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Entry information : HsGPx04-B
Entry ID 3632
Creation 2006-08-23 (Christophe Dunand)
Last sequence changes 2016-06-28 (Harold Duruflé)
Sequence status complete
Reviewer Not yet reviewed
Last annotation changes 2016-06-28 (Harold Duruflé)
Peroxidase information: HsGPx04-B
Name HsGPx04-B
Class Animal glutathione peroxidase    [Orthogroup: Gpx1002]
Taxonomy Eukaryota Metazoa Chordata Mammalia Hominidae Homo
Organism Homo sapiens (human)    [TaxId: 9606 ]
Cellular localisation N/D
Tissue type N/D
Inducer N/D
Repressor N/D
Best BLASTp hits
Perox score E-value HsGPx04-B
start..stop		 S start..stop
PtroGPx04 353 5.15e-126 1..168 1..168
PpyGPx04-A 353 5.15e-126 1..168 1..168
HsGPx04-A 353 5.15e-126 1..168 1..168
MnemGPx04 352 1.63e-125 1..168 1..168
Gene structure Fichier Exons►
ExonStart..EndSize ExonStart..EndSize ExonStart..EndSize ExonStart..EndSize
N° 1 1..84 82 N° 2 1143..1237 93 N° 3 1323..1467 143 N° 4 1615..1766 150
N° 5 2199..2223 23 N° 6 2335..2416 80 N° 7 2497..2597 99  
join(1..84,1143..1237,1323..1467,1615..1766,2199..2223,2335..2416,2497..2597)


exon

Literature and cross-references HsGPx04-B
Literature Oh,J.H., Yang,J.O., Hahn,Y., Kim,M.R., Byun,S.S., Jeon,Y.J., Kim,J.M., Song,K.S., Noh,S.M., Kim,S., Yoo,H.S., Kim,Y.S. and Kim,N.S. Transcriptome analysis of human gastric cancer. Mamm. Genome 16 (12), 942-954 (2005)
Protein ref. UniProtKB:   P36969-2
DNA ref. GenBank:   NC_000019.9 (1104043..1106636)
mRNA ref. GenBank:   NM_001039847
Cluster/Prediction ref. Genebank:   2879
Protein sequence: HsGPx04-B
Sequence Properties
first value : protein
second value (mature protein)
Length (aa):   %s   227 (202)
PWM (Da):   %s   24793.51 (22304.1)  
PI (pH):   %s   9.39 (9.11) Peptide Signal:   %s   cut: 26 range:26-227
Sequence
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.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
MSLGRLCRLLKPALLCGALAAPGLAGTMCASRDDWRCARSMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRILAFPCNQFGKQEPGSNEEIKEFA
AGYNVKFDMFSKICVNGDDAHPLWKWMKIQPKGKGILGNAIKWNFTKFGHRLSTVPHRQERLRGEALRTHGGAPGDREGPAPLFLAPQVCGPARAPAHALGAFHRHS

