13406,14050..14163,14880..15079,15732..15917,19201..19426,19592..19685,19893..20068,22026..22095,22480..22605,23442..23620,23779..24009,24507..24606,24815..24864,26265..26392,30255..30408,30769..31001,31232..31390,32438..32593,32688..32816,33460..33582)' Exons
ExonStart..EndSize ExonStart..EndSize ExonStart..EndSize ExonStart..EndSize
N° 1 1893..1950 56 N° 2 4109..4192 82 N° 3 4578..4742 163 N° 4 5627..5814 186
N° 5 5977..6178 200 N° 6 6333..6499 165 N° 7 6900..6960 59 N° 8 7052..7148 95
N° 9 9410..9500 89 N° 10 10219..10321 101 N° 11 10542..10714 171 N° 12 12173..12348 174
N° 13 12609..12727 117 N° 14 13269..13406 136 N° 15 14050..14163 112 N° 16 14880..15079 198
N° 17 15732..15917 184 N° 18 19201..19426 224 N° 19 19592..19685 92 N° 20 19893..20068 174
N° 21 22026..22095 68 N° 22 22480..22605 124 N° 23 23442..23620 177 N° 24 23779..24009 229
N° 25 24507..24606 98 N° 26 24815..24864 48 N° 27 26265..26392 126 N° 28 30255..30408 152
N° 29 30769..31001 231 N° 30 31232..31390 157 N° 31 32438..32593 154 N° 32 32688..32816 127
N° 33 33460..33582 121  
join(1893..1950,4109..4192,4578..4742,5627..5814,5977..6178,6333..6499,6900..696 0,7052..7148,9410..9500,10219..10321,10542..10714,12173..12348,12609..12727,1326 9..13406,14050..14163,14880..15079,15732..15917,19201..19426,19592..19685,19893. .20068,22026..22095,22480..22605,23442..23620,23779..24009,24507..24606,24815..2 4864,26265..26392,30255..30408,30769..31001,31232..31390,32438..32593,32688..328 16,33460..33582)


exon

Literature and cross-references MmDuOx01 ( DUOX1/Duox2/ LNOX1/ LNOX2/ THOX1/ THOX2/ NOXEF1/ NOXEF2)
Literature REFERENCE 1 Cheret,C., Gervais,A., Lelli,A., Colin,C., Amar,L., Ravassard,P., Mallet,J., Cumano,A., Krause,K.H. and Mallat,M. Neurotoxic activation of microglia is promoted by a nox1-dependent NADPH oxidase. J. Neurosci. 28 (46), 12039-12051 (2008)

REFERENCE 2 Rigutto,S., Hoste,C., Dumont,J.E., Corvilain,B., Miot,F. and De Deken,X. Duox1 is the main source of hydrogen peroxide in the rat thyroid cell line PCCl3. Exp. Cell Res. 313 (18), 3892-3901 (2007).
Protein ref. UniProtKB:   Q8BZ02 [3' end]
DNA ref. GenBank:   NC_000068.7 (122313811..122349226)
mRNA ref. GenBank:   AK037033.1
Cluster/Prediction ref. Genebank:   99439 UniGene:   Mm.108582
Protein sequence: MmDuOx01 ( DUOX1/Duox2/ LNOX1/ LNOX2/ THOX1/ THOX2/ NOXEF1/ NOXEF2)
Sequence Properties
first value : protein
second value (mature protein)
Length (aa):   %s   1551 (1530)
PWM (Da):   %s   176872.36 (174737.2) Transmb domain:   %s   o594-616i1044-1066o1081-1103i1149-1171o1186-1208i1221-1243o (o573-595i1023-1045o1060-1082i1128-1150o1165-1187i1200-1222o)
PI (pH):   %s   8.56 (8.56) Peptide Signal:   %s   cut: 22 range:22-1551
Sequence
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Send to Peroxiscan
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
MGFHLALAWILLVGTLASLGAQNSISWEVQRFDGWYNNLMEHRWG
SK
GSRLQRLVPASYADGVYQPLKEPYLPNPRHLSNRVMRGSAGQPSLRNRTVLGVFFGYHVLSDLVSVETPGCPAEFLNIYIPHGDPVFDPDKRGNVVLPFQR
SRWDRNTGQSPSNPRD
SNQVTGWLDGSAIYGSSHSWSDTLRSFSGGQLASGPDPAFPSDSQSSLLMWMAPDPSTGQGGPRGVYAFGAQRGNREPFLQALGLLWFRYHNLCARKLAQEHPH
WGDEELFQHARKRVIATY
NIAMYEWLPSFLKQTPPEYPGYRPFLDPSISPEFVVASEQFLSTMVPSGVYMRNASCHFQGIPSHNSSVSGALRVCNSYWSREHPKLQRAEDVDALLLGMAS
QIAEREDHVVVEDM
DFWPGPLKFSRTDYLASCLQRGRDLGLPSYTKAREALGLSPISHWQDINPALSRSNGTVLEATAALYNQDLSRLELLPGGLLESHGDPGPLFSTIVLDQFVRLRDG
DRYWFENTR
GLFSKEEIAEIRNTSLRDILVAVTNVDPSALQPNVFFWLGDPCPQPSQLSAKGLPACAPLFIRDYFEGSGFGFGLTIGTLCCFPLVSLLSAWIVARLRKRNFKRLQRQDRQ
SIMSEKLVGGVE
ALEWQGRNEPCRPVLVHLQPGQIRVVDGRLTVLRTIQLRPPQQVNLILSSNRGRRTLLLKIPKEYDLVLLFNMEEERQALVENVRGALKENGLSFQEWELREQELMRA
AVTRQQRGHLLETFFRHLFS
QVLDINQADAGTLPLDSSTKVREALTCELSRAEFADSLGLKPQDMFVESMFSLADKDGNGYLSFREFLDILVVFMGSPEEKSRLMFRMYDFDGNGLISKD
EFIRML
RSFIEISNNCLSKAQLAEVVESMFRESGFQDKEELTWEDFHFMLRDHDSDLRFTQLCVGVEVPEVIKNLCRRASYISQEKICPSPRMSAHCARNNMKTASSPQRLQCPMDTDPP
QEIRRRFGK
KVTSFQPLLFTEAHREKFQRSRRHQTVQQFKRFIENYRRHIGCVAVFYTITGALFLERAYYAFAAHHSGITDTTRVGIILSRGTAASISFMFSYILLTMCRNLITFLRETF
LNRYIPFDAAVDFHRLIASTAIILT
VLHSAGHVVNVYLFSISPLSVLSCLFPGLFHDDGSEFPQKYYWWFFQTVGLTGVLLLLALAIMYVFASHHFRRRSFRGFWLTHHLYIFLYILIIH
GSFALIQMPRFHIFFLVPAIIYVGDKLVSLSRKKVEISVVKAELLPS
GVTHLRFQRPQGFEYKSGQWVRIACLALGTTEYHPFTLTSAPHEDTLSLHIRAAGPWTTRLREIYSPPTGDTC
ARYP
LYLDGPFGEGHQEWHKFEVSVLVGGGIGVTPFASILKDLVFKSSVSCQVFCKKIYFIWVTRTQRQFEWLADIIREVEENDRQDLVSVHIYITQLAEKFDLRTTMLYICERHFQKVL
NRSLFTGLRSITHFGRPPFEPFFNSLQEVHPQ
VRKIGVFSCGPPGMTKNVEKACQLINRQDRTHFSHHYENF*

Retrieve as FASTA  
Remarks omplete sequence from genomic (Chromo 2, 32 introns), mRNA and 28 ESTs.
DNA
Send to BLAST
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
ATGGGGTTCCACTTAGCTCTGGCCTGGATTCTCCTGGTTGGGACACTGGCTTCTTTGGGGGTGAGTATTAGAGTTGCAGAGGAACCAAGGTCTTTTGGTCTTTTCCAAAGACATGCCAAT
CATTTCTGCACCCTCAAGCAGATATAATACCCTGTATATACCAGGTGCTTGTTTCAAGCTATTGAGCAAATGGGTAGACAATAGAATGAAAATGGTTTTTTCTGGTGTGGGTCCCTTTCT
CTCTCCTCTGTCTTCTATCCTGTTTTGTGAGGTAAGTTCTCCTGATGTGAAATAGGAAAGACTGAGTAGACACTTAAGACAGTAAAGCTTCCTGAAGTAAGCTGAAAAGGACTCACCAGT
GTTTTTAAAATAAAATGATCTTGGAACAGGGGATACTATTTGGTGATAGAGCACTTGCCCAGCACATATGAGGCCCTAGGTTTCACCCCCAGTGTTGAATAAAAAAAAAAAAGCACAAGA
TAAGATAATAGCATCAGAGCACAGCAATTCCAGCTTTGGAAGTCTGAAGAGCTTTAGAATCGGTGGGTATTCGCTGTCGTGTAGGGCTCTGAAGAGGAAAGTGGCCGCATGATATTAAGG
