The peroxidases and oxidases database
Entry information : HsLPO-B
Entry ID 5813
Creation 2007-09-21 (Marcel Zamocky)
Last sequence changes 2010-12-03 (Myriam Duval (Scipio))
Sequence status complete
Reviewer Christophe Dunand
Last annotation changes 2012-05-11 (Christophe Dunand)
Peroxidase information: HsLPO-B
Name HsLPO-B
Class Lactoperoxidase    [Orthogroup: LPO001]
Taxonomy Eukaryota Metazoa Chordata Mammalia Hominidae Homo
Organism Homo sapiens (human)    [TaxId: 9606 ]
Cellular localisation N/D
Tissue type N/D
Inducer N/D
Repressor N/D
Best BLASTp hits
Perox score E-value HsLPO-B
start..stop		 S start..stop
HsLPO 1272 0 18..629 101..712
HsLPO 50 0.000002 1..38 1..38
PtroLPO 1267 0 18..629 101..712
PtroLPO 50 0.000002 1..38 1..38
MmulLPO-B 1246 0 18..629 101..712
MmulLPO-B 47 0.00002 1..38 1..38
PpyLPO 1246 0 18..629 101..712
PpyLPO 48 0.00001 1..38 1..38
Gene structure Fichier Exons►
ExonStart..EndSize ExonStart..EndSize ExonStart..EndSize ExonStart..EndSize
N° 1 56320341..56320416 76 N° 2 56326421..56326538 118 N° 3 56326927..56327056 130 N° 4 56327776..56327982 207
N° 5 56329543..56329867 325 N° 6 56332172..56332332 161 N° 7 56342083..56342335 253 N° 8 56343514..56343687 174
N° 9 56344710..56344947 238 N° 10 56345148..56345355 208  
join(56320341..56320416,56326421..56326538,56326927..56327056,56327776..56327982 ,56329543..56329867,56332172..56332332,56342083..56342335,56343514..56343687,563 44710..56344947,56345148..56345355)


exon

Literature and cross-references HsLPO-B
Literature Conner,G.E., Fragoso,M.A. and Torbati,A. Regulation of lactoperoxidase expression. Unpublished in May 2007
Protein ref. GenBank:   ABQ53140.1
DNA ref. GenBank:   NC_000017.1 (56320341..56345355)
mRNA ref. GenBank:   EF579964 (1..2160)
EST ref. GenBank:   DC385493 [5' end]
Protein sequence: HsLPO-B
Sequence Properties
first value : protein
second value (mature protein)
Length (aa):   %s   629 (608)
PWM (Da):   %s   70824.87 (68616.5)  
PI (pH):   %s   7.59 (7.39) Peptide Signal:   %s   cut: 22 range:22-629
Sequence 932
Send to BLAST
Send to Peroxiscan
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
MRVLLHLPALLASLILLQAAASTTRDPSLDLTSLSLEVGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVCPTPPYKSLAREQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKPSPCEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVFTFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPWASVKN

Retrieve as FASTA  
Remarks Complete sequence from genomic (chromo 17, 9 introns). Lactoperoxidase splicing variant (prediction). Confirmed by ESTs. ESTs from the two variants are compiled in the same unigene.
DNA ►
Send to BLAST
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
ATGAGGGTCCTTCTCCATCTCCCAGCCCTCCTGGCTTCCCTCATCTTGCTTCAGGCTGCAGCATCTACCACAAGAGGTGAGTGTCTCCCTTTACGGGTTTTCTGGGGCTGCTGTCACAAA
GCACACCAACTGGATGGCCTAAGACAACAGAAATGTATTCTCTCACAGTACGGGAGGATAGAAGTCCAAAATCAAGGTGTTGGCAGGGCTGTGCTCCCTCTGAAGGCTCTAGGGAAGAAT
GCTTCCTTTCTTCTTCCAGCTTCTGGTGGCCCTGGTATCCTTGGTGTTCCCTGGCTTGTAGCTGCAACACTCCAATCTCTGCCTCAGTCTTTGCGTGGCCTTTTTCACTGGGTGTCCTCT
CCTCTTCTCATAAAACCACCATTTATTGGATTTAGGGCCGATGCTAAGGCAGTATGACCTCATTTTAATTCATAACATCTACAAAGACCCTACTTCCAAATAAGGTCACATTCTGAGGTT
CCATGCAGATGTGAATTTTGGGAGGGCCATTATTTAACCCACTACACTCTCCTTGTTGAGAAAACAGATCCTGTCCTCCATGCTCCAGACCCCAATACAAGAGGGAACAGGGAATCCCAC
CATTACTCTCATGCCATCCCCTTCTGTACGTCAGGGTCCTGGTGATCAGTGGGTCCTCTTTGATGAACTTGAGATAGTCCACAAGACCATCTCACCAGGAACCAGAGAAATCCCCACAGT
CCAGTAGCCCAAGCCACCCTGAGTGGCCACACTCCCTCTTCATCCCATCTCTGGGCATTCTAGTGAGATCTCAAAGAGCAATTTTGACATCTTGTTGAAGATCCAAGAGTATTCTTCCCA
TTCTGTGCTTTTTCCCCTTAAGGACTCTTATGAAACTTTCCTAATCTTGATCTCCTGCCTACCCAGATTTGAGGGGTGGGGGTAATGGCCGAGAAAGAGGGAGACAAAAGCAGAAGACAT
CGCAAAGGAGTGGTGTCTGACACCCTACTTCCTGCTCCCCACTCCAACCCCAAGCGCAGACTACCAGAACCTCTGCCATCTCCGATACTGTGAGTCAGGCCAAGGTCCAAGTCAACAAGG
