The peroxidases and oxidases database
Entry information : Hs2CysPrx02 (TSA / NKEF B / PrxII)
Entry ID 4475
Creation 2007-01-25 (Nicolas Rouhier)
Last sequence changes 2010-12-03 (Myriam Duval (Scipio))
Sequence status complete
Reviewer Filippo Passardi
Last annotation changes 2010-12-03 (Myriam Duval (Scipio))
Peroxidase information: Hs2CysPrx02 (TSA / NKEF B / PrxII)
Name (synonym) Hs2CysPrx02 (TSA / NKEF B / PrxII)
Class Typical 2-Cysteine peroxiredoxin    [Orthogroup: 2CysPrx001]
Taxonomy Eukaryota Metazoa Chordata Mammalia Hominidae Homo
Organism Homo sapiens (human)    [TaxId: 9606 ]
Cellular localisation N/D
Tissue type Mixed tissues
Inducer N/D
Repressor N/D
Best BLASTp hits
Perox score E-value Hs2CysPrx02
start..stop		 S start..stop
Ptro2CysPrx02-1 407 6e-148 1..198 1..198
Mmul2CysPrx02 407 6e-148 1..198 1..198
Mfa2CysPrx02 407 6e-148 1..198 1..198
Ggo2CysPrx02 407 6e-148 1..198 1..198
Gene structure Fichier Exons►
ExonStart..EndSize ExonStart..EndSize ExonStart..EndSize ExonStart..EndSize
N° 1 12911973..12912075 103 N° 2 12911730..12911883 154 N° 3 12910991..12911113 123 N° 4 12910673..12910803 131
N° 5 12907895..12907980 86  
complement(join(12907895..12907980,12910673..12910803,12910991..12911113,1291173 0..12911883,12911973..12912075))


exon

Literature and cross-references Hs2CysPrx02 (TSA / NKEF B / PrxII)
Literature Lim Y.-S., Cha M.-K., Kim H.-K., Kim I.-H. The thiol-specific antioxidant protein from human brain: gene cloning and analysis of conserved cysteine regions. Gene 140:279-284(1994).
Protein ref. UniProtKB:   P32119
DNA ref. GenBank:   NC_000019.9 (12912075..12907895)
mRNA ref. GenBank:   CAA80269
Cluster/Prediction ref. UniGene:   Hs.432121
Protein sequence: Hs2CysPrx02 (TSA / NKEF B / PrxII)
Sequence Properties
first value : protein
second value (mature protein)
Length (aa):   %s   198 (307)
PWM (Da):   %s   21764.2 (33397.0)  
PI (pH):   %s   5.36 (7.98) Peptide Signal:   %s   cut: 33 range:33-339
Sequence 382
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Send to Peroxiscan
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSNRAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLKTDEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGVCPAGWKPGSDTIKPNVDDSKEYFSKHN

