The peroxidases and oxidases database
Entry information : MmDuOx01 ( DUOX1/Duox2/ LNOX1/ LNOX2/ THOX1/ THOX2/ NOXEF1/ NOXEF2)
Entry ID 3342
Creation 2006-07-18 (Christophe Dunand)
Last sequence changes 2016-02-16 (Christophe Dunand)
Sequence status complete
Reviewer Achraf Jemmat
Last annotation changes 2016-02-16 (Achraf Jemmat)
Peroxidase information: MmDuOx01 ( DUOX1/Duox2/ LNOX1/ LNOX2/ THOX1/ THOX2/ NOXEF1/ NOXEF2)
Name (synonym) MmDuOx01 ( DUOX1/Duox2/ LNOX1/ LNOX2/ THOX1/ THOX2/ NOXEF1/ NOXEF2)
Class Dual oxidase    [Orthogroup: DuOx001]
Taxonomy Eukaryota Metazoa Chordata Mammalia Muridae Mus
Organism Mus musculus (house mouse)    [TaxId: 10090 ]
Cellular localisation N/D
Tissue type N/D
Inducer N/D
Repressor N/D
Best BLASTp hits
Perox score E-value MmDuOx01
start..stop		 S start..stop
RnoDuOx01 3075 0 1..1551 1..1551
PtroDuOx01 2891 0 1..1551 1..1551
HsDuOx01 2884 0 1..1551 1..1551
SscDuOx01 2870 0 1..1551 1..1553
Gene structure Fichier Exons►
ExonStart..EndSize ExonStart..EndSize ExonStart..EndSize ExonStart..EndSize
N° 1 1893..1950 58 N° 2 4109..4192 84 N° 3 4578..4742 165 N° 4 5627..5814 188
N° 5 5977..6178 202 N° 6 6333..6499 167 N° 7 6900..6960 61 N° 8 7052..7148 97
N° 9 9410..9500 91 N° 10 10219..10321 103 N° 11 10542..10714 173 N° 12 12173..12348 176
N° 13 12609..12727 119 N° 14 13269..13406 138 N° 15 14050..14163 114 N° 16 14880..15079 200
N° 17 15732..15917 186 N° 18 19201..19426 226 N° 19 19592..19685 94 N° 20 19893..20068 176
N° 21 22026..22095 70 N° 22 22480..22605 126 N° 23 23442..23620 179 N° 24 23779..24009 231
N° 25 24507..24606 100 N° 26 24815..24864 50 N° 27 26265..26392 128 N° 28 30255..30408 154
N° 29 30769..31001 233 N° 30 31232..31390 159 N° 31 32438..32593 156 N° 32 32688..32816 129
N° 33 33460..33582 123  
join(1893..1950,4109..4192,4578..4742,5627..5814,5977..6178,6333..6499,6900..696 0,7052..7148,9410..9500,10219..10321,10542..10714,12173..12348,12609..12727,1326 9..13406,14050..14163,14880..15079,15732..15917,19201..19426,19592..19685,19893. .20068,22026..22095,22480..22605,23442..23620,23779..24009,24507..24606,24815..2 4864,26265..26392,30255..30408,30769..31001,31232..31390,32438..32593,32688..328 16,33460..33582)


exon

Literature and cross-references MmDuOx01 ( DUOX1/Duox2/ LNOX1/ LNOX2/ THOX1/ THOX2/ NOXEF1/ NOXEF2)
Literature REFERENCE 1 Cheret,C., Gervais,A., Lelli,A., Colin,C., Amar,L., Ravassard,P., Mallet,J., Cumano,A., Krause,K.H. and Mallat,M. Neurotoxic activation of microglia is promoted by a nox1-dependent NADPH oxidase. J. Neurosci. 28 (46), 12039-12051 (2008)

REFERENCE 2 Rigutto,S., Hoste,C., Dumont,J.E., Corvilain,B., Miot,F. and De Deken,X. Duox1 is the main source of hydrogen peroxide in the rat thyroid cell line PCCl3. Exp. Cell Res. 313 (18), 3892-3901 (2007).
Protein ref. UniProtKB:   Q8BZ02 [3' end]
DNA ref. GenBank:   NC_000068.7 (122313811..122349226)
mRNA ref. GenBank:   AK037033.1
Cluster/Prediction ref. Genebank:   99439 UniGene:   Mm.108582
Protein sequence: MmDuOx01 ( DUOX1/Duox2/ LNOX1/ LNOX2/ THOX1/ THOX2/ NOXEF1/ NOXEF2)
Sequence Properties
first value : protein
second value (mature protein)
Length (aa):   %s   1551 (1530)
PWM (Da):   %s   176872.36 (174737.2) Transmb domain:   %s   o594-616i1044-1066o1081-1103i1149-1171o1186-1208i1221-1243o (o573-595i1023-1045o1060-1082i1128-1150o1165-1187i1200-1222o)
PI (pH):   %s   8.56 (8.56) Peptide Signal:   %s   cut: 22 range:22-1551
Sequence 2398
Send to BLAST
Send to Peroxiscan
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MGFHLALAWILLVGTLASLGAQNSISWEVQRFDGWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLKEPYLPNPRHLSNRVMRGSAGQPSLRNRTVLGVFFGYHVLSDLVSVETPGCPAEFLNIYIPHGDPVFDPDKRGNVVLPFQRSRWDRNTGQSPSNPRDSNQVTGWLDGSAIYGSSHSWSDTLRSFSGGQLASGPDPAFPSDSQSSLLMWMAPDPSTGQGGPRGVYAFGAQRGNREPFLQALGLLWFRYHNLCARKLAQEHPHWGDEELFQHARKRVIATYNIAMYEWLPSFLKQTPPEYPGYRPFLDPSISPEFVVASEQFLSTMVPSGVYMRNASCHFQGIPSHNSSVSGALRVCNSYWSREHPKLQRAEDVDALLLGMASQIAEREDHVVVEDMDFWPGPLKFSRTDYLASCLQRGRDLGLPSYTKAREALGLSPISHWQDINPALSRSNGTVLEATAALYNQDLSRLELLPGGLLESHGDPGPLFSTIVLDQFVRLRDGDRYWFENTRGLFSKEEIAEIRNTSLRDILVAVTNVDPSALQPNVFFWLGDPCPQPSQLSAKGLPACAPLFIRDYFEGSGFGFGLTIGTLCCFPLVSLLSAWIVARLRKRNFKRLQRQDRQSIMSEKLVGGVEALEWQGRNEPCRPVLVHLQPGQIRVVDGRLTVLRTIQLRPPQQVNLILSSNRGRRTLLLKIPKEYDLVLLFNMEEERQALVENVRGALKENGLSFQEWELREQELMRAAVTRQQRGHLLETFFRHLFSQVLDINQADAGTLPLDSSTKVREALTCELSRAEFADSLGLKPQDMFVESMFSLADKDGNGYLSFREFLDILVVFMGSPEEKSRLMFRMYDFDGNGLISKDEFIRMLRSFIEISNNCLSKAQLAEVVESMFRESGFQDKEELTWEDFHFMLRDHDSDLRFTQLCVGVEVPEVIKNLCRRASYISQEKICPSPRMSAHCARNNMKTASSPQRLQCPMDTDPPQEIRRRFGKKVTSFQPLLFTEAHREKFQRSRRHQTVQQFKRFIENYRRHIGCVAVFYTITGALFLERAYYAFAAHHSGITDTTRVGIILSRGTAASISFMFSYILLTMCRNLITFLRETFLNRYIPFDAAVDFHRLIASTAIILTVLHSAGHVVNVYLFSISPLSVLSCLFPGLFHDDGSEFPQKYYWWFFQTVGLTGVLLLLALAIMYVFASHHFRRRSFRGFWLTHHLYIFLYILIIHGSFALIQMPRFHIFFLVPAIIYVGDKLVSLSRKKVEISVVKAELLPSGVTHLRFQRPQGFEYKSGQWVRIACLALGTTEYHPFTLTSAPHEDTLSLHIRAAGPWTTRLREIYSPPTGDTCARYPLYLDGPFGEGHQEWHKFEVSVLVGGGIGVTPFASILKDLVFKSSVSCQVFCKKIYFIWVTRTQRQFEWLADIIREVEENDRQDLVSVHIYITQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSITHFGRPPFEPFFNSLQEVHPQVRKIGVFSCGPPGMTKNVEKACQLINRQDRTHFSHHYENF*

Retrieve as FASTA  
Remarks omplete sequence from genomic (Chromo 2, 32 introns), mRNA and 28 ESTs.