CCTTCCTGGACTCCCGAACCAGGTACGTGAGACACACACACACACACACACACACACACACACACACACACACTTCCCTTCACAGGCTTCCTGTTCATGACAAGCACATCTAGGCCAGCC
CGGATGAGCCAATGAGGTGAACAATGATAAAACTTACCCTTCCATCCTCCTAGCCCTCCAAGTACATGACAAGTAGGAGCAATAGCCCACAATTCCTAAAGTCCTCAGCCTGTACATCAC
CTGAAAGAGGACATCTAATCTAACCCTAGAAGGACTTTCTTCCACGTGGCCCAATGTTTCCTTGGGCCATGCATTCCAGAGTCCCAGAAAGCCTCTCAGTAAAAGTTCTTCATTCATCCA
GCTGATATTGACTGATTCAGCCAGGTCCACCAGAAGCCGAATCCGAGCCCTGCATTCAGGTGCAGGTGACATATTAGGGGAATGCTCACAAGGAAGCTGTGATGGGGTGAAGAAGCAGAA
GTGAAGGGGGAGGTTAGACAAATAAAGTGGCTTCAAGTCTATCCTCAGCCTGACCCCACAGGGAGACCTGGAGCAGAAGTTGCTCCTCAGAGCCTGTCCCATCTTGGAGCGAGGGAGCAG
AGCCCTCATCTGCCCACATCAGTCAGACATGGCTGCAGGCTTGCAGGTGGCTGAGAGGTGTTGTGGCACACCTGTGGAATTCCCGGGCACCCCCAGCCAGGCCACTCCAGTGGCTCAGAA
GCAGGCGCCCAACAAGGTTACTGGAGTGAGCCTGTAGCAGATGCACCCATGGCAGCAAGGGGAAGAGCCCAGGGCCCACAGGGCACCAGTAGAGTCAACTGCCCTCCGATCCTGTACAGG
GGCAACGTGGGCGCCTTCCCTCAGGAAACGCACACTCTAGGGAGAGGGCAGACATTGAGAAAAAAAGTAACCTTATTCTTTCCTCTCGCTGTCCCTTTACACTGGACCTGGGCTTCCACT
CACTCCTCCTCAGCCCTTGAATGAACTTTCAAGCCGTCAGATAACTTTTTTGGTGACTTAGATGATAAAACACGCTCTGGACGCTTCTAGTCCCCAGACCAGGATTATCTCAGGAATTAA
AGTGTCAGCATAAGAAGATAAAGCCAGACCTGCTCTATTCCTTCAGCTCAGAACTGCTTGAGGCCTCTGGCGGGAGAAGAGAGTGCAGTCTCCTTCTCCCTCTTTCTGGGGCTCCTCCTT
CCCAGCTTGGGTTTCTGCTCCTTGGGGGTTAAGCTGAAGGAGGAGGGAAAAAGGGGTGGTGAGTCTACATCCCCTGAACAGTTCAGTCCTCAAGGGGCCGGAAGCTCTCTCTCTCTCTCT
CCCCTTGGGTGCTTTCCTGGTTTCAGAGAGAGATTCTGCTGCCAACTCTGTGATCTGGAAAATTCTCTGGCCAGTGGCTCCCAGCTCTAACCCTCTCTGCCTGGGAGCATCGGGCCCACT
CCTTCACCCCTCCCCACCCTGTCTTGGGGCAGGTCCCTTTTAAGCAGCCTCCAGAAGACTAGCAGCTTCGCCCTACTGTTGAGGCGGTGCAGATTCCAGATTCCGCCCCTCTCTCCGTGC
TCTCAGGACACTGCTCTTCAGGCAGGTGTCAAACCCCAGCCATGACTCCAGGACACACAGTTAAGCCCTCCTCCTAAGACCTTTCTCCCTAGAATTAAACTAGCAAAGGAGGAGCCCCAT
GGTGTTGGGAGGGACGTGCCCAGTATTTCTGCAAATGTCTCCAAAGGAAAATTCTCTCTCGCTCCTCAAATTCAATCCCTTTATAGCCTCAAGATGGGGGACAGCATAAAAGCCACAAAA
CCGGTGTTCATACACCTCCTTTGCAAGTCCTGCACAGGCCAACCAGCGCCCTGCTTTGAAATGTGGAGGAGCCCTTCCCTGCTGGTTAGTCCTTGGACTCAGGGGCCTCACAGAGACAGA
ACGAGTCACATTTAAACATTCTGTTACCCAAGTACATACACAGTGCAGTGACTCACAATTTATGATAAGGAAAATGAAGGAAATAAACAGGGCAAGGGATGCCACTCTAGGCACAGGGAT
CAGGGAAGCCTGTTGGAGAATAGGAAGGAGCCACCCAGGCAGAGGGCATGGGGGTGGCATTCCAGGCACTGCAACAGCATAGGGTCTGAGGCAGGAAAGACCGTGGGTGCTCAGGAAAAG
GAAGGCCAGTGGAGGCAGGAGGCAAGGAGGATCACGCATAAGGTGAGAGCAGAGAGGTGTGTCGCCCCAGGGTAAGCCATTAGAACATTTGAATCAGCGGTGGCATGGTCTGATTTTTAT
GCTAAAAAGATCACTCCAGCAGCCCTGTGGAGAACGAATGGGAAGAGGACAGCAGTGGAAGTAAGAGCTGTCTAGATGGGAGAGGATGATGGCTAGGACCGCGGTGGAGACTGTGGAGAT
GGCAAAGAGGTCCTTCCAAGACCCTGCCTACCCCCAACAGAGCCCAGCCCCAGGGCAGAGCAGGAGGTGAGTCCCTGGTGAATCTGTGTTCAGGCAGAGGAAGCATGCAGAGCCCAGGGC
CGGGCGGGAAAGGAAGGAACATCTGGAACCTTGGATGGGACCTTACAGGCTAAGCCCAGGGAGGCCCAGCGCGGCCTGCCTGCCTTTGTTCACGGTGTGAGGTGGGGACTCTAAAATACC
TTGCAGCAGCCCCTCTGGGACCCGGCTGATGGAGACAGTGATGCTCACACACGTGAGTGTGTGCTCTGTGCAGATGCAGCTCTGGGGGCCCTACATTCATTCCTCCCCAAAATCCTAGGA
AGTACTGAATCGAACTGTAGAAAACAGCTGTTTTCAAGGTCAAAAATGATGAAACAACATGGTTCAACCTAAGATTACCATCATTATTTTCATTATACCAATAAGGAAACTGAGTACAAA
GAGCTTAAGTAATTTGCCTCAAGGGCACACAACTAGAAAGTGGCAGTCAGGAGCCAATCCCAGTCAGTCTATCCCAAAGTCCATACAGAAGTCTCTGATGGGAGGAAATTGTGATTTCCA
GTTCATAAATGAGGGGAAGTCACTCAGAGGTCATATAATTAAACCAATCCTGGTGGAACCCAGATCCACCCCTGTGTCTGTCCAGCTCTAAGCCCACTTTAGGCTAGCAGTGTCCAAGAT
AACTTTCTAGGATGATGAAATGTTCTATATCTGCACTGTCCAACACAGTCATCACTAACCACACCTGGCTATTGAGCACTTGAGGTGTGCCTAGTGCTGCTGAGGAACTGAATTTTTAAT
TTTAATTTTAATGAGTTTCAATTTAAATAGCCACATGTGGTTAGTGGCTACTGTATTGGACAGTGCAGCAGCTGGGTTATGAGGCCATGTTGTACACACACCCCTCCCACCCCTCCAGCG
GCCCCCAGCCCCCTTCCTACAGGGTCCAGGCCATGATCCCCATCTCCCTCCACTGTAGGCTGAAGACCGCCATGAGCTCTGAGACTCCCACCAGCCGACAGCTCTCAGAATACCTCAAGC
ATGCCAAAGGCCGGACGCGCACAGCCATCCGCAATGGACAGGTGTGGGAGGAGTCTTTAAAGAGACTGAGGCAGAAGGCATCCTTGACCAATGTCACAGGTACAGAAAACCCACCAGCCC
TCTGTGGCAGGAAGGGGTCATCTCCCCACAGGAGAAAGCAGAGGCCACCCAAAGCTGCACTTCCTGTTGAGAGCTATCTACTCAGAGGAACACTCCTGTCTCTCCCTTCTTAGACCCGTA
