The peroxidases and oxidases database
Entry information : HsGPx01-B (GSHPx-1 / GPx-1 / HsGPx01-B)
Entry ID 4325
Creation 2007-01-12 (Filippo Passardi)
Last sequence changes 2016-06-28 (Harold Duruflé)
Sequence status complete
Reviewer Not yet reviewed
Last annotation changes 2016-06-28 (Harold Duruflé)
Peroxidase information: HsGPx01-B (GSHPx-1 / GPx-1 / HsGPx01-B)
Name (synonym) HsGPx01-B (GSHPx-1 / GPx-1 / HsGPx01-B)
Class Animal glutathione peroxidase    [Orthogroup: N/D] N/D
Taxonomy Eukaryota Metazoa Chordata Mammalia Hominidae Homo
Organism Homo sapiens (human)    [TaxId: 9606 ]
Cellular localisation N/D
Tissue type N/D
Inducer N/D
Repressor N/D
Best BLASTp hits
Perox score E-value HsGPx01-B
start..stop		 S start..stop
HsGPx01-A 167 1e-54 1..84 1..84
CjaGPx01-B 152 4e-50 14..90 13..89
MmGPx01 149 1e-47 1..84 1..82
PtroGPx01-A 145 6e-46 14..84 12..82
Gene structure Fichier Exons►
ExonStart..EndSize ExonStart..EndSize ExonStart..EndSize ExonStart..EndSize
N° 1 1..297 297  
join(1..297)


exon

Literature and cross-references HsGPx01-B (GSHPx-1 / GPx-1 / HsGPx01-B)
Literature REFERENCE 1 Sukenaga Y., Ishida K., Takeda T., Takagi K. cDNA sequence coding for human glutathione peroxidase.Nucleic Acids Res. 15:7178-7178(1987).

REFERENCE 2 Ishida K., Morino T., Takagi K., Sukenaga Y.Nucleotide sequence of a human gene for glutathione peroxidase. Nucleic Acids Res. 15:10051-10051(1987).

REFERENCE 3 Mullenbach G.T., Tabrizi A., Irvine B.D., Bell G.I., Hallewell R.A. Sequence of a cDNA coding for human glutathione peroxidase confirms TGA encodes active site selenocysteine. Nucleic Acids Res. 15:5484-5484(1987).

REFERENCE 4 Chada S., le Beau M.M., Casey L., Newburger P.E.Isolation and chromosomal localization of the human glutathione peroxidase gene. Genomics 6:268-271(1990).
DNA ref. GenBank:   NC_000003.11 (49395711..49395418)
mRNA ref. GenBank:   NM_201397
Cluster/Prediction ref. Genebank:   2876 UniGene:   Hs.76686
Protein sequence: HsGPx01-B (GSHPx-1 / GPx-1 / HsGPx01-B)
Sequence Properties
first value : protein
second value (mature protein)
Length (aa):   %s   98
PWM (Da):   %s   10004.25  
PI (pH):   %s   10.6
Sequence 0
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.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2