DNA ►
Send to BLAST
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
ATGGGGTTCCACTTAGCTCTGGCCTGGATTCTCCTGGTTGGGACACTGGCTTCTTTGGGTGAGTATTAGAGTTGCAGAGGAACCAAGGTCTTTTGGTCTTTTCCAAAGACATGCCAATCA
TTTCTGCACCCTCAAGCAGATATAATACCCTGTATATACCAGGTGCTTGTTTCAAGCTATTGAGCAAATGGGTAGACAATAGAATGAAAATGGTTTTTTCTGGTGTGGGTCCCTTTCTCT
CTCCTCTGTCTTCTATCCTGTTTTGTGAGGTAAGTTCTCCTGATGTGAAATAGGAAAGACTGAGTAGACACTTAAGACAGTAAAGCTTCCTGAAGTAAGCTGAAAAGGACTCACCAGTGT
TTTTAAAATAAAATGATCTTGGAACAGGGGATACTATTTGGTGATAGAGCACTTGCCCAGCACATATGAGGCCCTAGGTTTCACCCCCAGTGTTGAATAAAAAAAAAAAAGCACAAGATA
AGATAATAGCATCAGAGCACAGCAATTCCAGCTTTGGAAGTCTGAAGAGCTTTAGAATCGGTGGGTATTCGCTGTCGTGTAGGGCTCTGAAGAGGAAAGTGGCCGCATGATATTAAGGTT
AGGTTTAGAAAAGCAAGCTTCTATCCAGGTATAGTGGCTCTGCCAGCACTTTGGAGGTAGAGGCAAGAGGATCAATAATTTAAGGTCGTCTTCCAGTAGATGAGTTCAAGGTCAGTCTGG
GCTTGAGACTTTAAGACTGTCTCAAAACAAACAAGCAACAGCAAACCTTGAAAGTCTTTTGCATCTTGGAAGATGATAAATGAAGATGACCCTTCTGGCTGGCAACGGCGAGATAGTGAT
ATGAACCCTACACTTCTCCCTTGCCAAAGACGCCCACGGTTCAGTTCTTTCCAGTACTTTCCCTTCCTGGGGCTTCATTTTCTGTCCCAGTTGGTACCTCTTATGCCCAAGATATACTTT
CTCCAAAGGCTACTCCTGCCCTTGACCTGCTTCAGTTCATTTTATTTTGGAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTCTTACTGCCCTAGATCCTT
AGCCAGGTGAAGCCACTTTCCTTCCTGATGGATGTATGTGCACCTTCATGTGTCAGTGAGGGCACATGTCACCCACAACTTGAAAATCCTATCTTTGGTCTAAGGACATTCAGAGCAATG
GGGCCCCTCTTACTTTCTTCTCTTCTCTCAGTTGAGTAGAAAAGAAGTCTTCTAGTTGTTTTTTAGAGGGGCGTGTTTGGCTGGTCACCTGATCTACTAACCAAGAGGATTCCAGACCCT
TCCTTCTATCCTGCGTTCTCAGCAACCCCCTCCCCCAACAGCTGAGTGTCCCTCTTGGGCTGTGAGTTTTTAGAGCAGCATCATAAACAGGAATTGGGGTTGGAGAGAAGGCTCAGCAGT
TAAGAGCACTGGCTGGCTAGAGGACCTGGGTTCAGTTCCCAGTATTGGCGTGGCAGCTCATAAATGTCCCTAACTCCAGTTCCAAGGGGTCAATAGCCCCTGTGCACATCAGGCATGCAT
GTGGTACTTCGGCATACATGCATGCAAAACACCCATACACATGAAATAAATAAATCTTAAAGAAAGAAAGGAAGGAAGGAATGAGATGAGTGACAAAATGTTCCAATGGAGGACGGATTC
AGTCATTCACAGAATCAGTCCTTAGTCTCACCCAAGAAACTGGCAAAAAGACCAGAGTAGCAGTGACACGCCCCTGCCTTGGGGCTCTGCTTAGTGGGAAAGAGCCAATCCCCTCTTCAC
ATTGCCCCTGCCCAGTGACAGGTCACAGAATGACTTGGCCTTCCTAGTTATAGGGTGTGGCTGGCTCTTGTTCCAAGTGGTAGCTATCCGACAGCTGGGAATGACGTTTGTCCTGGTGTG
CCTCTGGAGGACTTGAGATGTGAGGAGACTCCAGGCTTCTGCATCCTCTACTGGATTGTCACTGTTTTCTCTCCTCTCAGCTAAGACTGTTTGTCAGCAGGCACTGCACGCTCATGCACC
ATGTTCCACTTTAGGAGTCTTCCTCACTGGGTGCCTTGAAGAATAGGCTTGAGTTTAGAAAATACTTTGCCCTTGTTTCTCCCCCTTATTGGAAATCACAGGACCCGTTCCCTCATGGCC
TGCTTGGTCTCCCCTGCACCCACTTGCCCAGTTACCTTTCCTCTGTCTTCACACAGGAGCTCAGAACTCCATTTCTTGGGAGGTACAGCGATTTGATGGATGGTATAACAACCTCATGGA
GCACAGATGGGGCAGCAAAGGTAGGTGAGAGCACAGCCCAAGGGCCAGGGCGGTACTCACCAGTGGAGAGTCAGGGCTGGCAAGTATCACAAGAGGCTATCTCAAGTATCACCAAAGGCT
GCCAACATCTAAGGCTTTAGAGTTCAGTGTATGGAGGGACAGAAGAGGACAAGAACGCACTTGAGGTACAGACATTGCTAAGTGGTTAAGAGTACATGCTGCTCTTACCGAAGACACAAG
TTCAGATCCCTGCATCCATTTCCAGTGACTCATTGTTACCTGGAACTCGGGGTCTAGGTGTTCTGATGCCTCTGGTCTCTGCAGGCTCATACACTCTCATTCACAGACACACAGACAAAC
ACTCACAATTGAAATTCATCCTTGTCTTTACCTCTCCTATGCCAGGCTCTCGGCTGCAGCGCCTTGTTCCAGCCAGCTATGCAGATGGTGTCTACCAGCCCCTGAAAGAACCCTACCTGC
CTAACCCCCGACACCTTAGTAACAGGGTCATGAGAGGTTCTGCAGGGCAGCCATCTCTTCGGAACCGTACAGTCCTGGGTGTCTTCTTTGGTGAGAGCTGTAGTGGTTGGGGGGTGGTTC
TGATGTTTTGATTGGGAAACTGAGTTTACACGTGGGAATGGTCGGCCAGGAACAAAAGCAATATAAACAAAACTACTTGCTACAGCAAACCTCAGCCCTTGGGGGAGCTTAGCCAGTGGG
AGTCAGATGGACATTTCTGCATCTAAGGACTCAGGGGATGAGAAAAGATACTAAGGAGGATCAAAGATGGGGGTGAGAGATGGAAGAGGAAGCCATTAAAAAGGATAGGAGTAAAGCAGG
TGGGGGCAGGGCATGCTGAAGTGAGGTCTGACAGGCATGAATCTACCTTGTGCTGGTAGGGCGTCCTCCATTTGGGGGGAGGGTTGGGGTACAGACTTGATAAACTGTCCCTAGGACACT
GATGCTCCTAGAACATACCAAGAGAAGAGTCCTAGCTGCGGCAGAGAGGGCAATATGGGGGCCTTATGGTGTCATAAGCTCAGTGACAAGGGGTCCTGCCGCAATGATGGCTCCTACAGG
CCATGTTGGGTGTCCATGCTAGCTCACATGTGACTTCCTGCTTGGCTACAGGCCTTCAGGGAGGCTCCTAGCTGCATGTTGGAGCTGGTGCCCACAACCCTGCCTACTGAGGCGTCATCT
CTGAACACCTCCCAGTTACCAAGGAGAATGCCAAACTGACAATGACAACATCTTAGAGCAGGTGTAGGCACAGGCAGGCCAAGAGAGACAGAACCAGGAGGGAATGTGGAGGTCAGGGCT
TGGATTTGCCCATAATAGGAAATGACTGTTCTGAAGCTTCGAGTAGGGGGCGGGCGTGTCAGGGACTCCATACCTGAGGCAGGGATGAGCATGGCCGTAGGCTGGCCCAGCAAACCCTCC
TGCATTGTGGGCAGGCTACCACGTGCTCTCAGACCTGGTGAGTGTGGAAACACCAGGCTGCCCCGCAGAGTTCCTCAACATTTACATCCCGCATGGGGACCCGGTGTTCGACCCTGACAA
GCGCGGGAACGTGGTGCTGCCCTTTCAAAGGAGCCGCTGGGACCGCAACACTGGACAGAGCCCCAGCAACCCCCGGGACCAGGTGAGGCCAGGCAGCCAAAGGCAGGAGGGCAGAGAGGC
GGGAAGGGGGTCTGAGGCTGGATCCGCTGGAGGCCTGGGATCTGGCTGGGAAGACCAGACACGATGAGGCTCTCCCTACCAGCAAGGACCTGCCTGGTCCTCCTGACTCTGCTCATCCCT
GCAGAGCAACCAGGTGACCGGCTGGCTAGATGGCAGCGCCATCTATGGCTCCTCTCATTCCTGGAGTGACACTCTGAGGAGCTTCTCTGGAGGACAGCTGGCTTCTGGGCCTGACCCTGC
TTTCCCATCGGACTCCCAGAGCTCTCTGCTCATGTGGATGGCGCCGGACCCCTCCACAGGGCAGGGAGGGCCACGGGGGGTGTATGGTGAGACTGCGGGGTCCTGGTAGGAGGGGTAGGG
TTAGAGGCACCAGGCTGCTTTGGGGTCCTGTACTGGAGAAGGGGCAACTGACTGTGGGTCTGGGCTCCCCTGACTCAAGCTGTTGTCCATCTCCTGTCCTGCTTCCCCACATGGATGCAG

CCTTCGGGGCCCAGCGCGGGAACAGGGAGCCCTTTCTGCAGGCTCTGGGCTTGTTGTGGTTTCGCTACCACAACCTGTGTGCCAGGAAGCTGGCGCAGGAGCACCCGCACTGGGGGGATG
AGGAACTGTTCCAGCATGCTCGCAAGAGGGTCATTGCCACCTACCAGGTGAGTCGTGCCGCCTGCCTGGAGTCCACCTGTGTGTAGGGTCCAAAGAGACTCTGCACCCCCAACAAAGCTT
CCAGGATCCTGGACAACGCCCCTTTCCTACCTAGCCCTTTCCAGGAGGGCTCTTCTCCAGGGAGAGCTAGTATCTAGGAAAAACTACTATATATGATATAGAGGCAAAAATGGGTTTATG
CCAGATTATTTGGGAATTGATCATTACTTAACATCTCTTTCTTCTCAGTAAGTTCTATGAAGAGCCTAGCACTTGATGCTGTTGTTTTGAAGGCCTTTTCTCCCATGACCAGCCTTTGCT
GGTCCTCGTGTCTACCTGTAAGCCTTCCCTGGGCCCCTTCCTCAGGGCTAGTCCTACACACGTGCCTTTTTACCTTTTGATCCTCAGAACATTGCGATGTATGAGTGGCTGCCCAGCTTC
CTGAAGCAAACTCCTCCGGAGTATCCAGGTGAGGAGGTGGGAAGGAGGGCTGAGAAATTGTGAAGTGTCTTTTAGTGTGGATTTAAACCTTCATGTGTCTGTTTCTCCTCTTACCTCAGG