GACGAGACTGGCAGAGCAAGGAAGGTCTTAGAGGACAGCTAGGGCAATGCTGTTTTTGCAGAGGAAGAAACTGAGACCTAGCAAGCTCACATGGCCGACTCCAAGTGAGGGGACATTGGT
GCTCTTTGTATAACACCGTCTGTAAGGCCTCTGCCCAAAGGAAGTGCTAAAGTCAATAAACATGGGTTCCTTGTCCTAAGCCACAGTGTCACCACTTCCTCTAGTAGAAGAGACATTTAA
GCCACATGTGTCAGGGGGATTTACTTGGGATAATGTCACAGGAGCTAAGATTTCCATCGTGTTCTGGGTAAGATGGAGCTATCAGTAAGTGAACTTAACTGATGGCTTGGTCATGGCCTC
CTCCATCCCCTCCACTCTCACCCCCAACCAAATGCCACAGCCCACAGAGGGTCATGAGGAAGGGGTTTGGTCCTGACAGGAGGAAAAGGCTGCAGGTTCTCCCTGGGAAAACATCAAGTG
AGGGGGGATACCTGGCCCAGGAGTTGGGCAAATTCCAAAGCTCCAAAAGAAGGAAACTGGGACAAGGTAAGAAGTAGGAAGCACTTTGACCTCTGAAATACAAAAGGTTCGGAGAGCTGA
AATCCTGCCACCTTTCAGAGATGGCCCCCCGGAAGAAGCCCCCATGAGCCAGATTCCCTCACCTCCCTGCCCTTGCAGACGCCAGGGTGGATGAGGGTATGCGTTCAGAAGTGGGCATCT
CTCTCCACTCTGTGCCCACACTGAACACTCTGATGCCTAAAGCCCCCCTACTCTGTCACTCCTCCCACAACCCTTGCCCCTCACTGAAAAATTACCTGTCCCTTCCCAACCTCTATCCTA
GCTATGTCCCTGCTTGCTTGGTACTTCAGATGTGAACGAAGCTTTAGAAGAAAGCAGTCTTATCACACTAACTCATACTAACATATGCTTAACCTCCCGGGGTATTTCCATTCTAAAAGA
AAGATCTGTCAATTCAAATGAATCTGGACCTGGTATACCAGGAATTACTAGCAATTCTGGGGACATTCCCAGTTACTCTGTGTGGCCTTGGGCAAGTCTCTTGAACATTGTGTTCTCATT
TTCTTCCCTGTAAAATGGGAATAAAATGTATTACCTTAATGTGCTGTCAGATTAATTGAGAAACCACTTGAGAAACGCTTACTTAGAATGGAATGCATTCCAAAACATGCAGGTTCACCT
CTGGTCTCCATTTCCTGCCTCCCACGGGTGCCTGTGAATGGAGAAAGAACTCAGTCCCTTTGGGGTCCCTTCTGTTTCAGATCCCAGCCTGGACTTGACTTCACTGTCTCTGGAGGTGGG
CTGTGGTGCTCCTGCTCCCGTGGTGAGATGCGACCCGTGCAGCCCTTACCGCACCATTACGGGAGACTGCAATAACAGGTGGCGGGGCTTGGGGTGTGGGGGCCGACCATTCCAGCCACT
CCGCCCCGCCCTGCCAAGGCCTTTGTCCCTTGGGCACTCTAGGCAGATCTGCCACTGCCTTGCCCACCTGGGCTGGCGTTCCCACCTTCCCCACCTTCTCAAGATCGCGCGTCTCCAGCC
CTCTCCCTCCAGCCCACTGTGTGTCTCTGGAAGCGGCACCTTTCCCCGGGGCGGGGGAGCCCCGCGCCTTCAGGGGGTGGGCGCAGTTCAGAGACCCCAAATTTGAGAGGCCCCCTTCTC
TGCGTCCCCTCCGCCTCGAGCAGAGGCTCCTTCCCCCATGGGGTCCTGGGCTTTGGAGCCCCGGAGCCGGCCTGCCGAAGCTCAGCGAGGATCGTGCTGGTTTCAGGAGGAAGCCTGCGC
TGGGCGCCGCCAACAGGGCTCTGGCGCGCTGGCTGCCCGCGGAGTACGAGGACGGGCTCTCCCTGCCCTTCGGCTGGACGCCGGGGAAGACGCGCAACGGCTTCCCTCTCCCGCTGGTGA
GGGCAGGCCGGGCCGGGGTGAAGGATGGGAGCCAGAGGGGACGGGATGCACTACCCAAACACGCAGTGAAAGGAGGAGGAGGGATCGGTGGGGGCAGCAGGGGTGCGCGATGGAGATCTG
CACAGACCCCCACCTTCCGCTAGAGGGCAGCAGAGCTCGGAGCCCGGAGCCCGGCCACGTGGCGGTCACGTTCTGGCCGCCGCAGGCCAGATACCCTGGGGTCTCCCGGGCAGATGGCCT
CCCTGCCCCATCCCGCTCGCACTTACCCCAGCCCCCGCCCCTGGAGTGCATCAGCTGTTGTTTGCCTGGAGGTCCTATTTGTTGGCCTTATCGAGCTGGCAGCCCCTACCCAGAGCCCCT
CTCCTATTCCTGGACACCTGGCACCTCCGTAGCTCGCATTTCAGAGGCAGCCTGTCTTTGTTTTCCCTCTCTTAGTGGAAAGGGCACCGGCTTGGCAAATCATCAAGTCATACGGATCTG
GGTTCAATCCCATCCCTGTCCCTTTGTAGCGGCAGGACCTTGGAGAACTGACTTCACCTGTCCAGGATTCAATCTCCCCCTCTACAGAATAGGCTAATGCCACCCACCTCACAAACTCCT
TGTAGGGATTAAGTGCACTTGTAACATGGTAGGTAGTTAATAAGCTGTAGTTGCATCTGAATCCTCAAAGCACTTTTTCCTCTAATCTGCCCTCCCCTTCTCTCTCCATCTGTAGGCCCG
GGAGGTATCTAACAAGATTGTTGGCTATCTGAATGAGGAGGGTGTTCTGGACCAAAACAGGTCCCTGCTCTTCATGCAGTGGGGTCAGATTGTGGATCATGACCTGGACTTTGCCCCTGA
CACCGAGCTGGGGAGTAGCGAGTACTCCAAAGCCCAGTGTGATGAGTACTGTATCCAGGGAGACAACTGCTTCCCCATCATGGTACGGCCCTGCAGCTAGGCATCTCTGACTAGCCCCTT
GCCCACCCTGATGTAGCAGACATTCCCAGCTCATCAGCTAGGATCTCTGGATAGATCTGGGATACTGATTTGGTAGTTTCCCATGCCTCACGTGTCCATTCGTTCACTCATCCGTTTATT
CAGTAAATAGACATTGACCACCCCATACCAGGCAGTGCACTAAGCGCTGAGGATTCCAAAGTGAACAGGACACCGCTCCTGCTCTCAAGAACAAAGGGCCAGTGTGGGAATTGGACAAGT
AAACTACTGATAGCAGAATGGGAACACTGGAGAAGGTTGTCTACATTCCCGACCCAGCAGCATTGGTAAAACCTGCTTATTAGAAATGTAAAATCTCAGTTGGGCGAGGCGGCTCATGCC
TATAATCCCAGCACTTGGGGAGGCTGAGGTGGACAGATCACCTGAGGTCAAGAGTTTGAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCTGGC
GAGGTGGCACATGCATGTGGTCCCAGCTACTCAGGAGGTTGAGGCAGGAGAACCGCTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCCGAGATCACGCCACTGCACTCCAGCCTGGGCAA
CAGAGCAAGATTCCAACTCAAAAAAGAAAAAAGAAAAAGAAAAAAAAAATGCAAAATCTCAAGTCTCACCCAAGATGTTAGGAAATAGATTCTACATTTTTACCAAGATCAACAGAGATT
CATTTTATACATGATAAAGTTTATACTGCTGTACATCATCGTGGAGGATGACTTCAACTCCACTCAGAAGGACTTGAAACCTGGATGAATCCGAGTGAGCAGCAGGGATTTGTAGGGATT