TTAGGTTTAGAAAAGCAAGCTTCTATCCAGGTATAGTGGCTCTGCCAGCACTTTGGAGGTAGAGGCAAGAGGATCAATAATTTAAGGTCGTCTTCCAGTAGATGAGTTCAAGGTCAGTCT
GGGCTTGAGACTTTAAGACTGTCTCAAAACAAACAAGCAACAGCAAACCTTGAAAGTCTTTTGCATCTTGGAAGATGATAAATGAAGATGACCCTTCTGGCTGGCAACGGCGAGATAGTG
ATATGAACCCTACACTTCTCCCTTGCCAAAGACGCCCACGGTTCAGTTCTTTCCAGTACTTTCCCTTCCTGGGGCTTCATTTTCTGTCCCAGTTGGTACCTCTTATGCCCAAGATATACT
TTCTCCAAAGGCTACTCCTGCCCTTGACCTGCTTCAGTTCATTTTATTTTGGAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTCTTACTGCCCTAGATCC
TTAGCCAGGTGAAGCCACTTTCCTTCCTGATGGATGTATGTGCACCTTCATGTGTCAGTGAGGGCACATGTCACCCACAACTTGAAAATCCTATCTTTGGTCTAAGGACATTCAGAGCAA
TGGGGCCCCTCTTACTTTCTTCTCTTCTCTCAGTTGAGTAGAAAAGAAGTCTTCTAGTTGTTTTTTAGAGGGGCGTGTTTGGCTGGTCACCTGATCTACTAACCAAGAGGATTCCAGACC
CTTCCTTCTATCCTGCGTTCTCAGCAACCCCCTCCCCCAACAGCTGAGTGTCCCTCTTGGGCTGTGAGTTTTTAGAGCAGCATCATAAACAGGAATTGGGGTTGGAGAGAAGGCTCAGCA
GTTAAGAGCACTGGCTGGCTAGAGGACCTGGGTTCAGTTCCCAGTATTGGCGTGGCAGCTCATAAATGTCCCTAACTCCAGTTCCAAGGGGTCAATAGCCCCTGTGCACATCAGGCATGC
ATGTGGTACTTCGGCATACATGCATGCAAAACACCCATACACATGAAATAAATAAATCTTAAAGAAAGAAAGGAAGGAAGGAATGAGATGAGTGACAAAATGTTCCAATGGAGGACGGAT
TCAGTCATTCACAGAATCAGTCCTTAGTCTCACCCAAGAAACTGGCAAAAAGACCAGAGTAGCAGTGACACGCCCCTGCCTTGGGGCTCTGCTTAGTGGGAAAGAGCCAATCCCCTCTTC
ACATTGCCCCTGCCCAGTGACAGGTCACAGAATGACTTGGCCTTCCTAGTTATAGGGTGTGGCTGGCTCTTGTTCCAAGTGGTAGCTATCCGACAGCTGGGAATGACGTTTGTCCTGGTG
TGCCTCTGGAGGACTTGAGATGTGAGGAGACTCCAGGCTTCTGCATCCTCTACTGGATTGTCACTGTTTTCTCTCCTCTCAGCTAAGACTGTTTGTCAGCAGGCACTGCACGCTCATGCA
CCATGTTCCACTTTAGGAGTCTTCCTCACTGGGTGCCTTGAAGAATAGGCTTGAGTTTAGAAAATACTTTGCCCTTGTTTCTCCCCCTTATTGGAAATCACAGGACCCGTTCCCTCATGG
CCTGCTTGGTCTCCCCTGCACCCACTTGCCCAGTTACCTTTCCTCTGTCTTCACACAGGAGCTCAGAACTCCATTTCTTGGGAGGTACAGCGATTTGATGGATGGTATAACAACCTCATG
GAGCACAGATGGGGCAGCAAAG
AGGTAGGTGAGAGCACAGCCCAAGGGCCAGGGCGGTACTCACCAGTGGAGAGTCAGGGCTGGCAAGTATCACAAGAGGCTATCTCAAGTATCACCAAA
GGCTGCCAACATCTAAGGCTTTAGAGTTCAGTGTATGGAGGGACAGAAGAGGACAAGAACGCACTTGAGGTACAGACATTGCTAAGTGGTTAAGAGTACATGCTGCTCTTACCGAAGACA
CAAGTTCAGATCCCTGCATCCATTTCCAGTGACTCATTGTTACCTGGAACTCGGGGTCTAGGTGTTCTGATGCCTCTGGTCTCTGCAGGCTCATACACTCTCATTCACAGACACACAGAC
AAACACTCACAATTGAAATTCATCCTTGTCTTTACCTCTCCTATGCCAGGCTCTCGGCTGCAGCGCCTTGTTCCAGCCAGCTATGCAGATGGTGTCTACCAGCCCCTGAAAGAACCCTAC
CTGCCTAACCCCCGACACCTTAGTAACAGGGTCATGAGAGGTTCTGCAGGGCAGCCATCTCTTCGGAACCGTACAGTCCTGGGTGTCTTCTTTG
TGGTGAGAGCTGTAGTGGTTGGGGGG
TGGTTCTGATGTTTTGATTGGGAAACTGAGTTTACACGTGGGAATGGTCGGCCAGGAACAAAAGCAATATAAACAAAACTACTTGCTACAGCAAACCTCAGCCCTTGGGGGAGCTTAGCC
AGTGGGAGTCAGATGGACATTTCTGCATCTAAGGACTCAGGGGATGAGAAAAGATACTAAGGAGGATCAAAGATGGGGGTGAGAGATGGAAGAGGAAGCCATTAAAAAGGATAGGAGTAA
AGCAGGTGGGGGCAGGGCATGCTGAAGTGAGGTCTGACAGGCATGAATCTACCTTGTGCTGGTAGGGCGTCCTCCATTTGGGGGGAGGGTTGGGGTACAGACTTGATAAACTGTCCCTAG
GACACTGATGCTCCTAGAACATACCAAGAGAAGAGTCCTAGCTGCGGCAGAGAGGGCAATATGGGGGCCTTATGGTGTCATAAGCTCAGTGACAAGGGGTCCTGCCGCAATGATGGCTCC
TACAGGCCATGTTGGGTGTCCATGCTAGCTCACATGTGACTTCCTGCTTGGCTACAGGCCTTCAGGGAGGCTCCTAGCTGCATGTTGGAGCTGGTGCCCACAACCCTGCCTACTGAGGCG
TCATCTCTGAACACCTCCCAGTTACCAAGGAGAATGCCAAACTGACAATGACAACATCTTAGAGCAGGTGTAGGCACAGGCAGGCCAAGAGAGACAGAACCAGGAGGGAATGTGGAGGTC
AGGGCTTGGATTTGCCCATAATAGGAAATGACTGTTCTGAAGCTTCGAGTAGGGGGCGGGCGTGTCAGGGACTCCATACCTGAGGCAGGGATGAGCATGGCCGTAGGCTGGCCCAGCAAA
CCCTCCTGCATTGTGGGCAGGCTACCACGTGCTCTCAGACCTGGTGAGTGTGGAAACACCAGGCTGCCCCGCAGAGTTCCTCAACATTTACATCCCGCATGGGGACCCGGTGTTCGACCC
TGACAAGCGCGGGAACGTGGTGCTGCCCTTTCAAAGGAGCCGCTGGGACCGCAACACTGGACAGAGCCCCAGCAACCCCCGGGACCAG
AGGTGAGGCCAGGCAGCCAAAGGCAGGAGGGC
AGAGAGGCGGGAAGGGGGTCTGAGGCTGGATCCGCTGGAGGCCTGGGATCTGGCTGGGAAGACCAGACACGATGAGGCTCTCCCTACCAGCAAGGACCTGCCTGGTCCTCCTGACTCTGC
TCATCCCTGCAGAGCAACCAGGTGACCGGCTGGCTAGATGGCAGCGCCATCTATGGCTCCTCTCATTCCTGGAGTGACACTCTGAGGAGCTTCTCTGGAGGACAGCTGGCTTCTGGGCCT
GACCCTGCTTTCCCATCGGACTCCCAGAGCTCTCTGCTCATGTGGATGGCGCCGGACCCCTCCACAGGGCAGGGAGGGCCACGGGGGGTGTATG
TGGTGAGACTGCGGGGTCCTGGTAGG
AGGGGTAGGGTTAGAGGCACCAGGCTGCTTTGGGGTCCTGTACTGGAGAAGGGGCAACTGACTGTGGGTCTGGGCTCCCCTGACTCAAGCTGTTGTCCATCTCCTGTCCTGCTTCCCCAC
ATGGATGCAGCCTTCGGGGCCCAGCGCGGGAACAGGGAGCCCTTTCTGCAGGCTCTGGGCTTGTTGTGGTTTCGCTACCACAACCTGTGTGCCAGGAAGCTGGCGCAGGAGCACCCGCAC
TGGGGGGATGAGGAACTGTTCCAGCATGCTCGCAAGAGGGTCATTGCCACCTACCAG
AGGTGAGTCGTGCCGCCTGCCTGGAGTCCACCTGTGTGTAGGGTCCAAAGAGACTCTGCACCC
CCAACAAAGCTTCCAGGATCCTGGACAACGCCCCTTTCCTACCTAGCCCTTTCCAGGAGGGCTCTTCTCCAGGGAGAGCTAGTATCTAGGAAAAACTACTATATATGATATAGAGGCAAA
AATGGGTTTATGCCAGATTATTTGGGAATTGATCATTACTTAACATCTCTTTCTTCTCAGTAAGTTCTATGAAGAGCCTAGCACTTGATGCTGTTGTTTTGAAGGCCTTTTCTCCCATGA
CCAGCCTTTGCTGGTCCTCGTGTCTACCTGTAAGCCTTCCCTGGGCCCCTTCCTCAGGGCTAGTCCTACACACGTGCCTTTTTACCTTTTGATCCTCAGAACATTGCGATGTATGAGTGG
CTGCCCAGCTTCCTGAAGCAAACTCCTCCGGAGTATCCAG
AGGTGAGGAGGTGGGAAGGAGGGCTGAGAAATTGTGAAGTGTCTTTTAGTGTGGATTTAAACCTTCATGTGTCTGTTTCT
CCTCTTACCTCAGGATACCGTCCATTTCTGGACCCCAGTATCTCCCCAGAGTTCGTTGTGGCCTCTGAGCAGTTCCTCTCTACCATGGTGCCCTCTGGGGTCTACATGAGAGGTAGGAGA
GGAAGCTCACATATTTGTATCTTGGACTCATTATTGATAAAAATCTGCCTTCAGGAGTTCTCAGGACAGGATTACATCAATTCAGAGCAGCTAGTTTCTAGAGAGAATGGTGAAAATGGA
GGGAAAAGGTGGTCTGTTTTTAAATAGACCATTCATTGTGCATGGCGTTGGTTATCCATGATCATGTGATTTGCTTGTATGTGTTTGGTCAATGGCTTTTCAAGATAGGACTATGTAGCC
CTGGCTGGCCTGGAACTTGTCAAGATCCTCCTGCCTTTGCCTCCCATGTAGCTTGACTACAGAAGTACACCTTTGACGGATTAAAAGAAAAAAATGTTTATGGTCTTTAAAAATGTGTAT
ATGTGTATGTAGCTGGGTGGTGGCTCACACAATTTTTTGTTTTGTTTTGTTTTTTTTTTTGAGACAGGGTTTCTCAGTATAACCAGGCCTGACCTTCCTGGACTCCTTTTGTTGACTAGG