ATACCGTCCATTTCTGGACCCCAGTATCTCCCCAGAGTTCGTTGTGGCCTCTGAGCAGTTCCTCTCTACCATGGTGCCCTCTGGGGTCTACATGAGGTAGGAGAGGAAGCTCACATATTT
GTATCTTGGACTCATTATTGATAAAAATCTGCCTTCAGGAGTTCTCAGGACAGGATTACATCAATTCAGAGCAGCTAGTTTCTAGAGAGAATGGTGAAAATGGAGGGAAAAGGTGGTCTG
TTTTTAAATAGACCATTCATTGTGCATGGCGTTGGTTATCCATGATCATGTGATTTGCTTGTATGTGTTTGGTCAATGGCTTTTCAAGATAGGACTATGTAGCCCTGGCTGGCCTGGAAC
TTGTCAAGATCCTCCTGCCTTTGCCTCCCATGTAGCTTGACTACAGAAGTACACCTTTGACGGATTAAAAGAAAAAAATGTTTATGGTCTTTAAAAATGTGTATATGTGTATGTAGCTGG
GTGGTGGCTCACACAATTTTTTGTTTTGTTTTGTTTTTTTTTTTGAGACAGGGTTTCTCAGTATAACCAGGCCTGACCTTCCTGGACTCCTTTTGTTGACTAGGCTGCCCTTAAACTCAT
AGATATCCACCTGCCTCTGCTTCCAGGGTGCTGGGATGAAAGGCACGTGCCACCGTGGGAGGCTGTAGTTCAGATCTTTAATCCCAGAACTCAGGAGGCAGAGGCAGGCAGATCTCTGAG
TTCAAGGCCAGGCTGGTCCATAGAATGAGTTCTAGGACAGCCAGGGCTGAAGAAAACCTATCTCAAATAAAAACAAAACCACTCCACAAAACCAAACAACAACAACAAGAAACAAAAAAC
CCATTAAACCAACAAAAACAATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATGTAGTTGCTTCCAGCCGCTCACGTCCTTAAAGTTTTTTCACCTGCTTGGG
AGGCTGATGTGGGAGAATTAGCTTGAGCTCAGAAGGCAAATGGAAAACTTCATCTTGAAAAAAAAGGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAAGTGCATGTTTATAGTCTCTAGTC
CCAGCAGGTAAGAGTCAGGAGAATAGGAGTTCAAGGTTATTCTTTACTACACAGAGAATTCAAGACCAGTCTGGGTTACTTGAGACCCTCTCTCAAATAGAGACTACACATACATATAAA
TAGAATTCTATAGGTGATAGGTACATAATACAAGTGTGTGTAAGTGTGTAATCTATATAAGTAAGCTATTACATGTCAGGCTTCCTATCTACCCAGTCAAACTCAGATTTTAAGTATCTG
AAAACGTAGATGTTTTAGAGCCATTCTTCCTGAAATAATAAACTCTAGTGACTATTTAGATAGCATTTATGTTATATCAAGTATTATAAGAATATGGGTTGGGGAGGTAGCGCAGTTAGT
AAAGTACTTGCCACTCAGGCACAAGGACTTGAGTTCAAGGGTTCAAGTTCTAGCATCCTATAGGAAGTCAGATGTAGTGATTCTGGCTTGTAATTCCAGTGCTGAGATGGTAGAGACAGG
TAGATCCCTTGGGCTGGCTGGTTTGTCAGTCCAGCTTAATTGTCCCAGGTCCCAGTGAAAGACTCTCAAAGCAAGCAAGCAAGCAAGCAAGCAAGCAAGCAAGCAAGCAAGCAAGCAAGC
AAGCAAGCAAACAAACCAACCAAGGTGGAGAACTTCCAAGGACTGACACCTGAGCATAACTTTTGGACTCCACATGTACCTGCACCCATATCACACACACACACACACACACACACACAC
ACACACACACACACACACACACACACACACACACACACACACGTGCGCGCGCGTGTGTGTGTGTGTGTGTGTGTATGTAAAAACATCCAAAGACTTGGATATTACTGTATGGACTAATGT
GCATAGATTATAGGCAAATATTATGCCATTTTAGATAAAAGATCTATATATCCATGGATTTGTTATTGGTGAGGGTCTTAGAACCAGTCTCCAGTGTCCTCCAAAGGACTCCTATCTGTG
TGTGAGACTGCTTTCTTTCTGTGTGTTCTTATCCACGTGGAGACAGTGTGGATAGAATTTTTTTAATGGCCAAATTTTCAGATGTGTGATCAGATGGGAGGTAGGAATCTTCTGAAAGTC
AAATTATTCAATAGCTATCAAGGTCTTGATTACACAGCAGATAAGGGAGGCTTATGGCCTGGGACCCCTGGCTGATTACAAAGCAGATAAGGGAGGTTATGGCCTGGGACCCCTGGCTGA
AGTCTTACAAACCAAAGCTGACGCCTGACATTAGGATCCTGTGGTCTCTGTAACCATTCTTGCTCCTTGCACTTTAGGAATGCCAGTTGTCATTTCCAGGGGATTCCCAGTCATAACTCA
AGTGTCTCTGGAGCTCTCCGGGTCTGCAACAGCTACTGGAGTCGAGAGGTCAGAGTTGGAGATACTATTGGATTGATAAATGCATGTGTTGTATATGTTGCATGTGTATATATCTGAGTG
TGTGAAGGGGGTGGGCACTAGGGCTGAAGTAGCAGCTCGGATGGGTTAGAGAGTGGGGAACAGCTTGGGGACATGATCAAAAGTCAACTCCCTATCCTCAGCCAAGGGCTGCATATGAGA
GACAGGAGGGGAGGGGGACTGTGTGTTCAGGTGTGCTTCCACATTTACTGTTCTTCTTAGGTGTCTCCCTTGACAACTCTGGGCCCCTGGAGACTTTGGAGCACCCAGCTAAGCTATCCC
ACCTAGACAATTGTCTATACACCCCTAGCTTGGGCCTCTCTTCTAGTAAAAGGAGAGCAGCAAGTTCAGACAGGCCCTATGGCTTCTGCAGGACCACACCACTGGTTGATGGGAGAGCAA
AAATGAGCATCTAGATGCTCTAGTGTCCTTGCTAGTCATATGGTCAAATCTCCTGGGAAAGAATAAAAGTTAAAACAATAAAAAATAAAATAAACCCTGTGCTCCAACACATCGGTTTTG
GGTGGGCATATCATTTACCATGAGTGCAGAATTAGCCTGAAGTTGAGAAACGCTCACCAGGGGCTAAGAACATGACAAGCCCAGGATGTGGCACAAGTGGCAGAGGGAGCCAGGAGCCCA
AACCCTGGTCCTGTTAGCCATGTCTGTCTTCTCACCACTCCTTAAGCACCCCAAGCTACAAAGGGCTGAAGATGTGGATGCACTGCTGCTGGGCATGGCCTCCCAGATTGCTGAGAGAGA
GGACCACGTGGTGGTTGAGGACATGCAAGGTGAGCCTGAGGCTGGCCCTGCAGGCTGTGAACTTCTGACCGCTGGGAGGAGATCCTGCTGAACCTGCAGAAGCAGGCAGGGAGGAGTTCT
CAGGGCTGAGAGAATCTCTGATCCTCGAATCATGGTTCAGATATTTCTGGGATTGGTTAGAATGGTCTGGGCTGGAGGCTGCAGTGATGGCCCTCAACTCCCTCTAACTCTTTAGTGTTT
CTTTTTCAGATTTCTGGCCTGGGCCACTGAAGTTTTCCCGTACAGACTACCTGGCCAGCTGCCTGCAGAGGGGCCGGGATCTAGGCCTGCCTTCTTACACCAAAGCCAGGGAGGCACTGG
GCCTGTCTCCCATTTCCCACTGGCAGGACATCAACCCTGCACTCTCCAGGAGCAATGGCACTGTGAGGAAGGGTCAGGACCCAGAGGGCTGGGGAGGGGCTGGGCACACTGCCCAAACAG
GGGAAGGTGGGTAGTAAAACATGGGTGCCAGAGTCTAACACTTGGTGAGAGGACAAAACTCACGCAGGTCACGTTTTTCAGTCTTAATTTGTTCCTAAGTCAAGGACCTGCAATGTCCAC
TATAGGATTGTTAAGAGTAACAAAATCAATGTCTACCAAGTTAAGTGTGTGGCAAGCAACAGGTAGTTAATACATATTTACTGGACCTGGGCCTTCAGAGTCAAAGGGCAAACCCTGCTG
GACTTGGAATCTCTTAACTTGGTGTACAAGTTATAAACTTGTAAAGCCTACAGAAACATAGGGATTGTGAGAAAAGTCAATAGGAAGTCTTTGGCTTCAGTTAGGTGTCATTGGAACGAG
CCTGGTCAGGGACTTAGGGACAAGTAAAGAACAGGAGGTGTTAAGATGACTCGGCTGGCATTTGCAGCCAAGCCTGACAACCCGAGTTTGATCCCCTGCAGAATCCTCATGGTGGAAGGG
GTAAACTAATTCCTTAAAGTTATCCTCTGGTCTCTACATGTGCACGTAGTGTACACATTCACACACACGCACACACACACACACATACACACACACCACACACATACACACCACACACAC
ACATTCACACACACGCACACACACACACACACACACACACACACCACACACATACACACCACACACACACACACACACACACACACATTCACACACACGCACACACACACACACGCACAC
ACACACACACACACCACACACACACACACACACACACACACCACACACACACTCACACACCACACACACACACAGACACTTCACACACACATAAATGTCATAAAAATTAAATTAAAACCA
GAGTAGAAAACTCTGGTAGTGGGTGAGGTGTCAGAGACAAACCCTCACGTGAGACAGCCATATCTCTGTCCCAGCACATGGGAGGCAGAGGCATTTCCAGGCTAGCCTGGTGCAGAGTGA
GACTCAACTTCAAAACAAACAACAATGATGTATAGTCAGATTTTTAAAAAAATACTCTCACTGTGACCACAAACTGGGAGGGATTTAGTTGTTTAAAGTTTTTTTTTTTTTTTAACTCTA
AGGATAAAAGCCTTTTATAATATCATTCCGGCATTCAATCTTTCACAGTCTGACTTGCTTCTCAGGCTCCACATCTTCCATACACTATATGGAGGACTGGCTATTGTTTCTTGTGTCTTG
TTTTGTTTTAATTTCATAGAATAGGAATTGGGATGTGTGGAAAGCTTCCTGTAAATGAGTTAACTGAGCAGTGCCTGGGGTGTAACAAGCACTCTCTAGGAATGAGTTCTTTGTTGTTAT
TGGCCCAGGGGCTAATGTCTGGGAGCTGCCTCTTGCCCAGGACTTGTTGCTGAGTACCTCTCAAACACCCTCTGTTCCAGGTGCTGGAGGCCACAGCTGCCCTGTACAATCAGGACCTGT