TCCATCCGGAAGGGAGAGGAGCTTGCAGCAATGCATCTTTTCTTATTATTCATGGGTATTACAGTTGGAGAGTCATTTCTTCACTCAAAGAATAAATCGAGGCTATGTGCTGTGGTATAA
AGAGCATAAACTGTGGAATGAAGCCAATGATCTGAATCCTACATCTTTCCCTTCCAGTGTATAAGTTCTTAGGCAACTTACTTAACTTTTCTGAGCCCCAGTTTTCTCATCTATAAAATG
GAACTGAATTGTCCACCTTACAGGGTTTTTTTGAGGACTGAGATGAGTTAAAGTATGCATAATTCCTGGCACATGGTAAGTCCAAAATAAATACATGGCAGCTGTTGTTAGTAGTAATTA
TTAACAAACCTGTTCCCACCTCGTGTCCTGCTTTCCTGTCCAGGGAGCTCAATACTCCCTCCTCACCAGAAATTTGGAGCCCTCACTGTGAGGACTGAATGATTACCCTCAGTTCTTTCA
CACAACAGGATGTAATGAACTTCAGGATATTATGAGCCCAGGGTGTGTAATGTCAGCAAGAAGTGTCTGGGGTCAGTGTCTGGTACCAGGGTCCTAGGAGGGTGCCATCAGCATCTTTGC
ATCCAGACTTGCCCTGGGGAGAGGTTGCCAGGACCCAGCTGTTCCACCCCTGCCCAGTCACTTATGCCCACTCTCTCTGCAGTTCCCACCCAATGACCCCAAGGCGGGGACTCAAGGGAA
ATGCATGCCTTTCTTCCGAGCTGGGTTCGTCTGCCCCACTCCACCCTACAAGTCCCTGGCCCGAGAGCAGATCAACGCTCTGACCTCCTTCCTGGATGCCAGCTTTGTGTACAGCTCCGA
GCCAAGCCTGGCCAGCCGCCTCCGCAACCTCAGCAGCCCCCTGGGCCTCATGGCTGTCAACCAGGAGGTCTCAGACCATGGACTACCCTACCTGCCCTATGACAGCAAGAAGCCAAGCCC
CTGTGAGTTCATCAACACCACTGCCCGTGTGCCCTGCTTCCTGGCAGGTGAGTCTAGCCTGGGAACAGAAGGGCCCAAGGACAAGGGGATTATCCAGGGAAGCTTTACCACTGCCCCCTT
CTTGTCATCTTTCTGGAAAAATGCACACTGAGCCATTGCTGTCCCTAGCAGTGGTCCAGGACTAGCAGAAGGGCCCAGATGAATAAAGAATTCCAGAACATATGTTCACTGTAAAACAAA
ATCAGGAAGTCCAGAAAAGTAACAAAGAAAATAAAAAGAAAGTGCCAGGCTTGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCAGATCATGAGGTCACGAGATC
GAGACCATCCTGGCTAACATGGTGAAACCCCGTCTCTTCTAAAAACACAAAAAATTAGCCGGGCGTGGTGGCACACCCCTGTAGTCCCAGCTACTCTGGAGGCTGAGGTAGAAGAATCAC
CTGAACCCAGGAGGCGGAGGTTGCAGTGAGCCGAGATCACGCCACTGCACTCCAGCCTGGGCAACAAAGCAAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAAAAAAAGAAAGAAAGAA
AGAAAAGAAAAGAAAAAGAAAATTCACACAATCCCACTACCCACCAATAATCATCGTTAACATTTTCATGCTTATTTTCCAGTATTTTTTCTATCACAGATACAGTTCTACATTGTTTTA
CATAATCGGGTCTTACTATAAATAATGCTCCAAAACCTGATGTCTTCACTTAATTTACTCCATGCCATTAACTGTTCTTCTATGACGTGATTTTTAATGGCTGCCTGGTATTTCATGACA
CATATTACCATCATTTATTTTCTCAATCCTACTTGGGGGAATTTAGTTATTTCAAGTTTTCCTGTGTTTTGTTGCTGTTGTTTAGGTAATGAACATCTTCATTGATAAATCTTTGTTCTC
ATTTTTAATACATTTATTAAGCTAATTTCCCAGAAGAGGAAGTTCTAGATGAAGAGGAATGTATATTTTTAAAGCTTTTTATAACCTGGGGACAAAATCCCCATTCCATTCAGCCTGTGC
ACGACCAAAGCCCTGCTAATTCTGTTCATTCCAGGTGCCCTCCTGGTCCTCTCTGTCTCCGGCTTCTAGAGGCCATCCCACCCTCAAACATCCTCTCTCTTTGGACAAACCCCCTGGCCA
CCCTGACATTGCAGAAGGCCAGCTCTTAGGCCAAGATACCTTTATAGATCTTTTGGATTTTGTGTTCACATATATCCCACAGCAATCCAGACACAAAACCGAGTTCTTTCTTGTTTTTCA
TAAAAATATGCACTCACACCAAGAATTTACAATTTTAAATAGATTTCCTGGCCTGGTGCAGTGGCTCATGCCTGTAATCCCAACACTTTGGGAGGCTTAGGTGGGAGGATTGCTTGAGGC
CACAAGTTCGAGAACAGCCTGGGCAACATAGCAAGACCCCTGTCTCTACAAAAAATTTAAAAACTAGCAACACATGGTGGCACATGCCTGTAGTCCCAGCTACTCTGGAGGCTGAAACAG
GAGGATCACTTGAGCCCACGAGGTTGAGGCTTCAGTTAGCCAAGATAATGCCATTGCACTCCAGCCTGGGCAACAGAGCAAGACTGTCCAGATAGATAGATAGATGATGATAGATATATA
GATATATAGATATATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGACTCTCCTAAAGATTAGAGGGCACAGGGAGAAGTCCTTTATCCCCTTATGAGACACCTGGTCTTTGG
CCATTTAACTGTTCCCCCATCGTTACTCCTCTCTCCCTCCCACTACAGACCCCCATCTCCAGATTATTCTCCCTTTATTACCCAGAGGAACTCAGCCTTACCCAAGCTCCTCACCTCAAA
CCCGCATTCCTAAAACCTTCAAATTTGCTCTGTGAAGTAAAAAGCTCCTCATTCATTCGAAGCTCCCCTTCCTAGAAGGCGGTTGGGTTATAATTAGCAAAATGTTACTGTGTAGTTTGT
CACCACTAGCCTTTGTCACAGTGCTGTGATAGGCTTTATTCTCATTTTCATAGGTAAGGAGACCGAGGCTCAGAAGTGTTAAGTAACTTGTCCAAGGTCACACAGCTAAAAAGTGTGTAT
ATAGAACTGAGAGTCAAACCTATGATTCAGTACCCCCTCCCCATCCCTATTCACCTGACGGGAAGTAGGGCTTGTTGACGGGGCGGGGGGGGCGGGGCGCGGTCCTGTGGGGCACCATCA
TTTCTTTGTGCAGGTTACTGGGTCCTGGGGCTGTTAGGGAGAATCTACCTTCCTGCCTTCTGGGCTTTCAGGAGATTCTCGAGCCTCAGAGCATATTCTGCTGGCCACATCCCACACCCT
CTTTCTCCGCGAGCATAACCGGCTGGCCAGAGAACTAAAGAGACTCAACCCTCAGTGGGATGGAGAGAAGCTCTACCAGGAAGCCCGGAAAATCCTGGGAGCCTTCGTGCAGGTAGGGAG
TCCCAGGAGCACTGTCACCTGGTCCCACCTGGCTCCCACTCCTGGCTCTGCCCTCTGCTGGCTGCTGTGCCTCAGGCTCTCTCCTCTGTTCCCACACCTCCGTTTCCCCCGGCCCCTCTG
