The peroxidases and oxidases database
Entry information : Hs2CysPrx01 (PAG / NKEF A / PrxI)
Entry ID 4501
Creation 2007-01-25 (Nicolas Rouhier)
Last sequence changes 2010-12-03 (Myriam Duval (Scipio))
Sequence status complete
Reviewer Filippo Passardi
Last annotation changes 2010-12-03 (Myriam Duval (Scipio))
Peroxidase information: Hs2CysPrx01 (PAG / NKEF A / PrxI)
Name (synonym) Hs2CysPrx01 (PAG / NKEF A / PrxI)
Class Typical 2-Cysteine peroxiredoxin    [Orthogroup: 2CysPrx001]
Taxonomy Eukaryota Metazoa Chordata Mammalia Hominidae Homo
Organism Homo sapiens (human)    [TaxId: 9606 ]
Cellular localisation N/D
Tissue type Mixed tissues
Inducer N/D
Repressor N/D
Best BLASTp hits
Perox score E-value Hs2CysPrx01
start..stop		 S start..stop
Ptro2CysPrx01-1 412 1e-149 1..199 1..199
Pabe2CysPrx01 411 2e-149 1..199 1..199
Mnem2CysPrx 411 2e-149 1..199 1..199
Mmul2CysPrx01 411 2e-149 1..199 1..199
Gene structure Fichier Exons►
ExonStart..EndSize ExonStart..EndSize ExonStart..EndSize ExonStart..EndSize
N° 1 45984610..45984715 106 N° 2 45981326..45981479 154 N° 3 45980545..45980667 123 N° 4 45980179..45980309 131
N° 5 45977001..45977086 86  
complement(join(45977001..45977086,45980179..45980309,45980545..45980667,4598132 6..45981479,45984610..45984715))


exon

Literature and cross-references Hs2CysPrx01 (PAG / NKEF A / PrxI)
Literature Prosperi M.T., Ferbus D., Karczinski I., Goubin G. A human cDNA corresponding to a gene overexpressed during cell proliferation encodes a product sharing homology with amoebic and bacterial proteins. J. Biol. Chem. 268:11050-11056(1993).
Protein ref. UniProtKB:   Q06830
DNA ref. GenBank:   NC_000001.1 (45984715..45977001)
mRNA ref. GenBank:   CAA48137
Cluster/Prediction ref. UniGene:   Hs.180909
Protein sequence: Hs2CysPrx01 (PAG / NKEF A / PrxI)
Sequence Properties
first value : protein
second value (mature protein)
Length (aa):   %s   199
PWM (Da):   %s   21968.19  
PI (pH):   %s   7.96
Sequence 318
Send to BLAST
Send to Peroxiscan
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGVCPAGWKPGSDTIKPDVQKSKEYFSKQK

Retrieve as FASTA  
Remarks Complete sequence from Genomic (chromo 1, 4 introns), 16 mRNA and 2795 ESTs.