CTGCCCTTAAACTCATAGATATCCACCTGCCTCTGCTTCCAGGGTGCTGGGATGAAAGGCACGTGCCACCGTGGGAGGCTGTAGTTCAGATCTTTAATCCCAGAACTCAGGAGGCAGAGG
CAGGCAGATCTCTGAGTTCAAGGCCAGGCTGGTCCATAGAATGAGTTCTAGGACAGCCAGGGCTGAAGAAAACCTATCTCAAATAAAAACAAAACCACTCCACAAAACCAAACAACAACA
ACAAGAAACAAAAAACCCATTAAACCAACAAAAACAATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATGTAGTTGCTTCCAGCCGCTCACGTCCTTAAAGTT
TTTTCACCTGCTTGGGAGGCTGATGTGGGAGAATTAGCTTGAGCTCAGAAGGCAAATGGAAAACTTCATCTTGAAAAAAAAGGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAAGTGCATG
TTTATAGTCTCTAGTCCCAGCAGGTAAGAGTCAGGAGAATAGGAGTTCAAGGTTATTCTTTACTACACAGAGAATTCAAGACCAGTCTGGGTTACTTGAGACCCTCTCTCAAATAGAGAC
TACACATACATATAAATAGAATTCTATAGGTGATAGGTACATAATACAAGTGTGTGTAAGTGTGTAATCTATATAAGTAAGCTATTACATGTCAGGCTTCCTATCTACCCAGTCAAACTC
AGATTTTAAGTATCTGAAAACGTAGATGTTTTAGAGCCATTCTTCCTGAAATAATAAACTCTAGTGACTATTTAGATAGCATTTATGTTATATCAAGTATTATAAGAATATGGGTTGGGG
AGGTAGCGCAGTTAGTAAAGTACTTGCCACTCAGGCACAAGGACTTGAGTTCAAGGGTTCAAGTTCTAGCATCCTATAGGAAGTCAGATGTAGTGATTCTGGCTTGTAATTCCAGTGCTG
AGATGGTAGAGACAGGTAGATCCCTTGGGCTGGCTGGTTTGTCAGTCCAGCTTAATTGTCCCAGGTCCCAGTGAAAGACTCTCAAAGCAAGCAAGCAAGCAAGCAAGCAAGCAAGCAAGC
AAGCAAGCAAGCAAGCAAGCAAGCAAACAAACCAACCAAGGTGGAGAACTTCCAAGGACTGACACCTGAGCATAACTTTTGGACTCCACATGTACCTGCACCCATATCACACACACACAC
ACACACACACACACACACACACACACACACACACACACACACACACACACACACACACGTGCGCGCGCGTGTGTGTGTGTGTGTGTGTGTATGTAAAAACATCCAAAGACTTGGATATTA
CTGTATGGACTAATGTGCATAGATTATAGGCAAATATTATGCCATTTTAGATAAAAGATCTATATATCCATGGATTTGTTATTGGTGAGGGTCTTAGAACCAGTCTCCAGTGTCCTCCAA
AGGACTCCTATCTGTGTGTGAGACTGCTTTCTTTCTGTGTGTTCTTATCCACGTGGAGACAGTGTGGATAGAATTTTTTTAATGGCCAAATTTTCAGATGTGTGATCAGATGGGAGGTAG
GAATCTTCTGAAAGTCAAATTATTCAATAGCTATCAAGGTCTTGATTACACAGCAGATAAGGGAGGCTTATGGCCTGGGACCCCTGGCTGATTACAAAGCAGATAAGGGAGGTTATGGCC
TGGGACCCCTGGCTGAAGTCTTACAAACCAAAGCTGACGCCTGACATTAGGATCCTGTGGTCTCTGTAACCATTCTTGCTCCTTGCACTTTAGGAATGCCAGTTGTCATTTCCAGGGGAT
TCCCAGTCATAACTCAAGTGTCTCTGGAGCTCTCCGGGTCTGCAACAGCTACTGGAGTCGAGAG
AGGTCAGAGTTGGAGATACTATTGGATTGATAAATGCATGTGTTGTATATGTTGCA
TGTGTATATATCTGAGTGTGTGAAGGGGGTGGGCACTAGGGCTGAAGTAGCAGCTCGGATGGGTTAGAGAGTGGGGAACAGCTTGGGGACATGATCAAAAGTCAACTCCCTATCCTCAGC
CAAGGGCTGCATATGAGAGACAGGAGGGGAGGGGGACTGTGTGTTCAGGTGTGCTTCCACATTTACTGTTCTTCTTAGGTGTCTCCCTTGACAACTCTGGGCCCCTGGAGACTTTGGAGC
ACCCAGCTAAGCTATCCCACCTAGACAATTGTCTATACACCCCTAGCTTGGGCCTCTCTTCTAGTAAAAGGAGAGCAGCAAGTTCAGACAGGCCCTATGGCTTCTGCAGGACCACACCAC
TGGTTGATGGGAGAGCAAAAATGAGCATCTAGATGCTCTAGTGTCCTTGCTAGTCATATGGTCAAATCTCCTGGGAAAGAATAAAAGTTAAAACAATAAAAAATAAAATAAACCCTGTGC
TCCAACACATCGGTTTTGGGTGGGCATATCATTTACCATGAGTGCAGAATTAGCCTGAAGTTGAGAAACGCTCACCAGGGGCTAAGAACATGACAAGCCCAGGATGTGGCACAAGTGGCA
GAGGGAGCCAGGAGCCCAAACCCTGGTCCTGTTAGCCATGTCTGTCTTCTCACCACTCCTTAAGCACCCCAAGCTACAAAGGGCTGAAGATGTGGATGCACTGCTGCTGGGCATGGCCTC
CCAGATTGCTGAGAGAGAGGACCACGTGGTGGTTGAGGACATGCAAG
AGGTGAGCCTGAGGCTGGCCCTGCAGGCTGTGAACTTCTGACCGCTGGGAGGAGATCCTGCTGAACCTGCAGA
AGCAGGCAGGGAGGAGTTCTCAGGGCTGAGAGAATCTCTGATCCTCGAATCATGGTTCAGATATTTCTGGGATTGGTTAGAATGGTCTGGGCTGGAGGCTGCAGTGATGGCCCTCAACTC
CCTCTAACTCTTTAGTGTTTCTTTTTCAGATTTCTGGCCTGGGCCACTGAAGTTTTCCCGTACAGACTACCTGGCCAGCTGCCTGCAGAGGGGCCGGGATCTAGGCCTGCCTTCTTACAC
CAAAGCCAGGGAGGCACTGGGCCTGTCTCCCATTTCCCACTGGCAGGACATCAACCCTGCACTCTCCAGGAGCAATGGCACT
CTGTGAGGAAGGGTCAGGACCCAGAGGGCTGGGGAGGG
GCTGGGCACACTGCCCAAACAGGGGAAGGTGGGTAGTAAAACATGGGTGCCAGAGTCTAACACTTGGTGAGAGGACAAAACTCACGCAGGTCACGTTTTTCAGTCTTAATTTGTTCCTAA
GTCAAGGACCTGCAATGTCCACTATAGGATTGTTAAGAGTAACAAAATCAATGTCTACCAAGTTAAGTGTGTGGCAAGCAACAGGTAGTTAATACATATTTACTGGACCTGGGCCTTCAG
AGTCAAAGGGCAAACCCTGCTGGACTTGGAATCTCTTAACTTGGTGTACAAGTTATAAACTTGTAAAGCCTACAGAAACATAGGGATTGTGAGAAAAGTCAATAGGAAGTCTTTGGCTTC
AGTTAGGTGTCATTGGAACGAGCCTGGTCAGGGACTTAGGGACAAGTAAAGAACAGGAGGTGTTAAGATGACTCGGCTGGCATTTGCAGCCAAGCCTGACAACCCGAGTTTGATCCCCTG
CAGAATCCTCATGGTGGAAGGGGTAAACTAATTCCTTAAAGTTATCCTCTGGTCTCTACATGTGCACGTAGTGTACACATTCACACACACGCACACACACACACACATACACACACACCA
CACACATACACACCACACACACACATTCACACACACGCACACACACACACACACACACACACACACCACACACATACACACCACACACACACACACACACACACACACATTCACACACAC
GCACACACACACACACGCACACACACACACACACACCACACACACACACACACACACACACACCACACACACACTCACACACCACACACACACACAGACACTTCACACACACATAAATGT
CATAAAAATTAAATTAAAACCAGAGTAGAAAACTCTGGTAGTGGGTGAGGTGTCAGAGACAAACCCTCACGTGAGACAGCCATATCTCTGTCCCAGCACATGGGAGGCAGAGGCATTTCC
AGGCTAGCCTGGTGCAGAGTGAGACTCAACTTCAAAACAAACAACAATGATGTATAGTCAGATTTTTAAAAAAATACTCTCACTGTGACCACAAACTGGGAGGGATTTAGTTGTTTAAAG
TTTTTTTTTTTTTTTAACTCTAAGGATAAAAGCCTTTTATAATATCATTCCGGCATTCAATCTTTCACAGTCTGACTTGCTTCTCAGGCTCCACATCTTCCATACACTATATGGAGGACT
GGCTATTGTTTCTTGTGTCTTGTTTTGTTTTAATTTCATAGAATAGGAATTGGGATGTGTGGAAAGCTTCCTGTAAATGAGTTAACTGAGCAGTGCCTGGGGTGTAACAAGCACTCTCTA
GGAATGAGTTCTTTGTTGTTATTGGCCCAGGGGCTAATGTCTGGGAGCTGCCTCTTGCCCAGGACTTGTTGCTGAGTACCTCTCAAACACCCTCTGTTCCAGGTGCTGGAGGCCACAGCT
GCCCTGTACAATCAGGACCTGTCTCGGCTGGAGCTACTCCCAGGGGGGCTTCTGGAGAGCCATGGAGACCCTGGACCCCTTTTCAGCACTATTGTCCTTGACCAGTTTGTCAGGCTACGA
GATGGTGACCGTTACTGGTTTGAAAACACCAGGAACGG
GGGTAAGGCTTGCCTGGGCTGTGTCTTAGAATCTACTGTGACCTGGACCACAGGCCCTCTGCTTGGCCCTCCCTGCCCTCAC
AGGCCTCAATCCTAGCCCCTCTGGGTCTCTCGAGTGAGGATTAGTCTCTGATGGCTCTCCAGGCTGGCAGGCTCTTACAAACAGCTATGGACCAGAGTCTCTGTCCCCATGGGATACCTG
AGTGTGAGGCCCCAAATCTCTCCGTAACCCTGACAGTTCCTTCACCTCTCCTATGTCCAGATTGTTCTCTAAGGAAGAGATCGCAGAGATCCGAAACACTTCCCTACGGGACATTCTAGT
GGCTGTCACCAATGTGGACCCCAGTGCCCTACAGCCCAATGTCTTCTTTTGGCTTGCAG