CTGCTTCTCTCTTGTTGTCTCATTCTTTGAAATCCCCTTCCTTTCATTTCTTCAGCTTCTCTGTCTCAAAATGAATCTCTGGATTTGGAGTGTTGGAAAGTCACTTGTGCGTTGGTCCCT
TCAGTGTGCCTGCCTGGGTGCCATTACTGGGACTGTAGGCTCCTTCACTCCCGGGACTGCTACATCGCAGTGATTTGGGTTATTTTGATTTGATTCTCTTCCTTTTTAATTGTCTACATC
TACGCCCATCTCATGGGCATACTCAGCGGATACTGTTGATTGGCTGATCAACTAACTAGAAGAGATTTACAAAGGTTGATGTGTTGATATTAACCATGCACATATTTTTTAAACATTTTA
TTTTGAAATAATTATAGATTCTAATATATTGCAATAGGAGGGGGGTTTCAAAGGATGAGACAACAGGAGAGAAGCAGCAGAGAGGCCGGGGGAAGCAGAGGTTTGGGAACAGAGAAGGTA
GCTGGAGGCGCAGCACCGAGCAGAGGGCAGAGCCAGGAGTGGGAGCCAGGCGGGCCCCAGTGGCAGGGCTCTTGGGCCTCCCTCCCTGCAGATTATTAGATTCTAAGAATTGTACAGGAA
ATTTTTAAAAATGTACAAGGAGGTCCCATGCACCCCTCACCCAGTCTCCTCCTTACATTAGCATGTAAGTGCTAATGTCTTACATAACCAAGATACACTGGCAAAACCAGGAAGTTAACA
ATGATATAAACCATAGAGCTTACTCAGATCTCACCAGTTATAAATGCAATCAACTGTGTGTGTGTATGTGTCTGCATAGCTCTATGCAGTTTTATCACAGATGTAGCTTCAAGTACTACC
ACAATAAAGACTCTTAACCGTACTGTCCCCTAAAACTCCCTCATGCTATCTCTTCATAGCCACATCCACCCTCACCCCTATATCCCTAACCCCTGACAAGCCCTGATCAGTTCTCCATCT
CTATGTTATTTCACAGATGTTATATACATGGAATTATGCAACATGTATCCGAGATGGGCTTTTTTCATTAAGCATAATATCTTTGAGGCTCATCCATGCTGTTGTGTATATAAATATTTC
ATTCCTTTTTGTTGCTGAGTAGTATTCCATGGTATGAATGAACTACAATTTGTTTAACCATTCAACTTTTGAAGGGCATTTGGATAGTTTCCAGTTTTAGATTATTATGAATAAAGCTAC
TACAATCATTCAAACATAAGTTTCTGCATGAAAAGAAATGTTTATTTGTTTGAGATACATGCCTAAGAGTGCAATTGCTAGGTCACATGGTAAGTCCATTTTTAGGTGTTTTTTTTTTTT
TTAATTTTTTAATTTTGTGGGTACATAGTAGGCGCCTATATGTATGGGGTACATTAGATGGCTTGATAAGGGCATACAATGTGAAATAAGCACATCGTGAAGAATGAGGTATCCTGCTGG
GCACAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGAGCAGATCATAAGGTCAAGAGATCGAGACCATCCCGGCCAACATGGTGAAACCTTGTCTCTACTAAAAATAC
AAAAATTAGCTGGGTGTGGTGGCATGCGCCTGTAGTCCCAGCTACTCGGGAGGATGAGGCAGGAGAATCGCTTGAACCCAGGAGGTGGAGGTAGGAGGCGGAGGTTGCAGTGAGCCAGGA
TCACACCACTGCACTCCAGCCTGGGCAACAGAGTGAGACTCCCTTTCAAAAAAAAAAAAAAAAAGAATGAGGTATCCATCCTCTCAAGCATTTATACATTGAGTTGCAAACAATCCAGTT
ACACTCTTAAGTTATTTGAAAATGCACAATTAAGTTAAATTATTATTAACTATAGTCACCCTGTTGTGCTATCAAATAGTAGGTCTTACTCTTTTTTTTTTTTTTTTTTTTTTTTTGAGA
TAGAGTCTTGCTCTGTTGCCCAGGCTTCCTCAGCCTCCTGAGTAGCTGGGGTTTCAGGCACCTGCCACCACGTCCTGCTGATTTTTGTATTTTTAGTAGAGATAGGGTTTCACCGTGTTG
GCCAGGCTGGTCTCAAACTCCTGACCTTAAGCGGTCCACCCACCTTGGCCTCCCAAAATGCTGAGATTACAGACATGAGCCACCGCGCCTGGCCATCATTCTATTTTTTGGTACCCACCA
ACCATCTCCACCTCCGCCCCCCACAGCCCCTCATTACCCTTCCAGGGATCTGGTAACCATCTTTCTACTTTCTATGTCCATGAGTTCAATTGTTTTGATATTTAAATCCCACAAATAAGT
GAGAACATGCCATGTTTGTCTTTCTCTGCCTGGCATATTTCACGTAACATAATGATTTCCACTTCCATCCATGTTGTTACAATTGACTAGATTTCATTCTTTTTTATGGCTGAATAGTAC
ACCATTGTGTATATGTATCACATTTTCTTTATCCATTCATCTGTTGATGGACACAAGTTGCTTTCAAATCTTAGCTATTGTAAACAGTGCTGTAACAAATGTAAGAGTGCGGATATCTCT
TTGATATACTGATTTTATTTCTTTTGGGTATACACCCAGTAGTGAGATTGCTGGATCATATGGCAGCTCAATTTTTAGTTTTCTGAGGAATCTCCAAACTGTTCTCCATAGTGGTTGTAC
TAATTTACATTCCTGCCAACAGTGCCAAATGTGTTCTCCACATTCTTGCCAGCATTTGTTATTGCCTGTCTTTTTTATATAAGTTATTTTAACTGGGGTGACATAATATCTCATTGTAGT
TTTGATCTGCATTTCTCTGATGATCAATGATGTTGAGCACCTTTTCATATGCCTGTTTGCCATTTGTATGTCTTCTTTTGAGAAATGTCTATTCAAATCTTTTGCCTATCTTTTGATTGG
ATTATTAGATTTTTTTCCTATAGAGTTGTTTAAGCTTCATATATATTCTGGTTGTTAATCCCTTGTCAGAAGGGTAGTTTGCAAAATTAATATTTTCTCCCATTCCGTGGGTTATCTCTT
CACTTTGTTGATTGTATCCTTTGTTGTGCAGAAGCTTTTTAATTTGATGTGATCCCATTTGTCCATTTTTGCTTTGGTGGCCTATGCTTGTGGGATAGTGCTCAAGACATTTTTGCCCAG
ACCAATGTCCTGGAGATTTTCCCCAATGTTTTCTTGCAGTAGTTTCACAGTTTGAGGTCTTAGATTTGTCTTTAATCCATTTTGATTTGATTTTTATATATGGGTAAAAGATAGGGGTCT
AGTTTTATTCTCCGGCATATGGATATCCAGTTTTCCCAGCACCATTTATTGAAGAGACTGTCTTTTCCCCAGTATATGTTCTTGGCATCTTTGTTGAAAACGAGTTAACTGTAGATGTGT
GGATTTGTTTCTGGGTTCTCTATTCTGTTACATTGGTCTTTGTGTCTGTTTCTATGCCAGTACCATGCTGTTTGGTTGCTATAGCTCTGTACTATAACTTGAAGTCAGGTAATGTGATTC
TTCTGGTTTTGTTCTTTTTGCTTAGGATAACTTTGGCTACTCTGAGTCTTCTACTTTTAGTTTTAAAAGGAACTGCCAAACTATTTTTTAGAATGGCTGTACCATTTACATTCCTATCAG
CAATGTATGCATGATCCAATTTCTTAGCATCCTGACGGTGTCACCACCATTTTTTGTTTTATCCTTTCTGATAGGTGTGTAGTAATAGCTCATTGTTTTAATTTGCATTTCTCTAATGGC