Retrieve as FASTA  
Remarks Complete sequence from genomic (chromo 19, 6 introns). This variant (2) uses a frame-shifting alternate splice site in the 3' coding region, compared to variant 1. The encoded isoform (B) is longer and has a distinct C-terminus, compared to isoform A
Promoter►
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.........1 .........2 .........3 .........4 .........5 .........6 .........7 .........8 .........9 .........0 .........1 .........2
CTGCCTCTGC CACCAAACCA TCCATGACGC CTCTGTGCTG CATCTGGCAG GCCTGAGTCG GGGGCAGTGG CGGGGGCAGG CTCATAGCAC CCCCCAAGTC AACCCGGCCC TGAGTCTGTC  TCTGAAGAAA TACTCAGTGC AGGGTCAGAA AAGGTTAAGA CCTTGAGGAC AACATACAAA TCCCAAGCAC CTAGGCGGGG TAGAGTGGCT CACACCTGTA ATCCCAGCAC TTTGGGAGGC  CGAGGCAGGC GGATCACCTG AGGTCGGGAG TTCGAGACCA GCCTGACCAA CATGGTGAAA GCCCGTATCT ACTAAAAACA CAAAAATTAG CTGGGCGTGG TAGCACATGC CTGTAATCCC  AGCTACTCAG GAGACTGAGG CAGGAGAATC ACTTGAACCC GGAAAGCGGA GGTTGCAGTG AGCTGCGATG GAGCCACTGC ACTCCAGCCT GGGTGACAGA CCAAGACTCC TCAAAAAAAA  AAAAAAAAAT CCAAACCCCT GCCTGTACAG GGGTCAAAGT CCAATCACGG TGACTCAGTT CCCAAGTATG AGATGAGTGT TTCTGTTGCC ACATGTCCAA GCCACGAAGT GAAAAACAGA  GTTGGAAGCC AAGATGTGGG GCAGTATGGG CTCGGGTGTG CCCATACCTT GTAATGTTAG AAGTGTAAGA AAACCCTCCA GACTTGTGTT TATTTTCTGA GCACATACCG CGCGTCCCTG  CGTGGGCAGC TGCCCCTGGG GGTGGGAGCC CAGGAAACTC CAGGTTCTCA GTTAAGTGGT AACTGTCTTG ATGACTCTCA GGTCTCAGTG CCCACATTAT ACAAGCGGCT CAGCAACCAG  ACCCAGGATG GGGAGTCACT GACCCCCTGC GCCCATGGCA GGGGTGAGGG TAGGGACACC CCCATAAGAT GGAGCTGTGA TGAGAAGCAA ACCCAACTCA GTTTGGTTTC ATTTACATTA  AAAAGGCAAA TCCCTTGGCC GGATGCGGTG GCTCACACCT GTAATCCCAG CACTCTGGGA GGCCTAGGCG GGCAGATCAC CTGAGGTCAG GAGTTCGAGA TCAGCCTGGC CAACATGGTG  AAACCCCGTC TCTACTAAAA ATACAAAAAA ATTAGCTGGG TGTGGTGGCT CGCTCGTGTA ATCCCAGCTA CTCAGGAGGC TGAGTCAGGA GAATCGCTTG AACCCGGGGG CTGGGTGGAG  GTTGCAGTGA GCTGAGATAG CGCCACTGCA CTCCAGCCTG GGCAAAAGAG CAAAAAAACT GTGTCTCGGA AAAAAAAAAA AAAAAAAGGC AAATCCCGGC CGAGCCTTTG GCTCACGCAT  GTGATCCCAG CACTTTTGGG AAGCTGAGGC TGGAGGATCA CTTGAGGTCA GAAGTTTGAG ACCAGCCTAG GCAACATAGC GAGACCCCCA TGTCTACAAA ACAATAATTA GCCAGGAATG  GTGGATGAGC CTGTTGTCCC AGCTACTCGG GAAGCAGAGA CGGGAGGTTC GCTTGAGCCT GGGAGGTCGA GGCTGCAGTG TGCCCTGATC GTGCCACTGC ACGTTAGCCT GGGCAACACA  GCAAGACCCC GTGTCTTAAA AAAAAAAAGG TAAATAAGAG TTGGGGACAC TTTTCTGCGA GTTGGAGAAA CCAAACCCCC TCGACGAGTC TTAAGTAGTA TTCTCAGGTT GTCTGGCCTG  CGGCCGCGCT GCTGTCAACC AGCCGGATAA CTGCGCTGCC TCCCGACGCG CCGCCAGCCA GGCCACGGCC TCCTAGACAC AAGCGAGCAT GCGCAGTCGC CAACAACAAG TCCGCACGTC  CGGTCCCGCC CCCCCTTCCC CGCCTTCTTC CCACTCCGGC CTCCCATTGG CTGACGTCGG CGCGAGCGCT CAACACCGAC GCGTCTGACC AATGAGCGCT CTGGAGGGCG TGGCCGTGGG 
AAAGGAGGCG CGGAAAGCCG ACGCGCGTCC ATTGGTCGGC TGGACGAGGG GAGGAGCCGC TGGCTCCCAG CCCCGCCGCG 