AGGTATGTTACCTAGAGGTAGCTGGCGGGGCGTGGGTCCAGAGTCTTGTCCTTTCTTAACT
GTAGGCTTGGTTTGATGTGGCTGGATGACCCCTCTAAGTTCTGCCCATGAGAAATTTGATTCTAGGTGCCAGGGTTGCCACATACAGTTTCCCTTTGCACAAGTGTACTAGATGCTGAAT
TAGGGGCAGGGCCAACTCTCTTAAAGACCTGGGGGAGACTCTTACATTCAGATGGAACGGGATAGGACTGTGAGTGGCATCCAGAGGGCCAAATGAGGGTAAAGAATATAATATTTCACA
GCAGTGCTAACAAAAAGATATAGGGGCAGGGCGGGGTTAGAGATATTGAGGTTCATGCTGGGACCTGCTTGCTATCCACATAGGCAAATGCCATCATCTTGCTGCAATGACAGGGGTAAA
CAGCCCCATCCTCTCTAGTTCCCAGAGCACCCTCACCTCCTCTGTTAATACCCTCTTCAGTGACCTTGTGACAGATTGTGGCATAATAGTACTGGATACTCCGATTTCCTCTGCCTCCCC
AGGAGACCCCTGTCCACAGCCAAGTCAGCTCAGCGCCAAGGGCCTGCCAGCCTGTGCCCCCCTCTTCATTCGGGACTATTTCGAGGGGAGTGGATTTGGCTTCGGACTCACCATTGGGAC
CCTTTGCTGTTTCCCCTTAG
AGGTAGGAGAGTAATGGGTAGGCAAGGTGGTGCTATTGAAAGGTGTAGTCTAGTGGGTGTTTTTATGCATAACAACAAAACAATGTAGAGTACTGTCTCT
CTGGTGAGAAAAGCATTAGGGAAGGCAAAGGTGTCTGGCTATAGATAAGTGAACTCCAGGGAGATTTGCTTCCCTGATCTTTTGGGATGCCCCCGGCCTAGCTTGGTCAAGAGTCCATAA
GAGTCCCTGGTCTACTGCTGTCTGTGAGAGCCTGCTAGCCTAGGGACCTATCAGAGACAATTCCTCAGCTGAGAAGCAGCTGGGACAGACTCAGTTTCTGGAACAGGAGCATGGGAAGGT
TGTGTGAGGGTGGCCCAGCAGCCTGGTGTGGTGCATCTAGCTTGTGGTTTGAGGAATCTGGATTTAGTTTCTGGCCGGGAAGGGACTTGAGTAATGGAAGCAATGGTGGCTGATATTTTA
GACACTACCCAGAGCTTTCCATGGGTGGCAACGTGCTCCCTCCACAGAGCCTCGATATTTGAAAGTTGGGCAGCTGGAGGGTCAGAAGTTAGGAATAGAAGGAGCTCTTCTGAAGGAAAT
GAGGGAGTGACTTTTCTCTCCGATGACCACTTTTCCCTGAACATCCCTCTCCACTCTCACACCAGTCAGCCTCCTTAGTGCCTGGATTGTTGCCCGGCTTCGAAAGAGGAATTTCAAGAG
GCTCCAGAGACAAGACCGCCAGAGCATCATGTCGGAGAAGCTTGTAGGGGGAGTGGAAG
AGGTAGGCCATGGGGTAGCCAGGGCGGTGCTGGGAAGGTCATGACTTGGGGCTATGATCCA
TACCCCACCCCCAAGTCCAAGGCAAAAGATCCTCATTTCCAGGGATGTAGGAAAAGCCTGAGCAGGTTGGGGAAAGCCATGGTAGACACTGGATCTGCAGTTTTCCAAGCTTCAAGGCTC
CTCCCAATGATCCTAAATAAATGGAATGTGAGTGAGGAGTAGAAGAGTCATAAGACCCTGCCTCCATCTCAAAGGAATGTGACTCACACGTCCCGAATGGCTTTGCAGCATCCTGTGCTG
GAACTGTGCAGGCAACAGGAGTCATTAATGAAGGTCTGAAGTCAAGTAGGATTGGTATCTTGGCTCCAGTGCTGAAGACTAGCTGTTGGACCTTAGGCAGATTTTGTTTTAAATCTCTCT
AGACCTGTTTCTTCTTATCTGTAAAGTAGCTATCCTAATGGTGCCTGTGTCTTAAGTTGTGAAGAAATGTAACAACCAATTCAAAGCACTAAGGCTAGCATCCGGCAAACACTCAGGAAA
TAGTGGCCCTTATTTGCCTCGTGGGTTAGAGGAGCAACAGCACTGTTCAGGAGAGAATGACCCTAAGAGTCTGGGGTTGGTGGGGTCAAGTTGTTGCTGAGACCCTGCCCTGACCCTCTC
TCTCCCTATGGGTTCTTCTGCACCCAAGCTGACCCAGCCCCATCTCTTGCTTCCCAGCTTTGGAGTGGCAGGGCCGCAATGAACCCTGCAGGCCAGTGCTTGTGCACTTACAGCCGGGAC
AGATTCGAGTAGTGGATGGCAGGCTCACCGTGCTCCGGACCATCCAGCTGCGACCCCCACAGCAGGTCAACCTCATCCTGTCCAGCAACCGTGGACGCCGCACCCTGCTGCTCAAGATCC
CCAAGGAGTATGACCTG
TGGTATGGCCCAGCTGGCCTCATCTCAGATGAGGCAGTTAAGTAAAGGGAAAGGAGCAGTAAGCCAGGAGACAGGGGTTTTGGCTTCCAGTTCCCAGATGTGG
TACCTGATAGAGAGATGAATTTGAACATGTCCGCCCTGTTCTAGATCTGCTGGCTGACACCGTCTCCTCTCACTCTGGTGGCAGCTGGCAGCCTTCTTCTTTGGTTATAAGTCCTAGCCA
TGAGTTCCTGGAAGAACCTGGGTCCTCTTCCCTATTCTCTTATTTCAGACTCTAGAGGACTTCCTTTTTCTTTTTTCCCCACTAATTAATTAATTAATTAATTAATTAATTAATTAATTA
ATTAATTAATTAATTAACTTTACATACCCAATCACGACTTGGAGGGGAGTTAAACAGGAGGCTGATCATGTGTTTTGACTACCCAGATCACAGTCCACTCCACCCTCTGCCCCAATTCCT
TCCCCAACTCCAACCCCTAGTCCCAGCTATTCTCCAGTATGAAATATGTGTCACTAAAGTACACTTTTCTCTTCTGTAAATGAAGGACAGTTATCTCTTTTGCAAGGCCACACCAATGAC
CCTTTGTGTGTTCCATGTGAAGCACCTGTCCCTGAGAGGCTCTGACACGTTTACCTCTGCTATCTTTGAAGGTTCTGTTGTTTAACATGGAGGAGGAACGGCAGGCACTGGTGGAAAACG
TCAGGGGAGCTCTGAAGGAAAATGGGCTGAGCTTCCAGGAGTGGGAACTGAGGGAGCAGGAGCTGATGAGGGCAGCAGTGACCAGGCAACAACGGGGCCACCTCCTGGAGACCTTCTTCA
GGCACCTTTTCTCCCAG
AGGTGTGTACATGGGATCAGATCTGGTGTGTGCATTTGCATGTGTGGGTGTGCATACGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCGCGTGT
GCATCTGTGGTGACATCCTTTCCTATATGAAGCCATGGGGATGATCCTTCAAATCTCAAGGCTTGAATGCTCAGCTGAAAAGTCTGTCCTGATTTAGATCAAGTCACCAGGAGTTACTGG
AGTCCTAGGCCAGAGGCCAGATCTGAAGGTATGGGGGTAGGAGTATGTCCCAACAGATTAGGTTCAGCCACTTGCCTCACAAATCAAAGTGGTTACTCAGGGAAGAAATCCAATCAACAT
AGCCATGTTGGGAAGACAGATGGAATATCTAAACACTGTCTTTGCTGATACTGACACGTACTTCTGGATTATATAGGGAAAGGGCAGAAGAGAAGGCCTAGAGGCATAGTTAGTCAACCT
TAGCCAAACCATGGTCTGGTTGGTTAGTATTTCAGTGTCAGATCCGCAAGTTGGCTCCAGTGACTGTGTTACTTCCCGTTACTTGGGGAAACATTCTGGTTCCCATAAGGTGAATTGTTT
TGCTTAGGTGGGCAGCTTCGGTTCCTATCATGGAGGTACTGCTTCTGTTTAAAGAGTAATGTCATCACGGGGGTGATCTGCCTGCAGGTTCTGCTTGCTGGTCCAAGGTGACTGCAGGTT
CATGGCAGCAACTAGAGATTTTCAGGGGTCTGGAGCAGGATGTAAAGTCTGGTGGTAAAATACTTTTGTTACTCTGTTCTTGAAGCCTTCATCCTTGAAAAGGGATGAGATAGGGCTGGC
GAGACGGCTCAGTGGGTAAGAGCACCCAACTGCTCTTCCAAAGGTCCAGAGTTCAAATCCCAGCAACCACATGGTGGCTCACAACCATCCGTAACAAGATCTGACGCCCTCTTCTGGAGT
GTCTGAAGACAGCTACAGTGTACTTACATATAATAATAAATAAATCTTAAAAAAAAAAAAGGGATGAGGTAGATTAGGTAAATTTAGGACTGATTACCCGATGACATCAGGGAATTTTTG
TTTTGCTTTTTCAAAGGGATTTATTTTTAATTATGTCCACATTGGCAAGGGACAAAAGAATGTGGGTGGCAGCAGAGGGCAGAGGTTATCACATCCCTCTGGGACTTGAGTGACAGGCAA
GAGGTTGTGAACTTCCTGGGAAACCTAATGAGGGTGTTGGGAGCTGAACTTGGATCCCCTTGAAGAGAAGTGTGTGCTCTTAACCCCTAGTCTCTTCAGCCCCTAAGCAAGTAACATGCC
TTTGTGCCTGAACTGAGCAGGGAATGAAAGCCCAGAAGAGATACACAAAATAAAGGCACAGAAGCTGAGATTTACTCTGCTCTGAGGAGTCCGTAGGCCCACTTGAGGAGCTAGTGCTCT
TCGGCAAAAGCGGTCTCTAAATTCTTCTCATATTTACTTCGAAGATTTCCCAACCCATGTGAACCCTGTCTCCTGATGTAAGACTCCAGGGAGACAGTGTGCAGGAAGGAAGCAGGGCAA
GCCAGTACCGCGGGGCTCCTGAAAATCATACTTCATCCTTTCTTCGGGGAGTGCACCATGGAGATGTAATGTCTGCCATATGCATTTCTGAGAACTACCAGGAAGATGTGGAAAATTTTG
ATAGAGGGGGAAATCCCAAGACTGATGTCCACATCTAGTACAAAAATAAAGGTAGCCTGGATAGAACGCTACATTGGAGACAGAAGATTAAATAAGAGCCTGGTGGCACACACCTATAGT
TCTACACTGAAAAGGAGAAACACAAGGATTTGGAGTTCGAGTCCAGCCTGGGCTACTGTCTCAAAACCAACGATGTGCCGACATAGTTTAGTGGTAAAGTACTTGCTGGGATGTGTAAGA