TGGTAATGTTGAACATCTTTTCCTGTGCTCATTTGCCACTTGTGCATCCTCTTCAATAAAATACTTGTTCATATATTTTGCCTATTTTCAAATTGGACTATTTGACTTGTAATGTTGAGT
TTTGAGAGTTCTTTACGTATTCTAGACACAAGTCCTTTGTCAGATATGTGATTTGCAGTGATTTTCTCCCAGTCTATAATTTGGTGGGGGTTTTTTTTTTCATCCTCTTAAGAAGGTCTT
TTGTAGAGCAAAAGCTTTTAATTTTAATGAAGTTCTTTTAATCAAATTTTCCTTTCCTGGATTGTGCATGTGATGTCAAGTCTCAGAACTTTTTTCCTAGTCCTAGGTCCCAAAGACTTT
CTCCTGCTTTTTCCTTCTAGAAGTTTTATAGTTTTATGTTTTACATTTAAGTCTATGATCCATTTTGGGTAAATTTTTGCATAAAGTGTGAGGTTTAGGTCAAGATGCTTTTTTAAATTT
TTTCTGGCTATGGATGTCAAATTGCTCCAGCACCACTTATTGAAAGGCTATTGTTTCTCCATTGAATTGCTTTTGTTTCTTTGGTAAAAAATATTTGGGCATATTTACATGGATCTATTT
CTGGGTTGTCTATTCTCTTCCATTGGTTTGTATGTATGTCTATTCCTCTCATACCACAGTGCTCAATTACTATAGCTATACAGTAAGCCTTAAAACACTTTATTCTTCTTTTTCAAAATT
GTTTTGGATATTCTAGGATCTTTCCCTTTCCATACATATTATTAAATAAGTTTGTGTATGTCTATCAAAAAACCTTATGGAAATTTTGATAGAAATTGCATTAAAATTATATATACATTT
AGGGAGAGTTGACATCTTTACAATGTTGAGTTTTCCAATCCATAAACTAAGTATGTCTCCCCAATCTTTAGATTTTTTATTTCTTTAATCAACATTTTGTAGTTTTATCACACAGATTCT
GTACATGTTTTGTTAGATTTATACCTCAGTATTTAATTTTCATTTTGTTTTGTTTTGTTTTGAGACGGAGTCTTGCTCTGTCACCAGGCTGGAGTGCAGTGGCACGATCTCGGCTCACTG
CAACCTCCCGGGTTCAAGTGATTCTCCTGCCTCAGTCTCCTGAGTAGCTGGGATTACAGGCGCCCGCCACCATGCCCGGCTAATTTCTGTATTTTAGTAGAGACAGAGTTTCACCATGTT
GGCCAGAATGGTCTCAATCTCTTGACCTCGTGATCCGCCCACCTCAGCCTCCTGAAGTGCTGGGATTACAGGCGTGAGCCACCATGCCCAGCCCAGTATTTCATTTTCTTTGGAGGAATT
ATAAATGGTATTACAGCTTTATTGCAGTTTCTACTTATTTTATCAGTGTATGAAAATATAATTGATTTTTTTATGTGTTGATTTTGTATCCTGTGACCTTGCTAAATTCAATTAGTTCTA
GGCATTCTGCTGTAGATTACTTGGATTTTCTAAACAGGTAATCATGTAATATGCCAATAAAGACAGTTGTGTTTCTTCTTTTCTAATCCATATGATTTTTCTTTCTTTTTCTTGCCTTAT
TACGTGGCAATTCCTGGAACTTCCTAGTGGCTCAAACTTCCAATACTATATTAAATGCGCATGGTAAGAAAGCAGGCATCCTTGTCTTCCCAATCGAGAAAGTATTCAATCTTTCACCAT
TAAGTATAAGATTAGTTATAAATGTTTTGTAGTTGCCCTTTATGAGGTTGAGGAAGTTCTGCTTCATTCCTAGTGTAATGAGAGTTTTTATCATGAACAGGTGTAGAACTTTGTCAAACG
GTTTTTCTGCATCAATTGATAGGATCATATGATTTTTATCCTTTAAACTATACTGCTTGCTTTGGATTTATTTTGCTCTTATTTTTCAAGTTTCTTGAAGTAGAAACTTAGATGACTGAT
TTGCAATCTTTTCTATTTTCTAATGTATTTAGTACTATAAATTTCCCTCTTAGCACTGAGTTGACTGCCTCCCACAAATTTTGATATATTGTGTTTTTATTTTCATTCAGTAGGTATTTT
TTAAGTTTCCTTTCGGACTTCATCTTTAACCTATGTATAATTTAGAAGAGTGTTATTTAATTTCCAAGCGTTTGTAGATTTTCCTGTTGCCTTCCTGATTTCTAGTTTGATTCCATCATG
ATCAGAAACTATACTCTGTATGATTTCAATTTTAAATTTGTTAAGATTTGTTTTATAACCCTGCTGTGGACTATCTTGTTGAATATTCTGTGAGTTCCTAAAAAGAATGTGTATTCTGCT
GTTGTTGAATGCAATGTTCTGTAAATGTCAGTTGGATCTGTTGGTTGATGGTGCTATTCAGTCTGTACTCCAGCTAATTTTCTGTCTAGTAATTCTCCCACTTACTGAGAGTCAGGTGTT
GAAATCCCTAGCTATAAATGAGAATTTGCCTATTTCTTCTTCCAGTCCTGTCAGGTTTTGCTTCATGTATTTTAAAGCTTTAAAGTTCTGTTGTTTGATCCATATCATTTAGGATTGCTT
CATCTTCTTGATGGATAGATCCTTTTATCATTATGTAATTTCCACTTTTGTCCTCTGAAGTCAACTTTATCTGATATTAATATAGTCACCCCTGCTTTTAAAAATTTATGTCTGCATGAT
CTTTCTTATTCCATCAATTTCAACCTACCTATGTCATTATGTTTGAAGCGAGTTTCTTTTAGACATCATATAGTTGGGTCACTTAAAAAAAAAAAGGAAAAGAAATATACTCTGCCAATC
TCTGACCTTTAGTAATTAGTACTTTTAAATTATCTTTAAAATAATTATTAACATGTTAGGGATTAAATCTCCCATATCTCTCATTTTATTACTTGTTTTCTGTTTGTTCCTTCTGTTTCT
TCTTCCTCTAATATTGTTTTTCTTGCCTTCCTGTGGGTTAATTGAACATTTTTTAGAGGTCCATTTGATCACATATTGCTTTGTATAATTTTCTTAGTGGTTGTTCTCCGGATAGATAGG
TAGATAGATATAGAAATAAAGATAGAGAGAGAGATAGAGATATGGATTTACAACGTATCACAACCTATTGGTGTCAGTGCTTTATCATTTCAAGTGACATGTAGAAAACTCATTTCCATT
TGGTCCCTTCACCTTCCCCACTTTTGAAATATAATTGTCTGAAGCATTTCTTCTATATATGTTTTATAGCACATCAGATGGTGCTTCAACCATAAAATATAATGAAAAAATTCATGAGGT
GGAAAAGAATTGATGTTTACTTCTATTTTTACCCATTACATTGTTCTTCTTTCCTTTCTGAAGGTCCTGTCCTTCTTCTATTACCATTCTTCATGTTTAGAGAGTTTCCTTTAGCCATTG
TTTAAGGATAGGTCTGTGTGCAGCAAATTCTCTGAGTCTTCCTTTGTGTGAGAATGTCTTTATTTCTCCTTTATTCCTGAAGAATCGTTCCACCAGCTATTGGATTCAGGGTTGGTAGTT
CTTGTCTTTCGGCACATGAAAAATGTGGCGACACTTCCCCTGGCTTCTGTGGTTTCAGATGAGAGCTTCACCGATATTTTGTTTGTTTGTTTATTTCTTTGTTTCTTTGAGACAGAGTCT
TGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCAACATCTCGACTCACGGCAACCTCCGCCTCCCGGGCTCAAGCGATTCTCTTGCCTCAGCCTCCCGAGTAGCTGGGATTACCGATGCTCA