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Terminator +►
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Send to cis Analysis
.........1 .........2 .........3 .........4 .........5 .........6 .........7 .........8 .........9 .........0 .........1 .........2
CGGCCTGCCT GCAAACCTGC TGGTGGGGCA GACCCGAAAA TCCAGCGTGC ACCCCGCCGG AGGAAGGTCC CATGGCCTGC TGGGCTTGGC TCGGCGCCCC CACCCCTGGC TACCTTGTGG  GAATAAACAG ACAAATTAGC CTGCTGGATC TTTCTGCGTA GGGGCTTGGG GGGCCCTTTT GCCAGGGGCC CCTCCATGTC AGGGCCAGTT GCCGTCAGCT GCCAGGCTGG GGGTGCCATG  GAGGTGGCGT GTTGTTGCCC CCTCTTCCTC CAGGCTCGGG GGGCTGTGCT GGCTGCAGTG CTGGGGTGCA GTGAGATCTG GGCCCGTTGG ACACCCAGCC CTGGCTCTTA ATCCGTGCAG  CCCCACCTGC TGTGCACAGG CAGGGCCTGG TGTAGTGCCG AGTCTTGGAG GAGATAATTC TAAGTGGCTG TGCTTCCTGG CCCCGGGCCT TAACTGTTAG GAGGTGGCTA CTGGGGCCTC  CCCTGGCCAG GAAGCAGAAG TGCAGAGGCC CGAGGAACAG CGTGGCCCTG GTGCTGGGGA TGGGTTGGGC ACCCACACCG GCCCTTGGGG CCTCACCTGG CTGGGGGGTG TGGGGGTGGC  TGGGTGGTTA CTGTTTGCAC AGAGTCCCTC CGTGAGGGCT GGGGATGGAC AGGCCAGGAG GGGCTGGTAG AGCAGTACCA GCCACCGTTC ATGGGACCCG GGGGCTGTCT GGACACGGCC  TGGCTGCCCA CCTGCACAGC TAGAGGGACT GCAGCCTGCC AGGGTGGCTG ATCCCAGCTG CCCCCACTGG GGGTCTGTGG AATGGACGGT CCATGGCACC TGCCCCAGAC ACTGGGTTGA  GAGGTCTGTC TCTCCCAGCC CTCGTCCCCT CTCATCCACA TGGGGCCAGC ACAGGCAGTG GGCAGAAAGG CCTGGTAACC AGGAGAGCCT GGGGGGATGC CCACACACCC CTGCCCTTCC 
CTCCCTGTCC CACAGGCTGA GGAGCAGACT CCGTGGGAAG T 

Retrieve as FASTA  
DNA ►
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.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
ATGAGCCTCGGCCGCCTTTGCCGCCTACTGAAGCCGGCGCTGCTCTGTGGGGCTCTGGCCGCGCCTGGCCTGGCCGGGACCATGTGGTGAGCTAGCGCCGCGGCCGTTGCCGGCCCGGTG
ACCGTTGGGGCGGGCGCGCGATCCCTGCCTCCGCTCGCCGGCGTGGGGAACCCTCAGGCTCCAGTGACCTTGGTGGGGGGCGTCTGGGGGCTCCCCCTCCCCACCCCCGGCCGGGCACGG
ACGCGGGTGACCGTACTGCGACGCGCTCCGCGGCCCTCCAGGCCGTTGTAGGCGCGCGGGCTGGGGTCGGGGAAGGGGAAGGGGTTGTTCCACGCGCGCGGGTCGTGGTCGGGGAAGGGG
CCGTCCAGGCCGTTGCAGGCGCGCGTGCCGGGGCCGGGGTCGGGGGTCCAGGCTTGCAGGGGGCGGGGTCCGGGACGGCTGGGGCGGAGCTGGACCGTTGAGGGCCACGGCGGGGCGTCT
CCGGGCCGAGCGGGGCTGCTGCGCCCGAGCGGTTGGGGGCGCGGAGGGCTGGAAATCCCGGATCACGCGCCCCCGGGCGCCGCCCCGCCCCCGCACCTTGGCCTAGCGCGGTGGCGTCAC
AGTCGCGCAGTCCTGACTACGGCCTCCGGGCCCTTTGTCCCCGCTAGCGGCGCTCGGGGTGGGGGAGCCAGGAGGGGCGGGAGACGGGCGGGTATGGGCCGCGCGGGCGCAGGCTCCCCC
GGGCGCCGCAGGCAGCGGTGCCAGAGCCGGGGCAGGCGGCGGCCGCGAGCCCCTCGGCGGCGGAAGGCCCCAGCGTGCAGGCGCAGGAGGGCGCGGCGCCGGCGGAAGAAGCCCTGTCCC
CGCAGCTTGCGACCGGAGATCCACGAATGTCCCAAGTCCCAGGACCCGGTGCGCGCGGGGCCCCCACACCGGCTAATGTGGCACATTTTGGGGTTGGAACCCTCTCCCGGCCTCCGGGTC
TCCGGTAAAACCGGACCAGAAGTACAAGGGGGCGTGTGCGTTTAAGGAGGAGGAGCGTTCAGGTCTTCAGGGCCGCAGGGCCTCGGTGTCCCCGCCACCGACCCGCTCCCGATCCCTTCC
TGCCTCAGGGTCCCGGGCTCAGCCTCCCGTCCACGCTCCCTGCTCAGCTTCCTTTGCCTTGCAGTGCGCGTCCCGGGACGACTGGCGCTGTGCGCGCTCCATGCACGAGTTTTCCGCCAA
GGACATCGACGGGCACATGGTTAACCTGGACAAGTACCGCGGTGGGCGCTCGCCTGGGGTGGGGCGCGGGGTCGGGCCCTGGGAGGGGGCCGTGTTCTTCTGCGCTGACGCCGCCGATCC
TCGCAGGGGCTTCGTGTGCATCGTCACCAACGTGGCCTCCCAGTGAGGCAAGACCGAAGTAAACTACACTCAGCTCGTCGACCTGCACGCCCGATACGCTGAGTGTGGTTTGCGGATCCT
GGCCTTCCCGTGTAACCAGTTCGGGAAGCAGAGGTGGGCTGCTGCGTCCCCGGGGCCCGCAGAGGCGGGTGGGTGGGGGTCGGGGTGGGCTCCAGCCTGGAGAGGGCCTGGGAGTGTGCA
GGGGGCCCGGACTGAGGGGGTGCCAGCCCCCGACTCACTCACACACCTTGGCCGCCACAGGAGCCAGGGAGTAACGAAGAGATCAAAGAGTTCGCCGCGGGCTACAACGTCAAATTCGAT
ATGTTCAGCAAGATCTGCGTGAACGGGGACGACGCCCACCCGCTGTGGAAGTGGATGAAGATCCAACCCAAGGGCAAGGGCATCCTGGGAAAAAGTGCGTGACCTCTGGGGACAGTACGG
CTGCTGGGGTGGGGGTGGGGGGGCTGCTGGGATGCTCACACCTCCCTGGGGCAGAATGGCTCATGGCTCGGGGGGCGGTTGCGGGGAGGTGCTGGGACTCTCACATCGCGTGGCCTCCTG
GGGGTAAGATGGCTCAGGGGGACATAGAGGGCTGTGGAGGCAGCCAGGGATGCCCACACCTTTGTGGCCTCCTGGGGACAGGATGGCTCGGGGGCCTGTGGGGGGCTGTTGGGACTCTCA
CACTGCATGGCCTCCTGGGGTAAGATGGCTCTGGGGGGGCTTGGGGGCACTGTGGCTGTGGAGGCAGCCGGGGAAGCTCACACCCTTGTGGCCTCCTGGAGACAGGACAGCTTGGGGACT
GTGGGGGGCTGCTGGGGACGCTCACGTCCATGTGCTTCTTTTCCAGTGCCATCAAGTGGAACTTCACCAAGAGGTAAGGGGGCTGTGGGGGGTAGGGGACCAGCTTCCCCTGGCCACAGC
CGTGGCCCAGATGGGCAGCGGACAGGAAGGGCAGCCTCAGCCCCTTGCAGGGGTGGCCCCACAGTTTGGACACCGTCTCTCCACAGTTCCTCATCGACAAGAACGGCTGCGTGGTGAAGC
GCTACGGACCCATGGAGGAGCCCCTGTGGTAGGTCCTCTCTAGGGAGCCCGCTTGAGGCTCGGGGGCTTGGGAGGTAGCTGCCCTAACCCAGCTTTCCTCCCCGACAGGTGATAGAGAAG
GACCTGCCCCACTATTTCTAGCTCCACAAGTGTGTGGCCCCGCCCGAGCCCCTGCCCACGCCCTTGGAGCCTTCCACCGGCACTCATGA