CTCAGGGTTCTATCCCCAGCATGAGGCTCATGGGTAGACATGAATCCAGCATGCATGCCATACCCAACACATTAATTAATCTGTTGGGATGGTGGTGATAGTCACACAAAGACTGGTATG
GGATGAAGATTATAAAAGCAATGCAGAAACATGTGATCTAAGATGTTAGAGAAGAAAAGCTTTCAGTCTGGTGCAAGTTCATGATGGAGGCAAGATTGGCAAGGGCTCAAAGGTGGAAGA
GTTTTGGCCCAGGAGAAAGGGGTGAGTAGGATTGAGCACTGAAGAAGAGAGAGAAAGAATGAGTGTCTGAGAAGGAGCAAGGCAATTAGCTGGGAGAGGATTCATACAGGAGACTGTTAT
CTAATGGGCGTGCGCAATGGACTCTGGGTCAGACTTAACTCTTCACCTAATTGAATATGGAGTTTGCCTAAGAAACAAGGGACCCTTGGCTGGTGAGGAGGTCTCCTTGCTTGGGCACAA
GTAGAATCTTGGCAACTGCACTCAGGCCAGTTTCCATCAGGATGAAGGAAAGACCTTGTTCCGGAAGTTTAATAGACTGTCCGCCATCCCCATGGCTGCCCTGTACTTTCCATTTTGAAA
TCCTTCCCTCTGCAGCCTCTCTTGCTGATTTCCATCATAACCTCTGATAAGTGAGGCCGGTGAGGAAATGAACCCCAGACAAACAAAGGATGTGCCCGAGGTTATGGTGCACACAGGTGG
CAATGTTGGGACATGAACTCAGGTCTCTTACCTCCCGCCCCAGGCTCTTCCCACTAAGCACCTTGTCTGAAGTGCAATGCTTGTTTCATGAAAAGACAGTCAGACTTGAACTGAGCAGCT
GTTGAGAGGCAGGAAAAACAGGTATTGTGACCTGAGGCCTACCTCTTTCCCTGTGTCTGTTCTCTTGCTAGAGCAGTCCCTGGGTAAGATGGGGGTGGCCCATAATAAGAATTTTCCTCT
CCAAACCCTTGAGATATAAATCAGTCATAAAGGATACACATAGTCTCAGGAACCCCAAAGTGGGGTCTTTGGCTTGTCTTGGAAATATCTGGAAGAGAAAGCGGTCAGCAAACAAGGTCT
CTCTTCGATTATCTCTACTTTCCCCTTGACCCTTTCCTCTGCGAGTCTGAACCCACTGTCAAAGCATATCTGGGACCTCTTGGTTCTAATTCTAAATACTCAGGTTAGGTCAAATATACA
TACTTGGTTCAGTCAGCTAAGCCAGAGGGCCAGGACTTTGCAGTTTAAATATAATTACTCACAGACTGCTTATGGTGGTGTGCTGGGCAAATATCTGCCTCAGAAAGTAGCCGCATCAAC
CTGTAAGTGAAAGATGCCTCCTCTTTCCCCTACCCCCCACCTCTGGGGCTACCTAAATGCAGGTGTTAGACATCAATCAGGCTGATGCAGGGACTCTGCCTCTGGATTCCTCGACCAAAG
TGCGTGAGGCCCTGACCTGTGAGCTGAGCAGAGCTGAGTTTGCAGACTCCCTAGGCCTCAAGCCCCAGGACATGTTTGTGGAGTCCATGTTTTCTCTAGCCGACAAGGATGGCAATGGCT
ACCTGTCCTTCCGGGAGTTCCTGGACATCCTGGTGGTCTTCATGAAAG
AGGTGAGGAAGGAGAAAATAATTGTCCAGACAGAAGTGGGCTACTGATGTTGTATTGGAGATAGAGAGCCTG
AGGCTAAGTCTTCAACTACGACCGAGGCCTGGCAGTCTAGAAAGGGTTTCTAGAGGTTGGGTGGGTCTCTCCTCACAGAACCCTCCTTCTTCCAGGCTCCCCAGAGGAGAAGTCTCGTCT
TATGTTCCGAATGTATGACTTTGATGGGAACGGTCTCATTTCCAAGGATGAGTTCATTAGGATGCTAAG
AGGTTGGTTGTTCCAGCAGGCAGGACAGGGACTGCCAGGGAGAGGGCCATC
AATGGGATAGCAGAGGTATAAAGGAGAAGCAGGGGGCATCCTCTTTATCTTTGTATCCAGAGCCTTCTAGAATTAATAGGGAGCTTGGGCTTCAGCTAGTTGGGACCCAGTTATGGAGGA
TCCTGACGTGGATGGCCAGTGCTTGCTTCCAACCCTAGGTCCTTCATCGAGATCTCCAACAACTGCCTGTCCAAGGCCCAGCTGGCTGAGGTGGTTGAGTCTATGTTCCGGGAGTCTGGC
TTCCAGGACAAGGAGGAGCTGACCTGGGAGGACTTCCACTTCATGCTGCGGGACCACGACAGTGATCTCCGATTCACACAGCTCTGTGTCAAAG
AGGTGGGGCTGCCTGGTTAGCAGGGC
TGATTTATTTGTTGGGTATTATCCCTATATACTTTTAGGAACCCACAGAAACACTTCAGAAACACAAGAAGAAAAATCAATACAATAATGAGTACATAATATAGCTAATGCAGATTATAT
TCTCTTTTATACCCATGCAATTATCAAATAACATTGCTAATTTATTTTTACCTGTATGGAGAAAGGAGCCCAAGAAGATGAAAATGCCTTGGGCTTATGAATGTATCCTGGCTGCTGAAG
TGGGTGGGAAGAAGACTTTTGTTTGTTTGTTTGTTTGTTTGTTTGTTTGTTTGTTTGTGACAGAGTCTTGCAATGTGCATGGTGGGTAGTCTGGAACTTGCAATGTAGGCTAGGCTGGCC
TTGAACTTGTGGCTGTCCTCCTGTCTCTGCCTCTAAATGCTGAAGATAACTGATGTGCGCTACTACACCAAGTCTTCAGTAGATGTTGACTGGAACCGCCCTGTTCCTCCTGGCTCCTGG
CCAAAGCCACCCCACCCTTGCATCTCTAAGCTTGCAGCAGGGCAGAAACAATGTTTCTTTGTTACAACTGGATTTGGCCTGACTCAGTTCTCCTCAGCTGGGTCGTGTGGTTCTGGTTTA
TTTGGGGTTTGGTCCCCCAACTCCCACAGTATCTCCTGGTTAAATGCTTAGTAAGTGTTTGCTGAATACATCACAGCCCAACTCCTTTGTCCTTCCTGCTCCTTCTTACCCTGGGTCTGA
CTGGAGGTGGGTGGAGGTCAGGGTCTCAGTGATGAAAGGGACAGATATCAAGCAGGGGGGTCTGTGTGTGGCCTGTTCTGAGCTGTCACGACATCTTCGTGATTCTTCTCGGGGCGTGTT
GAGACAGAACCTAGTCCTTCCCATATTATGAGACAAGTGGGGGCTGGCAGCTTTGCTGAGAGACGGGAGCAAGATGAGCATGATGTGGATAAACTTCTGCACGAGGCTTCCTCTGGCCTG
AGGGCGAGGGGAGATGTTGAAGAAGAAAGTTGAGTTTGTAGCTTTTCCTACCAAGCCAAGGCAATGGTGGGCAGAGGCCAGGGAGGAACCTGGAAGTTTCTGCCCTGGGATAACCAGGCA
GGGGCTTGAGGATCAAGCCAAAGGTTAACTATGTCTTGATTCACTTTTAATCACTTGTTTTCTTCTGATCTTATTTGAGAAAGATTCCACATGACAGAAAAGGCACAAAAATATTACGAA
CAGCCACTCCCTTTTCATCAGAATCCACTCTTCATCGCTATTTCAACACATTTGCTGTTTACTGAAAATTGGAGAGTGGATATCTGAACTTGGTTCTAAACACTTGATGTTAGAGTGAGA
GGTACAGATCAGTCGTTAAGAGCTCTTGTAGAGGACCCAGGTTCAGTTCCCAGTAACCACATGGCAGCTCACAACCATCTGTCACCAAGTTCCAGGGCCTCAGATGTTCTCGTCTGGCCT
CCTCTGGCATCAGACATACATATGCTACACATAAATACATTGATACAAGCACCCACATACATAAATTTAAAATAAGTAAATCTTTAAGTGCTTGAACTCCACGTAGATCAGTCTATCATA
AGCCAAGCCATCTTTGGTGTTGGCTCAGAACTTAAAAGCCCCTTGGAGGCCCCAGACCTCCTAAGAATTTGCATTTGCAGTTCGACCTTGCTTTGTACAGCTCTGACAGAACAATGAGAT
GAAGCCTCCAGGGTTTTATTATGAACATTTTCAAACAAAGAATAGAAAGACTTTTCAGTGACCTCCCTTATCGCTATCTATCACTGATAGGTAAGTGCAGTTCCTATGGGGGCCAAGAGC
TGAGGCTGGGATCTCTTTTTAGTGGAGCCTTTCTACAGGCTTGGGCATAGGAAAAGGGGGACCCTGTGCAGCGAGCCAGGCTCTCCTAGACTCTGGGCACTGAGCTGTCCCCTAACCAAG
CTCTGCAACCCAGGTGTGGAAGTGCCGGAAGTGATCAAGAACCTCTGCCGGCGAGCCTCCTACATCAGCCAGGAGAAGATCTGTGGTAAGCTCCCGTCTGCATGTATTGGGTAGTTGTCA
TTTTGCCAAGAATGGCTGAGGTTGCCCCACCCCCAGCCCCCACTACCTATTGTAGCACCTTCATGCAAATAGAAAAGGGCCCCACTTCCTCCAAGTGGACAGACACATCCTTCATCAGGA
TGAGGAGAAAGCCTGCTGAGTGTCAGCAAAGCTTGCTTCCTGCTTGGGCCAAATGTCCTTGTAGAGGACACAGTTATCTATGGAGGCCTCAACAGGGACTCATTCTCTCTGTGTCTGCCT
ATTTGTGGGAATCTTGCTGTCCCATGTGGAGGGTTTTGATCTTTCCCGGACAAAGTTGGTTTGGAGGCAGAGCAGGAGTCAGATGGTACCTTTTGCCTTTCCTTCCTAGCCCTTCGCCCA
GAATGAGCGCCCACTGTGCCCGAAACAACATGAAGACTGCGTCATCACCACAGAGACTGCAGTGCCCCATGGACACAGACCCTCCTCAAGAGATTCGACGGAGGTTTGGCAAAAA
AAGTA
TGCCTGTTGTGCCCCTAAAGTCTATGCATCCCTCCAACAATCCATTGAGTGGTTCAGGGCTCTCTGCTTTACTGGCAGATAAATACTCTCTGCCCCAGAATGCTTATGTACAGTGAGTCT
GGTGCACTGTACTGATGAGTACTGGAATGATAGGAAGGGCAAGGGAAACTCAAGGCTGTTTTCTCCCTCTGCCTGGGAAGTCGGGAGGGTCTTCAATAGATGCTCTGCCCTAACTAGGTT
TTTATTGCTAGGATAAAATCATGACTACAAGTAACTTGGGGAGAAAGGAGCTTATTTGGCTTACAGGTTACAATATATCAGAGAGAGGTGCCAAGGCCGGAGCTTGAAGCAGAAACCACA