CCACCACACCTGGATAATTCTTTTTGTATTTTTAGTAGAGACAGGATTTCACCATGTTGGCCAGGCTAGTCTCAAACTCCTGACCTCAGATGATCCACCCGCCTCAGCCTCCCAAAGTGC
TGGGATTGCAGGCGTGAGCCACCACACCCAGCCCTTTACCATTACTTGAATTGGTGTTTCTTTATAGGTAATGTGTCATTTCTCTTTGACTATTTTAATACTTTATGTTTAGTTTTCAGA
AATTTAATTATGATATGCCTTGGAGTGAATTTCGCTGTTTATCCTGTTTGGGATTCATTCATCTTCTTGAATCTGTAAATGTGTGCCTCTCACCAATTTTGAGAAATTTTCAGGCATTAT
TTATTCAAATCCTTTTTCAGTTTCACCCCCTTTCTCCTCTGTTTCTGGAACTCCATTGATATGAATGCCAGATCTTTTGTTATGGTCTCACAGAACCCAGAGGCTCTGGTTTGTTTGAGC
AATTTTTAAAGTCTATTTTCTTTCTGTTGTTCAGATTGAGTAAATTCTATTGATCTGTCTCCAATTCTATCCTCTGTCACTCCCACTCTGTTATTGAGTCTATTCAAGCTTTTTTAAAAT
TTCAGCTAGTGTATTTTCAGTTCTGTAATTTTGATTTGTTTCTTTTTTATAATTTCTACTTCTTTGCTATGATACTGTATTTGTTTCAGGAGAATCTGTAATTGATTATTGAAGCATTTT
TATAATGGCTGCTTTTAAAATTTTTATCAGATAATTATAGCATCTGATTCATGTCATCCTTGGCATCAGTTGATTGTCTGTTTACTCAAAACGTGGCATTTCTGGCTCTTGGTATTATGA
GTGATTTTCAGTTGTATCTTAGACATTTTGGTTGCTATATTAGGAGACCCTTGATCCTATTTAAATTTTCTATTTTAGGCCAGGCACAGTGGCTCACGCCTGTAATTCCAGCAATTTGGG
AGGCCGAGGCGGGTGGATCACCTGAGGTCGGGAGTTCAAGACCAGCTTGGCTAACATGGTGAAACCCCATCTCTACTAAAAATAGAAAAACTAGCCGGGCTTGGTGGCATGCACCTGTGG
TCTCAGCTACTTGGGGGTGCTGAGGCAAGAGGATCACTTAAATCAGGGAGGTCAAGGCTACAGTGAGCCAAGATGGCATCACTGCATTCCAGCCTGGGTGACAAAGTGAGACCCTGTCAA
AAAAAAAAAGCACTTCATTTTAGCACATAGTTACCTTGTTTAGGTTTAGCATGTAGGTTCTGGACTACTTTTGTGGGCTTTAGGTCCACCAAAGCTTAGTTTCCTGAGCCTTGCAATGCT
ATTCTGGTCTACTTCACTCTTCTGGTGTTTGGGGGCTTCCCACTCAATCCCTGCTGGTGCTGTCTGCAAGGCAGGAAAGTACTTCCCTGGCTGCCTGCTGTTGCTGAGCAACCTTCTAGG
GGAACAGGAACCACTGCACCTGAGCTCCTTATGGCACTGGGTTAAGAGCAAAGAGACACAGAGCCTCACTGTGAAAGCTAGATAGAAATGTGGAAAATGTGAAGCAAAAAAGCAGAATGC
ACAGGTATGCATTCTGTAGGATTATAACTATGTAAAAGTCGGTAACATATAGACAAAGACTACAAGAATAAAAATTAATATAATTATTAGGTTATGTGGAGGCATTTTTCTTTTCTGAAA
ATTTTTTATTTGTGTTAGTTCATTGTGTTTTTATGTAAAAGAAAACCAGAAACCAGTCTTTCCATTCTTCTGTATTTCTTTCAGAACTGGAGATTGGATGAACTTTCCTCAGTTGCCCCT
GAATCATTCCTGTGGTTTATCATTCCTCTTGCCCTGACATTGTTACATTAAAGTGACACACAAAGACTGTCACTTTAGCATCAAGGTCATAAACTTAGCACAAAGATGACAAAGATAGTA
CGTTTCATATGCCAAATTCAAATGACTGATTAGTAGAGCCTATGTTGAGACAAATCGTAAGAGATCAGCAGAAAAAAATGTCATGATTGATTAGCAATGTCTGCTATGCTCATAGGAATG
GGAACTGGGCACATATGCTATCCATTTGCCATCCTTGGTTTTCAACAGCTCATCACTCTTGGCTGCAGCTCTTTCACAGCCTCCCTCTGCAGAGGTTTAAACCTTCTTACACCCTTTCCT
CTTGATTTTATTCTCCCTCCAGATTATCACCTTTAGGGACTACCTACCCATTTTGCTAGGTGACCACATGCAGAAGTGGATACCCCCATATCAAGGCTACAGTGAATCTGTGGATCCCAG
AATTTCCAATGTCTTCACCTTCGCCTTCCGCTTTGGCCACTTGGAGGTCCCCTCTAGTATGTTCCGCCTGGATGAGAATTATCAGCCATGGGGGCCAGAACCAGAACTCCCCCTCCACAC
CCTCTTCTTCAACACTTGGAGGATGGTCAAAGATGGTATGCCCTTTCAGGGAAGTGCTGTCACCTGGGTCTCCCACTCCGCAGCCTATTGTAGGGAAACTTGGGTTGGAAGTCAGATTCC
AAGCACTTTTACATGACCTTGGGCAAATGAATTCACCTCACTGAGCCTCAGTTTCCTCATTTATAAAATGGGGACAATAATAGTACCCATCTCACGAGGCTATCCAAAACATTAAATGAG
ATATACATGTGGAGCACCCTACAATGGTTCCTGACACACAGGAGGTGATCAATAAATATAAGCTATTCTTTCTTTCCTCTTGGCTTCTAAGATGACTGGGATTTCCCTACCTCCTTTCCC
CGCCCTAGGCTTCTCTGACTTCTACAGGGTTTGGTAAATAAATTGCTCTTTTCTGATCTCTTCTAGAGTTTTTCACTTCATAGAGGTGCCAGAGGTTGGACCCAACTTTCCTTTATCCCT
AGGCTATGTTGTGTTGAAATTAACTTTACTTAAAGCCTAGCAAGTCAAGGACATTTCCTTGAGATTTATGCAACCTCTTCCCATTATGCAACGTTCCTCAGCAGAACATATGGAAGAAAA
AGCTGACTCCATGAACTAGAGCTTTAAAAATACCTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGGGTCTTACTCTGTCACCCAGGCTGGAGTGCAAGGGCGCAATCTCAGCTCACTG
CGGCCTTGACCTCCTGGGCTCACATGATCCTCCTACCTCAGCCTCCCTTGTAGCTGGGATTACAAGGCACACACCCCCATACCTGGCTAATTTTTTTGCCTTTTTTTCAGAGGCGGGGTT
TTGCCATGTTGTCCAGGCTGGTCCCAAACTCCTGGGCTCAAGCAGTCTTCCCACCTTGGCCTCCCAAAGTGTTAGGATTACAGGCATGAGCCACCATGCATGGCCAAAAAATATCTCAAT
GTTTATATTCATGCCATCATCCCATGACTGCCCCTTTCTGCCCACCCCCAGAGCAGACAATCTGGATGCCCCTGTCTCCCTGAGCACACCCTTCAGGCTGCACTGTGCTCTTCTCTCCCT
CCTTCCAGCCTGGGATGTCCAGGTGACCCACATTCAACTAAGAGAAAATGTCTGGTGGAGGCAGAGGCAAGCCATGAATGATGTTCCCACTCTTCCCCCAACCTAAGCATGGCTTCTGGG
TCTCCCTTGGCAGGTGGAATTGATCCTCTGGTGCGGGGCCTGCTGGCCAAGAAATCCAAGCTGATGAAACAGAATAAAATGATGACTGGAGAGCTGCGCAACAAGCTTTTCCAGCCAACT