DNA ►
Send to BLAST
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
ATGTCTTCAGGAAATGCTAAAATTGGGCACCCTGCCCCCAACTTCAAAGCCACAGCTGTTATGCCAGATGGTCAGTTTAAAGATATCAGCCTGTCTGACTACAAAGGTGAGAGAATTAAC
ACTGGGCTCATTGAGATGGAGTTATTTTATATTCTAGGGGTGGCTTGTTAGATTTGTGTCAATGTTGTTTGACTGTAAAATGTTTTGTCTCCTAGGAAGAAGTATTTAGGTTGTTACCTT
CATGTTGAAGTGGTGATTATCAAGTGATTACAGGGTATATATCCTAGGACCAAACCACTTCTGGAGAAACCACATGCTTCATTATGTCTGGACATACTAGCTCAATTATCTTTTCAGTAT
TCCTCGTCTATTTTCTTTCTTTATTTTTATTTTTGAGACAGGGTCTCATTCTGTCACCCAGGCTGGAGTGCAGTGGCGCAGTCATGGCTCACTGCAGCCTCTACCTCTCTGGGCTCAGGT
GGTCCTCCTACCTCAGCCTCCCAAGTAGCTGGGACTGTAGGGGCATGCTGCCATGCCTGGCTAATTTTTGTACTTTTTTTTTTTTTTTTTTTTTTTGAGATGGAGTTTTGCTCTTGTTGC
CCAGGCTAGAGTGCAATGGCGTGATCTCGGCTCACCACAACCTCCACTGCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCATGCGCCATCATGCCT
GGCTAATTTTTTTTTGTATTTTTAGTAGAGACGGGGTTTCTCCATGGTGGTCAGGCTGGTCTCGAACTCCTGACCTCAGATGATCCGCCCACCTCGGCGTCCCAAAATGCTGGGATTACA
GGCATGAGCCACCACGCCTGGCTTAATTTTTGTACTTTTTGTAGAGCTGGGCGCCATGTTGCCCAGGCTGGTCTCCAACTCCTGGGCTCAAGCCCTCTGCCTGCCCTAGCCTTTCAAAGT
GCTGGGATAACAGGTGTGAGCCACTGCCTCTGGCCCTCCTCTATTTTATTATTGGAGAAATACTCATTATCTCTTGTTATAAGAGACATTCTACATTTAAAGTCTCAGAGCTCACTCAAA
TCTCTGGAGCTGTGACACTGCTCGTTCAGTTTGTTTGGGTCACGTATATATCACAGCTGTTAATATTAGGCTGAGGGCTAGGCACTTTCCCTTGCCTGTTTTGACCCCGGAGGAGAGTTG
ATATTACAGATGGAACAACTCTCCTTTCTGTTGTCATAGTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTTTGTCGCCCAGGCTAGAGTGCAGTGGTGCGATCTCAGCTCAC
TGCAAGCTCCGCCTTCTGGGTTCATGCCATTCTCAGGCCTCAGCCTCTTGAGTAGCTGGGACTACAGGCGCCCGCAACCATGCTTGGCTAATTTTTTTGTATTTTTAGTAGAGACGGGGT
TTCACCATGTTTGCCAGGATGGTCTCGATCTCCTGACCTTGTGATCCGCCTGCCTTGGCCTCCCAAAGTTCTGGGATTACAGGCGTGAGCCACTGCGCCCGGCCTCTGTTGTCATAGTTT
CATGCAGACACTTGGCAAGTTCTGTTGAGGCTCCTCCTTTCTTTACCTTGTAGTTCCAGAGCAGCTCGATCTCCTGGGACAGTTGAGGATATAGATTCCTTAGAATGCTAACCTGAAACT
CAGGTGTCAAGTGTCCTTTTCTCAGTGGTGTAGCATTAGTCCCTGGAGTTAGTTTTTGGTAGAACATTTGACTAGGTTTCCTGACATAATCACACTTTGTTCTTGGGGCTTCTCCCAGCA
AACAAGGTAAGTTGCACCATAGGGAGGTGACCTGGGCCCAGGGGTATAAGCAGGAGGTCTAGGAGGAGCTGTTCTCTGCCCTCCAGAGCTTGACCTGCTGAGGCCCCAAAGTGCTTGTTA
GGCAAAGCTGGAAGGGTTGTTTAGATGAGTTAGTTTCCAGTGATACTGCAAAGTGGTAAATGTCAAAAAGGGCTGCTTGTTTGGCTTTTTTTTTTTTTTTTTGAGGTGGAATTTTGATCT
