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Entry information : NmPrxGrx
Entry ID 4780
Creation 2007-03-03 (Nicolas Rouhier)
Last sequence changes 2007-03-03 (Nicolas Rouhier)
Sequence status complete
Reviewer Filippo Passardi
Last annotation changes 2008-05-09 (Christophe Dunand)
Peroxidase information: NmPrxGrx
Name NmPrxGrx
Class PrxII-glutoredoxin fusion    [Orthogroup: PrxGrx001]
Taxonomy Bacteria Proteobacteria Betaproteobacteria Neisseriaceae Neisseria
Organism Neisseria meningitidis    [TaxId: 487 ]
Cellular localisation N/D
Tissue type N/D
Inducer N/D
Repressor N/D
Best BLASTp hits
Perox score E-value NmPrxGrx
start..stop		 S start..stop
NgPrxGrx 499 0 1..245 1..245
VchPrxGrx 388 8.41e-139 6..244 9..247
ValPrxGrx 387 2.18e-138 6..243 5..242
AactPrxGrx 387 4.88e-138 3..244 12..253
Literature and cross-references NmPrxGrx
Literature REFERENCE 1

Parkhill J. et al.

Complete DNA sequence of a serogroup A strain of Neisseria meningitidis Z2491

Nature 404 (6777), 502-506 (2000)

REFERENCE 2

Rouhier N, Jacquot JP. Molecular and catalytic properties of a peroxiredoxin-glutaredoxin hybrid from Neisseria meningitidis.
FEBS Lett. 2003 Nov 6;554(1-2):149-53.
Protein ref. UniProtKB:   A1IRG1  Q7DDK4 [Other strain]
DNA ref. GenBank:   AL157959 (1089650..1090387)
mRNA ref. GenBank:   AAF41352  AAF41352 [Other strain]
Protein sequence: NmPrxGrx
Sequence Properties
first value : protein
second value (mature protein)
Length (aa):   %s   245 (837)
PWM (Da):   %s   26780.19 (94273.5) Transmb domain:   %s   i7-29o
PI (pH):   %s   4.47 (10.01) Peptide Signal:   %s   cut: 28 range:28-864
Sequence
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*.........1 .........2 .........3 .........4 .........5 .........6 .........7 .........8 .........9 .........0 .........1 .........2
MALQDRTGQK VPSVVFRTRV GDTWKDVSTD DLFKGKKVVV FSLPGAFTPT CSSSHLPRYN ELFGAFKENG VDAIYCVSVN DTFVMNAWAA EEESDNIYMI PDGNGEFTEG MGMLVGKEDL  GFGKRSWRYS MLVNDGVVEK MFIEPEEPGD PFKVSDADTM LQFVAPDWKA QESVAIFTKP GCQFCAKAKQ ALQDKGLSYE EIVLGKDATV TSVRAITGKM TAPQVFIGGK YIGGSEDLEA 
YLAKN 

Retrieve as FASTA  
Remarks Complete sequence from genomic. Hybrid protein with a N-terminal Prx II module and a C-terminal Grx module. Serogroup="A". Strain="Z2491". Identical sequence in serogroup="B"/strain="MC58" (SwissProt Q7DDK4, NCBI AAF41352).