CACAGGATCCATGGCTTTGACCTGGCTGCCATCAACACACAGCGTTGCCGGGACCATGGGCAACCTGGTGAGTGTCTGAAGTCTGGCCTGCACTGGGGAAATTTTAGCTAACTTTCTAGG
GCTCCTGGAGACTCTCTTCTATAACCCTGAGGATCTGATCATCTGATCAATTCTGAAACAAAAGTCAGGCCAGTTTTTTTTGTTTGAGGTTTTTTTTTTGAGACAGGGTCTTGCTCTGTT
GCCCAGGCTAGAGTACAGCGGTGCGATCACAGCTCACAGCAGCCTCAAACTCCTAGCTTCAAGTAATCCTCCTGCTTAAGCCTACCAAGTAGGTGGGACTACAGGTGTGCCACATGCCCA
GCTTATTTTTTTTTTTAAATATAGACATAGTCTTGCTATGTTGCCCAGGCTGGTCTCGAACTCCTGGGCTCAAGCAATCTCCCACCTTGGCCTCCCAAAGCACTGGCATTACAGGTGCAA
GCCACCATGTCCAGCCCCAGGCCATTCTTAAAACCCACTTTGTTCATCTATGAAACAGAATGTCCCATTTCCCCTAATGCAGAGAAAAGAGCATATATCTGGTACTATCTTGGCATTCCT
TAAATGAAAAAGAGGTCACCAACTAACTTTAAAAACAGTTTAAAAGCCCTGAAAACATTAAGAAAACAATAGAGAGAAACCAATGACTGTTGGACCTTTCTTTTGTCCCCATGAAAGGCA
ATTTAATTAAGAACCAGACTGCCTGAGTTCAAATCCCGCCTATGCCATTTACTAGTTATAAGACTTTGGGCAAATTACTTAACATTTCTATTCTTCATTTACTTATTTGCACAGTGCTTA
GAATAGTGCCTGGACTCATAGTACATACCACATAACTTTCATGATTGCTTAGTGGTTACATAGGACTTAACCAACTAGCCCCCTTAAGATTGAAGTGCAGATAAAAAACAATGGATTCCC
TCCTTCCCCATCCCAAAGGCTGTAAGCCCAGACTTTCTAGGGCTGATAGAGCTGGAGTGGACATGGCCCCAAAGGAGGCTGTGAACAGGAAGTCCCCGGGATGAGACAGCCTCAGTCTCT
CCACCCTAGGGTACAATTCCTGGAGAGCCTTCTGTGACCTCTCACAGCCGCAGACACTAGAGGAGTTGAACACAGTGCTGAAGAGCAAGATGCTGGCCAAGAAGTTACTGGGTCTCTACG
GGACCCCTGACAACATCGACATCTGGATAGGGGCCATTGCTGAGCCGCTGGTGGAAAGGGGTCGGGTGGGGCCTCTCCTGGCCTGCCTCTTGGGCAAGCAGTTCCAGCAGATCCGTGATG
GAGACAGGCAAGTGCGTCCTCAGCCAGGGAGGGAAGGGCAGGGCCCTTCTCCAAGAGGGGTGTCCCAAGGTCCTGCGTGAGCGCTGACTCCGGATCTCAGTGTGAGTAGGGCTTTTCATG
GTCCCTGTGACCCTTTCCTTCCCCTGTGACAGAGTGGGGAGGGGCCAGCGGCCAGACTGTGGAGTGACTCTACTTCTGTCTCTGCAGGTTCTGGTGGGAAAACCCTGGGGTCTTCACGAA
CGAGCAGAAGGACTCTCTACAGAAAATGTCCTTCTCACGCCTTGTCTGTGACAACACCCGCATCACCAAGGTCCCACGGGACCCATTCTGGGCCAACAGCTACCCCTATGACTTCGTGGA
TTGCTCAGCCATCGACAAGCTGGACCTGTCACCCTGGGCCTCAGTGAAGAATTAG

Retrieve as FASTA  
CDS►
Send to BLAST
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2
ATGAGGGTCCTTCTCCATCTCCCAGCCCTCCTGGCTTCCCTCATCTTGCTTCAGGCTGCAGCATCTACCACAAGAGATCCCAGCCTGGACTTGACTTCACTGTCTCTGGAGGTGGGCTGT
GGTGCTCCTGCTCCCGTGGTGAGATGCGACCCGTGCAGCCCTTACCGCACCATTACGGGAGACTGCAATAACAGGAGGAAGCCTGCGCTGGGCGCCGCCAACAGGGCTCTGGCGCGCTGG
CTGCCCGCGGAGTACGAGGACGGGCTCTCCCTGCCCTTCGGCTGGACGCCGGGGAAGACGCGCAACGGCTTCCCTCTCCCGCTGGCCCGGGAGGTATCTAACAAGATTGTTGGCTATCTG
AATGAGGAGGGTGTTCTGGACCAAAACAGGTCCCTGCTCTTCATGCAGTGGGGTCAGATTGTGGATCATGACCTGGACTTTGCCCCTGACACCGAGCTGGGGAGTAGCGAGTACTCCAAA
GCCCAGTGTGATGAGTACTGTATCCAGGGAGACAACTGCTTCCCCATCATGTTCCCACCCAATGACCCCAAGGCGGGGACTCAAGGGAAATGCATGCCTTTCTTCCGAGCTGGGTTCGTC
TGCCCCACTCCACCCTACAAGTCCCTGGCCCGAGAGCAGATCAACGCTCTGACCTCCTTCCTGGATGCCAGCTTTGTGTACAGCTCCGAGCCAAGCCTGGCCAGCCGCCTCCGCAACCTC
AGCAGCCCCCTGGGCCTCATGGCTGTCAACCAGGAGGTCTCAGACCATGGACTACCCTACCTGCCCTATGACAGCAAGAAGCCAAGCCCCTGTGAGTTCATCAACACCACTGCCCGTGTG
CCCTGCTTCCTGGCAGGAGATTCTCGAGCCTCAGAGCATATTCTGCTGGCCACATCCCACACCCTCTTTCTCCGCGAGCATAACCGGCTGGCCAGAGAACTAAAGAGACTCAACCCTCAG
TGGGATGGAGAGAAGCTCTACCAGGAAGCCCGGAAAATCCTGGGAGCCTTCGTGCAGATTATCACCTTTAGGGACTACCTACCCATTTTGCTAGGTGACCACATGCAGAAGTGGATACCC
CCATATCAAGGCTACAGTGAATCTGTGGATCCCAGAATTTCCAATGTCTTCACCTTCGCCTTCCGCTTTGGCCACTTGGAGGTCCCCTCTAGTATGTTCCGCCTGGATGAGAATTATCAG
CCATGGGGGCCAGAACCAGAACTCCCCCTCCACACCCTCTTCTTCAACACTTGGAGGATGGTCAAAGATGGTGGAATTGATCCTCTGGTGCGGGGCCTGCTGGCCAAGAAATCCAAGCTG
ATGAAACAGAATAAAATGATGACTGGAGAGCTGCGCAACAAGCTTTTCCAGCCAACTCACAGGATCCATGGCTTTGACCTGGCTGCCATCAACACACAGCGTTGCCGGGACCATGGGCAA
CCTGGGTACAATTCCTGGAGAGCCTTCTGTGACCTCTCACAGCCGCAGACACTAGAGGAGTTGAACACAGTGCTGAAGAGCAAGATGCTGGCCAAGAAGTTACTGGGTCTCTACGGGACC
CCTGACAACATCGACATCTGGATAGGGGCCATTGCTGAGCCGCTGGTGGAAAGGGGTCGGGTGGGGCCTCTCCTGGCCTGCCTCTTGGGCAAGCAGTTCCAGCAGATCCGTGATGGAGAC
AGGTTCTGGTGGGAAAACCCTGGGGTCTTCACGAACGAGCAGAAGGACTCTCTACAGAAAATGTCCTTCTCACGCCTTGTCTGTGACAACACCCGCATCACCAAGGTCCCACGGGACCCA
TTCTGGGCCAACAGCTACCCCTATGACTTCGTGGATTGCTCAGCCATCGACAAGCTGGACCTGTCACCCTGGGCCTCAGTGAAGAATTAG

Retrieve as FASTA