CTCGGCTGGAGCTACTCCCAGGGGGGCTTCTGGAGAGCCATGGAGACCCTGGACCCCTTTTCAGCACTATTGTCCTTGACCAGTTTGTCAGGCTACGAGATGGTGACCGTTACTGGTTTG
AAAACACCAGGAACGGGTAAGGCTTGCCTGGGCTGTGTCTTAGAATCTACTGTGACCTGGACCACAGGCCCTCTGCTTGGCCCTCCCTGCCCTCACAGGCCTCAATCCTAGCCCCTCTGG
GTCTCTCGAGTGAGGATTAGTCTCTGATGGCTCTCCAGGCTGGCAGGCTCTTACAAACAGCTATGGACCAGAGTCTCTGTCCCCATGGGATACCTGAGTGTGAGGCCCCAAATCTCTCCG
TAACCCTGACAGTTCCTTCACCTCTCCTATGTCCAGATTGTTCTCTAAGGAAGAGATCGCAGAGATCCGAAACACTTCCCTACGGGACATTCTAGTGGCTGTCACCAATGTGGACCCCAG
TGCCCTACAGCCCAATGTCTTCTTTTGGCTTGCAGGTATGTTACCTAGAGGTAGCTGGCGGGGCGTGGGTCCAGAGTCTTGTCCTTTCTTAACTGTAGGCTTGGTTTGATGTGGCTGGAT
GACCCCTCTAAGTTCTGCCCATGAGAAATTTGATTCTAGGTGCCAGGGTTGCCACATACAGTTTCCCTTTGCACAAGTGTACTAGATGCTGAATTAGGGGCAGGGCCAACTCTCTTAAAG
ACCTGGGGGAGACTCTTACATTCAGATGGAACGGGATAGGACTGTGAGTGGCATCCAGAGGGCCAAATGAGGGTAAAGAATATAATATTTCACAGCAGTGCTAACAAAAAGATATAGGGG
CAGGGCGGGGTTAGAGATATTGAGGTTCATGCTGGGACCTGCTTGCTATCCACATAGGCAAATGCCATCATCTTGCTGCAATGACAGGGGTAAACAGCCCCATCCTCTCTAGTTCCCAGA
GCACCCTCACCTCCTCTGTTAATACCCTCTTCAGTGACCTTGTGACAGATTGTGGCATAATAGTACTGGATACTCCGATTTCCTCTGCCTCCCCAGGAGACCCCTGTCCACAGCCAAGTC
AGCTCAGCGCCAAGGGCCTGCCAGCCTGTGCCCCCCTCTTCATTCGGGACTATTTCGAGGGGAGTGGATTTGGCTTCGGACTCACCATTGGGACCCTTTGCTGTTTCCCCTTAGGTAGGA
GAGTAATGGGTAGGCAAGGTGGTGCTATTGAAAGGTGTAGTCTAGTGGGTGTTTTTATGCATAACAACAAAACAATGTAGAGTACTGTCTCTCTGGTGAGAAAAGCATTAGGGAAGGCAA
AGGTGTCTGGCTATAGATAAGTGAACTCCAGGGAGATTTGCTTCCCTGATCTTTTGGGATGCCCCCGGCCTAGCTTGGTCAAGAGTCCATAAGAGTCCCTGGTCTACTGCTGTCTGTGAG
AGCCTGCTAGCCTAGGGACCTATCAGAGACAATTCCTCAGCTGAGAAGCAGCTGGGACAGACTCAGTTTCTGGAACAGGAGCATGGGAAGGTTGTGTGAGGGTGGCCCAGCAGCCTGGTG
TGGTGCATCTAGCTTGTGGTTTGAGGAATCTGGATTTAGTTTCTGGCCGGGAAGGGACTTGAGTAATGGAAGCAATGGTGGCTGATATTTTAGACACTACCCAGAGCTTTCCATGGGTGG
CAACGTGCTCCCTCCACAGAGCCTCGATATTTGAAAGTTGGGCAGCTGGAGGGTCAGAAGTTAGGAATAGAAGGAGCTCTTCTGAAGGAAATGAGGGAGTGACTTTTCTCTCCGATGACC
ACTTTTCCCTGAACATCCCTCTCCACTCTCACACCAGTCAGCCTCCTTAGTGCCTGGATTGTTGCCCGGCTTCGAAAGAGGAATTTCAAGAGGCTCCAGAGACAAGACCGCCAGAGCATC
ATGTCGGAGAAGCTTGTAGGGGGAGTGGAAGGTAGGCCATGGGGTAGCCAGGGCGGTGCTGGGAAGGTCATGACTTGGGGCTATGATCCATACCCCACCCCCAAGTCCAAGGCAAAAGAT
CCTCATTTCCAGGGATGTAGGAAAAGCCTGAGCAGGTTGGGGAAAGCCATGGTAGACACTGGATCTGCAGTTTTCCAAGCTTCAAGGCTCCTCCCAATGATCCTAAATAAATGGAATGTG
AGTGAGGAGTAGAAGAGTCATAAGACCCTGCCTCCATCTCAAAGGAATGTGACTCACACGTCCCGAATGGCTTTGCAGCATCCTGTGCTGGAACTGTGCAGGCAACAGGAGTCATTAATG
AAGGTCTGAAGTCAAGTAGGATTGGTATCTTGGCTCCAGTGCTGAAGACTAGCTGTTGGACCTTAGGCAGATTTTGTTTTAAATCTCTCTAGACCTGTTTCTTCTTATCTGTAAAGTAGC
TATCCTAATGGTGCCTGTGTCTTAAGTTGTGAAGAAATGTAACAACCAATTCAAAGCACTAAGGCTAGCATCCGGCAAACACTCAGGAAATAGTGGCCCTTATTTGCCTCGTGGGTTAGA
GGAGCAACAGCACTGTTCAGGAGAGAATGACCCTAAGAGTCTGGGGTTGGTGGGGTCAAGTTGTTGCTGAGACCCTGCCCTGACCCTCTCTCTCCCTATGGGTTCTTCTGCACCCAAGCT
GACCCAGCCCCATCTCTTGCTTCCCAGCTTTGGAGTGGCAGGGCCGCAATGAACCCTGCAGGCCAGTGCTTGTGCACTTACAGCCGGGACAGATTCGAGTAGTGGATGGCAGGCTCACCG
TGCTCCGGACCATCCAGCTGCGACCCCCACAGCAGGTCAACCTCATCCTGTCCAGCAACCGTGGACGCCGCACCCTGCTGCTCAAGATCCCCAAGGAGTATGACCTGGTATGGCCCAGCT
GGCCTCATCTCAGATGAGGCAGTTAAGTAAAGGGAAAGGAGCAGTAAGCCAGGAGACAGGGGTTTTGGCTTCCAGTTCCCAGATGTGGTACCTGATAGAGAGATGAATTTGAACATGTCC
GCCCTGTTCTAGATCTGCTGGCTGACACCGTCTCCTCTCACTCTGGTGGCAGCTGGCAGCCTTCTTCTTTGGTTATAAGTCCTAGCCATGAGTTCCTGGAAGAACCTGGGTCCTCTTCCC
TATTCTCTTATTTCAGACTCTAGAGGACTTCCTTTTTCTTTTTTCCCCACTAATTAATTAATTAATTAATTAATTAATTAATTAATTAATTAATTAATTAATTAACTTTACATACCCAAT
CACGACTTGGAGGGGAGTTAAACAGGAGGCTGATCATGTGTTTTGACTACCCAGATCACAGTCCACTCCACCCTCTGCCCCAATTCCTTCCCCAACTCCAACCCCTAGTCCCAGCTATTC
TCCAGTATGAAATATGTGTCACTAAAGTACACTTTTCTCTTCTGTAAATGAAGGACAGTTATCTCTTTTGCAAGGCCACACCAATGACCCTTTGTGTGTTCCATGTGAAGCACCTGTCCC
TGAGAGGCTCTGACACGTTTACCTCTGCTATCTTTGAAGGTTCTGTTGTTTAACATGGAGGAGGAACGGCAGGCACTGGTGGAAAACGTCAGGGGAGCTCTGAAGGAAAATGGGCTGAGC
TTCCAGGAGTGGGAACTGAGGGAGCAGGAGCTGATGAGGGCAGCAGTGACCAGGCAACAACGGGGCCACCTCCTGGAGACCTTCTTCAGGCACCTTTTCTCCCAGGTGTGTACATGGGAT
CAGATCTGGTGTGTGCATTTGCATGTGTGGGTGTGCATACGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCGCGTGTGCATCTGTGGTGACATCCTTTCCTATATGAAGCC
ATGGGGATGATCCTTCAAATCTCAAGGCTTGAATGCTCAGCTGAAAAGTCTGTCCTGATTTAGATCAAGTCACCAGGAGTTACTGGAGTCCTAGGCCAGAGGCCAGATCTGAAGGTATGG
GGGTAGGAGTATGTCCCAACAGATTAGGTTCAGCCACTTGCCTCACAAATCAAAGTGGTTACTCAGGGAAGAAATCCAATCAACATAGCCATGTTGGGAAGACAGATGGAATATCTAAAC
ACTGTCTTTGCTGATACTGACACGTACTTCTGGATTATATAGGGAAAGGGCAGAAGAGAAGGCCTAGAGGCATAGTTAGTCAACCTTAGCCAAACCATGGTCTGGTTGGTTAGTATTTCA
GTGTCAGATCCGCAAGTTGGCTCCAGTGACTGTGTTACTTCCCGTTACTTGGGGAAACATTCTGGTTCCCATAAGGTGAATTGTTTTGCTTAGGTGGGCAGCTTCGGTTCCTATCATGGA
GGTACTGCTTCTGTTTAAAGAGTAATGTCATCACGGGGGTGATCTGCCTGCAGGTTCTGCTTGCTGGTCCAAGGTGACTGCAGGTTCATGGCAGCAACTAGAGATTTTCAGGGGTCTGGA
GCAGGATGTAAAGTCTGGTGGTAAAATACTTTTGTTACTCTGTTCTTGAAGCCTTCATCCTTGAAAAGGGATGAGATAGGGCTGGCGAGACGGCTCAGTGGGTAAGAGCACCCAACTGCT
CTTCCAAAGGTCCAGAGTTCAAATCCCAGCAACCACATGGTGGCTCACAACCATCCGTAACAAGATCTGACGCCCTCTTCTGGAGTGTCTGAAGACAGCTACAGTGTACTTACATATAAT
AATAAATAAATCTTAAAAAAAAAAAAGGGATGAGGTAGATTAGGTAAATTTAGGACTGATTACCCGATGACATCAGGGAATTTTTGTTTTGCTTTTTCAAAGGGATTTATTTTTAATTAT
GTCCACATTGGCAAGGGACAAAAGAATGTGGGTGGCAGCAGAGGGCAGAGGTTATCACATCCCTCTGGGACTTGAGTGACAGGCAAGAGGTTGTGAACTTCCTGGGAAACCTAATGAGGG
TGTTGGGAGCTGAACTTGGATCCCCTTGAAGAGAAGTGTGTGCTCTTAACCCCTAGTCTCTTCAGCCCCTAAGCAAGTAACATGCCTTTGTGCCTGAACTGAGCAGGGAATGAAAGCCCA
GAAGAGATACACAAAATAAAGGCACAGAAGCTGAGATTTACTCTGCTCTGAGGAGTCCGTAGGCCCACTTGAGGAGCTAGTGCTCTTCGGCAAAAGCGGTCTCTAAATTCTTCTCATATT
TACTTCGAAGATTTCCCAACCCATGTGAACCCTGTCTCCTGATGTAAGACTCCAGGGAGACAGTGTGCAGGAAGGAAGCAGGGCAAGCCAGTACCGCGGGGCTCCTGAAAATCATACTTC