MCAARLAAAA AAAQSVYAFS ARPLAGGEPV SLGSLRGKVL LIENVASLUG TTVRDYTQMN ELQRRLGPRG LVVLGFPCNQ FGHQVRRAER GGAGADVQ 

Retrieve as FASTA  
Remarks Complete sequence from genomic (chromo, no intron), 19 cDNA and 1079 ESTs (transcript variants HsGPx01-a and HsGPx01-b cumulated). Note that the Swissprot accession P07203 only describes HsGPx01a.
Promoter►
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TGGCTGGGGG CGCCGGCGGT GTGCTGGTGG GTGCCGTCGG CTCCATGCGC GGAGAGTCTG GCTACTCTCT CGTTTCCTTT CTGTTGCTCG TAGCTGCTGA AATTCCTCTC CGCCCTTGGG  ATTGCGCATG GAGGGCAAAA TCCCGGTGAC TCATAGAAAA TCTCCCTTGT TTGTGGTTAG AACGTTTCTC TCCTCCTCTT GACCCCGGGT TCTAGCTGCC CTTCTCTCCT GTAGGAGAAC  GCCAAGAACG AAGAGATTCT GAATTCCCTC AAGTACGTCC GGCCTGGTGG TGGGTTCGAG CCCAACTTCA TGCTCTTCGA GAAGTGCGAG GTGAACGGTG CGGGGGCGCA CCCTCTCTTC  GCCTTCCTGC GGGAGGCCCT GCCAGCTCCC AGCGACGACG CCACCGCGCT TATGACCGAC CCCAAGCTCA TCACCTGGTC TCCGGTGTGT CGCAACGATG TTGCCTGGAA CTTTGAGAAG  TTCCTGGTGG GCCCTGACGG TGTGCCCCTA CGCAGGTACA GCCGCCGCTT CCAGACCATT GACATCGAGC CTGACATCGA AGCCCTGCTG TCTCAAGGGC CCAGCTGTGC CTAGGGCGCC  CCTCCTACCC CGGCTGCTTG GCAGTTGCAG TGCTGCTGTC TCGGGGGGGT TTTCATCTAT GAGGGTGTTT CCTCTAAACC TACGAGGGAG GAACACCTGA TCTTACAGAA AATACCACCT  CGAGATGGGT GCTGGTCCTG TTGATCCCAG TCTCTGCCAG ACCAAGGCGA GTTTCCCCAC TAATAAAGTG CCGGGTGTCA GCAGAACTGT GTGTATGTCC TGTGTCATTG TCATTTGGGA  ATTCTTTTTC TTTTCTTTTT TTTTTTTTTT TTTTGAGACG GAGTTTTTTG CTCTATTGCC CAGGCTGGAG TGCAGTGGCG CAATCTAGGC TCACTGCAAG CTCCGCCTCC CGGGTTCACG  CCATTCTCCT GCCTCAACCT CCTGAGTAGC TGGGACTACA GGTGCCTGCC ACCACGCCCG GCTAATTTTT TGTATTTTTA GTAGAGACAG GGTTTCACCG TGTTAGCCAG GATGGTATCG  ATCTCCTGAC CTCGTGATCC ACCCGCCTCG GCCTCCCAAA GTGCTGGGAT TACAGGTATG AGCCACCGCA CCCGGCCTGG CGATACTTTT TCTAACCTCA TTGTCATAGT GGTGGGAACT  TAATCCTCCT TCCCTTATCC TAGCCAAGTC TGAACTTTCT GTCCTTTTGT CTGCAGCGTG TAGGATCCAC TCTTTCCTTT GTGGGAAGTC TGGCTCCTGG CCTGCATTTC TGCCTTCACC  AGAACATGCA AAGGGCCATC TCAAGACCCA GTTACAACAA AGTCCTTACT TCAAAAAAGA CACAAGGCAA TGGTTGACTG CCTAACTCAA ATGATAGACT TCTGACTACT TGCTGCACGC  TGAAATGACT GTCACAAAAT AACATGAGCC CCCACTCACA TTTGGAGTCA TGGCCTCTCC AATTGTTAGG TCCACACAAT CCCATTTTAC ACGGAAGCTC ATGCAATGTT ATAAATTCTG  TTATCTGGCT AGATCTTTCC ATGTTGCTAC CAAGTGCCTG TATCTGCTGT GACGATGATC TTACAAGTTT CTGCCTCATA TATTCAAGAG TGAGAAAACT ATAATTTAAC TGGCCCTTCT  GACTATGCCC TGCCCAACAC TTAACGTGCA ATTAATTGCA CATTCAGGCC CAGGATAAGG GCTTGTCTTT GAAGCCAGCT GCTGCTTCTC GGGCACCACT CAGGTCCAGC CTCTCCATCT  GTTGACCCTG CTGCCAATAA TCTTTAATTT TTTTTTTTTT TTTTTTTTTT TTGAGACAGT CTTGCTCTGT TGCGCAGGCT GGAGTGCAGT GGTGTAATCT CGGCTCACTG CAAGCTCCGC 
CTCCCGGGTT CACGCCATTC TGCCTCAGCC TCCCGAGTAG CTGGGACTAC AGGCGCCCGC CACCACGCCC GGCTAATTTT 