Retrieve as FASTA  
Remarks Complete sequence from Genomic (Chromo 19, 4 introns). 29 mRNA. 1488 ESTs.
DNA ►
Send to BLAST
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
ATGGCCTCCGGTAACGCGCGCATCGGAAAGCCAGCCCCTGACTTCAAGGCCACAGCGGTGGTTGATGGCGCCTTCAAAGAGGTGAAGCTGTCGGACTACAAAGGTGAGCGCCGCCCGGAG
GGGGCCCAGGTAGAAGCGGGGCCGTGCATGAGAGAAGCTGGGCCCTAACTCCTCTGTGTCCCTCCTCCCCAGGGAAGTACGTGGTCCTCTTTTTCTACCCTCTGGACTTCACTTTTGTGT
GCCCCACCGAGATCATCGCGTTCAGCAACCGTGCAGAGGACTTCCGCAAGCTGGGCTGTGAAGTGCTGGGCGTCTCGGTGGACTCTCAGTTCACCCACCTGGCTTGGTATGAGCAGGGGC
CAAAGAGGGAGGTTGCAGCTAAGCTCACACCCTCAGGTCCTAGCAGTGTGGCTTCGTGGCCATTGCTCAACCTCTGGAACCTGCGTTTCCCCATCGTGAAAATAATGGAAACATTGCCGC
CCAAGTCTTTAAGGATGATGACAGTAATTAGCATTTGACAACTAGTTGCCTGGTATATAGAGTTGCAGATGCAACTCAGATGCAACTCTATCTACTCTATGTACTTAGTTCCCAGGAGGG
AGGCTGTGCTGCCCTATTTCATGAAGATGGAAACTCCAGTTCACCGAAGTGAAGGGCTGTACCCCATGACACAGCTAGAGGAGGATGGGGACTCTTAACACAGGCTCTCTGCTGGGTGAT
GCTGCAAGTTACAAGTACATGTGAAGCCACTTAGCTGGAGCTGTGCCTCTCAAACTCAGTCTTCCCAGCCATGGGGATACAGTCCTTGCACCCAACCCAGGGTGGGGTGGGTGAGGCTCC
CAGCGGCCTACTCTAAAGCCCCTTATCTCCGGCCTCCAGTGCTTATCACATTGGGCCCACAGGGTGAGGACCCTGCTGTGCCAGGCATCCTGAGGCCCCAACTCTGTCTCCCCTACTCCC
AGGATCAACACCCCCCGGAAAGAGGGAGGCTTGGGCCCCCTGAACATCCCCCTGCTTGCTGACGTGACCAGACGCTTGTCTGAGGATTACGGCGTGCTGAAAACAGATGAGGGCATTGCC
TACAGGTACTGTGGGACCCTCAGCCCGGCTCAGGGAGCGCCCTGCCCCCCATTCCTGTGATGCTGGGACCACTCCTGTACAATGTCTTCTCTGCCCCCAGCCCTGTGGCTAGCAGCGGGT
GGTTGGTAGTCCCTTCCTTGTCTCTGGCAGTGGGAGCTATCAGCTCCTCACTGGGAACCCTGATGTCTTCAGGGGCCTCTTTATCATCGATGGCAAGGGTGTCCTTCGCCAGATCACTGT
TAATGATTTGCCTGTGGGACGCTCCGTGGATGAGGCTCTGCGGCTGGTCCAGGCCTTCCAGTACACAGACGAGCATGGGGAAGGTGAGCAGATACACACATGACACATGGGTACATACTG
AGCGCCTCCGTCACTCATGCAAACATTCACTGCCTGTCCTCTTACCTGTCCAGATGGGTGTTAGGGCCCCAAAGAAGATTCAGCTCAGGGCTTTGTCTGCAGGATGTTTCTAATGTGGTA
GGAGACAAATAACGCCTGACATTCAACCAAGGTGGACAAAGGGGCCGGGCTCAGTGGCTCACGGTTGTATTGCCAGCACTTTGGGAAGCTGTGGCAGGTGGATCACCTGAGGTCAGGAGT
TCGAGACCAGCCTGACCAACATGGTGAAACCCCGTCTCTACGAAGAACACAAAAAATTAGCTGGCCGTGGTGGTGCACACTTGTAATCCCAGCTACTTGAGAGACTGAGGCAGGAGTTCG
CTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATCGCACCGTTGTACTCCAGCTTGGGCAACAGAGCAAAACTCAGTCTCAAAAAAAAAAAAAATTAGCTTGGTTTGTGAAGCATG
CCTATAGTCCCAGCTACTCAAGAGGCTGAGGCTGGAGGATCACTTGAGCCTGGGAGGTCAAGGCTGCAGTAAGCTGTGATCGCACCACTGCACTCCAGCCTGGGTGACACAGCAAGACCC
TGTCTCAAAAAAACAAACAAACAGGCCGAGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCAGATCATGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACA
TAGTGAAACCGCGTCTCTGCTAAAAATACAAAAAAATTAGCTGGGTGCGGTGGCAGGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGACTCCCTTGAACCCGGGAGGAGGT
TGCAGTAAGCCGAGATCACACCACTGCACTCCAGCCTGGGCGCCAGTGTGAGACTCCATCTCAAAAACAACAACAACAAAAAAACCTGTAGGGGTGGGGCAGAGGGACAAAGATGGGACT
AAAGGAGCCAAAAAGACAGGAAGATGCTGTGTCTCATGCCTGTAGATGCTGTGTCTCATGCCTGTAGTTCCACCTACTCTGGAGAGTGAGGCAGAAGATTGCTTAGGCCCAGGAATTTGA
GTCGAGCCTAGGCAACATAGCAATACCCCATCTCTTTTTTTTTTTTTTTAAGAGATGGGGTATTGGTTAAAAAAAAAAAAAAAAAAAAAGAGGCCAGATGCAGTGGCTCACACCTGTAAT
CCCAGCATTTTGGGAGGCCTAGGTGGGTGGATCACCTGAGGTCGGGAGTTCGAGACAAGCTTGACCGACATGGAGAAACCCAGTCTCTACTAAAAATACAAAATTAGCCCAGCCTGGTGG
TGCATGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAAGAGAATCGTTTGAAGCTGAGAGGCGGAGGTTGCAGTGAGCTGAGATCGTGCCATTGCACTCCAGCCTGGGCAACGAGTGA
AGCGAAACTCCGTCTCAAAAAATAAAAAAAAAAAAGAGGCCGGGCACGGTGGCTCATGCCTGTAATCCCACCACTTTGGGAGGCTGAGGCGGGCGGATCAAGAGGTCAGGAGATCGAGAC
CATCCTAGCTAACGCGGTGAAACCCTGTCTCTACTAAAAATACAAAAAAATTAGTCGGGCGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTCTGGCGGCTGAGGTAGGAGAATGGCGTGA
ACCTGGGAGGCGGAGCTTGCAGTGAGCAGAGATCGTGCCACTGCACTCCAGCCTGGGCAACAGAGCAAGACTCCATCTTAAAAAAAAAGAAAAGAAAAAAAGAAGAAAAAGGAGAGCTGG
GTGGCAAAAAGAAATTGAAGAATTAAGAGTAGGAAAAACACCAGCTAGAAAATACTGAACTTGGCCAGGTGTAGTGGCTCACGCCTGTAATCCTAGCATTTTGGGAGGCCAAGGTGGGTG
GATCACCTGAAGTCAGGAGTTCGAGATCAGCCTGACCAATATGGTGAAACCCTGTCTCTGCTAAAAGTACCAAAAAATTAGCAGGGTGTGGTGGCGGGCACTTGTAGTCCCAGCTACTCA
GGAGGCTAAGGCAGGAGAATCACTTGAACGCGGGAGGCAGAGGTTGCAATGAGCCGAGATCACGCCATTGCACTCCAGCCTGGGCAACAGAGGAGGACTCTGTCTCAAAAAAAAAAAAAA
AAAAAGAAAGAAAGAAAAAAGAAGAAAAGAAAAAGAGAAAATACTGAACTTGGCTAGGCATGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCAAGACGGGCAGATGACTTGAG
GTCAGGAGTTCGAGACAAGCGTGACTAACATGGTCTCTACCAAAAATACAAAAATTAGCCAGGCGTGGTGGTGCACCTCTGTAATTCCAGCTAGGGAGTCTGGGGCATGAGAATCGCTTG
AACCCAGGAGGGAGAGGTTGCATGAGCTCAGATCATGCTACTGTACTTCAGCCTGGGCAACAGAGCAAGACTCTGTCTGAAAAAAAAAAAAAAGAAAAAATACTGAACTGGGCTTGGAGG
GTTTATCTTAATATCCACATTCCTGGGCCTGGACCACTTGCTTCCAGCATTTTCTTCTGCAACACAGGCCCTTGCTTTGCTTCACCTTGAACCTGGGGCTGTAGCCTTCATGTGCATCCT
TGTGTCTTCCCACAGTTTGTCCCGCTGGCTGGAAGCCTGGCAGTGACACGATTAAGCCCAACGTGGATGACAGCAAGGAATATTTCTCCAAACACAATTAG