ATCCTTTCTTCGGGGAGTGCACCATGGAGATGTAATGTCTGCCATATGCATTTCTGAGAACTACCAGGAAGATGTGGAAAATTTTGATAGAGGGGGAAATCCCAAGACTGATGTCCACAT
CTAGTACAAAAATAAAGGTAGCCTGGATAGAACGCTACATTGGAGACAGAAGATTAAATAAGAGCCTGGTGGCACACACCTATAGTTCTACACTGAAAAGGAGAAACACAAGGATTTGGA
GTTCGAGTCCAGCCTGGGCTACTGTCTCAAAACCAACGATGTGCCGACATAGTTTAGTGGTAAAGTACTTGCTGGGATGTGTAAGACTCAGGGTTCTATCCCCAGCATGAGGCTCATGGG
TAGACATGAATCCAGCATGCATGCCATACCCAACACATTAATTAATCTGTTGGGATGGTGGTGATAGTCACACAAAGACTGGTATGGGATGAAGATTATAAAAGCAATGCAGAAACATGT
GATCTAAGATGTTAGAGAAGAAAAGCTTTCAGTCTGGTGCAAGTTCATGATGGAGGCAAGATTGGCAAGGGCTCAAAGGTGGAAGAGTTTTGGCCCAGGAGAAAGGGGTGAGTAGGATTG
AGCACTGAAGAAGAGAGAGAAAGAATGAGTGTCTGAGAAGGAGCAAGGCAATTAGCTGGGAGAGGATTCATACAGGAGACTGTTATCTAATGGGCGTGCGCAATGGACTCTGGGTCAGAC
TTAACTCTTCACCTAATTGAATATGGAGTTTGCCTAAGAAACAAGGGACCCTTGGCTGGTGAGGAGGTCTCCTTGCTTGGGCACAAGTAGAATCTTGGCAACTGCACTCAGGCCAGTTTC
CATCAGGATGAAGGAAAGACCTTGTTCCGGAAGTTTAATAGACTGTCCGCCATCCCCATGGCTGCCCTGTACTTTCCATTTTGAAATCCTTCCCTCTGCAGCCTCTCTTGCTGATTTCCA
TCATAACCTCTGATAAGTGAGGCCGGTGAGGAAATGAACCCCAGACAAACAAAGGATGTGCCCGAGGTTATGGTGCACACAGGTGGCAATGTTGGGACATGAACTCAGGTCTCTTACCTC
CCGCCCCAGGCTCTTCCCACTAAGCACCTTGTCTGAAGTGCAATGCTTGTTTCATGAAAAGACAGTCAGACTTGAACTGAGCAGCTGTTGAGAGGCAGGAAAAACAGGTATTGTGACCTG
AGGCCTACCTCTTTCCCTGTGTCTGTTCTCTTGCTAGAGCAGTCCCTGGGTAAGATGGGGGTGGCCCATAATAAGAATTTTCCTCTCCAAACCCTTGAGATATAAATCAGTCATAAAGGA
TACACATAGTCTCAGGAACCCCAAAGTGGGGTCTTTGGCTTGTCTTGGAAATATCTGGAAGAGAAAGCGGTCAGCAAACAAGGTCTCTCTTCGATTATCTCTACTTTCCCCTTGACCCTT
TCCTCTGCGAGTCTGAACCCACTGTCAAAGCATATCTGGGACCTCTTGGTTCTAATTCTAAATACTCAGGTTAGGTCAAATATACATACTTGGTTCAGTCAGCTAAGCCAGAGGGCCAGG
ACTTTGCAGTTTAAATATAATTACTCACAGACTGCTTATGGTGGTGTGCTGGGCAAATATCTGCCTCAGAAAGTAGCCGCATCAACCTGTAAGTGAAAGATGCCTCCTCTTTCCCCTACC
CCCCACCTCTGGGGCTACCTAAATGCAGGTGTTAGACATCAATCAGGCTGATGCAGGGACTCTGCCTCTGGATTCCTCGACCAAAGTGCGTGAGGCCCTGACCTGTGAGCTGAGCAGAGC
TGAGTTTGCAGACTCCCTAGGCCTCAAGCCCCAGGACATGTTTGTGGAGTCCATGTTTTCTCTAGCCGACAAGGATGGCAATGGCTACCTGTCCTTCCGGGAGTTCCTGGACATCCTGGT
GGTCTTCATGAAAGGTGAGGAAGGAGAAAATAATTGTCCAGACAGAAGTGGGCTACTGATGTTGTATTGGAGATAGAGAGCCTGAGGCTAAGTCTTCAACTACGACCGAGGCCTGGCAGT
CTAGAAAGGGTTTCTAGAGGTTGGGTGGGTCTCTCCTCACAGAACCCTCCTTCTTCCAGGCTCCCCAGAGGAGAAGTCTCGTCTTATGTTCCGAATGTATGACTTTGATGGGAACGGTCT
CATTTCCAAGGATGAGTTCATTAGGATGCTAAGGTTGGTTGTTCCAGCAGGCAGGACAGGGACTGCCAGGGAGAGGGCCATCAATGGGATAGCAGAGGTATAAAGGAGAAGCAGGGGGCA
TCCTCTTTATCTTTGTATCCAGAGCCTTCTAGAATTAATAGGGAGCTTGGGCTTCAGCTAGTTGGGACCCAGTTATGGAGGATCCTGACGTGGATGGCCAGTGCTTGCTTCCAACCCTAG

GTCCTTCATCGAGATCTCCAACAACTGCCTGTCCAAGGCCCAGCTGGCTGAGGTGGTTGAGTCTATGTTCCGGGAGTCTGGCTTCCAGGACAAGGAGGAGCTGACCTGGGAGGACTTCCA
CTTCATGCTGCGGGACCACGACAGTGATCTCCGATTCACACAGCTCTGTGTCAAAGGTGGGGCTGCCTGGTTAGCAGGGCTGATTTATTTGTTGGGTATTATCCCTATATACTTTTAGGA
ACCCACAGAAACACTTCAGAAACACAAGAAGAAAAATCAATACAATAATGAGTACATAATATAGCTAATGCAGATTATATTCTCTTTTATACCCATGCAATTATCAAATAACATTGCTAA
TTTATTTTTACCTGTATGGAGAAAGGAGCCCAAGAAGATGAAAATGCCTTGGGCTTATGAATGTATCCTGGCTGCTGAAGTGGGTGGGAAGAAGACTTTTGTTTGTTTGTTTGTTTGTTT
GTTTGTTTGTTTGTTTGTGACAGAGTCTTGCAATGTGCATGGTGGGTAGTCTGGAACTTGCAATGTAGGCTAGGCTGGCCTTGAACTTGTGGCTGTCCTCCTGTCTCTGCCTCTAAATGC
TGAAGATAACTGATGTGCGCTACTACACCAAGTCTTCAGTAGATGTTGACTGGAACCGCCCTGTTCCTCCTGGCTCCTGGCCAAAGCCACCCCACCCTTGCATCTCTAAGCTTGCAGCAG
GGCAGAAACAATGTTTCTTTGTTACAACTGGATTTGGCCTGACTCAGTTCTCCTCAGCTGGGTCGTGTGGTTCTGGTTTATTTGGGGTTTGGTCCCCCAACTCCCACAGTATCTCCTGGT
TAAATGCTTAGTAAGTGTTTGCTGAATACATCACAGCCCAACTCCTTTGTCCTTCCTGCTCCTTCTTACCCTGGGTCTGACTGGAGGTGGGTGGAGGTCAGGGTCTCAGTGATGAAAGGG
ACAGATATCAAGCAGGGGGGTCTGTGTGTGGCCTGTTCTGAGCTGTCACGACATCTTCGTGATTCTTCTCGGGGCGTGTTGAGACAGAACCTAGTCCTTCCCATATTATGAGACAAGTGG
GGGCTGGCAGCTTTGCTGAGAGACGGGAGCAAGATGAGCATGATGTGGATAAACTTCTGCACGAGGCTTCCTCTGGCCTGAGGGCGAGGGGAGATGTTGAAGAAGAAAGTTGAGTTTGTA
GCTTTTCCTACCAAGCCAAGGCAATGGTGGGCAGAGGCCAGGGAGGAACCTGGAAGTTTCTGCCCTGGGATAACCAGGCAGGGGCTTGAGGATCAAGCCAAAGGTTAACTATGTCTTGAT
TCACTTTTAATCACTTGTTTTCTTCTGATCTTATTTGAGAAAGATTCCACATGACAGAAAAGGCACAAAAATATTACGAACAGCCACTCCCTTTTCATCAGAATCCACTCTTCATCGCTA
TTTCAACACATTTGCTGTTTACTGAAAATTGGAGAGTGGATATCTGAACTTGGTTCTAAACACTTGATGTTAGAGTGAGAGGTACAGATCAGTCGTTAAGAGCTCTTGTAGAGGACCCAG
GTTCAGTTCCCAGTAACCACATGGCAGCTCACAACCATCTGTCACCAAGTTCCAGGGCCTCAGATGTTCTCGTCTGGCCTCCTCTGGCATCAGACATACATATGCTACACATAAATACAT
TGATACAAGCACCCACATACATAAATTTAAAATAAGTAAATCTTTAAGTGCTTGAACTCCACGTAGATCAGTCTATCATAAGCCAAGCCATCTTTGGTGTTGGCTCAGAACTTAAAAGCC
CCTTGGAGGCCCCAGACCTCCTAAGAATTTGCATTTGCAGTTCGACCTTGCTTTGTACAGCTCTGACAGAACAATGAGATGAAGCCTCCAGGGTTTTATTATGAACATTTTCAAACAAAG
AATAGAAAGACTTTTCAGTGACCTCCCTTATCGCTATCTATCACTGATAGGTAAGTGCAGTTCCTATGGGGGCCAAGAGCTGAGGCTGGGATCTCTTTTTAGTGGAGCCTTTCTACAGGC
TTGGGCATAGGAAAAGGGGGACCCTGTGCAGCGAGCCAGGCTCTCCTAGACTCTGGGCACTGAGCTGTCCCCTAACCAAGCTCTGCAACCCAGGTGTGGAAGTGCCGGAAGTGATCAAGA
ACCTCTGCCGGCGAGCCTCCTACATCAGCCAGGAGAAGATCTGGTAAGCTCCCGTCTGCATGTATTGGGTAGTTGTCATTTTGCCAAGAATGGCTGAGGTTGCCCCACCCCCAGCCCCCA
CTACCTATTGTAGCACCTTCATGCAAATAGAAAAGGGCCCCACTTCCTCCAAGTGGACAGACACATCCTTCATCAGGATGAGGAGAAAGCCTGCTGAGTGTCAGCAAAGCTTGCTTCCTG
CTTGGGCCAAATGTCCTTGTAGAGGACACAGTTATCTATGGAGGCCTCAACAGGGACTCATTCTCTCTGTGTCTGCCTATTTGTGGGAATCTTGCTGTCCCATGTGGAGGGTTTTGATCT
TTCCCGGACAAAGTTGGTTTGGAGGCAGAGCAGGAGTCAGATGGTACCTTTTGCCTTTCCTTCCTAGCCCTTCGCCCAGAATGAGCGCCCACTGTGCCCGAAACAACATGAAGACTGCGT
CATCACCACAGAGACTGCAGTGCCCCATGGACACAGACCCTCCTCAAGAGATTCGACGGAGGTTTGGCAAAAAGTATGCCTGTTGTGCCCCTAAAGTCTATGCATCCCTCCAACAATCCA
