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Entry information : RnoTPO
Entry ID 3973
Creation 2006-09-06 (Christophe Dunand)
Last sequence changes 2006-09-06 (Christophe Dunand)
Sequence status complete
Reviewer Filippo Passardi
Last annotation changes 2006-09-06 (Filippo Passardi)
Peroxidase information: RnoTPO
Name RnoTPO
Class Thyroid peroxidase    [Orthogroup: TPO001]
Taxonomy Eukaryota Metazoa Chordata Mammalia Muridae Rattus
Organism Rattus norvegicus (Norway rat)    [TaxId: 10116 ]
Cellular localisation N/D
Tissue type N/D
Inducer N/D
Repressor N/D
Best BLASTp hits
Perox score E-value RnoTPO
start..stop		 S start..stop
MmTPO 1798 0 1..914 1..914
HsTPO01 1419 0 1..905 1..919
GgoTPO 1415 0 1..905 1..917
CjaTPO 1357 0 1..903 1..914
Literature and cross-references RnoTPO
Literature Derwahl M., Seto P., Rapoport B.;
"Complete nucleotide sequence of the cDNA for thyroid peroxidase in FRTL5 rat thyroid cells.";
Nucleic Acids Res. 17:8380-8380(1989).
Protein ref. UniProtKB:   P14650
Cluster/Prediction ref. UniGene:   Rn.91199
Protein sequence: RnoTPO
Sequence Properties
first value : protein
second value (mature protein)
Length (aa):   %s   914 (313)
PWM (Da):   %s   101266.62 (34238.3) Transmb domain:   %s   i5-24o837-859i
PI (pH):   %s   7.08 (9.62) Peptide Signal:   %s   cut: 24 range:24-336
Sequence
Send to BLAST
Send to Peroxiscan
*.........1 .........2 .........3 .........4 .........5 .........6 .........7 .........8 .........9 .........0 .........1 .........2
MRTLGAMAVM LVVMGTAIFL PFLLRSRDIL GGKTMTSHVI SVVETSQLLV DNAVYNTMKR NLKKRGVLSP AQLLSFSKLP ESTSGAISRA AEIMETSIQV MKREQSQFST DALSADILAT  IANLSGCLPF MLPPRCPDTC LANKYRPITG VCNNRDHPRW GASNTALARW LPPVYEDGFS QPRGWNPNFL YHGFPLPPVR EVTRHLIQVS NEAVTEDDQY SDFLPVWGQY IDHDIALTPQ  STSTAAFWGG VDCQLTCENQ NPCFPIQLPS NSSRTTACLP FYRSSAACGT GDQGALFGNL SAANPRQQMN GLTSFLDAST VYGSSPGVEK QLRNWSSSAG LLRVNTLHLD SGRAYLPFAS  AACAPEPGAP HANRTPCFLA GDGRASEVPA LAAVHTLWLR EHNRLATAFK AINTHWSANT AYQEARKVVG ALHQIITMRD YIPKILGPDA FRQYVGPYEG YNPTVNPTVS NVFSTAAFRF  GHATVHPLVR RLNTDFQDHT ELPRLQLHDV FFRPWRLIQE GGLDPIVRGL LARPAKLQVQ EQLMNEELTE RLFVLSNVGT LDLASLNLQR GRDHGLPGYN EWREFCGLSR LDTGAELNKA  IANRSMVNKI MELYKHADNI DVWLGGLAEK FLPGARTGPL FACIIGKQMK ALRDGDRFWW ENSHVFTDAQ RQELEKHSLP RVICDNTGLT RVPVDAFRIG KFPQDFESCE EIPSMDLRLW  RETFPQDDKC VFPEKVDNGN FVHCEESGKL VLVYSCFHGY KLQGQEQVTC TQNGWDSEPP VCKDVNECAD LTHPPCHSSA KCKNTKGSFQ CVCTDPYMLG EDEKTCIDSG RLPRASWVSI 
ALGALLIGGL ASLSWTVICR WTHADKKSTL LITERVTMES GFRKSQESGI SPQKAEVQDA EQEPAYGSRV LLCE 

Retrieve as FASTA  
Remarks Complete sequence from 4 cDNA and 1 EST. Chrom 6. Cell_line=FRTL5.