Retrieve as FASTA  
CDS►
Send to BLAST
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
ATGGCCTCCGGTAACGCGCGCATCGGAAAGCCAGCCCCTGACTTCAAGGCCACAGCGGTGGTTGATGGCGCCTTCAAAGAGGTGAAGCTGTCGGACTACAAAGGGAAGTACGTGGTCCTC
TTTTTCTACCCTCTGGACTTCACTTTTGTGTGCCCCACCGAGATCATCGCGTTCAGCAACCGTGCAGAGGACTTCCGCAAGCTGGGCTGTGAAGTGCTGGGCGTCTCGGTGGACTCTCAG
TTCACCCACCTGGCTTGGATCAACACCCCCCGGAAAGAGGGAGGCTTGGGCCCCCTGAACATCCCCCTGCTTGCTGACGTGACCAGACGCTTGTCTGAGGATTACGGCGTGCTGAAAACA
GATGAGGGCATTGCCTACAGGGGCCTCTTTATCATCGATGGCAAGGGTGTCCTTCGCCAGATCACTGTTAATGATTTGCCTGTGGGACGCTCCGTGGATGAGGCTCTGCGGCTGGTCCAG
GCCTTCCAGTACACAGACGAGCATGGGGAAGTTTGTCCCGCTGGCTGGAAGCCTGGCAGTGACACGATTAAGCCCAACGTGGATGACAGCAAGGAATATTTCTCCAAACACAATTAG

Retrieve as FASTA