Retrieve as FASTA  
CDS►
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.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
ATGAGCCTCGGCCGCCTTTGCCGCCTACTGAAGCCGGCGCTGCTCTGTGGGGCTCTGGCCGCGCCTGGCCTGGCCGGGACCATGTGCGCGTCCCGGGACGACTGGCGCTGTGCGCGCTCC
ATGCACGAGTTTTCCGCCAAGGACATCGACGGGCACATGGTTAACCTGGACAAGTACCGGGGCTTCGTGTGCATCGTCACCAACGTGGCCTCCCAGTGAGGCAAGACCGAAGTAAACTAC
ACTCAGCTCGTCGACCTGCACGCCCGATACGCTGAGTGTGGTTTGCGGATCCTGGCCTTCCCGTGTAACCAGTTCGGGAAGCAGGAGCCAGGGAGTAACGAAGAGATCAAAGAGTTCGCC
GCGGGCTACAACGTCAAATTCGATATGTTCAGCAAGATCTGCGTGAACGGGGACGACGCCCACCCGCTGTGGAAGTGGATGAAGATCCAACCCAAGGGCAAGGGCATCCTGGGAAATGCC
ATCAAGTGGAACTTCACCAAGTTTGGACACCGTCTCTCCACAGTTCCTCATCGACAAGAACGGCTGCGTGGTGAAGCGCTACGGACCCATGGAGGAGCCCCTGGTGATAGAGAAGGACCT
GCCCCACTATTTCTAGCTCCACAAGTGTGTGGCCCCGCCCGAGCCCCTGCCCACGCCCTTGGAGCCTTCCACCGGCACTCATGA

Retrieve as FASTA