AAGGAACACTGGTTACTGGCTCGCTTCCTCCAGCTTGGTCAGCTACCTTTCTTACACAGCCTAGGCAACCTGCCTAGGCATGGCACTACCCATGGTGGGCTGGGTCTGCTGACATCAATT
AAGGAAAAAAAATATCCCACAAGTATGCCAATCAGATACCAGACGTGTCAAGCTGACTACTAAAGCTAACCGTGACAGGCCTCTTGAGCCTTCTAAAGCCTCACTGTGGGTGCCTAGTAG
GAACTACAAACAGGGAGAGGAAGAGACTGTCTGTGAATGAATCCTGGTGTAGATGGAGTGTATCCCCAGAGTTGAAATAACTACTTGGAAGTCAGCCCTCACTTAGACAGTGGGGGGCAA
AGCCTTCAGGTCTGAAGCCTGCTGCAAGAGGCTCTGTCCTTCCCAGGCTGTCCCTGAGGTAGCAGGGTCCCATTGTATTGAGTTTGACAAGCCAAAGGCTCCCTCTCTCCTAGGGTAACT
TCATTCCAGCCCTTACTGTTCACTGAGGCACACCGAGAGAAGTTTCAACGCAGCCGCCGCCACCAAACGGTGCAGCAGTTCAAGCGCTTTATTGAGAATTACAGGCGCCACATTGGCTGT
GTGGCGGTGTTTTACACCATCACTGGGGCGCTCTTCCTGGAGAGAGCCTACT
CTGTGAGTGACATCACATACCGCAAGTCTGGGACAGGGAGTTGGGATCTATTGTGAGTGACACACATC
CCGATGTAGGGTTGGGGTTGGGGGGTGGGGGGGGGCGAGCTGCAGTAAAGGACAACAGCGTCGCCTACAGCCGCACTGTTTCCTCTCCACAGACTATGCATTTGCAGCACACCACAGCGG
CATCACCGATACCACCCGTGTAGGCATCATCCTGTCCCGGGGCACGGCGGCCAGCATCTCCTTTATGTTTTCCTACATCCTGCTCACCATGTGTCGCAACCTCATCACCTTCTTGCGGGA
GACCTTCCTCAACCGCTACATTCCCTTCGATGCTGCCGTGGACTTCCATCGCCTCATCGCCTCCACGGCCATCATCCTCACAG
AGGCAGGGGCTGCTGCTCTGGGCTTCTCTTGGTGCCT
TTTGCCCTTGGTGGCTTCCTCTCCTCTCAGACTCCTCCCCACTGTCCTTTGCACCTAACTTTAATGTCGATAAGGATGGAGTTAGTTGGGCTGTGGGATGAAATGAAGCCCAGGAGCCTA
CCTTTCTCTGAATGGCTTTTCCTGCATTTTCAAGGGCATCCCTGCCCCAACTTCTGACAGTCTACCAAGACTCTAGCACAAGGATACAAATGATTGCTTTCCTAGTTCGTATGCTTTAAA
ACAGATCTGTGAAAGAAACCAAAGGAATGTGCTTCCAGTGGTATAATTTCAGACTTGTGGCTGTGTTCGTGGGTGGAACGGGGAAGGAGTGGGAGGTTGGTTACAGGTCAGCAGCCCAGC
CCCCAAAGGTGCTGTTTCAGTCTGCCCTGTTTGGCACTTGACTGTGTTGTGCACCCTTGCTGGGCTGTCTCTGGGCTCACCACCTTGTCTGGTCTTTCTTAGTCTTACACAGTGCTGGCC
ACGTAGTGAATGTGTACCTGTTCTCCATCAGTCCACTCAGTGTCCTCTCTTGCCTCTTCCCTGGCCTCTTCCACGATGATGG
GGGTAAGTGTGTGTCAGGAGTGAATTTCTTGAAGGGAG
AAGAGAAATTTACGTGGCCTAGAGGACAGTGTCACTTTCTGGGATAAAGTGACAATGATCAAGCTGAGCCATTGGCAGGAGAGACTGGTGACTAGGTTGTGCTGCTCCTCTGGAAACCCT
AGGAGAGACGCCAGAGACCTCAGCTCACGACTTTGCTGTGTCTTCTGCACAGGTCGGAGTTCCCTCAGAAGTATTACTGGTGGTTCTTCCAGACTGTGCCAGAGGTGAGAGACCTTCCCT
TCTATCAACGTCTAGGCTTCACTCCAAACGCCAGGCTCTGGGTTCTGTCACTGAACAGCTAAACTTCCTCAACTCTTACAGTGAGCCAGGCTCTGTCCTCGAGGACAGAGGCAGGAAGAC
TTAGCTTGACTGCATTATAACTCCCTCATCCTTGAGCTAGTTCCTCCCTGGAAAAGTCTTACTGGCCCTCAGTCTGGTTCAGTTCTCAGGCGGTTGGGGAGTAGGTCCCTTTTCATAATA
CATAGACCTGTCGTGATGTTTGCCTTGAGAAATGCTGTGTCCCGGCTGCATGGGAGAAGGACTTGGCTTTTTATCAAACCAGACATAAGTCCCTACCCACACTGTAAGATTTCTTGACAA
AGGTCATGGTGGGGGTGGGTGGGTGGAGAAAGCATATTTCTAGCTTCCTACAATCACCCATTTCAGAGCTAATAGCTGCGAATCGATTAAGATTTGTCCTAAACCTATTTATATTTAAGT
CTGTGTCCTCTTGGGGGTCATGTGTTTTTATGCACTCCTTTCTGTGAAATGCAGCAGGTTTTTTTTTTTTTTTTTTTGGTAATCCTACTGCTTTGAACTTCAGAGTGCGCTCGCTGACTT
CGACGCACTGGGATTTGGTGGATAAGACTGTATTTATGCTCCTCTCTCTACTCACAAGTTTACAGGCTGTGGTTCAATCCCCTCTTAACCTTCGCTTCTCCACACATCAGGGCTCTAATC
TTCCTAATTACTGTCTCTCTCCTCCTTGATCACTGGAGGCTATCCTGGGTTTCTACACCCCCATCCTGGCTCTAGTATTACCCTCTCTGTACCCTTGACATGGGATCCTCCATGAAAGAG
GATGGAGCTTTCTACCAACTCCAGGCTGGACAAAGAACTCTGGCAATCTGCTAGGTTAGTATGGTCCCATGCACAGATTGGTTCATAGTTCATGTCAAGTCCTATGATAATCAGTGGTTG
GTGTAGTTTTGACACCATGGGGACAGAGCATGATATTCCCCATGTCTCATTTAGAGGCTTCTGTGCATTCAATTCATCCAGCACACATTTATACAAAGCCTGCAGTGTGCCAGGCCTGGC
AACAGGCAGGAGGATCAGTGGTGAGACAGCCTAGTGTGGTCCTTTTTCTTGAGGACCTGAGGGTCATGAAAAGGGGTGACACTTAAAAAATGTGATGACACAGGTGGAAAGGATTACAGC
TATAGACGATGAAGTGGCTCTGTTGAATCAAACGGTACCTATGATCTGGGCATACTTAAGTTCAAGACCACTTTGTCACTCCTCCAGTTCAGACAGGAGTAGAGAGGGACATGGCTGAAT
ACCCCAGGACACACCCTCCACACTGCACTGTCCCTCAGTCTTCTGCCTCCTGTCCTCTTCACAGGTCTCACTGGGGTCCTCCTGCTCCTGGCCCTGGCCATCATGTACGTCTTCGCCTCC
CACCACTTCCGCCGCCGCAGTTTCCGGGGCTTCTGGCTGACCCATCACCTCTACATTTTTCTCTACATTCTG
TGGTGAGGGGTTCTGGCCGTGGTCCAGGCCTGTGGGGTATATGAAAGA
CATTCCTTGGGAGGCCATGGAAGCTGGGACATTGGTTTTCCATCCCCTAAGTTATTTCAAGTATCCATTTCTCCACGTCCCTCTACAAAGATGGAAATTATAGAGTGGTGCTCTCCAGTA
GGTTGACCCCATTATGCGGCTCTTGGAAGATTCCTTCCTTTCCATGGGCTTTTTTTTTTTTCTCAGTAGTAGCTCTGCCAGGCTCATCCACATTCCTCACAGACTTCCCCACACCATTTC
TTTCCAGTTCTTCTCTACCTTTGAGTGGCTGGTTTTTGGTTCCATAGTGGACTTCTTGCACCTTAAGGAAGAATTATTCTTTTGGAGGAAGTTTAAAGGGTTCTTTTCTGTTCTGATCTC
TTCTGAGACTGCATTAGCCGCATCATCTGGCCAAACAACACCTGTAAAGTTAATAAGGTCACTCAAACCACCAGCCAGCCAGATTGCTGATAAGATATACTTTAAGACTCCACCTTGTTA
GGTTTCAGATGGAACAAATGGTTCAAGAGGACGCCGAGATGGATTACTGGAGGATAAGGAGCTTATAAGTGTTATCAACACCATGGACAGGCAGACAGACAGAGGTGTAGATGGTCTGGG
ATCCAAGGAGAGAGTTCAGGTCCAGATACCAGAGACAGAATGGCTTGGGTCTTTGAAGACAGTCAGAAGCTAGGTGGCAGAGGAAGGGATCTCTTAGACCTTTTGAGGATGAAGGAGGTT
TACACCAAGAACCTGCAGCCAGGAGGAGGCAGAGAGGGGAGCAGAGAACAGATGTGGCATTCCTTTGATGTAGACTCACTTCCCCAGGAGATGCCATGACACTGGCCTGTCAGCTAACTC
AGGACTCAGAGACAATGCCTGACAGTATCAGTGAGAGCCGGTCCAAGCAGAGGCTGGGTTCTACTGTTGCTGTTCTTACACTGTCTCCTTCTCAACCCAGGGTCTTTTTTCCTCATGTTC
CCTCCCTTCTTCTGATCCTTTCACTGTCTTGTCATCAGCTGATTCACCTCAACTCCCGAGCCAACTCTGACCTGGCTCCCTGTGCTATTACACAGATTGCCCACCTTCCTCAGGTACACA
GTACTCCGCAGAGGGCACTGTACTCAGGTCTGAAGGCCTTCACTTTTTCTACCTGATGACTGATGGCTTGGCTGCTAGCATTCATAGAGCCTAAGCCCCCTTGACTGGCATTTTTATTTC
CTAATAGAGCAGCATACAGGGATCTCCTTTGTTCTGAGATGAAGAATAAGAATGTACCACTGCCTGGGTGTGGCTTGATCCTGTTACCCCACCCCTCCTCCTCCCAGATGCAGCTCTGTC
TTCACTAATAGCTGGGACACAGACACACAGACACACAGACACACACACACACAATTTGCCTGTGGCTCAGCACATCCTGATTCTGAAATAACTATCTGGCTTGGCTTAGGATATTTCCTA
GAACTGCTGATGTCTATTTCCAAAGAACCTCTCCCTCCTCTGGGAGCTGTGGCTAACTAATTTCCTCCCTTCCCACTAATTTCCTACCTATTCAAAAATGTGTGGATCCCTAGCCTTCTG
CCCTTTGCTTCTGCTACGAAAATGCTGTTTCTTGTTTCCTGGTGATAAAACTAGAGGGAAGATCCTGTAGAGTGGCTAGCTTGATACCCTAAGTCCAAGACTACTTCCTGATTCATTGCT
