The peroxidases and oxidases database
Entry information : Tcr2CysPrx (mpx)
Entry ID 4496
Creation 2007-02-01 (Nicolas Rouhier)
Last sequence changes 2012-05-24 (Christophe Dunand)
Sequence status complete
Reviewer Not yet reviewed
Last annotation changes 2012-05-24 (Christophe Dunand)
Peroxidase information: Tcr2CysPrx (mpx)
Name (synonym) Tcr2CysPrx (mpx)
Class Typical 2-Cysteine peroxiredoxin    [Orthogroup: 2CysPrx001]
Taxonomy Eukaryota Trypanosomatidae Trypanosoma
Organism Trypanosoma cruzi    [TaxId: 5693 ]
Cellular localisation Mitochondria
Tissue type N/D
Inducer N/D
Repressor N/D
Best BLASTp hits
Perox score E-value Tcr2CysPrx
start..stop		 S start..stop
Tbr2CysPrx 383 2e-137 1..225 1..225
Lm2CysPrx 358 1e-127 1..225 1..225
Linf2CysPrx 354 5e-126 1..225 1..225
Ldon2CysPrx 353 2e-125 1..225 1..225
Literature and cross-references Tcr2CysPrx (mpx)
Literature Wilkinson S.R., Temperton N.J., Mondragon A., Kelly J.M. Distinct mitochondrial and cytosolic enzymes mediate trypanothione-dependent peroxide metabolism in Trypanosoma cruzi. J. Biol. Chem. 275:8220-8225(2000).
Protein ref. GenPept:   CAA06923 UniProtKB:   O79469
DNA ref. GenBank:   AJ006226
Protein sequence: Tcr2CysPrx (mpx)
Sequence Properties
first value : protein
second value (mature protein)
Length (aa):   %s   226
PWM (Da):   %s   25435.07  
PI (pH):   %s   7.92
Sequence 0
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Send to Peroxiscan
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MFRRMAVTSL QKGLSRRAFC NTLRLLNLDY QAYKTATVRE AAPEWAGKAV VNGKIQDISL NDYKGKYVVL LFYPMDFTFV CPTEITAFSD AQAEFDKINT QVVAVSCDSQ YSHLAWINTP 
RNKGGLGEMS IPVLSDLTKE IARDYGVLIE EQGISLRGLF IIDDKGILRH ITVNDLPVGR NVEEVLRVVQ AFQYVDKNGD VIPCNWRPGK PTMKTEKANE YFEKNA 

Retrieve as FASTA  
Remarks Complete sequence from genomic (no intron). Strain="CL-Brener".
DNA ►
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ATGTTTCGTC GTATGGCCGT GACTTCGTTG CAGAAGGGTC TTTCACGCCG GGCTTTCTGC AACACCCTGC GACTTCTTAA CCTGGACTAC CAAGCATATA AGACTGCCAC GGTGCGCGAG  GCAGCACCTG AGTGGGCAGG AAAAGCTGTC GTGAATGGAA AAATCCAGGA CATCAGCTTG AATGACTACA AGGGCAAGTA TGTTGTTCTT CTTTTTTATC CTATGGATTT TACCTTTGTG  TGCCCCACAG AAATCACAGC CTTTTCAGAT GCTCAGGCAG AATTTGATAA GATTAACACC CAGGTCGTGG CTGTATCATG CGACAGCCAA TATTCACACC TTGCTTGGAT AAACACTCCA  AGAAATAAAG GTGGCCTTGG GGAAATGAGT ATTCCTGTGC TTTCTGATCT CACCAAGGAA ATTGCCCGCG ACTATGGAGT TTTGATCGAG GAGCAAGGGA TCTCTCTGCG CGGACTGTTC  ATCATTGACG ATAAAGGGAT TCTGCGCCAC ATCACGGTGA ATGACTTGCC AGTGGGCAGA AATGTTGAAG AGGTGCTTCG GGTTGTGCAG GCGTTTCAGT ATGTGGACAA AAACGGAGAT 
GTAATTCCAT GTAACTGGAG GCCAGGCAAA CCGACAATGA AAACTGAGAA GGCAAATGAA TATTTTGAGA AAAACGCATG A 

Retrieve as FASTA  
CDS►
Send to BLAST
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ATGTTTCGTC GTATGGCCGT GACTTCGTTG CAGAAGGGTC TTTCACGCCG GGCTTTCTGC AACACCCTGC GACTTCTTAA CCTGGACTAC CAAGCATATA AGACTGCCAC GGTGCGCGAG  GCAGCACCTG AGTGGGCAGG AAAAGCTGTC GTGAATGGAA AAATCCAGGA CATCAGCTTG AATGACTACA AGGGCAAGTA TGTTGTTCTT CTTTTTTATC CTATGGATTT TACCTTTGTG  TGCCCCACAG AAATCACAGC CTTTTCAGAT GCTCAGGCAG AATTTGATAA GATTAACACC CAGGTCGTGG CTGTATCATG CGACAGCCAA TATTCACACC TTGCTTGGAT AAACACTCCA  AGAAATAAAG GTGGCCTTGG GGAAATGAGT ATTCCTGTGC TTTCTGATCT CACCAAGGAA ATTGCCCGCG ACTATGGAGT TTTGATCGAG GAGCAAGGGA TCTCTCTGCG CGGACTGTTC  ATCATTGACG ATAAAGGGAT TCTGCGCCAC ATCACGGTGA ATGACTTGCC AGTGGGCAGA AATGTTGAAG AGGTGCTTCG GGTTGTGCAG GCGTTTCAGT ATGTGGACAA AAACGGAGAT 
GTAATTCCAT GTAACTGGAG GCCAGGCAAA CCGACAATGA AAACTGAGAA GGCAAATGAA TATTTTGAGA AAAACGCATG A 

Retrieve as FASTA