TGTCGCACAGGCTGTAGTGCAGTGGCATGATCTCAGGTCACTGCGACCTCCATCTCCCCGGTTCAAGTGATTCTCCTGGCTCAGCCTCCCCAGTAGCTGAGATTTCAGGCCCCCGCTGTC
ACACCCAGCTAATTTTTGTATTTTTAGTAGAGACATGTTTTACCATGTTGGTCAGCCTGGTCTTGAACTCCTGACCTCAGGTGATCCACCCGCCTCGGCCTCCCAAACTGCCTCCCAAAC
TGCTGGGATTACAGACGTCAGCCACCATGCCACCACACCCAGCCTGTTTGACTTTTCAAACATTGCTGCTACCTGGAAATGAGTGAATATTTGGAATTGTTCTAGTATTTAAGCCTGGTG
GGTGTGGCGAGAAGGCTGCCTGGCCAGTTTGAAGATCTGTTATTTCAGTGGTTAATCCCAGTGACTTCATTAAAATTGCAGCTAGAAGTTCTGTTACTCACTAGTACTTTTGTCTTTTCT
GTCTCTCTCTGTCTCCCTCTTTCTCTCTCTCTCTCTGTGTATATGTATATATATATTTCTGTTGTTTTGAGACAGTCTTGCTGTGTTGCCCAGGCTGGCCTCAAACTCCTGGGGTCAAGG
GATCCTCCCACCTCAGCCTCCCAAGTAGCTGGGACTACAGACACGCACCACTGTGCCTGGCTTAAAATTTTTCCTGTCCTGTCAGGCACGTTAGGAACACATGTGATCACTTAAACCATG
CTTGTTCCATTACTATGGTTCATCACGGGAGAAGTGCAAAGGCTGTGACTTCTTATTGGTGTCTTATCTCTACAGCAGAGGAGTACTGCAATTCAGCTTTCTCTGGGTATTGTTAAGCAT
TGGCATTAGGCCATGCTTATAAGTGCATCCTTGCTTTTGCTATCTTTGGAGAACTTGGTGTTTATGTTAATTTTAGCCACTCAGAAAAGATCAAAATTAGACTGAACAGTGTTTACTCTG
TATTGGTAGCTATGACATGGAGGCAGGAGAATAAAGTATGGGATTGGAAGTTTTTTTCATTCAGGTATTCCTAATGCACCAGGTTCTAAAAGTAGCTTCTAGGAGACATCTGTATTGAGC
ATCTTGGCAGTTAGTGGTTATTGTGTCAGCCATCAACTTGCTTCTTTTTGTATAGGAAAATATAAAGCAAGGAAGTCTGTGTCAAATGCTAACCATGACTCCGATTTTCCCCCCAGGAAA
ATATGTTGTGTTCTTCTTTTACCCTCTTGACTTCACCTTTGTGTGCCCCACGGAGATCATTGCTTTCAGTGATAGGGCAGAAGAATTTAAGAAACTCAACTGCCAAGTGATTGGTGCTTC
TGTGGATTCTCACTTCTGTCATCTAGCATGGTAAATCTCTTGGTCTATTTGGCATGTGAACTTTTTTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTTGCTTTGTCGCCCAGGCTGGAGT
GCAGTGGTGTGATCTCCGCTCACTTCAAGCTCTGCCTCCCAGTTTCACGCCATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCGCCTGCCACCATACCTGGCTAATTTTTT
GTATTTTCAGTAGAGACGGTGTTTCACCGTGTTAGTCAGGATGTTCTTGATCTCCTGACCTCGTGATCTGCCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACTGCAC
CTGGCTGGCATGTGAACTTTTAAAACAGCAACTGGGAAGCTTTGGCAATAGACTTTCAAGTATTGCCTTCTCATTGAAGGGAGTGCAAAGTCTGACTTTCTCTTATTGCTCTCATGACCT
GGCAGCAGAGAAGAAGCAGCTTCAATTGCAGTTGAGTGTACCCTAGTGACCTACCTTAACTGTTCTCAGCATTCACTTTATTGCTGGAAAACGGAAAAAAAACAGTCTTTTTGGAAAGTT
AGATTAGGAATATGGGAAAGGGGAAAGAGGAATGCGTACAGTCAAGTCAAGAGTTTGAATGTAACTGTATGTTTGCCTTTTGCCATAGGGTCAATACACCTAAGAAACAAGGAGGACTGG
GACCCATGAACATTCCTTTGGTATCAGACCCGAAGCGCACCATTGCTCAGGATTATGGGGTCTTAAAGGCTGATGAAGGCATCTCGTTCAGGTATGTCATCAGGACAAGTATCCAGTTGG