ATTGTAGACAACACTGGATTGTTGGGCAGCTCTAGCCTGGCAGATTGGGAACCTTTTATATGTGGGGAGGGAGATCGGGAACATAGCAACTATCTTATCACTTATCACAGGGGGTGGAGG
AAGGCACTTGGCTCTGGGCAGAAAGGAAAGTTATAAGTAAAAGACCCCAGCATAGAGCAGACCTTGAGAAAGAATGTCTAAGCTGGCAACTCAGAAACTGAACTGCCCCACCATGAAGGA
GAGCTTTAAAAATTTGGAACTCTTTACTGGGGAAGGAATTCCTGAACAAGAGGCCTGATTTCAATGAAACAGATAGCAACCAAAGGTCTCTTCTGTCTTAGCTCTGAGGGAGGCCCAACA
GGTGGCAACACTAAACCCCACCTTTAGGAATTTAGGATTTGCTACAGAGATCAGTGCCACATGCACACCAAATAGAAGGAATTGCTGAGCAGAATGTCCCAACAGTAAGGCCTAGAAAGT
CAAGGAGGAAAGTTTTACTTACACTGAACTAGTCAGGGGCGACTTTGAGAGAAAATGGGACTCAGGCCACAGCTTTAGAAGAGAGAGCGAAACAGTGACAAGGCTGAGTGGGAACTGAAG
AGCAATCCAGGTAGAAGGGCATGCACACCGATATAGGGTGGGAAACGTGACAGACTATCCAGGGACAAAGGAGACAGGCCTGGGTAGCTGGCGACATGTGGAGGTGGCATATAAGGCAGA
ATGGTTATGGCTCATTAGAGCCCATGGGCATGGTGGAGCACAGAAAGACAAGAGCAATGGGTAAGGAAACTAAGCTTGGGCCACACCCATGACTGGGGATGACAGTGGAATGGTGGCTGG
GAAGGCTGAGGCAGAACCAGAAGAGCACTGTTGCTGAAATAGCTATGAGACACGGAGGTGAGGATGGGTCACTAGTGTCACAGGCTACAGAGAGGAAGCAGGCATGACCTTAAAGAAAAC
CTTGCAGTAGGGGGCTGATAGCACATGCCTACAGTCCCAGCTACTTGGGAGCCTGAAGTAGTACTGTAAGTTCACAGCCTGCCCGGTCTACAGAGTGAGTTCAAGGTTAGCCTAATTGAA
TCATTAAGGCTTCCTCAAAACAAAAAAGTAAGAAAAGAGCTTGGATGTAGCTCTGTGGTGAACACTAATCTAGCAAGTGTTTTGTTCTCTAGGCTTAAATCCTAGAGAACAAAAGAGAGG
AAGGGAGAGAATCTTGTGTAGAGGTGGTTATAGTCTGTCAGGCTCTTTCATCGAAAAGGTAGACTAGTTAGGTGTTCTTAGCCACCAAAAGGTGGGATAAACAGGACGTCCTCTTCCTGG
CCATTACTGAGTACTAAGTGGGTACCCAGCAGGCACTACGAAGAACCAAAATGATGCTAGCACAGTCCCTGCCTCCTCAGACCATTCAGGACAATGATATGTATGGGAATGAGCAAAGGC
TGATTATGGATGATGGCAGATTAAGTTAACAAGGAGATGTGATGTGACTGACACAAGGCCGAAGAGGCTCCATTTCTGCTGAAACTTGGGGAGGGGGTGGAAACTGCCATGGCAAGCACT
AGGAGTAGGAAGCCCAGGCTTCCCCTTAGCCCTGTAAGTGCAAAGATTCAGAACCCAAAAGAATTGTATTTGAGGAACAGGGAGGAAGAACCAGCCAGAAGGGTTCTAGAGGCCATAGTG
CTGCAAGGCCAGAGAGTATAATGGAAGGTTCACTAAGGCTCTTTAGACAGAAGGCATGATGAAAAAGGACTTCAAAGGGTCACATTGGCCAGGTGTGTTGACACAGGCCTGTAAATCCTG
CACTCAGAAGGCTGAGGCAGGAGGATCACCACAAGCTCAAGGCCAGCATGGGCTACATCTGAGATCAGCCCTTCCCCCTCCCCAACACACTTGTGAAATACACACACTAGGTATCTTACA
GAGTCCAGGTGGGAGTCAACTTGGTTATGTCTAGGATGCTAGTATTCCTTTGCCATGCTTTGGAGGATGGTGGTGGCAATGGTTGTTTTAGAGCCTAGATGGTGAGGTGGTGAATAGATG
CCCTTGTGGAGAAGTTCATAGGGTCTAAGGACAAAGCTGGCATCACAGTCTGTTGTGTGTACCTCTCGTCTGAGCCATATTCTTTGGTTTGTGCAGCTCATCATACATGGCAGCTTTGCT
CTGATCCAGATGCCCCGGTTCCACATCTTCTTCCTGGTCCCTGCAATTATTTATGTGGGGGACAAGCTGGTGAGCCTGAGCCGGAAGAAGGTGGAGATCAGCGTGGTGAAGGCTGAGCTG
CTGCCATCAG
AGGTACAAGCCTGGAGGTTGTGAGAGAACCAGCTTGGCTACTAAGGCAACTGACCAGGCACAAACAGTGTCTGGACCACTCAAGTCTACTGGCCTTGCCCAGTGGGGGCA
GAAGGGGCCTAGAGCCATTGGAAGGAGTAATTCAATGAGAAACGTTCTTTGCTAGATTAGGCCCTGCTTAAGACAGAGAGTGGAGGAGACTGGGCCAGGCTTCCTCTTGCCCTGTGCATC
CCCGGCTCCTCCTCAAGGCAAGGCTCTATAAAGGAATGTCTACTTGTTATCAGAGCTGAGGTTGGAGGAACTTCTGGAGACCATACTGTTGCTGGGTCCAAGGCAACAGTTTCTTGCATC
ATCCCTTCCTAGGAGTGACCCACCTGCGGTTCCAGAGGCCTCAGGGCTTTGAGTATAAGTCAGGGCAGTGGGTTCGGATTGCGTGCCTGGCTCTGGGAACCACCGAGTATCACCCTTTCA
CACTGACTTCTGCACCCCACGAGGACACACTCAGCCTGCACATCCGGGCGGCTGGACCCTGGACCACTCGCCTCAGGGAAATCTACTCACCCCCAACGGGTGACACCTGTGCCAGATACC
CAAAG
AGGTGCCCTGACTTCATAAATCTATTCACTCTTCAATTCCCCCAGCATCTCAGGCTCCCCATTGTACCCTCTTCCACAATCCAGAGACTTGCTGTTCCAGAAAAGACACAGATCC
AACCCCACCCTGTATTTTTCCTGATGTCATATAACTCCCTACCCCTGCCTACTGTTTCCACTTCTGGCTTCAGAATGATGACCAAGCTGAATTTAAAAACCACTGCACTCCCTACAGCTG
TACCTCGATGGACCGTTTGGAGAGGGCCACCAGGAGTGGCACAAGTTTGAGGTGTCAGTGCTGGTAGGAGGGGGCATTGGAGTCACTCCCTTTGCCTCCATCCTCAAAGACCTGGTTTTC
AAGTCATCAGTCAGCTGCCAAGTGTTCTGTAAGAAG
AGGTGAGTTACCAACCCCCATTTGCCTAACAATGACTGCACCTCCTGCTTCCATCCTTGTCTCTGATATTTGGTCAAAGGCTAG
TCAGTCTGAAACCTGGAGAGGGGCAGTGTGTTGGAAAGATGCCAGGGTGTTCTGACGGGCAGAGTTGGTATGCTGATGTCCGTAAGGCCCCCACCCAGTTTCCAAGAGCTCCTTCATAGG
AGTGCCCATATAGGAGTTACTTGTGGGAGTCTCTCCAGGAAAGGCTCAAGGAAGGTAAAACAAAACAAGCAAGCAATGAAACTACATTCCCTCATCCAGAAGAGGCCAGCCCTTGGAGCA
CTGGCTGGGAGAGGGAAGGGTGCCTTTCGGGTGGGGCACAAGTAAAACTGGCTTATGTCTCAGGATCCGGGGGAGGTACCAAGGTAGGACTTGCAGGTAGGTTGGCCCTAGCAACATGGC
CAAGGCTTCAGGCCCCCTTTTCTGTAATTCCGACCCAGTGGCAGGTCCTTGCTTGTCTCTCTGGGCCTGGCAGGTGAATCAGGTGTGCTGGAATGTGGCAGGCAGAGGCCCAGCCTATGC
GTTGCCTGCACTCAGAGGGTGCCAACTCTTCTTCTGTTCCTTCACTTGCAGTACCTGGCTTATCCTCTTGAAAGCTTGAGTTGGCTCCTGCCAGGGAGGCCTCCTTTCTTTTTTTAAATC
ACATTTCAGGCAGCTAAAGATCCCTAGGGTGGCAGCTCTATGAAATGCCTTTCAGCTCAAAAGTTCTGCCTCTAGGCAGCTGCTCACACTAGAATGGGCTTGGCTTGAGGAAGCTGCCTT
GGACCTGACAGACGTTCAGATCAGTGGTGGAAGGCTCTTTGGTGAGATCGCTTCTCACTCACACCACTCTGTCCAAGGGCAAAATACATCTCTGTATTGAGGCTGGCCCTACTTCCTGTA
CATTCTATTTCCTAGGTGGTCTAGGGATAGGAACAGACTAGCTGAGGTCAGAATTCCATGTTGAGATCCAGGATCTATAGGGAAGCCAAGCTGAGCTGGCCCTGAGCCCCAGTGTGTGCC
CTCAGATCTACTTCATCTGGGTGACAAGGACTCAGAGGCAGTTTGAGTGGCTGGCTGACATCATCCGGGAGGTGGAGGAGAATGACCGCCAGGACCTGGTGTCTGTGCACATCTATATTA
CTCAGCTGGCTGAGAAGTTCGACCTCAGGACCACCATGCTG
TGGTAGGTCAGGGCAAGCCAGGCATGGCAGGAGGGCCACTCCCAGGGCCAAGGGTTGTTCCTAGCAATGGCCTTCCTCC
CCCATTTCATTTGCCAGTACATCTGTGAGCGGCACTTCCAGAAGGTGCTGAACAGGAGTCTGTTCACGGGCCTGCGCTCCATCACCCACTTTGGTCGCCCTCCCTTTGAGCCCTTTTTCA
ACTCTCTGCAGGAAGTCCACCCCCAA
AAGTAAGTCTACTTCATATCTTAGTTCTCGGCTCCTTTGATCACCCGAGGACTGAGCAAAGCTCTCAATCCTAGTCTATCAAGGAAACAACTGG
TTACTGCTGAGAAGTCATCTCTTGGGAGACTGGTATGTTACAGACTGGAGAAACATAGATGGAGGGCCACCCTAAGGTAGGAAGGAAGGAAAGACGGATGAAGGGAACAGAGATCTGCCA
ACTCTGAAGTCTAAGTTCATCCACCAAAACAGAAGAGCTCAGTAATAGAAATATTCCTTACTATACAGTCAGGGCTATACTCACCATTAATACTAAGCCAGCTCTCCCCGTGGATGTGGA
ACTAGTTTTCGCCATGAACAGTGAGTGGGCTGGCTGCAGATAACTTATACACCAGGCTGTCCCTCAATTTGAACATTGACTCAGTTGGTCCTTTTACACTGACCTAGCACTTACAAAATT