TTGAGTGGTTCAGGGCTCTCTGCTTTACTGGCAGATAAATACTCTCTGCCCCAGAATGCTTATGTACAGTGAGTCTGGTGCACTGTACTGATGAGTACTGGAATGATAGGAAGGGCAAGG
GAAACTCAAGGCTGTTTTCTCCCTCTGCCTGGGAAGTCGGGAGGGTCTTCAATAGATGCTCTGCCCTAACTAGGTTTTTATTGCTAGGATAAAATCATGACTACAAGTAACTTGGGGAGA
AAGGAGCTTATTTGGCTTACAGGTTACAATATATCAGAGAGAGGTGCCAAGGCCGGAGCTTGAAGCAGAAACCACAAAGGAACACTGGTTACTGGCTCGCTTCCTCCAGCTTGGTCAGCT
ACCTTTCTTACACAGCCTAGGCAACCTGCCTAGGCATGGCACTACCCATGGTGGGCTGGGTCTGCTGACATCAATTAAGGAAAAAAAATATCCCACAAGTATGCCAATCAGATACCAGAC
GTGTCAAGCTGACTACTAAAGCTAACCGTGACAGGCCTCTTGAGCCTTCTAAAGCCTCACTGTGGGTGCCTAGTAGGAACTACAAACAGGGAGAGGAAGAGACTGTCTGTGAATGAATCC
TGGTGTAGATGGAGTGTATCCCCAGAGTTGAAATAACTACTTGGAAGTCAGCCCTCACTTAGACAGTGGGGGGCAAAGCCTTCAGGTCTGAAGCCTGCTGCAAGAGGCTCTGTCCTTCCC
AGGCTGTCCCTGAGGTAGCAGGGTCCCATTGTATTGAGTTTGACAAGCCAAAGGCTCCCTCTCTCCTAGGGTAACTTCATTCCAGCCCTTACTGTTCACTGAGGCACACCGAGAGAAGTT
TCAACGCAGCCGCCGCCACCAAACGGTGCAGCAGTTCAAGCGCTTTATTGAGAATTACAGGCGCCACATTGGCTGTGTGGCGGTGTTTTACACCATCACTGGGGCGCTCTTCCTGGAGAG
AGCCTACTGTGAGTGACATCACATACCGCAAGTCTGGGACAGGGAGTTGGGATCTATTGTGAGTGACACACATCCCGATGTAGGGTTGGGGTTGGGGGGTGGGGGGGGGCGAGCTGCAGT
AAAGGACAACAGCGTCGCCTACAGCCGCACTGTTTCCTCTCCACAGACTATGCATTTGCAGCACACCACAGCGGCATCACCGATACCACCCGTGTAGGCATCATCCTGTCCCGGGGCACG
GCGGCCAGCATCTCCTTTATGTTTTCCTACATCCTGCTCACCATGTGTCGCAACCTCATCACCTTCTTGCGGGAGACCTTCCTCAACCGCTACATTCCCTTCGATGCTGCCGTGGACTTC
CATCGCCTCATCGCCTCCACGGCCATCATCCTCACAGGCAGGGGCTGCTGCTCTGGGCTTCTCTTGGTGCCTTTTGCCCTTGGTGGCTTCCTCTCCTCTCAGACTCCTCCCCACTGTCCT
TTGCACCTAACTTTAATGTCGATAAGGATGGAGTTAGTTGGGCTGTGGGATGAAATGAAGCCCAGGAGCCTACCTTTCTCTGAATGGCTTTTCCTGCATTTTCAAGGGCATCCCTGCCCC
AACTTCTGACAGTCTACCAAGACTCTAGCACAAGGATACAAATGATTGCTTTCCTAGTTCGTATGCTTTAAAACAGATCTGTGAAAGAAACCAAAGGAATGTGCTTCCAGTGGTATAATT
TCAGACTTGTGGCTGTGTTCGTGGGTGGAACGGGGAAGGAGTGGGAGGTTGGTTACAGGTCAGCAGCCCAGCCCCCAAAGGTGCTGTTTCAGTCTGCCCTGTTTGGCACTTGACTGTGTT
GTGCACCCTTGCTGGGCTGTCTCTGGGCTCACCACCTTGTCTGGTCTTTCTTAGTCTTACACAGTGCTGGCCACGTAGTGAATGTGTACCTGTTCTCCATCAGTCCACTCAGTGTCCTCT
CTTGCCTCTTCCCTGGCCTCTTCCACGATGATGGGTAAGTGTGTGTCAGGAGTGAATTTCTTGAAGGGAGAAGAGAAATTTACGTGGCCTAGAGGACAGTGTCACTTTCTGGGATAAAGT
GACAATGATCAAGCTGAGCCATTGGCAGGAGAGACTGGTGACTAGGTTGTGCTGCTCCTCTGGAAACCCTAGGAGAGACGCCAGAGACCTCAGCTCACGACTTTGCTGTGTCTTCTGCAC
AGGTCGGAGTTCCCTCAGAAGTATTACTGGTGGTTCTTCCAGACTGTGCCAGGTGAGAGACCTTCCCTTCTATCAACGTCTAGGCTTCACTCCAAACGCCAGGCTCTGGGTTCTGTCACT
GAACAGCTAAACTTCCTCAACTCTTACAGTGAGCCAGGCTCTGTCCTCGAGGACAGAGGCAGGAAGACTTAGCTTGACTGCATTATAACTCCCTCATCCTTGAGCTAGTTCCTCCCTGGA
AAAGTCTTACTGGCCCTCAGTCTGGTTCAGTTCTCAGGCGGTTGGGGAGTAGGTCCCTTTTCATAATACATAGACCTGTCGTGATGTTTGCCTTGAGAAATGCTGTGTCCCGGCTGCATG
GGAGAAGGACTTGGCTTTTTATCAAACCAGACATAAGTCCCTACCCACACTGTAAGATTTCTTGACAAAGGTCATGGTGGGGGTGGGTGGGTGGAGAAAGCATATTTCTAGCTTCCTACA
ATCACCCATTTCAGAGCTAATAGCTGCGAATCGATTAAGATTTGTCCTAAACCTATTTATATTTAAGTCTGTGTCCTCTTGGGGGTCATGTGTTTTTATGCACTCCTTTCTGTGAAATGC
AGCAGGTTTTTTTTTTTTTTTTTTTGGTAATCCTACTGCTTTGAACTTCAGAGTGCGCTCGCTGACTTCGACGCACTGGGATTTGGTGGATAAGACTGTATTTATGCTCCTCTCTCTACT
CACAAGTTTACAGGCTGTGGTTCAATCCCCTCTTAACCTTCGCTTCTCCACACATCAGGGCTCTAATCTTCCTAATTACTGTCTCTCTCCTCCTTGATCACTGGAGGCTATCCTGGGTTT
CTACACCCCCATCCTGGCTCTAGTATTACCCTCTCTGTACCCTTGACATGGGATCCTCCATGAAAGAGGATGGAGCTTTCTACCAACTCCAGGCTGGACAAAGAACTCTGGCAATCTGCT
AGGTTAGTATGGTCCCATGCACAGATTGGTTCATAGTTCATGTCAAGTCCTATGATAATCAGTGGTTGGTGTAGTTTTGACACCATGGGGACAGAGCATGATATTCCCCATGTCTCATTT
AGAGGCTTCTGTGCATTCAATTCATCCAGCACACATTTATACAAAGCCTGCAGTGTGCCAGGCCTGGCAACAGGCAGGAGGATCAGTGGTGAGACAGCCTAGTGTGGTCCTTTTTCTTGA
GGACCTGAGGGTCATGAAAAGGGGTGACACTTAAAAAATGTGATGACACAGGTGGAAAGGATTACAGCTATAGACGATGAAGTGGCTCTGTTGAATCAAACGGTACCTATGATCTGGGCA
TACTTAAGTTCAAGACCACTTTGTCACTCCTCCAGTTCAGACAGGAGTAGAGAGGGACATGGCTGAATACCCCAGGACACACCCTCCACACTGCACTGTCCCTCAGTCTTCTGCCTCCTG
TCCTCTTCACAGGTCTCACTGGGGTCCTCCTGCTCCTGGCCCTGGCCATCATGTACGTCTTCGCCTCCCACCACTTCCGCCGCCGCAGTTTCCGGGGCTTCTGGCTGACCCATCACCTCT
ACATTTTTCTCTACATTCTGGTGAGGGGTTCTGGCCGTGGTCCAGGCCTGTGGGGTATATGAAAGACATTCCTTGGGAGGCCATGGAAGCTGGGACATTGGTTTTCCATCCCCTAAGTTA
TTTCAAGTATCCATTTCTCCACGTCCCTCTACAAAGATGGAAATTATAGAGTGGTGCTCTCCAGTAGGTTGACCCCATTATGCGGCTCTTGGAAGATTCCTTCCTTTCCATGGGCTTTTT
TTTTTTTCTCAGTAGTAGCTCTGCCAGGCTCATCCACATTCCTCACAGACTTCCCCACACCATTTCTTTCCAGTTCTTCTCTACCTTTGAGTGGCTGGTTTTTGGTTCCATAGTGGACTT
CTTGCACCTTAAGGAAGAATTATTCTTTTGGAGGAAGTTTAAAGGGTTCTTTTCTGTTCTGATCTCTTCTGAGACTGCATTAGCCGCATCATCTGGCCAAACAACACCTGTAAAGTTAAT
AAGGTCACTCAAACCACCAGCCAGCCAGATTGCTGATAAGATATACTTTAAGACTCCACCTTGTTAGGTTTCAGATGGAACAAATGGTTCAAGAGGACGCCGAGATGGATTACTGGAGGA
TAAGGAGCTTATAAGTGTTATCAACACCATGGACAGGCAGACAGACAGAGGTGTAGATGGTCTGGGATCCAAGGAGAGAGTTCAGGTCCAGATACCAGAGACAGAATGGCTTGGGTCTTT
GAAGACAGTCAGAAGCTAGGTGGCAGAGGAAGGGATCTCTTAGACCTTTTGAGGATGAAGGAGGTTTACACCAAGAACCTGCAGCCAGGAGGAGGCAGAGAGGGGAGCAGAGAACAGATG
TGGCATTCCTTTGATGTAGACTCACTTCCCCAGGAGATGCCATGACACTGGCCTGTCAGCTAACTCAGGACTCAGAGACAATGCCTGACAGTATCAGTGAGAGCCGGTCCAAGCAGAGGC
TGGGTTCTACTGTTGCTGTTCTTACACTGTCTCCTTCTCAACCCAGGGTCTTTTTTCCTCATGTTCCCTCCCTTCTTCTGATCCTTTCACTGTCTTGTCATCAGCTGATTCACCTCAACT
CCCGAGCCAACTCTGACCTGGCTCCCTGTGCTATTACACAGATTGCCCACCTTCCTCAGGTACACAGTACTCCGCAGAGGGCACTGTACTCAGGTCTGAAGGCCTTCACTTTTTCTACCT
GATGACTGATGGCTTGGCTGCTAGCATTCATAGAGCCTAAGCCCCCTTGACTGGCATTTTTATTTCCTAATAGAGCAGCATACAGGGATCTCCTTTGTTCTGAGATGAAGAATAAGAATG
TACCACTGCCTGGGTGTGGCTTGATCCTGTTACCCCACCCCTCCTCCTCCCAGATGCAGCTCTGTCTTCACTAATAGCTGGGACACAGACACACAGACACACAGACACACACACACACAA
TTTGCCTGTGGCTCAGCACATCCTGATTCTGAAATAACTATCTGGCTTGGCTTAGGATATTTCCTAGAACTGCTGATGTCTATTTCCAAAGAACCTCTCCCTCCTCTGGGAGCTGTGGCT