Retrieve as FASTA  
Terminator +►
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Send to cis Analysis
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ATCCAGGTTC CCTCCCAGAG GAGCCACCAG TTCTCATGGG TGGCACTCAG TCTCTCTTCT CTCCAGCTGA CTAAACTTTT TTTCTGTACC AGTTAATTTT TCCAACTACT AATAGAATAA  AGGCAGTTTT CTAAACTTCC TGTATCCTGT TGTTTGTGTT GCTCTCTCCA GGGCTGGGGG TAGGAGGATG CAAGGACTTC CTGGCCTAGC TCACCCTGGA GAGGTTTGTT GAGTGCAAAG  GACTAGCTTG TGCCCCACCT CCCACCCACC CAGCAGCTAA TCTGGTCCCT CCCAACAACA TGGAAATGAT TACCCTGTAC CGCATTCTGG TTCAGATTTG GGGGTAGGGT GAATGCAGCC  TGAGGAGGCC AGGGAGGGAG GACTCCGGCA GCGTTTCCTT GGCCTCGGCG AGCTACTGGG CTCCACTTAA GGAGGCTGGG GCAGAGCTTC CAGGACTCTG CCCGGTTAGA AAACCCGCAC  GAGGGCGGTG CCGCTTTGGA GACAGGGAGG AGGGAGACCG GAAGCCTAGA TCCCTCTGGC TGTCCCCTGC ACTGCCGGTA ACATGGCACA GGAGAGGAGG GCTGTTTGTG CACGGGCAGC  TCCTGCAGCT GCTGCCGTCG CCCACCAGCC TCCTATGCCA AACCCCACAT CCTAACTCAG GAACCTCTGA GAAAAAACGG AGCCCTCGAG GGCCCCAGCC CTTGGAAGGG TAACCTGGAC  CGCTGCCGCC TGGTTGCCTG GGCCAGACCA GACATGCCTG CTGCTCCTTC CGGCTTAGGA GGAGCACGCG TCCCGCTCGG GCGCACTCTC CAGCCTTTTC CTGGCTGAGG AGGGGCCGAG  CCCTCCGGGT AGGGCGGGGG CCGGATGAGG CGGGACCCTC AGGCCCGGAA AACTGCCTGT GCCACGTGAC CCGCCGCCGG CCAGTTAAAA GGAGGCGCCT GCTGGCCTCC CCTTACAGTG 
CTTGTTCGGG GCGCTCCGCT GGCTTCTTGG ACAATTGCGC C 

Retrieve as FASTA  
DNA ►
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ATGTGTGCTG CTCGGCTAGC GGCGGCGGCG GCGGCGGCCC AGTCGGTGTA TGCCTTCTCG GCGCGCCCGC TGGCCGGCGG GGAGCCTGTG AGCCTGGGCT CCCTGCGGGG CAAGGTACTA  CTTATCGAGA ATGTGGCGTC CCTCTGAGGC ACCACGGTCC GGGACTACAC CCAGATGAAC GAGCTGCAGC GGCGCCTCGG ACCCCGGGGC CTGGTGGTGC TCGGCTTCCC GTGCAACCAG 
TTTGGGCATC AGGTGCGCCG GGCGGAGCGG GGCGGGGCGG GGGCGGACGT GCAGTAG 

Retrieve as FASTA  
CDS►
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.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
ATGTGTGCTG CTCGGCTAGC GGCGGCGGCG GCGGCGGCCC AGTCGGTGTA TGCCTTCTCG GCGCGCCCGC TGGCCGGCGG GGAGCCTGTG AGCCTGGGCT CCCTGCGGGG CAAGGTACTA  CTTATCGAGA ATGTGGCGTC CCTCTGAGGC ACCACGGTCC GGGACTACAC CCAGATGAAC GAGCTGCAGC GGCGCCTCGG ACCCCGGGGC CTGGTGGTGC TCGGCTTCCC GTGCAACCAG 
TTTGGGCATC AGGTGCGCCG GGCGGAGCGG GGCGGGGCGG GGGCGGACGT GCAGTAG 

Retrieve as FASTA