CTGAAAGCCTTTTATTTGGAGAGATCTAGAGCCCTGATCTGTAGAGACTCCTTGTCATTTCATTCCTTTATGCAGGGGCCTCCTCACTAAGGCCAGGCCAGTAGGAGTGTGGAGACCAGT
CCATTTCCTTCAGGCTTCAAGCCTCTGTATTCTAACAAAGCACATCTCTAAACCTGTATTGCTTTTCCTTTCATCTCTTTTCCCAGGGGCCTTTTTATCATTGATGATAAGGGTATTCTT
CGGCAGATCACTGTAAATGACCTCCCTGTTGGCCGCTCTGTGGATGAGACTTTGAGACTAGTTCAGGCCTTCCAGTTCACTGACAAACATGGGGAAGGTAAGCCATCTGTCTGATAACAG
GACAACAGAGTGGTGGTATGAAGGGGTGGGTTGCCCCTTCACACCTGTGGGTGTTTCTCGTTAGGTGGAATGAGAGACTTGGAAAAAGACACGTAGACAAAGTATAGAGAAAGAAATAAG
GGGGCCCAGGGGACCAGTGTTCAGCATACAGAGGATCCCGCCGGCCTCTGAGTTCCCTTAGTATTTATTGATCATTCTTGGGTGTTTCTCGGAGAGGGGGATGTGGCAGGGTCATAGGAT
AATAGTGGAGAGAAGGTCAGCAGATAAACACGTGAACAAAGGTCTCTGCATCATGAACAAGGTAAAGAATTAAGTGCTGTGCTTTAGATGTGCATACACATAAACATCTCAATGCCTTAA
AGAGCAGTATTGCTGCCCGCATGTCCCACCTCCACCCCTGAGGCGGTTTTCCCCTGTCTCAGTAGATGGAACATACAATTGGGTTTTACACTGAGACATTCCATTGCCCAGGGACTGGCT
GGAGACAGATGCCTTCCTCTTGTCTCAACTGCAAAGAGGCGTTCCTTCCTCTTTTACTAATCCTCCTTAGCACAGGGTGTCAGGCTGGGGGACCCCGGTCAGGTCTTTCCCTTCCCACGA
GGCCATATTTCAGACTATCACATGGGGAGAAACCTTGGACAATACCTGGGTTTCCTAGGCAGAGGTCCCTGTGGCCTTCCGCAGTGTTTGTGTCCCCGGATACTTGAGATTAGGGAGTGG
TGATGACTCTTAAAACGAGCATGCTGCCTTCAAGCATTTGTTTTAACAAAGCATATCTTGCACAGCCCTTAATCCATTTAACCCTGAGTTGACACAGCACATGTTTCAGGGAGCACAGGG
TTGGGGATAAGGTTACAGATTAACAGCATCTCAAGGCAGAAGAATTTTTCTTAGTACAGAACAAAATGGAGTCTCCTCTGTCTACTTCTTTCTACACAGAGACAGTAACAATCTGATCTC
TCTTTTCCCCACAGTGGTAGAATGGGAAAGATAGTAGGAACAGAAGCTACCAAATAAGAAAATGGGTATCTCTCTTCATAAATTGAAGCCCCTGGATTACAGTGTGTTGTGAGGGTGAGG
GTAATGGAAAAGCTTGGGAAGGAGAATATAAAGGCTTTTTATTCAAAGTATACATACTCCTCTCTTCTGTCCTGCTCATTTAGAATCAGTCACTCCCAAAGATCTAACTTACTGAATGTA
GGATGATCTCACAGATGTATTAGGGCAAAACAAAATGGTTGGGAATCACCTCTAGAGATAAAGCATGCCATTTTTTAAATAACTTTATTGAGAGAAGAGGTTAATCCATATAGTTCATAT
TTTTATTTATTTATTTATTTTTTGCAAGATGGAGTCTTGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCGCAGTCTTGGCTCACTGCAACCTCCGCCTCCCCTGAGCCATTGCGCCCAGCC
CAGACTAGCTTTCTAAGGCCTATTTCAGCTCTGATCTTGTAATTTAAAGGAAATGAAGTTATTAGAGTCTGGATTAGTGGTGTATGTTTGGGAAGACCCAAAGGTGCTAGCTTGGCTAGC
ACCAAGTAATCTTTTTACAGGGATTAGAGTCTGATTATATAGGGATCAGTGAGCACTGATAACCAAGAGGTACCCTTTGCAGAAGGATGTGTGGGCAGTTAGCCTGGACAGATGACACAT