GAGCTAGACTTACAGTGAGCCAGCCCTCACCATACACGGTATAAAATAAACCTTGAGTGTGAACACTGGATGGTCTTTAATAGGACCATAAAGCTAACCTGCACCAGGAACATGAACCTG
GCTACTGTTTTGAATACTGATCCAGCTCTACCAGTAAATATGTTCATCTTTGGCTCTTCCTCCTTCAACAGGTCCGAAAGATTGGAGTATTTAGCTGTGGTCCCCCTGGCATGACCAAGA
ATGTGGAGAAGGCTTGTCAGCTCATCAACAGGCAGGACAGGACTCATTTTTCTCACCATTATGAGAACTTCTAG

Retrieve as FASTA  
CDS
Send to BLAST
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
ATGGGGTTCCACTTAGCTCTGGCCTGGATTCTCCTGGTTGGGACACTGGCTTCTTTGGGAGCTCAGAACTCCATTTCTTGGGAGGTACAGCGATTTGATGGATGGTATAACAACCTCATG
GAGCACAGATGGGGCAGCAAAG
GCTCTCGGCTGCAGCGCCTTGTTCCAGCCAGCTATGCAGATGGTGTCTACCAGCCCCTGAAAGAACCCTACCTGCCTAACCCCCGACACCTTAGTAAC
AGGGTCATGAGAGGTTCTGCAGGGCAGCCATCTCTTCGGAACCGTACAGTCCTGGGTGTCTTCTTTG
GCTACCACGTGCTCTCAGACCTGGTGAGTGTGGAAACACCAGGCTGCCCCGCA
GAGTTCCTCAACATTTACATCCCGCATGGGGACCCGGTGTTCGACCCTGACAAGCGCGGGAACGTGGTGCTGCCCTTTCAAAGGAGCCGCTGGGACCGCAACACTGGACAGAGCCCCAGC
AACCCCCGGGACCAG
AGCAACCAGGTGACCGGCTGGCTAGATGGCAGCGCCATCTATGGCTCCTCTCATTCCTGGAGTGACACTCTGAGGAGCTTCTCTGGAGGACAGCTGGCTTCTGGG
CCTGACCCTGCTTTCCCATCGGACTCCCAGAGCTCTCTGCTCATGTGGATGGCGCCGGACCCCTCCACAGGGCAGGGAGGGCCACGGGGGGTGTATG
CCTTCGGGGCCCAGCGCGGGAAC
AGGGAGCCCTTTCTGCAGGCTCTGGGCTTGTTGTGGTTTCGCTACCACAACCTGTGTGCCAGGAAGCTGGCGCAGGAGCACCCGCACTGGGGGGATGAGGAACTGTTCCAGCATGCTCGC
AAGAGGGTCATTGCCACCTACCAG
AACATTGCGATGTATGAGTGGCTGCCCAGCTTCCTGAAGCAAACTCCTCCGGAGTATCCAGGATACCGTCCATTTCTGGACCCCAGTATCTCCCCA
GAGTTCGTTGTGGCCTCTGAGCAGTTCCTCTCTACCATGGTGCCCTCTGGGGTCTACATGAG
GAATGCCAGTTGTCATTTCCAGGGGATTCCCAGTCATAACTCAAGTGTCTCTGGAGCT
CTCCGGGTCTGCAACAGCTACTGGAGTCGAGAG
CACCCCAAGCTACAAAGGGCTGAAGATGTGGATGCACTGCTGCTGGGCATGGCCTCCCAGATTGCTGAGAGAGAGGACCACGTGGTG
GTTGAGGACATGCAAG
ATTTCTGGCCTGGGCCACTGAAGTTTTCCCGTACAGACTACCTGGCCAGCTGCCTGCAGAGGGGCCGGGATCTAGGCCTGCCTTCTTACACCAAAGCCAGGGAG
GCACTGGGCCTGTCTCCCATTTCCCACTGGCAGGACATCAACCCTGCACTCTCCAGGAGCAATGGCACT
GTGCTGGAGGCCACAGCTGCCCTGTACAATCAGGACCTGTCTCGGCTGGAG
CTACTCCCAGGGGGGCTTCTGGAGAGCCATGGAGACCCTGGACCCCTTTTCAGCACTATTGTCCTTGACCAGTTTGTCAGGCTACGAGATGGTGACCGTTACTGGTTTGAAAACACCAGG
AACGG
ATTGTTCTCTAAGGAAGAGATCGCAGAGATCCGAAACACTTCCCTACGGGACATTCTAGTGGCTGTCACCAATGTGGACCCCAGTGCCCTACAGCCCAATGTCTTCTTTTGGCTT
GCAG
GAGACCCCTGTCCACAGCCAAGTCAGCTCAGCGCCAAGGGCCTGCCAGCCTGTGCCCCCCTCTTCATTCGGGACTATTTCGAGGGGAGTGGATTTGGCTTCGGACTCACCATTGGG
ACCCTTTGCTGTTTCCCCTTAG
TCAGCCTCCTTAGTGCCTGGATTGTTGCCCGGCTTCGAAAGAGGAATTTCAAGAGGCTCCAGAGACAAGACCGCCAGAGCATCATGTCGGAGAAGCTT
GTAGGGGGAGTGGAAG
CTTTGGAGTGGCAGGGCCGCAATGAACCCTGCAGGCCAGTGCTTGTGCACTTACAGCCGGGACAGATTCGAGTAGTGGATGGCAGGCTCACCGTGCTCCGGACC
ATCCAGCTGCGACCCCCACAGCAGGTCAACCTCATCCTGTCCAGCAACCGTGGACGCCGCACCCTGCTGCTCAAGATCCCCAAGGAGTATGACCTG
GTTCTGTTGTTTAACATGGAGGAG
GAACGGCAGGCACTGGTGGAAAACGTCAGGGGAGCTCTGAAGGAAAATGGGCTGAGCTTCCAGGAGTGGGAACTGAGGGAGCAGGAGCTGATGAGGGCAGCAGTGACCAGGCAACAACGG
GGCCACCTCCTGGAGACCTTCTTCAGGCACCTTTTCTCCCAG
GTGTTAGACATCAATCAGGCTGATGCAGGGACTCTGCCTCTGGATTCCTCGACCAAAGTGCGTGAGGCCCTGACCTGT
GAGCTGAGCAGAGCTGAGTTTGCAGACTCCCTAGGCCTCAAGCCCCAGGACATGTTTGTGGAGTCCATGTTTTCTCTAGCCGACAAGGATGGCAATGGCTACCTGTCCTTCCGGGAGTTC
CTGGACATCCTGGTGGTCTTCATGAAAG
GCTCCCCAGAGGAGAAGTCTCGTCTTATGTTCCGAATGTATGACTTTGATGGGAACGGTCTCATTTCCAAGGATGAGTTCATTAGGATGCTA
AG
GTCCTTCATCGAGATCTCCAACAACTGCCTGTCCAAGGCCCAGCTGGCTGAGGTGGTTGAGTCTATGTTCCGGGAGTCTGGCTTCCAGGACAAGGAGGAGCTGACCTGGGAGGACTTC
CACTTCATGCTGCGGGACCACGACAGTGATCTCCGATTCACACAGCTCTGTGTCAAAG
GTGTGGAAGTGCCGGAAGTGATCAAGAACCTCTGCCGGCGAGCCTCCTACATCAGCCAGGAG
AAGATCTG
CCCTTCGCCCAGAATGAGCGCCCACTGTGCCCGAAACAACATGAAGACTGCGTCATCACCACAGAGACTGCAGTGCCCCATGGACACAGACCCTCCTCAAGAGATTCGACGG
AGGTTTGGCAAAAA
GGTAACTTCATTCCAGCCCTTACTGTTCACTGAGGCACACCGAGAGAAGTTTCAACGCAGCCGCCGCCACCAAACGGTGCAGCAGTTCAAGCGCTTTATTGAGAAT
TACAGGCGCCACATTGGCTGTGTGGCGGTGTTTTACACCATCACTGGGGCGCTCTTCCTGGAGAGAGCCTACT
ACTATGCATTTGCAGCACACCACAGCGGCATCACCGATACCACCCGT
GTAGGCATCATCCTGTCCCGGGGCACGGCGGCCAGCATCTCCTTTATGTTTTCCTACATCCTGCTCACCATGTGTCGCAACCTCATCACCTTCTTGCGGGAGACCTTCCTCAACCGCTAC
ATTCCCTTCGATGCTGCCGTGGACTTCCATCGCCTCATCGCCTCCACGGCCATCATCCTCACAG
TCTTACACAGTGCTGGCCACGTAGTGAATGTGTACCTGTTCTCCATCAGTCCACTC
AGTGTCCTCTCTTGCCTCTTCCCTGGCCTCTTCCACGATGATGG
GTCGGAGTTCCCTCAGAAGTATTACTGGTGGTTCTTCCAGACTGTGCCAGGTCTCACTGGGGTCCTCCTGCTCCTG
GCCCTGGCCATCATGTACGTCTTCGCCTCCCACCACTTCCGCCGCCGCAGTTTCCGGGGCTTCTGGCTGACCCATCACCTCTACATTTTTCTCTACATTCTG
CTCATCATACATGGCAGC
TTTGCTCTGATCCAGATGCCCCGGTTCCACATCTTCTTCCTGGTCCCTGCAATTATTTATGTGGGGGACAAGCTGGTGAGCCTGAGCCGGAAGAAGGTGGAGATCAGCGTGGTGAAGGCT
GAGCTGCTGCCATCAG
GAGTGACCCACCTGCGGTTCCAGAGGCCTCAGGGCTTTGAGTATAAGTCAGGGCAGTGGGTTCGGATTGCGTGCCTGGCTCTGGGAACCACCGAGTATCACCCT
TTCACACTGACTTCTGCACCCCACGAGGACACACTCAGCCTGCACATCCGGGCGGCTGGACCCTGGACCACTCGCCTCAGGGAAATCTACTCACCCCCAACGGGTGACACCTGTGCCAGA
TACCCAAAG
CTGTACCTCGATGGACCGTTTGGAGAGGGCCACCAGGAGTGGCACAAGTTTGAGGTGTCAGTGCTGGTAGGAGGGGGCATTGGAGTCACTCCCTTTGCCTCCATCCTCAAA
GACCTGGTTTTCAAGTCATCAGTCAGCTGCCAAGTGTTCTGTAAGAAG
ATCTACTTCATCTGGGTGACAAGGACTCAGAGGCAGTTTGAGTGGCTGGCTGACATCATCCGGGAGGTGGAG
GAGAATGACCGCCAGGACCTGGTGTCTGTGCACATCTATATTACTCAGCTGGCTGAGAAGTTCGACCTCAGGACCACCATGCTG
TACATCTGTGAGCGGCACTTCCAGAAGGTGCTGAAC
AGGAGTCTGTTCACGGGCCTGCGCTCCATCACCCACTTTGGTCGCCCTCCCTTTGAGCCCTTTTTCAACTCTCTGCAGGAAGTCCACCCCCAA
GTCCGAAAGATTGGAGTATTTAGCTGT
GGTCCCCCTGGCATGACCAAGAATGTGGAGAAGGCTTGTCAGCTCATCAACAGGCAGGACAGGACTCATTTTTCTCACCATTATGAGAACTTCTAG

Retrieve as FASTA