AACTAATTTCCTCCCTTCCCACTAATTTCCTACCTATTCAAAAATGTGTGGATCCCTAGCCTTCTGCCCTTTGCTTCTGCTACGAAAATGCTGTTTCTTGTTTCCTGGTGATAAAACTAG
AGGGAAGATCCTGTAGAGTGGCTAGCTTGATACCCTAAGTCCAAGACTACTTCCTGATTCATTGCTATTGTAGACAACACTGGATTGTTGGGCAGCTCTAGCCTGGCAGATTGGGAACCT
TTTATATGTGGGGAGGGAGATCGGGAACATAGCAACTATCTTATCACTTATCACAGGGGGTGGAGGAAGGCACTTGGCTCTGGGCAGAAAGGAAAGTTATAAGTAAAAGACCCCAGCATA
GAGCAGACCTTGAGAAAGAATGTCTAAGCTGGCAACTCAGAAACTGAACTGCCCCACCATGAAGGAGAGCTTTAAAAATTTGGAACTCTTTACTGGGGAAGGAATTCCTGAACAAGAGGC
CTGATTTCAATGAAACAGATAGCAACCAAAGGTCTCTTCTGTCTTAGCTCTGAGGGAGGCCCAACAGGTGGCAACACTAAACCCCACCTTTAGGAATTTAGGATTTGCTACAGAGATCAG
TGCCACATGCACACCAAATAGAAGGAATTGCTGAGCAGAATGTCCCAACAGTAAGGCCTAGAAAGTCAAGGAGGAAAGTTTTACTTACACTGAACTAGTCAGGGGCGACTTTGAGAGAAA
ATGGGACTCAGGCCACAGCTTTAGAAGAGAGAGCGAAACAGTGACAAGGCTGAGTGGGAACTGAAGAGCAATCCAGGTAGAAGGGCATGCACACCGATATAGGGTGGGAAACGTGACAGA
CTATCCAGGGACAAAGGAGACAGGCCTGGGTAGCTGGCGACATGTGGAGGTGGCATATAAGGCAGAATGGTTATGGCTCATTAGAGCCCATGGGCATGGTGGAGCACAGAAAGACAAGAG
CAATGGGTAAGGAAACTAAGCTTGGGCCACACCCATGACTGGGGATGACAGTGGAATGGTGGCTGGGAAGGCTGAGGCAGAACCAGAAGAGCACTGTTGCTGAAATAGCTATGAGACACG
GAGGTGAGGATGGGTCACTAGTGTCACAGGCTACAGAGAGGAAGCAGGCATGACCTTAAAGAAAACCTTGCAGTAGGGGGCTGATAGCACATGCCTACAGTCCCAGCTACTTGGGAGCCT
GAAGTAGTACTGTAAGTTCACAGCCTGCCCGGTCTACAGAGTGAGTTCAAGGTTAGCCTAATTGAATCATTAAGGCTTCCTCAAAACAAAAAAGTAAGAAAAGAGCTTGGATGTAGCTCT
GTGGTGAACACTAATCTAGCAAGTGTTTTGTTCTCTAGGCTTAAATCCTAGAGAACAAAAGAGAGGAAGGGAGAGAATCTTGTGTAGAGGTGGTTATAGTCTGTCAGGCTCTTTCATCGA
AAAGGTAGACTAGTTAGGTGTTCTTAGCCACCAAAAGGTGGGATAAACAGGACGTCCTCTTCCTGGCCATTACTGAGTACTAAGTGGGTACCCAGCAGGCACTACGAAGAACCAAAATGA
TGCTAGCACAGTCCCTGCCTCCTCAGACCATTCAGGACAATGATATGTATGGGAATGAGCAAAGGCTGATTATGGATGATGGCAGATTAAGTTAACAAGGAGATGTGATGTGACTGACAC
AAGGCCGAAGAGGCTCCATTTCTGCTGAAACTTGGGGAGGGGGTGGAAACTGCCATGGCAAGCACTAGGAGTAGGAAGCCCAGGCTTCCCCTTAGCCCTGTAAGTGCAAAGATTCAGAAC
CCAAAAGAATTGTATTTGAGGAACAGGGAGGAAGAACCAGCCAGAAGGGTTCTAGAGGCCATAGTGCTGCAAGGCCAGAGAGTATAATGGAAGGTTCACTAAGGCTCTTTAGACAGAAGG
CATGATGAAAAAGGACTTCAAAGGGTCACATTGGCCAGGTGTGTTGACACAGGCCTGTAAATCCTGCACTCAGAAGGCTGAGGCAGGAGGATCACCACAAGCTCAAGGCCAGCATGGGCT
ACATCTGAGATCAGCCCTTCCCCCTCCCCAACACACTTGTGAAATACACACACTAGGTATCTTACAGAGTCCAGGTGGGAGTCAACTTGGTTATGTCTAGGATGCTAGTATTCCTTTGCC
ATGCTTTGGAGGATGGTGGTGGCAATGGTTGTTTTAGAGCCTAGATGGTGAGGTGGTGAATAGATGCCCTTGTGGAGAAGTTCATAGGGTCTAAGGACAAAGCTGGCATCACAGTCTGTT
GTGTGTACCTCTCGTCTGAGCCATATTCTTTGGTTTGTGCAGCTCATCATACATGGCAGCTTTGCTCTGATCCAGATGCCCCGGTTCCACATCTTCTTCCTGGTCCCTGCAATTATTTAT
GTGGGGGACAAGCTGGTGAGCCTGAGCCGGAAGAAGGTGGAGATCAGCGTGGTGAAGGCTGAGCTGCTGCCATCAGGTACAAGCCTGGAGGTTGTGAGAGAACCAGCTTGGCTACTAAGG
CAACTGACCAGGCACAAACAGTGTCTGGACCACTCAAGTCTACTGGCCTTGCCCAGTGGGGGCAGAAGGGGCCTAGAGCCATTGGAAGGAGTAATTCAATGAGAAACGTTCTTTGCTAGA
TTAGGCCCTGCTTAAGACAGAGAGTGGAGGAGACTGGGCCAGGCTTCCTCTTGCCCTGTGCATCCCCGGCTCCTCCTCAAGGCAAGGCTCTATAAAGGAATGTCTACTTGTTATCAGAGC
TGAGGTTGGAGGAACTTCTGGAGACCATACTGTTGCTGGGTCCAAGGCAACAGTTTCTTGCATCATCCCTTCCTAGGAGTGACCCACCTGCGGTTCCAGAGGCCTCAGGGCTTTGAGTAT
AAGTCAGGGCAGTGGGTTCGGATTGCGTGCCTGGCTCTGGGAACCACCGAGTATCACCCTTTCACACTGACTTCTGCACCCCACGAGGACACACTCAGCCTGCACATCCGGGCGGCTGGA
CCCTGGACCACTCGCCTCAGGGAAATCTACTCACCCCCAACGGGTGACACCTGTGCCAGATACCCAAAGGTGCCCTGACTTCATAAATCTATTCACTCTTCAATTCCCCCAGCATCTCAG
GCTCCCCATTGTACCCTCTTCCACAATCCAGAGACTTGCTGTTCCAGAAAAGACACAGATCCAACCCCACCCTGTATTTTTCCTGATGTCATATAACTCCCTACCCCTGCCTACTGTTTC
CACTTCTGGCTTCAGAATGATGACCAAGCTGAATTTAAAAACCACTGCACTCCCTACAGCTGTACCTCGATGGACCGTTTGGAGAGGGCCACCAGGAGTGGCACAAGTTTGAGGTGTCAG
TGCTGGTAGGAGGGGGCATTGGAGTCACTCCCTTTGCCTCCATCCTCAAAGACCTGGTTTTCAAGTCATCAGTCAGCTGCCAAGTGTTCTGTAAGAAGGTGAGTTACCAACCCCCATTTG
CCTAACAATGACTGCACCTCCTGCTTCCATCCTTGTCTCTGATATTTGGTCAAAGGCTAGTCAGTCTGAAACCTGGAGAGGGGCAGTGTGTTGGAAAGATGCCAGGGTGTTCTGACGGGC
AGAGTTGGTATGCTGATGTCCGTAAGGCCCCCACCCAGTTTCCAAGAGCTCCTTCATAGGAGTGCCCATATAGGAGTTACTTGTGGGAGTCTCTCCAGGAAAGGCTCAAGGAAGGTAAAA
CAAAACAAGCAAGCAATGAAACTACATTCCCTCATCCAGAAGAGGCCAGCCCTTGGAGCACTGGCTGGGAGAGGGAAGGGTGCCTTTCGGGTGGGGCACAAGTAAAACTGGCTTATGTCT
CAGGATCCGGGGGAGGTACCAAGGTAGGACTTGCAGGTAGGTTGGCCCTAGCAACATGGCCAAGGCTTCAGGCCCCCTTTTCTGTAATTCCGACCCAGTGGCAGGTCCTTGCTTGTCTCT
CTGGGCCTGGCAGGTGAATCAGGTGTGCTGGAATGTGGCAGGCAGAGGCCCAGCCTATGCGTTGCCTGCACTCAGAGGGTGCCAACTCTTCTTCTGTTCCTTCACTTGCAGTACCTGGCT
TATCCTCTTGAAAGCTTGAGTTGGCTCCTGCCAGGGAGGCCTCCTTTCTTTTTTTAAATCACATTTCAGGCAGCTAAAGATCCCTAGGGTGGCAGCTCTATGAAATGCCTTTCAGCTCAA
AAGTTCTGCCTCTAGGCAGCTGCTCACACTAGAATGGGCTTGGCTTGAGGAAGCTGCCTTGGACCTGACAGACGTTCAGATCAGTGGTGGAAGGCTCTTTGGTGAGATCGCTTCTCACTC
ACACCACTCTGTCCAAGGGCAAAATACATCTCTGTATTGAGGCTGGCCCTACTTCCTGTACATTCTATTTCCTAGGTGGTCTAGGGATAGGAACAGACTAGCTGAGGTCAGAATTCCATG
TTGAGATCCAGGATCTATAGGGAAGCCAAGCTGAGCTGGCCCTGAGCCCCAGTGTGTGCCCTCAGATCTACTTCATCTGGGTGACAAGGACTCAGAGGCAGTTTGAGTGGCTGGCTGACA
TCATCCGGGAGGTGGAGGAGAATGACCGCCAGGACCTGGTGTCTGTGCACATCTATATTACTCAGCTGGCTGAGAAGTTCGACCTCAGGACCACCATGCTGGTAGGTCAGGGCAAGCCAG
GCATGGCAGGAGGGCCACTCCCAGGGCCAAGGGTTGTTCCTAGCAATGGCCTTCCTCCCCCATTTCATTTGCCAGTACATCTGTGAGCGGCACTTCCAGAAGGTGCTGAACAGGAGTCTG
TTCACGGGCCTGCGCTCCATCACCCACTTTGGTCGCCCTCCCTTTGAGCCCTTTTTCAACTCTCTGCAGGAAGTCCACCCCCAAGTAAGTCTACTTCATATCTTAGTTCTCGGCTCCTTT
GATCACCCGAGGACTGAGCAAAGCTCTCAATCCTAGTCTATCAAGGAAACAACTGGTTACTGCTGAGAAGTCATCTCTTGGGAGACTGGTATGTTACAGACTGGAGAAACATAGATGGAG
GGCCACCCTAAGGTAGGAAGGAAGGAAAGACGGATGAAGGGAACAGAGATCTGCCAACTCTGAAGTCTAAGTTCATCCACCAAAACAGAAGAGCTCAGTAATAGAAATATTCCTTACTAT