GGCTCAGCTGACACCTGCTGAGACTGCCCCCTTGTGGGAGATGAGGTTCAGCATTAAGAAGGAGGCAGCAGTGGCAAAGTAGGCCCTTTAACTGGACTTTCCTAGGAACCTACATATAGG
TTAGTCTCCTGAACCCAGGCTTTCATAACTCAGAAGCTTGCTTCTTCAGACTCTGTTGGTCTCTGCTGCTTCCCATCCCACTGGAACATGTACAGCCTCTTAAATAGGTACCATTTAAGA
GCCAATGAATGCCAAACACTTTTTTTTTTTGAGACAGAGTCTTGTTTTGTCGCCCAGACTGGAGTGCAGTGGTGTGATCTCAGCTCACTGCAGCCTCCACCTCCTGGGTTCAAGTGATTC
TCTTGCCTCAGCCTCCTGAGTAGCTAGGACTACAGGGGTCCACCACCACGCCCCACTATTTTTGTATAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCATGAACCCCGGAGGT
GGAGCTTGCAGTGAGCTGAGATCGCGCCACTGCACTCCAGCCTGGGCGACAATGTGAGACTGTCTCAAAAATTAGCCAGGTGTGGTGGTGGGCGCCTGTAATCCTAGCTATTTGGGAGGC
TGATGCAGGAGAATCGCTTGAACCCGGGAGACCGAGGTTGCAGTGAGACGGAGGTGGAGATTGCGCCACCGTACTCCAGCCTGGGCAACAGAGGGAGACTCCATCTCAAAAAAAAAAAAA
AAAAAAAAAAAAAAGAAAAATAAGAGATTAGTCCCCTTGCCTCATTTTCTTCAGGCTAGCCTGAGGCACATTCTTAGGCATTGTCAGGAAAAGGTTGAAGGCTGTGCTTTCTGTATAAAT
CTATGAAAAATTTCAAACTCTGCCTTTTGCTTACCAAGGGGTAGATGGCAGTTACTTAATGAAACAAGCGGGGGCTTCTGTTAAGTTCTTGATCCTTTATAAGGTTCAGGCTATCCAGTT
TGGTAGAGTTAGAAGAATGCTGAGAAGGCAGACTGAGTTTGCTGTCTTCAGAGCTCTGAAGGGCTGTCAGAAACAGTTTAGTGTTAAGGGTTTACATAGTCCTATGTGTGTCGTTTATTT
AGCTTTTTTTTCCCCTTAAGGATTAGAGAGTGTTGGCAAATTATTTAAACTTTGCCTTTTTTTGTGGAAAATTTAAATTTCAAGTGCTACATGAATAAATTAGGCATGATAGTATCTTAA
GGCTGTGGTGATGATTATATGTTTGTAAAATGGTTAGCTCATACTAAAAGGGTGAATGATCTAAGACTGATTGCAGGGGTAGGTTTCCTGGTATCTGAGTGTTCAGGTGCAGAACTGGTT
TTGTCCATAGGAGAATGGTGGTGCATACCATTGAGAAGGTTATTAATTAGTGGTGCCTTTCTCTTGCAGTGTGCCCAGCTGGCTGGAAACCTGGCAGTGATACCATCAAGCCTGATGTCC
AAAAGAGCAAAGAATATTTCTCCAAGCAGAAGTGA

Retrieve as FASTA  
CDS►
Send to BLAST
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
ATGTCTTCAGGAAATGCTAAAATTGGGCACCCTGCCCCCAACTTCAAAGCCACAGCTGTTATGCCAGATGGTCAGTTTAAAGATATCAGCCTGTCTGACTACAAAGGAAAATATGTTGTG
TTCTTCTTTTACCCTCTTGACTTCACCTTTGTGTGCCCCACGGAGATCATTGCTTTCAGTGATAGGGCAGAAGAATTTAAGAAACTCAACTGCCAAGTGATTGGTGCTTCTGTGGATTCT
CACTTCTGTCATCTAGCATGGGTCAATACACCTAAGAAACAAGGAGGACTGGGACCCATGAACATTCCTTTGGTATCAGACCCGAAGCGCACCATTGCTCAGGATTATGGGGTCTTAAAG
GCTGATGAAGGCATCTCGTTCAGGGGCCTTTTTATCATTGATGATAAGGGTATTCTTCGGCAGATCACTGTAAATGACCTCCCTGTTGGCCGCTCTGTGGATGAGACTTTGAGACTAGTT
CAGGCCTTCCAGTTCACTGACAAACATGGGGAAGTGTGCCCAGCTGGCTGGAAACCTGGCAGTGATACCATCAAGCCTGATGTCCAAAAGAGCAAAGAATATTTCTCCAAGCAGAAGTGA

Retrieve as FASTA