ACAGTCAGGGCTATACTCACCATTAATACTAAGCCAGCTCTCCCCGTGGATGTGGAACTAGTTTTCGCCATGAACAGTGAGTGGGCTGGCTGCAGATAACTTATACACCAGGCTGTCCCT
CAATTTGAACATTGACTCAGTTGGTCCTTTTACACTGACCTAGCACTTACAAAATTGAGCTAGACTTACAGTGAGCCAGCCCTCACCATACACGGTATAAAATAAACCTTGAGTGTGAAC
ACTGGATGGTCTTTAATAGGACCATAAAGCTAACCTGCACCAGGAACATGAACCTGGCTACTGTTTTGAATACTGATCCAGCTCTACCAGTAAATATGTTCATCTTTGGCTCTTCCTCCT
TCAACAGGTCCGAAAGATTGGAGTATTTAGCTGTGGTCCCCCTGGCATGACCAAGAATGTGGAGAAGGCTTGTCAGCTCATCAACAGGCAGGACAGGACTCATTTTTCTCACCATTATGA
GAACTTCTAG

Retrieve as FASTA  
CDS►
Send to BLAST
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
ATGGGGTTCCACTTAGCTCTGGCCTGGATTCTCCTGGTTGGGACACTGGCTTCTTTGGGAGCTCAGAACTCCATTTCTTGGGAGGTACAGCGATTTGATGGATGGTATAACAACCTCATG
GAGCACAGATGGGGCAGCAAAGGCTCTCGGCTGCAGCGCCTTGTTCCAGCCAGCTATGCAGATGGTGTCTACCAGCCCCTGAAAGAACCCTACCTGCCTAACCCCCGACACCTTAGTAAC
AGGGTCATGAGAGGTTCTGCAGGGCAGCCATCTCTTCGGAACCGTACAGTCCTGGGTGTCTTCTTTGGCTACCACGTGCTCTCAGACCTGGTGAGTGTGGAAACACCAGGCTGCCCCGCA
GAGTTCCTCAACATTTACATCCCGCATGGGGACCCGGTGTTCGACCCTGACAAGCGCGGGAACGTGGTGCTGCCCTTTCAAAGGAGCCGCTGGGACCGCAACACTGGACAGAGCCCCAGC
AACCCCCGGGACCAGAGCAACCAGGTGACCGGCTGGCTAGATGGCAGCGCCATCTATGGCTCCTCTCATTCCTGGAGTGACACTCTGAGGAGCTTCTCTGGAGGACAGCTGGCTTCTGGG
CCTGACCCTGCTTTCCCATCGGACTCCCAGAGCTCTCTGCTCATGTGGATGGCGCCGGACCCCTCCACAGGGCAGGGAGGGCCACGGGGGGTGTATGCCTTCGGGGCCCAGCGCGGGAAC
AGGGAGCCCTTTCTGCAGGCTCTGGGCTTGTTGTGGTTTCGCTACCACAACCTGTGTGCCAGGAAGCTGGCGCAGGAGCACCCGCACTGGGGGGATGAGGAACTGTTCCAGCATGCTCGC
AAGAGGGTCATTGCCACCTACCAGAACATTGCGATGTATGAGTGGCTGCCCAGCTTCCTGAAGCAAACTCCTCCGGAGTATCCAGGATACCGTCCATTTCTGGACCCCAGTATCTCCCCA
GAGTTCGTTGTGGCCTCTGAGCAGTTCCTCTCTACCATGGTGCCCTCTGGGGTCTACATGAGGAATGCCAGTTGTCATTTCCAGGGGATTCCCAGTCATAACTCAAGTGTCTCTGGAGCT
CTCCGGGTCTGCAACAGCTACTGGAGTCGAGAGCACCCCAAGCTACAAAGGGCTGAAGATGTGGATGCACTGCTGCTGGGCATGGCCTCCCAGATTGCTGAGAGAGAGGACCACGTGGTG
GTTGAGGACATGCAAGATTTCTGGCCTGGGCCACTGAAGTTTTCCCGTACAGACTACCTGGCCAGCTGCCTGCAGAGGGGCCGGGATCTAGGCCTGCCTTCTTACACCAAAGCCAGGGAG
GCACTGGGCCTGTCTCCCATTTCCCACTGGCAGGACATCAACCCTGCACTCTCCAGGAGCAATGGCACTGTGCTGGAGGCCACAGCTGCCCTGTACAATCAGGACCTGTCTCGGCTGGAG
CTACTCCCAGGGGGGCTTCTGGAGAGCCATGGAGACCCTGGACCCCTTTTCAGCACTATTGTCCTTGACCAGTTTGTCAGGCTACGAGATGGTGACCGTTACTGGTTTGAAAACACCAGG
AACGGATTGTTCTCTAAGGAAGAGATCGCAGAGATCCGAAACACTTCCCTACGGGACATTCTAGTGGCTGTCACCAATGTGGACCCCAGTGCCCTACAGCCCAATGTCTTCTTTTGGCTT
GCAGGAGACCCCTGTCCACAGCCAAGTCAGCTCAGCGCCAAGGGCCTGCCAGCCTGTGCCCCCCTCTTCATTCGGGACTATTTCGAGGGGAGTGGATTTGGCTTCGGACTCACCATTGGG
ACCCTTTGCTGTTTCCCCTTAGTCAGCCTCCTTAGTGCCTGGATTGTTGCCCGGCTTCGAAAGAGGAATTTCAAGAGGCTCCAGAGACAAGACCGCCAGAGCATCATGTCGGAGAAGCTT
GTAGGGGGAGTGGAAGCTTTGGAGTGGCAGGGCCGCAATGAACCCTGCAGGCCAGTGCTTGTGCACTTACAGCCGGGACAGATTCGAGTAGTGGATGGCAGGCTCACCGTGCTCCGGACC
ATCCAGCTGCGACCCCCACAGCAGGTCAACCTCATCCTGTCCAGCAACCGTGGACGCCGCACCCTGCTGCTCAAGATCCCCAAGGAGTATGACCTGGTTCTGTTGTTTAACATGGAGGAG
GAACGGCAGGCACTGGTGGAAAACGTCAGGGGAGCTCTGAAGGAAAATGGGCTGAGCTTCCAGGAGTGGGAACTGAGGGAGCAGGAGCTGATGAGGGCAGCAGTGACCAGGCAACAACGG
GGCCACCTCCTGGAGACCTTCTTCAGGCACCTTTTCTCCCAGGTGTTAGACATCAATCAGGCTGATGCAGGGACTCTGCCTCTGGATTCCTCGACCAAAGTGCGTGAGGCCCTGACCTGT
GAGCTGAGCAGAGCTGAGTTTGCAGACTCCCTAGGCCTCAAGCCCCAGGACATGTTTGTGGAGTCCATGTTTTCTCTAGCCGACAAGGATGGCAATGGCTACCTGTCCTTCCGGGAGTTC
CTGGACATCCTGGTGGTCTTCATGAAAGGCTCCCCAGAGGAGAAGTCTCGTCTTATGTTCCGAATGTATGACTTTGATGGGAACGGTCTCATTTCCAAGGATGAGTTCATTAGGATGCTA
AGGTCCTTCATCGAGATCTCCAACAACTGCCTGTCCAAGGCCCAGCTGGCTGAGGTGGTTGAGTCTATGTTCCGGGAGTCTGGCTTCCAGGACAAGGAGGAGCTGACCTGGGAGGACTTC
CACTTCATGCTGCGGGACCACGACAGTGATCTCCGATTCACACAGCTCTGTGTCAAAGGTGTGGAAGTGCCGGAAGTGATCAAGAACCTCTGCCGGCGAGCCTCCTACATCAGCCAGGAG
AAGATCTGCCCTTCGCCCAGAATGAGCGCCCACTGTGCCCGAAACAACATGAAGACTGCGTCATCACCACAGAGACTGCAGTGCCCCATGGACACAGACCCTCCTCAAGAGATTCGACGG
AGGTTTGGCAAAAAGGTAACTTCATTCCAGCCCTTACTGTTCACTGAGGCACACCGAGAGAAGTTTCAACGCAGCCGCCGCCACCAAACGGTGCAGCAGTTCAAGCGCTTTATTGAGAAT
TACAGGCGCCACATTGGCTGTGTGGCGGTGTTTTACACCATCACTGGGGCGCTCTTCCTGGAGAGAGCCTACTACTATGCATTTGCAGCACACCACAGCGGCATCACCGATACCACCCGT
GTAGGCATCATCCTGTCCCGGGGCACGGCGGCCAGCATCTCCTTTATGTTTTCCTACATCCTGCTCACCATGTGTCGCAACCTCATCACCTTCTTGCGGGAGACCTTCCTCAACCGCTAC
ATTCCCTTCGATGCTGCCGTGGACTTCCATCGCCTCATCGCCTCCACGGCCATCATCCTCACAGTCTTACACAGTGCTGGCCACGTAGTGAATGTGTACCTGTTCTCCATCAGTCCACTC
AGTGTCCTCTCTTGCCTCTTCCCTGGCCTCTTCCACGATGATGGGTCGGAGTTCCCTCAGAAGTATTACTGGTGGTTCTTCCAGACTGTGCCAGGTCTCACTGGGGTCCTCCTGCTCCTG
GCCCTGGCCATCATGTACGTCTTCGCCTCCCACCACTTCCGCCGCCGCAGTTTCCGGGGCTTCTGGCTGACCCATCACCTCTACATTTTTCTCTACATTCTGCTCATCATACATGGCAGC
TTTGCTCTGATCCAGATGCCCCGGTTCCACATCTTCTTCCTGGTCCCTGCAATTATTTATGTGGGGGACAAGCTGGTGAGCCTGAGCCGGAAGAAGGTGGAGATCAGCGTGGTGAAGGCT
GAGCTGCTGCCATCAGGAGTGACCCACCTGCGGTTCCAGAGGCCTCAGGGCTTTGAGTATAAGTCAGGGCAGTGGGTTCGGATTGCGTGCCTGGCTCTGGGAACCACCGAGTATCACCCT
TTCACACTGACTTCTGCACCCCACGAGGACACACTCAGCCTGCACATCCGGGCGGCTGGACCCTGGACCACTCGCCTCAGGGAAATCTACTCACCCCCAACGGGTGACACCTGTGCCAGA
TACCCAAAGCTGTACCTCGATGGACCGTTTGGAGAGGGCCACCAGGAGTGGCACAAGTTTGAGGTGTCAGTGCTGGTAGGAGGGGGCATTGGAGTCACTCCCTTTGCCTCCATCCTCAAA
GACCTGGTTTTCAAGTCATCAGTCAGCTGCCAAGTGTTCTGTAAGAAGATCTACTTCATCTGGGTGACAAGGACTCAGAGGCAGTTTGAGTGGCTGGCTGACATCATCCGGGAGGTGGAG
GAGAATGACCGCCAGGACCTGGTGTCTGTGCACATCTATATTACTCAGCTGGCTGAGAAGTTCGACCTCAGGACCACCATGCTGTACATCTGTGAGCGGCACTTCCAGAAGGTGCTGAAC
AGGAGTCTGTTCACGGGCCTGCGCTCCATCACCCACTTTGGTCGCCCTCCCTTTGAGCCCTTTTTCAACTCTCTGCAGGAAGTCCACCCCCAAGTCCGAAAGATTGGAGTATTTAGCTGT
GGTCCCCCTGGCATGACCAAGAATGTGGAGAAGGCTTGTCAGCTCATCAACAGGCAGGACAGGACTCATTTTTCTCACCATTATGAGAACTTCTAG

Retrieve as FASTA